{"title":"Identifying improvements in an emergency department elder friendly area based on patient experience “ED_EFA their voice project”","authors":"M. Puig, Miriam Mateo, M. Blázquez, J. Ris","doi":"10.15761/ICM.1000150","DOIUrl":"https://doi.org/10.15761/ICM.1000150","url":null,"abstract":"The Emergency Departments (EDs) classically focus on the identification of patients' acute disorders, their diagnosis, treatment and early discharge. However, in older people, urgent care must have particular features to ensure quality [1]. First, it frequently requires simultaneous treatment of several medical, social and functional problems. In addition, the priorities are symptom control, maximizing quality of life, and ensuring the continuum of care. For all these reasons, experts and scientific societies recommend developing strategies in EDs that combine: 1) comprehensive geriatric assessment (CGA); 2) structural customization; and 3) training of professionals in geriatric care [2-5].","PeriodicalId":91880,"journal":{"name":"Integrative clinical medicine","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67469572","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
P. Dhillon, P. Grivas, B. Hobbs, Daniel S Carlson, S. Abraksia
{"title":"Education and informed decision making for prostate cancer screening in a high risk African American community","authors":"P. Dhillon, P. Grivas, B. Hobbs, Daniel S Carlson, S. Abraksia","doi":"10.15761/icm.1000146","DOIUrl":"https://doi.org/10.15761/icm.1000146","url":null,"abstract":"","PeriodicalId":91880,"journal":{"name":"Integrative clinical medicine","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67469317","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Application of silver needle thermal therapy in the chronic pain","authors":"Junmin Yu, Chuansheng Liu, Yanwei Yin, Fenghe Xu, Yusheng Yi, Chao Meng","doi":"10.15761/ICM.1000138","DOIUrl":"https://doi.org/10.15761/ICM.1000138","url":null,"abstract":"Silver needle thermal therapy (SNT) originated in the 1970s. Initially, SNT was created through combining muscle relaxation and acupuncture treatment basing on human soft-tissues anatomy by Prof. Renzhe Xuan, and applied this technique to the treatment of intractable chronic soft-tissues pain. It has been achieved good therapeutic effects. With the development of technology, especially the temperature-controlled silver needle therapy instrument instead of burning cotton ball, SNT technology is further promoted in the clinic, and widely used in the treatment of chronic pain. This is a review about the progress and development of SNT and its application in chronic pain. *Correspondence to: Chao Meng, Department of Pain Management, the Affiliated Hospital of Qingdao University, Qingdao, China, Tel: +86-18661808786, E-mail: mengchao1119@126.com","PeriodicalId":91880,"journal":{"name":"Integrative clinical medicine","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67469414","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Gregory Oxenkrug, Marieke van der Hart, Julien Roeser, Paul Summergrad
{"title":"Peripheral kynurenine-3-monooxygenase deficiency as a potential risk factor for metabolic syndrome in schizophrenia patients.","authors":"Gregory Oxenkrug, Marieke van der Hart, Julien Roeser, Paul Summergrad","doi":"10.15761/ICM.1000105","DOIUrl":"https://doi.org/10.15761/ICM.1000105","url":null,"abstract":"<p><p>Increased predisposition of schizophrenia patients (SP) to development of obesity and insulin resistance suggested common signaling pathway between metabolic syndrome (MetS) and schizophrenia. Deficiency of kynurenine-3-monooxygenase (KMO), enzyme catalyzing formation of 3-hydroxykynurenine (3-HK) from kynurenine (Kyn), a tryptophan (Trp) metabolite, might contribute to development of MetS as suggested by non-expression of KMO genes in human fat tissue and elevated serum concentrations of Kyn and its metabolites, kynurenic (KYNA) and anthranilic (ANA) acids, in diabetic patients and Zucker fatty rats (ZFR). Markers of KMO deficiency: decreased 3-HK and elevated Kyn, KYNA and ANA, were observed in brains and spinal fluids of SP, and in brains and serum of experimental animals with genetically- or pharmacologically-induced KMO deficiency. However, elevated concentrations of ANA and decreased 3-HK were reported in serum of SP without concurrent increase of Kyn and KYNA. Present study aimed to re-assess serum Kyn metabolites (HPLC-MS) in a sub-group of SP with elevated KYNA. We found increased Kyn concentrations (by 30%) and Kyn:Trp ratio (by 20%) in serum of SP with elevated KYNA concentrations (by 40%). Obtained results and our previous data suggest that peripheral KMO deficiency might be manifested by, at least, two different patterns: elevated ANA with decreased 3-HK; and elevated KYNA and KYN. The latter pattern was previously described in type 2 diabetes patients and might underline increased predisposition of SP to development of MetS. Assessment of peripheral KMO deficiency might identify SP predisposed to MetS. Attenuation of the consequences of peripheral KMO deficiency might be a new target for prevention/treatment of obesity and diabetes in SP.</p>","PeriodicalId":91880,"journal":{"name":"Integrative clinical medicine","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2017-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5523985/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35202300","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}