International journal of bioorganic chemistry & molecular biology最新文献_第2页

Assessment of the Levels and Potential Health Risk Posed by Selected Organophosphate Pesticide Residues in Vegetable Farms in Manzini Region, Eswatini 斯瓦蒂尼曼齐尼地区蔬菜农场中部分有机磷农药残留水平及潜在健康风险评估

International journal of bioorganic chemistry & molecular biology Pub Date : 2019-05-06 DOI: 10.11648/J.IJBC.20190401.18

G. Bwembya, P. Junior, J. M. Thwala, Sipho Samuel Mamba, Tesfamariam Y. Debessai, Nomfundo Dlamini

{"title":"Assessment of the Levels and Potential Health Risk Posed by Selected Organophosphate Pesticide Residues in Vegetable Farms in Manzini Region, Eswatini","authors":"G. Bwembya, P. Junior, J. M. Thwala, Sipho Samuel Mamba, Tesfamariam Y. Debessai, Nomfundo Dlamini","doi":"10.11648/J.IJBC.20190401.18","DOIUrl":"https://doi.org/10.11648/J.IJBC.20190401.18","url":null,"abstract":"The study investigated qualitatively and quantitatively the presence of organophosphate pesticide (OPP) residues in cabbages, tomatoes and soil from vegetable gardens of Manzini region and assessed the health risk to consumers. Samples were analysed using QuEChERS extraction technique and GC-ECD. Mean recoveries of the pesticides range from 70.61% to 103.76%. Among 26 samples of cabbages analysed, 8 samples (30.77%) contained residues of dichlorvos with a mean concentration of 2.889 ± 0.617 mg/kg, 8 samples (30.77%) contained residues of dimethoate with mean concentration of 2.898 ± 0.894 mg/kg while 5 samples (19.23%) contained both dichlorvos and dimethoate. The highest concentration of dichlorvos of 5.460 ± 0.911 mg/kg was found in Ngwempisi cabbages while the lowest concentration of 0.415 mg/kg was in Mgazini cabbages. The highest amount of dimethoate of 13.150 ± 3.246 mg/kg was in Matfunjwa cabbages while the lowest amount of dimethoate of 0.106 ± 0.187 mg/kg was in Boyane cabbages. All the contaminated cabbages had residue levels above the Codex (FAO/WHO) and EU MRLs. None of the 15 samples of tomatoes was found to be contaminated with organophosphate pesticides. Out of 41 samples of soil, chlorpyrifos was detected in only 3 samples (7.32%) with mean concentration of 1.145 ± 0.136 mg/kg. The highest amount of 2.778 ± 0.134 mg/kg was found in soil from Buoyane. The health risk estimate also demonstrated that the levels of pesticides residues in cabbages pose health threat to consumers. The results of this study provide a database on the levels of organophosphate pesticide residues in vegetables in the Manzini region to the Ministries of Agriculture and Health. This will help introduce safer pesticide management practices. It will also bring awareness to the general public on the dangers of OPPs to human health and environment.","PeriodicalId":92048,"journal":{"name":"International journal of bioorganic chemistry & molecular biology","volume":"86 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-05-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80615235","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Influence of Arbuscular Mycorrhizal Fungi (AMF) Inoculation on Growth and Mycorrhizal Dependency of (Lens culinaris L.) Varieties 丛枝菌根真菌(AMF)接种对水杨花生长及菌根依赖性的影响品种

International journal of bioorganic chemistry & molecular biology Pub Date : 2019-04-22 DOI: 10.11648/J.IJBC.20190401.17

S. Khan, Tabassum Yaseen, F. Naz, S. Abidullah, M. Kamil

引用次数: 7

Aflatoxin Contamination Level of Different Crops in Ethiopia 埃塞俄比亚不同作物的黄曲霉毒素污染水平

International journal of bioorganic chemistry & molecular biology Pub Date : 2019-04-19 DOI: 10.11648/J.IJBC.20190401.16

Aserse Yenasew

{"title":"Aflatoxin Contamination Level of Different Crops in Ethiopia","authors":"Aserse Yenasew","doi":"10.11648/J.IJBC.20190401.16","DOIUrl":"https://doi.org/10.11648/J.IJBC.20190401.16","url":null,"abstract":"This review paper was conducted to show the current status of aflatoxin contamination level of some selected crop commodities. Different data sources were collected from January, 2018 up to February, 2019 from published, unpublished and other scientific research reports. The results reported by different authors indicated that total aflatoxin, AFB1, AFB2, AFG1 and AFG2 are the aflatoxin types that contaminate groundnut, red pepper, maize, malt barely, sorghum and other types of crop commodities. According to different authors and research reports showed AFB1 is the most common aflatoxin type that contaminates different crops. Based on the review, the current aflatoxin contamination level of some Ethiopian crops were above permissible level according to the FAO/WHO and EU standards. This indicates that most Ethiopia people consume different crops that contaminated by aflatoxin due to lack of awareness about the cause and the effects of aflatoxin. The increment of temperature and moisture content were favorable for the growth of aflatoxigenic fungi. Different authors reported that the moisture and temperature increases, the aflatoxin contamination level of crops also increases.","PeriodicalId":92048,"journal":{"name":"International journal of bioorganic chemistry & molecular biology","volume":"87 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-04-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76729424","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Phytochemical Study and Protective effect of Diospyros lotus Against Carbon Tetrachloride-Induced Hepato and Nephro-Toxicity in Rats 荷花对四氯化碳致大鼠肝、肾毒性的植物化学研究及保护作用

International journal of bioorganic chemistry & molecular biology Pub Date : 2019-03-30 DOI: 10.11648/J.IJBC.20190401.14

G. F. A. Raoof, K. Mohamed, E. Waked, H. Gomaa

{"title":"Phytochemical Study and Protective effect of Diospyros lotus Against Carbon Tetrachloride-Induced Hepato and Nephro-Toxicity in Rats","authors":"G. F. A. Raoof, K. Mohamed, E. Waked, H. Gomaa","doi":"10.11648/J.IJBC.20190401.14","DOIUrl":"https://doi.org/10.11648/J.IJBC.20190401.14","url":null,"abstract":"The present work was carried out to studytheprotective effect of 70% methanolic extract of Diospyros lotus L. aerial parts against hepato and nephro-toxicity that was induced bycarbon tetrachloride. In addition, phytochemical screening, total phenolic, total ﬂavonoid contents and proximate analysisof the aerial parts were determined. Methanol (70%) extracts of the aerial parts of Diospyros lotus L. was prepared. Two main groups of rats were assigned which were normal and damaged liver groups that administrated CCl4 (carbon tetra chloride). Each group classified into 4 different groups normalcontrol: was received distilled water, positive control: was administered silymarin (50 mg/kg), and treated groups:were administered Diospyros lotus tested extract at two dose levels (150 and 300 mg/kg) for 15 days. Serum alanine and aspartate aminotransferase activities were determined to evaluate hepatoprptective effect, while uric acid and creatinine levels were measured to study renal function protective effects. The results showed that the alterations induced by carbon tetrachloride were signiﬁcantly restored by methanol extract of Diospyros lotus (150 and 300 mg/kg) in dose dependant manner. Alkaloids, carbohydrates, tannins, ﬂavonoids, saponins and unsaturated sterols and/or triterpenes were detected as the main active constituents of the methanol extract. It can be concluded that the 70% methanol extract of Diospyros lotus L. aerial parts has a significant protective effect against acute hepato-toxicity and nephro-toxicity induced by CCl4 in ratsso it can be used as a safe hepato-nephro protective drug.","PeriodicalId":92048,"journal":{"name":"International journal of bioorganic chemistry & molecular biology","volume":"20 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-03-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81822138","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Photocatalytic Activity of Zr Doped ZnO and Its Morphology Zr掺杂ZnO的光催化活性及其形貌

International journal of bioorganic chemistry & molecular biology Pub Date : 2019-03-30 DOI: 10.11648/J.IJBC.20190401.13

A. Vijayabalan, A. Sivakumar, Nadarajan Suresh Babu, A. Amalorpavadoss

引用次数: 3

Prodrug Approach: An Alternative to Improve Pharmacokinetic Properties 前药方法:改善药代动力学特性的一种替代方法

International journal of bioorganic chemistry & molecular biology Pub Date : 2019-03-28 DOI: 10.11648/J.IJBC.20190401.12

A. Dhingra, B. Chopra, R. Dass

引用次数: 4

Varietal Advances of Jute, Kenaf and Mesta Crops in Bangladesh: A Review 孟加拉国黄麻、红麻和梅斯塔作物品种进展综述

International journal of bioorganic chemistry & molecular biology Pub Date : 2019-01-01 DOI: 10.11648/j.ijbc.20190401.15

Md Mahbubul Islam

引用次数: 1

Chemical Preparation of Iron Oxide Nanoparticles Using Plants Extracts in Antibacterial Application 植物提取物化学制备纳米氧化铁的抗菌研究

International journal of bioorganic chemistry & molecular biology Pub Date : 2019-01-01 DOI: 10.11648/j.ijbc.20190401.11

Wisam Jafer Aziz, Aliyaa Abd Urabe

引用次数: 1

Biodiesel Potentials and Lubricating Properties of Citrus sinensis Seed Oil 柑桔籽油的生物柴油潜力及润滑性能

International journal of bioorganic chemistry & molecular biology Pub Date : 2019-01-01 DOI: 10.11648/j.ijbc.20190402.11

John Adekunle Oyedele Oyekunle, Saheed Eluwale Elugoke, Abolanle Saheed Adekunle, Oluwaseyi Samson Ojo, Adeniyi Jide Oyinloye, Omowumi Temitope Fakoya, Olaoluwa Ruth Obisesan, Solomon Sunday Durodola

引用次数: 0

Identification of Berenil Target Sites in Plasmid pBR322. 鉴定质粒 pBR322 中的贝瑞尼尔靶位点。

International journal of bioorganic chemistry & molecular biology Pub Date : 2017-01-01 Epub Date: 2017-05-11 DOI: 10.19070/2332-2756-170004

M S Valenzuela, N Green, S Liu

{"title":"Identification of Berenil Target Sites in Plasmid pBR322.","authors":"M S Valenzuela, N Green, S Liu","doi":"10.19070/2332-2756-170004","DOIUrl":"10.19070/2332-2756-170004","url":null,"abstract":"<p><p>Berenil, a minor groove DNA binding molecule, has been extensively used in veterinary medicine. Modeling studies have suggested that berenil binds to A/T rich regions on the DNA and the product of this interaction causes the formation of crosslinks between opposite DNA strands. These crosslinks could potentially inhibit fundamental biological processes including transcription and DNA replication. We had previously used the pBR322 genome as a model system to investigate the role of A/T sequences on berenil activity. We reported that the insertion of poly(dA)poly(dT) sequences into the pBR322 genome causes replication inhibition of the recombinant plasmids when cultures were exposed to berenil. However, we noticed that even in the absence of these sequences the parental plasmid replication was also inhibited, albeit less than the recombinants. This observation led us to the present study were we attempted to identify the location of natural berenil target sites in the pBR322 genome. Through a combination of deletion analysis, recombinant DNA and a replication assay we uncovered a 378 bp DNA fragment that has all the hallmarks of a berenil target site. A recombinant plasmid lacking this region is more refractive to the drug than the parental plasmid, and another variant containing and extra copy of this region increases the susceptibility of the plasmid towards berenil. The 378 bp region is about 60% A/T rich and contains about 21 potential berenil binding sites.</p>","PeriodicalId":92048,"journal":{"name":"International journal of bioorganic chemistry & molecular biology","volume":"5 1","pages":"24-30"},"PeriodicalIF":0.0,"publicationDate":"2017-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5667686/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35523889","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0