Brazilian dental journal最新文献

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Effect of horizontal slot of maxillary canines’ brackets with varying wire angulations - An in vitro study 不同金属丝角度对上颌犬托槽水平槽位影响的体外研究
Brazilian dental journal Pub Date : 2022-10-01 DOI: 10.1590/0103-6440202205104
Márcio Crestana Cantarelli, Ana Paula Terossi de Godoi, M. Sinhoreti, J. Neves, E. A. Santos, L. Correr-Sobrinho, A. R. Costa
{"title":"Effect of horizontal slot of maxillary canines’ brackets with varying wire angulations - An in vitro study","authors":"Márcio Crestana Cantarelli, Ana Paula Terossi de Godoi, M. Sinhoreti, J. Neves, E. A. Santos, L. Correr-Sobrinho, A. R. Costa","doi":"10.1590/0103-6440202205104","DOIUrl":"https://doi.org/10.1590/0103-6440202205104","url":null,"abstract":"Abstract A new device was developed to enable the visualization and measurement of canine angulation while at the same time visualizing and measuring the force transmitted to adjacent teeth. This study aimed to evaluate the mesiodistal tilt angle of the upper canine brackets, the wire deflection, and its effects on adjacent teeth with five different slot designs of upper canines. Wires (0.020” and 0.019” x 0.025”) were tested on different five bracket types at five different distal angles. The force applied to adjacent teeth was measured as the angle was increased, and its consequences were observed in the posterior and anterior regions as well. The force tension (gf) was measured in a universal testing machine. Data were submitted to a 3-way ANOVA and Tukey’s test (α=0.05). For both arches, regardless of the type of tooth and bracket type, the highest means tension mean values were shown by the 20° angle, followed by the 15°,10°, and 5° angles, which differed statistically among themselves. Overall, for 5°, 10°, and 15° angles, conventional and versatile brackets showed significantly higher force values in all teeth, tip-edge and control brackets showed the lowest. The highest force values were observed in central and lateral incisors with conventional and versatile brackets and on first and second premolar teeth with self-ligating passive and control brackets. Conventional brackets presented the highest forces, tip-edge and control brackets showed the lowest. The teeth that suffered the greatest forces were lateral incisors, and those that suffered the least were second premolars.","PeriodicalId":9211,"journal":{"name":"Brazilian dental journal","volume":"33 1","pages":"55 - 63"},"PeriodicalIF":0.0,"publicationDate":"2022-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42478652","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effects of argon plasma and aging on the mechanical properties and phase transformation of 3Y-TZP zirconia 氩等离子体和时效对3Y-TZP氧化锆力学性能和相变的影响
Brazilian dental journal Pub Date : 2022-10-01 DOI: 10.1590/0103-6440202204849
W. Negreiros, M. Cotta, F. Rueggeberg, J. Bonvent, F. D. Nascimento, M. Giannini
{"title":"Effects of argon plasma and aging on the mechanical properties and phase transformation of 3Y-TZP zirconia","authors":"W. Negreiros, M. Cotta, F. Rueggeberg, J. Bonvent, F. D. Nascimento, M. Giannini","doi":"10.1590/0103-6440202204849","DOIUrl":"https://doi.org/10.1590/0103-6440202204849","url":null,"abstract":"Abstract To evaluate the flexural strength (FS) and flexural modulus (FM) of a commercial 3Y-TZ0P ceramic after artificial aging and either without or with two application times of non-thermal plasma treatments (NTP). In addition, changes in crystalline phase transformation and surface nano-topography after NTP application, during different aging periods, were evaluated. Ninety 3Y-TZP bars (45x4x3 mm) were made for FS and FM testing, and assigned to nine groups (n=10): no NTP/no aging (Control); no NTP/4h aging; no NTP/30h aging; 10s NTP/no aging; 10s NTP/4h aging; 10s NTP/30h aging; 60s NTP/no aging; 60s NTP/4h aging and 60s NTP/30h aging. Artificial accelerated aging was simulated using an autoclave (134º C at 2 bar) for up to 30h. FS and FM were assessed using a universal testing machine and data analyzed using a ANOVA and Tukey test (α=0.05). The volume change in zirconia monoclinic phase (MPV) was evaluated using X-ray diffraction and surface nano-topography was assessed using atomic force microscopy (baseline until 30h-aging). NTP application did not influence the FS and FM of zirconia. Compared to the Control (no NTP/no aging), the FS of zirconia samples treated for 30 hours in autoclave (“no NTP/30h aging” group) increased. Artificial aging for 30 hours significantly increased the FM of zirconia, regardless of NTP application. MPV tended to increase following the increase in aging time, which might result in the surface irregularities observed at 30h-aging. NTP did not alter the zirconia properties tested, but 30h-aging can change the zirconia FS, FM and MPV.","PeriodicalId":9211,"journal":{"name":"Brazilian dental journal","volume":"33 1","pages":"100 - 107"},"PeriodicalIF":0.0,"publicationDate":"2022-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44254004","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effect of surrounded shade and specimen`s thickness on color adjustment potential of a single-shade composite 包围阴影和样品厚度对单一阴影复合材料颜色调节潜力的影响
Brazilian dental journal Pub Date : 2022-10-01 DOI: 10.1590/0103-6440202204973
M. S. Barros, Paula Fernanda Damasceno Silva, M. L. Santana, R. Bragança, A. Faria-E-Silva
{"title":"Effect of surrounded shade and specimen`s thickness on color adjustment potential of a single-shade composite","authors":"M. S. Barros, Paula Fernanda Damasceno Silva, M. L. Santana, R. Bragança, A. Faria-E-Silva","doi":"10.1590/0103-6440202204973","DOIUrl":"https://doi.org/10.1590/0103-6440202204973","url":null,"abstract":"Abstract This study evaluated the effect of surrounded shade and specimens` thickness on the color adjustment potential (CAP) of a single-shade composite. The composite Vittra APS Unique was surrounded (dual specimens) or not (simple specimens) by a control composite (shade A1, A2, or A3). Simple specimens of the control composite were also confectioned. Opacity and whiteness index for dentistry (WID) were calculated for simple specimens. Color differences between the simple (ΔE*SIMPLE)/ dual specimens (ΔE*DUAL) and the controls were calculated. CAP was calculated based on the ratio between ΔE* SIMPLE and ΔE* DUAL. The tested composite presented lower opacity (53 to 62% vs. 80 to 93%) and higher WID (≈ 42 vs. 18 to 32) than controls. Irrespective of the specimens’ thickness (1.0/ 1.5 mm), the lowest values of ΔE* SIMPLE (11.1/ 10.8) and ΔE*DUAL (7.2/ 6.1) were observed using the surrounding shade A1. The shade A3 yielded higher ΔE*SIMPLE (16.4/ 17.1) and ΔE* DUAL (11.3/ 12.3) than the A2 (ΔE*SIMPLE = 13.4/ 14.6; and ΔE* DUAL = 9.7/ 10.3). The specimen`s thickness significantly affected the CAP (0.35 and 0.44 for 1.0 and 1.5 mm, respectively) only for shade A1, which had the highest CAP values. The shade A3 resulted in higher CAP values (0.31) than A2 (0.27) when 1.0-mm thick specimens were used, but similar values were observed for 1.5 thick specimens (≈ 0.29). In conclusion, both surrounding shade and specimen thickness can affect the CAP of a single-shade resin composite.","PeriodicalId":9211,"journal":{"name":"Brazilian dental journal","volume":"33 1","pages":"126 - 132"},"PeriodicalIF":0.0,"publicationDate":"2022-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41413638","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Oral mucoceles: A Brazillian Multicenter Study of 1,901 Cases 口腔黏液囊肿:巴西1901例多中心研究
Brazilian dental journal Pub Date : 2022-10-01 DOI: 10.1590/0103-6440202204965
Georgea Gabriela Barreto Miranda, Samuel de Carvalho Chaves-Junior, Matheus Paschoaletto Lopes, Talytha Barbosa da Rocha, Débora Frota Colares, F. A. Ito, I. L. Cavalcante, R. Cavalcante, Bruno Augusto Benevenuto de Andrade, C. Nonaka, P. Alves, R. Albuquerque-Júnior, J. Cunha
{"title":"Oral mucoceles: A Brazillian Multicenter Study of 1,901 Cases","authors":"Georgea Gabriela Barreto Miranda, Samuel de Carvalho Chaves-Junior, Matheus Paschoaletto Lopes, Talytha Barbosa da Rocha, Débora Frota Colares, F. A. Ito, I. L. Cavalcante, R. Cavalcante, Bruno Augusto Benevenuto de Andrade, C. Nonaka, P. Alves, R. Albuquerque-Júnior, J. Cunha","doi":"10.1590/0103-6440202204965","DOIUrl":"https://doi.org/10.1590/0103-6440202204965","url":null,"abstract":"Abstract Oral mucocele (OM) is the most common lesion of minor salivary glands. The present study aimed to report the clinical and demographic features of a large series of OMs and identify possible predictive variables associated with the recurrence rate of these lesions. A retrospective descriptive cross-sectional study was performed. A total of 43,754 biopsy records from four pathology services in Brazil were analyzed. All cases of OMs were reviewed, and clinical and demographic data were collected. The study comprised 1,002 females (56.2%) and 782 males (43.8%), with a mean age of 19.8±16.4 years (range: 01-87 years) and a 1.3:1 female-to-male ratio. The lower lip (n=1,160; 67.4%), and floor of the mouth (n=172; 10.0%), were the most common affected sites, presenting clinically as nodules (n=978; 79.4%) of smooth surface (n=428; 77.5%) and normal color (n=768, 46.7%). Excisional biopsy was the treatment in most cases (n=1,392; 78.0%). Recurrent OMs represented 6.2% of all diagnosed cases (n=117). OMs recurred more commonly in younger patients (aged<20 years) (p<0.0001), in lesions larger than 2 cm in diameter (p<0.0001), and in those located in the ventral tongue (p=0.0351). Also, recurrence rates were higher significantly in cases treated with laser surgery than in those with conventional surgery (p=0.0005). Patients with OMs should be carefully informed of its possible recurrence, especially when found on the ventral tongue of young patients.","PeriodicalId":9211,"journal":{"name":"Brazilian dental journal","volume":"33 1","pages":"81 - 90"},"PeriodicalIF":0.0,"publicationDate":"2022-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43889057","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Can non-carious cervical lesions depth affect clinical response in pain intensity and remaining dentin thickness? 非龋齿性宫颈病变的深度会影响疼痛强度和剩余牙本质厚度的临床反应吗?
Brazilian dental journal Pub Date : 2022-10-01 DOI: 10.1590/0103-6440202204789
A. M. Galvão, Ramon Corrêa de Queiroz Gonzaga, Maria Antonieta Veloso Carvalho de Oliveira, A. C. Machado, G. Barbosa, P. V. Soares, G. R. Silva
{"title":"Can non-carious cervical lesions depth affect clinical response in pain intensity and remaining dentin thickness?","authors":"A. M. Galvão, Ramon Corrêa de Queiroz Gonzaga, Maria Antonieta Veloso Carvalho de Oliveira, A. C. Machado, G. Barbosa, P. V. Soares, G. R. Silva","doi":"10.1590/0103-6440202204789","DOIUrl":"https://doi.org/10.1590/0103-6440202204789","url":null,"abstract":"Abstract Non-carious Cervical Lesions (NCCL) are dental tissue defects, non-related to caries, frequently observed in the dental practice. The aim of this study was to evaluate the effects of NCCL on dentin depth and thickness and the response to dental pain by means of clinical diagnostic tests. 86 teeth from 14 patients with NCCL were assessed by: depth of NCCL, clinical tests (evaporative stimulus, to detect pain levels of dentin hypersensitivity, cold thermal test to classify pulp health, percussive stimuli to evaluate the periradicular tissues and cone beam computed tomography (tomography to evaluate remaining dentin thickness (RDT). In terms of depth, the sample was divided into two groups: G1- teeth with NCCLs ≤1.0mm and G2- teeth with NCCLs between 1.1-2.0 mm. Dental pain data were compared by Mann-Whitney test and RDT by Student’s t-test and correlations by the Pearson test (p<0.05). The depth of NCCL does not influence dental pain response to evaporative stimulus (p=0.129), cold thermal test (p = 0.125), vertical (p = 0.317) and horizontal (p = 0.119) percussion clinical diagnostic tests. However, G1 showed more RDT (p<0.001), and the correlation test showed that deeper NCCL presents smaller remaining dentin thickness (p=0.011/r=-0.273). In conclusion, tooth with NCCL up to 2mm-depth presents similar levels of pain for dentin hypersensitivity, pulp and periradicular tissue independent to NCCL depth, however, lesions with ≤1.0mm-depth showed greater RDT in tomographic findings.","PeriodicalId":9211,"journal":{"name":"Brazilian dental journal","volume":"33 1","pages":"108 - 115"},"PeriodicalIF":0.0,"publicationDate":"2022-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47928341","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Evaluation of Removal Force in Prosthetic Components of Morse Taper Dental Implants Morse锥牙种植体修复部件去除力的评价
Brazilian dental journal Pub Date : 2022-10-01 DOI: 10.1590/0103-6440202205084
Angelo Marcelo Tirado Dos Santos, G. A. V. Stabile, K. R. Felizardo, Sérgio Eduardo Ramos Dos Santos Júnior, S. Berger, R. Guiraldo, Alcides Gonini Júnior, M. Lopes
{"title":"Evaluation of Removal Force in Prosthetic Components of Morse Taper Dental Implants","authors":"Angelo Marcelo Tirado Dos Santos, G. A. V. Stabile, K. R. Felizardo, Sérgio Eduardo Ramos Dos Santos Júnior, S. Berger, R. Guiraldo, Alcides Gonini Júnior, M. Lopes","doi":"10.1590/0103-6440202205084","DOIUrl":"https://doi.org/10.1590/0103-6440202205084","url":null,"abstract":"Abstract The longevity of prosthetic rehabilitation is determined by the stability of the implant and abutment interfaces. True morse taper connections on dental restorations have been effective, however activation force still empirical. This work compared the activation strength and internal contact of Morse taper system according to the removal force. Eighty sets, composed of implants and prosthetic abutments, were evaluated with different internal contact areas; 15.12mm2 (G3.3) and 21.25mm2 (G4.3). The specimens were activated at 0° and 30°, with loads of 10, 20, 40 and 60N. The specimens were submitted to tensile test and the data to ANOVA and Tukey’s tests (α=0.05). Representative specimens were examined under SEM. Removal force of G3.3 (2.15±1.33MPa) did not differed to G4.3 (1.99±1.03MPa). The activation at 0º (2.95±0.98MPa) statistically differed to 30º (1.19±0.54MPa). The 60N load was statistically superior for G3.3 and there was no statistical difference between 20N to 60N in G4.3. The values of 10N at 30o and 20N at the long axis of the morse taper implant, independent of the frictional contact area showed the best settlement.","PeriodicalId":9211,"journal":{"name":"Brazilian dental journal","volume":"33 1","pages":"74 - 80"},"PeriodicalIF":0.0,"publicationDate":"2022-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49564538","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Physico-chemical properties of calcium silicate-based sealers in powder/liquid and ready-to-use forms 粉状/液体和即用型硅酸钙基封口剂的物理化学性质
Brazilian dental journal Pub Date : 2022-10-01 DOI: 10.1590/0103-6440202204832
A. Janini, L. E. Pelepenko, B. P. Gomes, M. Marciano
{"title":"Physico-chemical properties of calcium silicate-based sealers in powder/liquid and ready-to-use forms","authors":"A. Janini, L. E. Pelepenko, B. P. Gomes, M. Marciano","doi":"10.1590/0103-6440202204832","DOIUrl":"https://doi.org/10.1590/0103-6440202204832","url":null,"abstract":"Abstract Calcium silicate-based root canal sealers have been developed in powder/liquid or premixed ready-to-use forms. The evaluation of the physico-chemical properties of a prototype powder/liquid MTApex Sealer (Ultradent) in comparison to a ready-to-use material EndoSequence BC Sealer (Brasseler) was performed. The paste/paste epoxy resin-based AH Plus (Dentsply) served as control for comparisons. The sealers were evaluated (n = 6) regarding setting time (in dry and moist environments), flow and radiopacity, following the ISO-6876/2012 standard. Also, the pH was assessed. Material’s surface and chemical characterization was evaluated using scanning-electron-microscopy (SEM) and energy-dispersive-spectrometry (EDS). Mixed ANOVA, Shapiro-Wilk, Levene, and post-hoc analysis with Bonferroni correction were performed at a significance level of 5%. MTApex Sealer exhibited the highest flow and EndoSequence BC Sealer had a significantly longer setting time in dry compared to the moist environment; however, for MTApex Sealer and AH Plus no significant changes occurred when additional moisture was provided. All materials exceeded 7 mm Al of radiopacity and showed a decreasing alkalinity over the 21 day-analysis. SEM/EDS evaluation resulted in peaks of calcium, silicon, and the respective radiopacifier. The prototype powder/liquid MTApex Sealer had the highest flow and similar setting time in both dry and moist environments; opposingly, EndoSequence BC Sealer was crucially influenced by external moisture. This suggests that the powder/liquid materials’ setting seems to be more predictable.","PeriodicalId":9211,"journal":{"name":"Brazilian dental journal","volume":"33 1","pages":"18 - 25"},"PeriodicalIF":0.0,"publicationDate":"2022-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41580507","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 4
Immunohistochemical analysis of SHH, SMO and GLI-1 proteins in epithelial odontogenic lesions 上皮性牙源性病变中SHH、SMO和gli1蛋白的免疫组织化学分析
Brazilian dental journal Pub Date : 2022-10-01 DOI: 10.1590/0103-6440202204972
K. S. Rodrigues, H. Santos, E. Morais, R. Freitas
{"title":"Immunohistochemical analysis of SHH, SMO and GLI-1 proteins in epithelial odontogenic lesions","authors":"K. S. Rodrigues, H. Santos, E. Morais, R. Freitas","doi":"10.1590/0103-6440202204972","DOIUrl":"https://doi.org/10.1590/0103-6440202204972","url":null,"abstract":"Abstract The present study analyzed the expression of proteins involved in the sonic hedgehog signaling pathway (SHH, SMO, and GLI-1) in benign epithelial odontogenic lesions (odontogenic keratocyst - OKC, ameloblastoma - AB, and adenomatoid odontogenic tumor - AOT) in order to identify the role of these proteins in the pathogenesis of these lesions. The sample consisted of 20 OKCs, 20 ABs, and 10 AOTs. The Kruskal-Wallis, Mann-Whitney U, and Spearman’s (r) tests were used for statistical analysis, with the level of significance set at 5% (p < 0.05). The membrane/cytoplasmic expression of SHH was significantly higher in AB compared to AOT (p = 0.022) and OKC (p = 0.02). No differences were found in the membrane/cytoplasmic expression of SMO between the lesions studied. Regarding GLI-1, significant differences were observed at the nuclear level for AB and OKC compared to AOT (p < 0.0001). In addition, significant positive correlations were found between cytoplasmic and nuclear GLI-1 in AB (r = 0.482; p = 0.031) and OKC (r = 0.865; p < 0.0001), and between membrane/cytoplasmic SMO and cytoplasmic GLI-1 in AOT (r = 0.667; p = 0.035) and OKC (r = 0.535; p = 0.015). The results of this study confirm the participation of the sonic hedgehog signaling pathway in the pathogenesis of the lesions studied. Overexpression of SHH in ABs and nuclear expression of GLI-1 in ABs and OKCs indicate that these proteins contribute to the more aggressive behavior of these two lesions when compared to AOT.","PeriodicalId":9211,"journal":{"name":"Brazilian dental journal","volume":"33 1","pages":"91 - 99"},"PeriodicalIF":0.0,"publicationDate":"2022-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43430469","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Exposure to lipopolysaccharide and calcium silicate-based materials affects the behavior of dental pulp cells. 暴露于脂多糖和硅酸钙基材料会影响牙髓细胞的行为。
Brazilian dental journal Pub Date : 2022-09-01 DOI: 10.1590/0103-6440202204990
Marlus da Silva Pedrosa, Handially Dos Santos Vilela, Juliana Garuba Rahhal, Natália Pieretti Bueno, Fabianne Soares Lima, Fernando Neves Nogueira, Carla Renata Sipert
{"title":"Exposure to lipopolysaccharide and calcium silicate-based materials affects the behavior of dental pulp cells.","authors":"Marlus da Silva Pedrosa,&nbsp;Handially Dos Santos Vilela,&nbsp;Juliana Garuba Rahhal,&nbsp;Natália Pieretti Bueno,&nbsp;Fabianne Soares Lima,&nbsp;Fernando Neves Nogueira,&nbsp;Carla Renata Sipert","doi":"10.1590/0103-6440202204990","DOIUrl":"https://doi.org/10.1590/0103-6440202204990","url":null,"abstract":"<p><p>This study assessed the cell viability, cytokine production, and mineralization potential of human dental pulp cells (hDPCs) after exposure to lipopolysaccharide (LPS) and application of calcium silicate-based materials (CSBM). Characterization of the CSBM was performed by infrared spectroscopy (n = 3). Extracts of Bio-C Repair, Biodentine, Cimmo HD, and MTA Repair HP were prepared and diluted (1:1, 1:4, and 1:16). Culture of hDPCs was established and treated or not with 1 µg/mL of LPS from Escherichia coli for 7 days. MTT assay was used to assess cell viability at 24, 48, and 72 h (n = 6). Alkaline phosphatase (ALP) activity was assayed on day 7 (n = 4). Il-10 and TNF-α were quantified by ELISA at 24 h (n = 6). Data were analyzed by ANOVA and Tukey's test (α = 0.05). Cell viability of LPS-activated hPDCs was higher than untreated control in 48 and 72 h (p < 0.05). Differences between non-treated and LPS-activated hPDCs were observed for Biodentine and Cimmo HP (p < 0.05). The CSBM influenced the cell viability (p < 0.05). ALP activity was higher in LPS-activated hDPCs (p < 0.05). No changes in the concentration of TNF-α were observed between groups (p > 0.05). The CSBM increased the Il-10 production (p < 0.05). LPS-activated hDPCs presented increased cell viability and ALP activity. The CSBM showed mild toxicity and was able to enhance the cell viability and mineralization potential of untreated and LPS-activated hDPCs. The CSBM also induced anti-inflammatory mechanisms without compromising pro-inflammatory ones.</p>","PeriodicalId":9211,"journal":{"name":"Brazilian dental journal","volume":"33 5","pages":"9-17"},"PeriodicalIF":0.0,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9645168/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10450050","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Profile of brazilian research productivity grant holders with a background in pediatric dentistry. 具有儿童牙科背景的巴西科研生产率补助金获得者简介。
Brazilian dental journal Pub Date : 2022-09-01 DOI: 10.1590/0103-6440202205016
Larissa Chaves Morais de Lima, Veruska Medeiros Martins Bernardino, Isolda Mirelle de Lima Ferreira Prata, Roanny Torres Lopes, Samara Ellen da Silva, Myrelle Leal Campos Sousa, Matheus França Perazzo, Saul Martins Paiva, Ana Flavia Graville-Garcia
{"title":"Profile of brazilian research productivity grant holders with a background in pediatric dentistry.","authors":"Larissa Chaves Morais de Lima, Veruska Medeiros Martins Bernardino, Isolda Mirelle de Lima Ferreira Prata, Roanny Torres Lopes, Samara Ellen da Silva, Myrelle Leal Campos Sousa, Matheus França Perazzo, Saul Martins Paiva, Ana Flavia Graville-Garcia","doi":"10.1590/0103-6440202205016","DOIUrl":"10.1590/0103-6440202205016","url":null,"abstract":"<p><p>This study outlines the profile of research productivity grant holders of the Conselho Nacional de Desenvolvimento Científico e Tecnológico [CNPq (National Council for Scientific and Technological Development)] in the field of pediatric dentistry. A cross-sectional study with data collected from the Brazilian academic curriculum vitae database. The eligibility criterion was being a research productivity grant holder in pediatric dentistry from 2018 to 2020. In the period of interest, 215 individuals were research productivity grant holders in the field of dentistry, 33 of whom had graduate degrees (specialization, master's or doctorate) in pediatric dentistry. The period of scientific production and work concluded of advising of scientific initiation, master, doctoral and post-doctoral degrees was 2010 to 2020. Descriptive analysis was performed and the Kruskal-Wallis test was used to analyze associations (5% significance level) between productivity grant level (2, 1D, 1C, 1B or 1A) and year of obtainment of the doctoral degree. The VOSviewer (version 1.6.17) was used to present graphically the interinstitutional collaborations. The sample was composed of Level 2 researchers (66.7%), women (66.7%), researchers linked to institutions in the southeastern region of Brazil (81.8%), with a doctoral degree concluded prior to 2002 (51.5%), began working as a professor at a higher education institution prior to 2007 (78.8%) and the title of full professor (45.5%). No significant association was found between productivity grant level and year of conclusion of the doctoral degree (p = 0.10). Median (interquartile range) of scientific articles was 119 (37-312). The prevalence of citations (57.52%) and JCR articles (62.76%) was higher among female researchers. In conclusion, CNPq research productivity grant holders in pediatric dentistry are essentially represented by females from the southeast region of the country (UFMG and USP). However, males have proportionally greater productivity.</p>","PeriodicalId":9211,"journal":{"name":"Brazilian dental journal","volume":"33 5","pages":"46-54"},"PeriodicalIF":0.0,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9645172/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10002399","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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