Advances in bioscience and clinical medicine最新文献

{"title":"Internal Trauma, Humeral Fracture, and Radial Nerve Paralysis: How Could it Occur in the Sport Setting? A Case Report and Review of the Literature","authors":"Elghoul Naoufal, Elantri Ismail, Bouya Ayoub, Bennis Azzelarab, Z. Omar, Tanane Mansour, Jaafar Abdeloihab","doi":"10.7575/aiac.abcmed.v.8n.1p.1","DOIUrl":"https://doi.org/10.7575/aiac.abcmed.v.8n.1p.1","url":null,"abstract":"Thrower’s fractures are Spiral fractures of the humerus in the ball. They represent very uncommon clinical entities that can simulate pathologic fractures. Moreover, the concomitant neurologic deficient is rare. Herein we report a 27 years old muscular man presented a spiral fracture of the humerus following a forceful throw of the ball during an amateur throwing challenge. Clinical and imaging findings showed a displaced Thrower fracture with radial nerve neurapraxia (known as Holstein Lewis fracture) prompting the patient to undergo surgery. The intraoperative aspect found that the nerve was near to the beveled distal humeral fragment with no incarceration. We performed an internal fixation using the Leicester plate and the nerve was kept away from the plate by the interposition of a soft tissue sheet. At the last follow up, the fracture united and radial nerve neurapraxia resolved and the patient regained the full range of motion of his right upper limb with no pain. In conclusion, although this type of fracture is rare, given their significant morbidity, we emphasize that the reactional throwers should undergo appropriate preseason training before practicing a throwing challenge or generally a throwing sport.","PeriodicalId":92322,"journal":{"name":"Advances in bioscience and clinical medicine","volume":"8 1","pages":"1-5"},"PeriodicalIF":0.0,"publicationDate":"2020-01-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42294229","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessment of Strain Changes in the Triple Layers of Left Ventricle in Normotensive Versus Hypertensive Patients","authors":"M. Toufan, Naser Khezerlou Aghdam, Venus Shahabi Raberi","doi":"10.7575/aiac.abcmed.v.8n.1p.20","DOIUrl":"https://doi.org/10.7575/aiac.abcmed.v.8n.1p.20","url":null,"abstract":"The phenomenon of left ventricular remodeling caused by hypertension is a well-known affair that can be evaluated through echocardiography techniques. In recent decade, modern echocardiographic methods such as speckle tracking echocardiography have been used to evaluate left ventricular mechanical changes in hypertensive conditions. The evaluation of the strain index as an important part of the evaluation of the ventricular wall in various ventricular layers has been highly regarded in hypertensive patients. In this regard, the left global ventricular longitudinal strain (GLS) especially in the three ventricular wall layers can strongly predict mortality and morbidity of cardiovascular disease. Given that hypertensive disease is one of the most important risk factors for the development of heart failure and systolic and diastolic cardiovascular dysfunction, even in cases with preserved left ventricular ejection fraction, the exact determination of ventricular strain changes in various layers in hypertensive states would be  beneficial for preventing hypertensive cardiomyopathy. In a cross-sectional study, we assessed strain changes in the triple layers of the ventricular wall in hypertensive and normotensive individuals with presence or absence of left ventricular diastolic dysfunction. In this study, both global longitudinal strain (GLS) and global circumferential strain (GCS) indices in endocardial, myocardial and epicardial layers were evaluated. We also considered the effect of diastolic ventricular dysfunction as an important confounder with the effect of hypertension on the ventricular strain. An important finding of this study was the significant effect of hypertension on reducing GLS and GCS in mid myocardial and epicardial layers in the presence of left ventricular diastolic dysfunction. At first, in case of hypertension, the presence of diastolic dysfunction in reducing the strain of the left ventricular wall seems to be necessary as a trigger factor; thus in hypertensive cases with preserved diastolic function, the strain change in left ventricular wall may not be evident. Secondly, reduction in the ventricular wall strain in the endocardial layer was not revealed but it seems that the exacerbation of uncontrolled hypertension may also lead to endocardial involvement as shown by prior studies. In total, proper control of blood pressure in patients with a history of hypertension, especially in the field of left ventricular diastolic dysfunction will improve the function of the left ventricular wall and thus improve the prognosis of these patients. Disturbance in left ventricle wall layers in the field of hypertension has been studied and confirmed in several studies, although the effective role of diastolic dysfunction has been studied less. For instance, in a study by Tadic et al., GLS was significantly lower in hypertensive than in normotensive patients (1). In Navarini et al study, although no difference was found in left ventricular","PeriodicalId":92322,"journal":{"name":"Advances in bioscience and clinical medicine","volume":"8 1","pages":"20-21"},"PeriodicalIF":0.0,"publicationDate":"2020-01-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43707444","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of Primary Patency and Maturation Rate of Antecubital Artriovenous Fistula for Dialysis in Diabetic Patient with Two Methods: Regional Block with Ropivacaine 0.5% and Local Anesthesia with Lidocaine 2%","authors":"N. Tadayon, N. Tajiknia, M. Mozaffar, F. Behnaz, Houman Teymourian","doi":"10.7575/aiac.abcmed.v.7n.4p.5","DOIUrl":"https://doi.org/10.7575/aiac.abcmed.v.7n.4p.5","url":null,"abstract":"Background: The best arteriovenous access in diabetic patients under dialysis is crucial to attain better therapeutic outcomes and improved prognosis in the patients. The purpose in this study was to compare the primary patency and maturation rate of antecubital artriovenous fistula for dialysis in diabetic patient with two methods: regional block with Ropivacaine 0.5% and local anesthesia with lidocaine 2%. Methods and Materials: In this randomized clinical trial, 40 consecutive diabetic patients under dialysis in 2016 and 2017 in a training center were enrolled and the primary patency and maturation rate of antecubital artriovenous fistula were compared with regional block with Ropivacaine 0.5% versus local anesthesia with lidocaine 2%. Results: The results in this study demonstrated that all factors of final arterial and venous diameter, blood flow, and patency were higher in group under regional block with Ropivacaine 0.5% and all except patency showed significant difference (P 0.05). Conclusion: Totally, according to the obtained results, it may be concluded that regional block with Ropivacaine 0.5% is superior to local anesthesia with lidocaine 2% leading to higher patency rate and shorter maturation time and also higher arteriovenous diameter and blood flow.","PeriodicalId":92322,"journal":{"name":"Advances in bioscience and clinical medicine","volume":"7 1","pages":"5-8"},"PeriodicalIF":0.0,"publicationDate":"2020-01-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44973535","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Relationship between Demographic Factors in Adult Patients with Stroke","authors":"S. Shams-Vahdati, A. Ala, E. Sadeghi-Hokmabad, N. Parnianfard, Nasim Ahmadi Sepehri, Maedeh Gheybi","doi":"10.7575/aiac.abcmed.v.7n.4p.14","DOIUrl":"https://doi.org/10.7575/aiac.abcmed.v.7n.4p.14","url":null,"abstract":"Background: Developing countries are challenging with stroke as the third cause of death in developed countries and the most popular neurologic disease which results in disability. This study was designed to assess the relationship between demographic factors and early outcome in adult patients with difference type of stroke. Methods and Materials: A retrospective register review was performed from March 2017 to March 2018. ED medical document (chart) were reviewed by a neurologist or physician to obtain the clinical diagnosis, patient characteristics. Their demographic data (such as age, gender), NIHSS score and MRS score were filled in questionnaire. the significant variables were verified in a multivariable model to achieve an attuned estimate of effect. Results: A total of 861 patients with stroke were included in the analysis; the male and female sex in the statistical population were 56% and 43%; the mean age of the patients was 14.32 ± 61.74. The mean NIHSS (16.08±10.51) & MRS (3.66) scores were evaluated, respectively 47% severe stroke (NICHSS>16). There was no significant relationship between age increase and NIHSS increase (P = 0.86). Conclusion: Aging has a significant relationship with increased stroke. Gender and age differences in risk of stroke outcomes are mostly described by variations in physical characteristics and stroke severity of the patients.","PeriodicalId":92322,"journal":{"name":"Advances in bioscience and clinical medicine","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-01-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46774477","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Survey of Relation between Midcycle Progesterone Level with IUI Cycles Success Rate","authors":"A. Ghasemzadeh, Gilda Mostafavi, M. Nouri, P. Chaichi, L. Farzadi, P. Hakimi","doi":"10.7575/aiac.abcmed.v.7n.4p.9","DOIUrl":"https://doi.org/10.7575/aiac.abcmed.v.7n.4p.9","url":null,"abstract":"Introduction: Assisted reproductive technology is used routinely for treatment of infertile spouses. Previous studies reported conflicting results regarding effect of progesterone rise at the HCG injection day. The aim of current study is to evaluate the effects of mid cycle progesterone levels in IUI cycles. Methods: In this analytical cross-sectional study, the outcome of treatment in 200 IUI cycles were evaluated. Patients’ demographic findings, progesterone level at the day of HCG injection, number of follicles >16 mm, endometrial thickness and clinical pregnancy rate were recorded. For better evaluation, progesterone levels were divided to 1.5 ng/dl. Results: Patients’ mean age was 29.70±4.38 years. The progesterone levels of 1.5 ng/dl was detected in 24.5%, 56% and 19.5% of patients, respectively. The rate of clinical pregnancy was 27.5%. Cases with positive pregnancy had significantly lower progesterone levels (0.88±0.31 vs.1.11±0.80, p=0.04). The highest pregnancy rate was in progesterone levels 0.5-1.5 compared to levels 1.5 ng/dl (42% vs. 12.2% vs. 5.2%, p 16 mm(r=0.02, p=0.77). Conclusion: The results of current study showed that the increase in progesterone levels at the day of HCG injection accompanies with lower pregnancy rate. However, this increase has no correlation with number of mature follicles and endometrial thickness.","PeriodicalId":92322,"journal":{"name":"Advances in bioscience and clinical medicine","volume":"7 1","pages":"9-13"},"PeriodicalIF":0.0,"publicationDate":"2020-01-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41659224","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of Calcitonin on Healing Duration, Function and Pain Relief in Patients with Maxillofacial Fractures. A pilot study","authors":"J. Yazdani, F. Ahmadpour","doi":"10.7575/aiac.abcmed.v.7n.4p.1","DOIUrl":"https://doi.org/10.7575/aiac.abcmed.v.7n.4p.1","url":null,"abstract":"Introduction: Calcitonin is a polypeptide hormone regulating the metabolism calcium in the body. Many studies showed that calcitonin had analgesic effect on several painful circumstances. The aim of this study was to determine the effects of intranasal calcitonin during the immediate postoperative period on postoperative pain in patients undergoing maxillofacial fracture surgery. Materials and Methods: In this clinical trial which was conducted in April 2019 in Imam Reza Hospital of Tabriz, 16 patients with maxillofacial fracture were divided randomly into two groups. The intervention group was given 200UI of intranasal calcitonin and the control group received nasal spray of NaCl. The severity of pain was then evaluated daily for up to seven days after the operation, with the severity of: no pain (0) to the most severe pain (10) using visual analog scale for pain. The daily dose of analgesic was also measured. The patients were allowed to request 250 mg of injectable acetaminophen each day up to a maximum daily dose of 4 g (maximum permissible dose) in the event of pain. Results: The results show that the pain intensity between two groups was not significantly different. However in the seventh day the total acetaminophen consumption was significantly lower in the intervention group. Conclusion: calcitonin may be a useful medication to help to control the post operative pain by reducing the required dose of routine painkillers.","PeriodicalId":92322,"journal":{"name":"Advances in bioscience and clinical medicine","volume":"7 1","pages":"1-4"},"PeriodicalIF":0.0,"publicationDate":"2020-01-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42812314","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of Glasgow Blatchford Score and AIMS65 in Predicting Mortality in Patients with Upper Gastrointestinal Bleeding","authors":"Nasser Hajavi, K. Isazadehfar, Mohammad Hosseyn Hosseyni, A. Habibzadeh, Elham Yousefi Ardabili","doi":"10.7575/aiac.abcmed.v.7n.4p.17","DOIUrl":"https://doi.org/10.7575/aiac.abcmed.v.7n.4p.17","url":null,"abstract":"Introduction: Upper gastrointestinal bleeding (UGIB) is the most common cause of emergency admission in gastrointestinal disease. UGIB could accompany with adverse events if not treated timely. Different scoring systems have been suggested for diagnosing these patients, In this study we aimed to compare the predictive value of two scoring systems AIMS65 and Glasgow Blatchfors scale (GBS) in patients with UGIB. Methods: In this cross-sectional study, 153 patients (71.9% male with mean age of 56.72±21.64 years) with acute UGIB between April 2017 and September 2018 were included. Demographic findings, past medical history, laboratory findings, AMIS65 and GBS score, as well as, need for urgent endoscopy, transfusion and mortality were recorded. Both methods value in predicting the outcomes were measured using ROC curves. Results and Conclusion: Urgent endoscopy was performed in 44.4%. The most common finding was peptic ulcer with mostly clean base type. Rebleeding occurred in 15%, need for transfusion was in 44.4% and mortality rate was 5.2%. AIMS65 compared to GBS was superior in predicting mortality (AUC of 0.947 vs. 0.80) but was inferior compared to GBS in predicting need for transfusion (0.849 vs. 0.947). None of the systems could predict the need for urgent endoscopy. AIMS65 with cut off 2 and 0 and GBS with cut off of 12 and 8 could predict mortality and need for transfusion. GBS seems a better system in predicting the need for blood transfusion, while AIMS65 is better system for predicting in-hospital mortality in patients with UGIB.","PeriodicalId":92322,"journal":{"name":"Advances in bioscience and clinical medicine","volume":"7 1","pages":"17-21"},"PeriodicalIF":0.0,"publicationDate":"2020-01-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43814879","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Castleman Disease in the Buccal Space Mimicking Lymphoma: A Case Report","authors":"M. Hashemi, J. Yazdani, Amir Hossein Bani Shah Abadi, Tannaz Abdollah Zade Baghai, Behrouz Shokouhi","doi":"10.7575/aiac.abcmed.v.7n.3p.23","DOIUrl":"https://doi.org/10.7575/aiac.abcmed.v.7n.3p.23","url":null,"abstract":"Castleman disease is a benign lymphoproliferative disorder of unknown etiology, more commonly appearing in the mediastinum. Craniofacial involvement is rare. Surgical excision is the only intervention needed for the unicentric type, while systemic treatment would be necessary for the multicentric type. Here, we report a rare case of unicentric castleman disease of the buccal space of a 23-year-old woman. Additionally, we review the radiological and histopathological features of this lesion.","PeriodicalId":92322,"journal":{"name":"Advances in bioscience and clinical medicine","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43683877","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Methods of Preventing Hospital Acquired Infection","authors":"F. Bashar","doi":"10.7575/aiac.abcmed.v.7n.3p.13","DOIUrl":"https://doi.org/10.7575/aiac.abcmed.v.7n.3p.13","url":null,"abstract":"Hospital-acquired infections can increase the rate of morbidity and mortality as well as medical costs. Nosocomial infection is spread by various ways such as surgical, intravenous catheters, surface contact (like as hands) and also through the air. Some interventions include appropriate hand and surface decontamination, sufficient staffing, improved ventilator management, usage of coated central venous and urinary catheters have all been linked with considerably lower rate of nosocomial infection. Multiple interventions simultaneously are required for comprehensive infection control and multiple actions may be given better outcome rather than a single action. Some multiple infection control protocols will possibly show more effective result instead of employing a single or few strategies. Several non-pharmacological interventions to prevent HAIs will reduce the requirement for prolonged or multiple-drug antibiotic courses for infected patients. And lower antibiotic usage will decrease risk of antibiotic-resistant organisms and may improve effectiveness of antibiotics therapy to patients with acquired infections.","PeriodicalId":92322,"journal":{"name":"Advances in bioscience and clinical medicine","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47229057","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Mislead Human Bite Cause a Septic Arthritis with Articular Destruction of the Fifth Metacarpophalangeal Joint: A Case Report and Review of the Literature","authors":"N. Elghoul, A. Zine, A. Jaafar","doi":"10.7575/aiac.abcmed.v.7n.3p.20","DOIUrl":"https://doi.org/10.7575/aiac.abcmed.v.7n.3p.20","url":null,"abstract":"Due to severe and fatal complications that can cause the human bite injuries to the joint; these injuries were described as “the cancer of the hand”. Human bites are less common than domestic animal bites, accounting for only 2% of hand bites. Moreover, if a human bite wound occurred in the hand, it may lead to severe infection as septic arthritis and osteomyelitis which its incidence account about only 2%. Herein, we report a rare case of a 22 years old man who presented a “minor” wound of the hand due to clenched fist human bite, managed initially inadequately leading to massive destruction of the fifth metacarpophalangeal joint, prompting the patient to undergo surgery. In the operating theater, we realized a debridement of devitalized tissue, collection of bacteriological samples and we curetted the joint surfaces along with copious irrigation with saline serum (2 liters). One gram of Amoxicillin-clavulanic acid were administrated after realizing bacteriological samples then one gram every eight hours. The wound was left open and closed secondary. Then, a dressing with betadine was applied followed by careful clinical and biological daily monitoring along with an early postoperative range of motion. At the last follow up, the patient showed no sign of infection with no pain but he kept a residual stiffness of his fifth finger. Through this observation, we emphasize that physicians should be alert about the danger if this injury is underestimated.","PeriodicalId":92322,"journal":{"name":"Advances in bioscience and clinical medicine","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41813137","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}