BMC Anesthesiology最新文献

{"title":"Incidence and predictors of perioperative mortality in Ethiopia: a systematic review and meta-analysis.","authors":"Tikuneh Yetneberk, Diriba Teshome, Abebe Tiruneh, Yohannes A Dersesh, Nega Getachew, Moges Gelaw, Meseret Firde","doi":"10.1186/s12871-025-03093-z","DOIUrl":"https://doi.org/10.1186/s12871-025-03093-z","url":null,"abstract":"<p><strong>Introduction: </strong>The Lancet Commission on Global Surgery highlights perioperative mortality rate (POMR) as a key indicator of a nation's surgical system effectiveness. While POMR is often measured in high-income countries, it is less studied in low- and middle-income countries (LMICs). This study aims to assess the POMR and its predictors in Ethiopia.</p><p><strong>Methods: </strong>We conducted a thorough literature search across PubMed/MEDLINE, Embase, Web of Science, Scopus, and Google Scholar for studies from Ethiopia between 2019 and 2023 reporting POMR for various surgical procedures. Data were extracted in duplicate from eligible studies. We used random-effects meta-analysis to pool estimates of POMR and its predictors.</p><p><strong>Results: </strong>The meta-analysis revealed a POMR of 5.36%. Identified predictors of perioperative mortality in Ethiopia included older age, comorbidities, ICU admission, and an ASA physical status classification of III or higher and emergency surgeries.</p><p><strong>Conclusion: </strong>Ethiopia's perioperative mortality rate is significantly high. Improving surgical care quality and safety, along with expanding access to surgical services, is crucial for bettering surgical outcomes in the country.</p>","PeriodicalId":9190,"journal":{"name":"BMC Anesthesiology","volume":"25 1","pages":"214"},"PeriodicalIF":2.3,"publicationDate":"2025-04-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12034119/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143976887","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effectiveness of ultrasound-guided versus anatomical landmark-guided percutaneous dilatational tracheostomy: a systematic review and meta-analysis.","authors":"Dan Wen, Xiuru Yang, Zhenghua Liang, Yang Hu, Simei Wang, Dan Zhang, Yao Wang, Yuqi Shen, Fenglin Yan","doi":"10.1186/s12871-025-03085-z","DOIUrl":"https://doi.org/10.1186/s12871-025-03085-z","url":null,"abstract":"<p><strong>Background: </strong>Percutaneous dilatational tracheostomy (PDT) is increasingly used in intensive care units owing to its advantages of reduced surgical trauma and fewer complications. Recently, ultrasonography has become a potentially useful tool for assisting PDT.</p><p><strong>Objective: </strong>To compare ultrasound- and landmark-guided PDT for major bleeding, first-puncture success rates, periprocedural complications, and tracheotomy procedure times.</p><p><strong>Methods: </strong>Randomized controlled trials (RCTs) or non-RCTs comparing ultrasound- and landmark-guided PDT were searched for in PubMed, Web of Science, MEDLINE, CINAHL, Cochrane Library, Wanfang Data Knowledge Service Platform, China National Knowledge Infrastructure (CNKI) and the Chinese Biomedical Literature Service System (SinoMed). The primary outcomes were major bleeding and first puncture success rate. Secondary outcomes were periprocedural complications and the tracheotomy procedure time. The meta-analysis was performed using RevMan 5.3 software.</p><p><strong>Results: </strong>This meta-analysis included five RCTs and one non-RCT, with a total of 609 patients. Compared with landmark-guided PDT, ultrasound-guided PDT can reduce the incidence of major bleeding (odds ratio [OR] = 0.35, 95% confidence interval [CI; 0.14, 0.90], P = 0.03) and improved the success rate of first puncture (OR = 4.41, 95% CI [2.54, 7.65], P < 0.000001). Additionally, ultrasound-guided PDT is associated with a lower incidence of periprocedural complications (OR = 0.35, 95% CI [0.22, 0.54], P < 0.00001). However, there was no advantage in reducing the tracheotomy procedure time between the two methods (mean difference = - 0.64, 95% CI [-4.14, 2.85], P = 0.72).</p><p><strong>Conclusion: </strong>Compared to landmark-guided PDT, ultrasound-guided PDT can reduce the incidence of major bleeding and periprocedural complications and increase the success rate of the first puncture. However, the advantage of ultrasound-guided PDT in reducing the tracheotomy procedure time is unclear.</p>","PeriodicalId":9190,"journal":{"name":"BMC Anesthesiology","volume":"25 1","pages":"211"},"PeriodicalIF":2.3,"publicationDate":"2025-04-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12023463/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143973281","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Etomidate-Induced myoclonus in Sprague‒Dawley rats involves the activation of neocortical Calpain-2 and its decrement on KCC2 protein.","authors":"Yan Feng, Yong-Xiang Cheng, Xing-Hao Wang","doi":"10.1186/s12871-025-03065-3","DOIUrl":"https://doi.org/10.1186/s12871-025-03065-3","url":null,"abstract":"<p><strong>Background: </strong>Etomidate-induced myoclonus has become a pressing clinical problem with an incidence of 50-80%. The underlying mechanism involves neocortical glutamate accumulation and N-methyl-d-aspartate (NMDA) receptor activity. However, the therapeutic target remains uncertain.</p><p><strong>Methods: </strong>Adult male Sprague-Dawley (SD) rats were injected with etomidate (1.5 mg/kg), propofol (11.8 mg/kg), and lidocaine (4.0 mg/kg) plus etomidate (1.5 mg/kg), etomidate (3.8 mg/kg), etomidate (6.0 mg/kg) through the tail vein and behavioral scores of the rats were recorded within 5 min after anesthesia to establish the model of etomidate-induced myoclonus and to observe the dose dependence. The in vitro Western blot analysis of NKCC1 and KCC2 proteins and the regulatory effect of N-methyl-d-aspartate (NMDA) receptor were performed to find the potential target of etomidate-induced myoclonus or excitability. Additionally, to verify whether calpain-2 is involved in the process of regulatory effect of NMDAR on the cleavage of KCC2 protein during etomidate-induced myoclonus, muscular tension and KCC2 protein were analyzed in rats microinjected with calpain-2 inhibitor (MDL-28170) or MDL-28170 + NMDA in the neocortical motor cortex during etomidate anesthesia. Finally, MDL-28170 or vitamin E was injected intravenously before etomidate, the muscular tension, KCC2 protein and duration of loss of righting reflex (LORR) of rats were evaluated to verify the neuroprotective effect of vitamin E.</p><p><strong>Results: </strong>Etomidate significantly increased the mean behavioral score at different time points compared with the propofol and lidocaine + etomidate groups within 5 min after anesthesia; the mean behavioral score decreased at different time points with increasing dose of etomidate. 0.5 µM ( 0.73 ± 0.18 vs. 1.04 ± 0.17, n = 6, p = 0.0096) and 1 µM (0.73 ± 0.24 vs. 1.03 ± 0.14, n = 6, p = 0.0077) etomidate induced the decrement of neocortical KCC2 protein compared to the control group. NMDA activated but 2-amino-5-phosphonopentanoic acid (AP5) inhibited 0.5 and 1 µM etomidate-induced decrement of neocortical KCC2 protein. MDL-28170 microinjected into the neocortex during etomidate anesthesia not only inhibited the decrement of KCC2 protein but also blocked the muscular tension induced by etomidate alone or etomidate plus NMDA. Intravenous injection of vitamin E prevented etomidate-induced muscular tension and decrement of the KCC2 protein.</p><p><strong>Conclusion: </strong>Calpain-2 was involved in the process of etomidate-induced myoclonus and NMDAR activity by promoting the decrement of KCC2 protein and exerting the excitability. Vitamin E, as a natural antioxidant, can effectively prevent etomidate-induced myoclonus and does not affect recovery after etomidate anesthesia in rats.</p>","PeriodicalId":9190,"journal":{"name":"BMC Anesthesiology","volume":"25 1","pages":"213"},"PeriodicalIF":2.3,"publicationDate":"2025-04-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12023595/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143985919","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A comparison of McGrath MAC, AIRWAY SCOPE^®, and AceScope^® video laryngoscopes in novice healthcare providers: a randomized crossover simulation study.","authors":"Musashi Yahagi, Kyuma Omi, Yuichi Yaguchi","doi":"10.1186/s12871-025-03094-y","DOIUrl":"https://doi.org/10.1186/s12871-025-03094-y","url":null,"abstract":"<p><strong>Background: </strong>Video laryngoscopes are widely used for tracheal intubation, particularly in challenging airway scenarios. The McGrath MAC, AIRWAY SCOPE^®, and AceScope^® are popular video laryngoscopes with different design features. This study aimed to compare the effectiveness and usability of these three devices in novice healthcare providers during simulated tracheal intubation scenarios employing a manikin.</p><p><strong>Methods: </strong>Sixty novice healthcare providers, including nurses and pharmacists, were enrolled in this randomized crossover study. Participants performed tracheal intubation using the McGrath MAC, AIRWAY SCOPE, and AceScope in both normal airway and cervical spine immobilization models. Primary outcomes were intubation success rate and time to intubation. Secondary outcomes included user preferences, device ease of use, and the incidence of dental injuries.</p><p><strong>Results: </strong>The AIRWAY SCOPE demonstrated the shortest intubation time in both normal airway and cervical spine immobilization models (14.90 ± 1.76 s and 23.80 ± 2.43 s, respectively), followed by the McGrath MAC and AceScope. All devices exhibited high success rates, and there were no significant differences in perceived difficulty among the three video laryngoscopes. The incidence of dental injuries was generally comparable among the devices. However, in the cervical spine immobilization model, the AceScope demonstrated a significantly higher rate of dental injuries compared to the McGrath MAC (p < 0.05), highlighting a potential concern for clinical practice.</p><p><strong>Conclusions: </strong>The AIRWAY SCOPE was the most efficient video laryngoscope in terms of intubation time, followed by the McGrath MAC and AceScope. However, all devices showed high success rates and no significant differences in perceived difficulty. Further research is needed to validate these findings in clinical settings and investigate the impact of device-specific features on intubation outcomes and dental injury incidence.</p><p><strong>Trial registration: </strong>Registration number: jRCT1030240598 ( https://jrct.niph.go.jp/re/reports/detail/91422 ) The registration date of the clinical trial is January 8, 2025.UMIN000050394.</p>","PeriodicalId":9190,"journal":{"name":"BMC Anesthesiology","volume":"25 1","pages":"212"},"PeriodicalIF":2.3,"publicationDate":"2025-04-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12023392/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143972743","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Family members' experiences with intensive care unit diaries.","authors":"Vincenzo Bosco, Caterina Mercuri, Rita Nocerino, Michał Czapla, Izabella Uchmanowicz, Rocco Mazzotta, Vincenza Giordano, Silvio Simeone","doi":"10.1186/s12871-025-03083-1","DOIUrl":"https://doi.org/10.1186/s12871-025-03083-1","url":null,"abstract":"<p><strong>Background: </strong>The admission of a family member to intensive care represents an emotionally complex experience, often characterised by anxiety, stress and uncertainty. ICU diaries, compiled by nurses and family members, have been proposed as a useful tool to support caregivers' psychological well-being, improve communication and humanise the care environment. The aim of the study was to describe the content of ICU diaries filled out by family members to explore the experiences and meanings attributed to the diaries.</p><p><strong>Methods: </strong>The study used a qualitative approach based on thematic analysis of diaries completed by 16 family members of patients admitted to intensive care units. The data were coded and analysed to identify recurrent themes and to understand the emotional and psychological experience of the family members.</p><p><strong>Results: </strong>Three main themes emerged from the analysis: time, the family context (including maintaining contact with the patient, the relatives'emotions, fear of suffering, spirituality, the person at the centre of the relatives' lives and connection with the outside world) and the usefulness of the diary in understanding the care process. The diaries facilitated the continuity of the affective bond with the patient, offered a space to express emotions and improved communication with healthcare professionals.</p><p><strong>Conclusion: </strong>The results highlight the value of ICU diaries in supporting family members during the patient's admission, reducing stress and strengthening the relationship with the healthcare team. The practical implications suggest the importance of promoting the structured use of diaries to foster more empathetic and family-centred care.</p><p><strong>Clinical trial number: </strong>Not applicable.</p>","PeriodicalId":9190,"journal":{"name":"BMC Anesthesiology","volume":"25 1","pages":"210"},"PeriodicalIF":2.3,"publicationDate":"2025-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12023576/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143963384","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of serratus posterior superior intercostal plane block on postoperative analgesia in patients undergoing breast cancer surgery: a randomized controlled trial.","authors":"Bengü G Köksal, Çağdaş Baytar, Emine Bayraktar, Hakan Balbaloğlu","doi":"10.1186/s12871-025-03092-0","DOIUrl":"10.1186/s12871-025-03092-0","url":null,"abstract":"<p><strong>Background: </strong>The serratus posterior superior intercostal plane block (SPSIPB) is a newly described truncal block. This study aimed to compare the effects of SPSIPB with conventional methods on postoperative opioid consumption and pain scores within 24 h postoperatively.</p><p><strong>Methods: </strong>This randomized controlled trial included 60 patients aged 18-65 years with an American Society of Anesthesiologists Physical Status of I-III. Patients were randomly assigned to either the SPSIPB or the control group. The primary outcome was cumulative opioid consumption within the first 24 h postoperatively. Secondary outcomes included resting and dynamic Numerical Rating Scale (NRS) pain scores, Quality of Recovery (QoR)-15 questionnaire scores, intraoperative remifentanil consumption, and the incidence of postoperative nausea and vomiting.</p><p><strong>Results: </strong>Total tramadol consumption was significantly lower in the SPSIPB group during the first 12 h and at the end of the 24th hour postoperatively compared with the control group (p < 0.05). The dynamic NRS score at 0 h postoperatively was lower in the SPSIPB group (p = 0.001), whereas no significant differences in NRS scores were observed at other time-points. The postoperative QoR-15 scores were significantly higher in the SPSIPB group compared with the control group. Furthermore, the SPSIPB group had significantly lower intraoperative remifentanil consumption (p = 0.003). Nausea and vomiting were more frequent at 12 and 24 h postoperatively in the control group compared with the SPSIPB group.</p><p><strong>Conclusions: </strong>Serratus posterior superior intercostal plane block significantly reduced opioid use, and improved recovery quality after oncoplastic breast surgery.</p><p><strong>Trial registration: </strong>NCT06225908, registered at ClinicalTrials.gov.</p>","PeriodicalId":9190,"journal":{"name":"BMC Anesthesiology","volume":"25 1","pages":"209"},"PeriodicalIF":2.3,"publicationDate":"2025-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12020093/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143974981","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Dexamethasone as an additive to bupivacaine in an ultrasound-guided adductor canal block for the management of persistent pain after arthroscopic reconstruction of the anterior cruciate ligament: a randomized, double-blind study.","authors":"Saeid Elsawy, Amani Abdelwahab, Yara Hamdi, Rasha Ahmed Ali Hamed","doi":"10.1186/s12871-025-02921-6","DOIUrl":"https://doi.org/10.1186/s12871-025-02921-6","url":null,"abstract":"<p><strong>Background: </strong>Pain is a protective response to noxious stimuli to prevent further damage. The surgical incision results in several events that lead to pain that outlasts its benefits. Persistent postsurgical pain (PPSP) is defined as \"pain that persists for three months after surgical intervention.</p><p><strong>Objectives: </strong>To investigate the effect of dexamethasone as an adjuvant to adductor canal block on persistent postsurgical pain after ACL reconstruction.</p><p><strong>Patients and methods: </strong>Ninety patients who underwent arthroscopic reconstruction of the anterior cruciate ligament and who completed the study were randomly allocated into two groups. Forty-five patients in each group received ultrasound-guided adductor canal block at the end of surgery. G I (Dexa group): Forty-five patients received a 20 ml mixture of 0.25% bupivacaine and 8 mg dexamethasone (2 ml). G II (control group): Patients received a 20 ml mixture of 0.25% bupivacaine and 2 ml of normal saline.</p><p><strong>Results: </strong>No significant differences in demographic data, intraoperative hemodynamics or surgery duration were detected between the two groups. The duration of postoperative analgesia was significantly longer in the dexamethasone group (10 h ± 3 vs. 6 h ± 1) than in the control group. Additionally, 24 h postoperative consumption of meperidine was significantly lower in the dexamethasone group (65 ± 23 vs. 104 ± 27) than in the control group. Postoperative VAS scores at 6 and 12 h were also lower in the dexamethasone group than in the control group. Three-month follow-up revealed a significantly lower incidence of PPSP in the dexamethasone group (20% versus 33% in the control group). Moreover, the severity of PPSP was significantly lower in the dexamethasone group than in the control group. Additionally, Codeine consumption was significantly lower in the dexamethasone group than in the control group.</p><p><strong>Conclusion: </strong>Perineural dexamethasone in ultrasound-guided adductor canal block reduced the severity of PPSP and opioid analgesia consumption in the first three months following arthroscopic reconstruction of the ACL.</p><p><strong>Clinical trial registration: </strong>The study was registered on clinical trial registration (NCT04631822) in October 2020.</p>","PeriodicalId":9190,"journal":{"name":"BMC Anesthesiology","volume":"25 1","pages":"208"},"PeriodicalIF":2.3,"publicationDate":"2025-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12020280/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143979256","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Optimizing pediatric preoperative fasting management: a survey of practices and real durations in Chinese hospitals.","authors":"Bin Zhang, Shoudong Pan, Jijian Zheng, Bo Li, Yi Miao, Guohua Liu","doi":"10.1186/s12871-025-03064-4","DOIUrl":"https://doi.org/10.1186/s12871-025-03064-4","url":null,"abstract":"<p><strong>Background: </strong>Rational preoperative fasting can reduce the risk of regurgitation and aspiration, enhance anesthesia safety and efficiency, and mitigate the adverse effects of prolonged fasting. This study investigates the existing practices of preoperative fasting management in Chinese pediatric patients and explores the real duration of preoperative fasting.</p><p><strong>Methods: </strong>This is a cross-sectional study. A questionnaire on fasting management in children was developed and an online survey was conducted among anesthesiologists. The survey mainly included the real implementation of pediatric fasting protocols, anesthesiologists' understanding of pediatric fasting management, and the application of gastric ultrasound. Moreover, data on pediatric preoperative fasting durations were collected from different hospitals across China.</p><p><strong>Results: </strong>A total of 770 questionnaires and 1285 records of preoperative fasting cases were obtained. The survey indicated variations in preoperative fasting protocols among hospitals. Most hospitals recommended fasting for clear fluids for 2 h, while the new 1-h regimen and the liberal regimen were less implemented due to concerns regarding regurgitation and aspiration risks. Fasting for breast milk, formula milk, and solid food was mainly based on traditional protocols, with fasting durations of 4 h, 6 h, and 8 h, respectively. Most anesthesiologists have experienced regurgitation and aspiration, but there were significant differences in their awareness of the prevention and prognosis of regurgitation and aspiration. Utilization of gastric ultrasound was limited, with a lack of equipment and familiarity among anesthesiologists. Real preoperative fasting durations for children were significantly longer than those recommended in the guidelines. Factors contributing to prolonged fasting were identified.</p><p><strong>Conclusions: </strong>There is a big gap between preoperative fasting practices and the guidelines, and the real fasting durations of children before surgery are significantly longer than the guideline recommendations. Anesthesiologists should strengthen their understanding of preoperative fasting management in pediatric patients, master the skills of gastric ultrasound assessment, and timely address inefficiencies in pediatric preoperative fasting management.</p>","PeriodicalId":9190,"journal":{"name":"BMC Anesthesiology","volume":"25 1","pages":"204"},"PeriodicalIF":2.3,"publicationDate":"2025-04-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12016447/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143983423","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Validation of the Thai version of the quality of recovery scale (QoR-14-Thai) after elective abdominal surgery under general anesthesia.","authors":"Lalisa Saeaeh, Pornprom Sitthivethayanont, Theerawat Chalacheewa, Tharin Thampongsa, Chakrit Sukying, Rojnarin Komonhirun, Lisa Sangkum","doi":"10.1186/s12871-025-03044-8","DOIUrl":"https://doi.org/10.1186/s12871-025-03044-8","url":null,"abstract":"<p><strong>Background: </strong>The 15-item Quality of Recovery scale (QoR-15), a short form of the QoR-40, is a widely used self-reported tool for measuring the postoperative quality of recovery. It has been translated into many languages. In this study, we aimed to validate a translated Thai version of the QoR-15 in patients undergoing elective abdominal surgery under general anesthesia.</p><p><strong>Methods: </strong>This was a single-center observational cohort study. The QoR-15 was translated into Thai and culturally adapted, which led to the items on severe and moderate pain being merged, yielding a 14-item scale: the QoR-14-Thai. Next, the QoR-14-Thai, a checklist measuring the patients' activities of daily living (ADL), and a 100-mm visual analog scale for assessing their global health (VAS-GH) were administered to the study patients before and 24 h after their abdominal surgery. The validity, reliability, responsiveness, and feasibility of the QoR-14-Thai were assessed.</p><p><strong>Results: </strong>Among 166 patients, 140 completed the questionnaires, achieving a questionnaire completion rate of 100%. We observed moderate convergent validity between the postoperative QoR-14-Thai and the VAS-GH (r = 0.54, p < 0.001) and ADL checklist (r = 0.50, p < 0.001). The QoR-14-Thai was negatively correlated with the length of hospital stay (r = - 0.23, p < 0.006) and postoperative admission to the intensive care unit (r = - 0.85, p = 0.001). The QoR-14-Thai had excellent internal consistency (Cronbach's alpha = 0.869), split-half reliability (0.913), test-retest reliability (0.94), and high responsiveness (Cohen's effect size: 1.01, standardized response mean: 0.73). The median time to complete the questionnaire was 2 min (interquartile range: 1-2).</p><p><strong>Conclusions: </strong>The QoR-14-Thai was deemed a valid, reliable, and convenient tool for evaluating the quality of recovery after elective abdominal surgery.</p><p><strong>Trial registration: </strong>This study was registered prospectively on the Thai Clinical Trials Registry, identifier TCTR20210326009, on March 26, 2021.</p>","PeriodicalId":9190,"journal":{"name":"BMC Anesthesiology","volume":"25 1","pages":"205"},"PeriodicalIF":2.3,"publicationDate":"2025-04-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12016262/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143983425","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Successful sedation with remimazolam and alfentanil in a child susceptible to malignant hyperthermia: a case report.","authors":"Kailai Zhu, Shuangwei Wu, Xianglin Hao, Chuanguang Wang","doi":"10.1186/s12871-025-03076-0","DOIUrl":"https://doi.org/10.1186/s12871-025-03076-0","url":null,"abstract":"<p><strong>Background: </strong>Malignant hyperthermia (MH) is a life-threatening autosomal-dominant disorder caused by mutations in the ryanodine receptor 1 (RYR1) gene, leading to calcium dysregulation in skeletal muscle. Patients with genetically confirmed MH susceptibility must strictly avoid volatile anesthetics and succinylcholine. Intravenous sedation presents a viable alternative, yet evidence supporting remimazolam use in pediatric MH patients remains scarce.</p><p><strong>Case presentation: </strong>We report the first case of a 1-year-old male patient with genetically confirmed MH susceptibility undergoing orchidopexy under remimazolam-alfentanil sedation combined with caudal block. The patient had no MH manifestations intraoperatively or postoperatively and recovered uneventfully.</p><p><strong>Conclusion: </strong>This case demonstrates the feasibility of remimazolam-based sedation in genetically confirmed pediatric MH patients, supporting its safety profile in this population. Further multicenter studies are needed to establish standardized protocols.</p>","PeriodicalId":9190,"journal":{"name":"BMC Anesthesiology","volume":"25 1","pages":"207"},"PeriodicalIF":2.3,"publicationDate":"2025-04-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12016150/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143976492","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}