Pediatric dimensions最新文献_第2页

Effectiveness of a bundle to prevent unplanned extubation in a pediatric intensive care unit: A multidisciplinary approach 在儿科重症监护病房预防意外拔管的捆绑措施的有效性:一种多学科方法

Pediatric dimensions Pub Date : 2020-01-01 DOI: 10.15761/PD.1000201

V. Neves, C. G. Ribas, B. Miranda, Elessandra Bitencourt, A. Koliski, M. Cat, J. Carreiro

{"title":"Effectiveness of a bundle to prevent unplanned extubation in a pediatric intensive care unit: A multidisciplinary approach","authors":"V. Neves, C. G. Ribas, B. Miranda, Elessandra Bitencourt, A. Koliski, M. Cat, J. Carreiro","doi":"10.15761/PD.1000201","DOIUrl":"https://doi.org/10.15761/PD.1000201","url":null,"abstract":"Endotracheal intubation is one of the most common invasive procedures in routine pediatric intensive care. Unplanned extubation occurs when an endotracheal tube is inadvertently removed. To observe and report the incidence of unplanned extubation in children before and after the introduction of a series of measures aimed at controlling and reducing this adverse event in a pediatric intensive care unit. In 2016, a total of 312 patients were hospitalized in the pediatric intensive care unit. Of these, 120 received mechanical ventilation and there were 30 unplanned extubations, corresponding to an annual incidence of 4.24%. In 2017, the corresponding figures were 301, 163, 42 and 3.4%. In 2018, after the introduction of measures to control and reduce the number of unplanned extubations, the corresponding figures were 335, 195, 31 and 1.79%. The incidence in 2018 was statistically significantly lower than in 2017 and 2016 (p < 0.01). Systematic control of the incidence of unplanned extubation and the introduction of a bundle of measures led to a significant reduction in this type of extubation in the pediatric intensive care unit.","PeriodicalId":91786,"journal":{"name":"Pediatric dimensions","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67503859","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

The association between vitamin D levels and necrotizing enterocolitis in preterm neonates 维生素D水平与早产儿坏死性小肠结肠炎的关系

Pediatric dimensions Pub Date : 2020-01-01 DOI: 10.15761/PD.1000208

K. Kamrani, M. Mardani, M. Zarkesh

{"title":"The association between vitamin D levels and necrotizing enterocolitis in preterm neonates","authors":"K. Kamrani, M. Mardani, M. Zarkesh","doi":"10.15761/PD.1000208","DOIUrl":"https://doi.org/10.15761/PD.1000208","url":null,"abstract":"Backgroung & purpose: Necrotizing enterocolitis (NEC) with high morbidity and mortality rates is a frequent gastrointestinal disease among preterm infants. This study was conducted to evaluate any relationships between maternal/ neonatal serum vitamin D concentrations and the incidence of necrotizing enterocolitis in preterm newborns. Methods: A prospective case-control study was carried out in an Iranian hospital in 2018. Patients and methods: Thirty-two NICU hospitalized neonates due to NEC and 32 hospitalized neonates due to prematurity with their mothers were considered as the case and control groups. Immediately after delivery, 5 ml of the mother’s blood was collected and sent to the laboratory. Two ml of neonate’s blood was also collected in the time of admission and sent to the laboratory. Our primary objective was to assess the association between maternal/neonatal vitamin D serum concentrations and the risk of NEC. Results: The means of maternal and neonatal serum vitamin D were 35.00 ± 15.94 and 33.29 ± 14.96. There was a significant positive correlation between maternal and neonatal vitamin D status (p=0.0001). There were significant associations between NEC and some neonatal factors including neonate’s low birth weight (p=0.01), head circumference (p=0.02), and height (p=0.03), as well as low Apgar score at first minute (p=0.04). No significant associations were observed between NEC with maternal and neonatal levels of vitamin D status . Conclusion: Our results showed a significant positive correlation between maternal and neonatal vitamin D status. Although some neonatal characteristics were significantly correlated to NEC, this significant association was not observed with maternal/neonatal levels of vitamin D.","PeriodicalId":91786,"journal":{"name":"Pediatric dimensions","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67504377","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

How to support quality of life of children with cancer and their parents? 如何支持癌症儿童及其父母的生活质量？

Pediatric dimensions Pub Date : 2019-07-26 DOI: 10.15761/PD.1000192

C. Grégoire, M. Faymonville, A. Vanhaudenhuyse, C. Chantrain, J. Marini, I. Bragard

引用次数: 0

Toxic metals in cord blood and later development of Type 1 diabetes 脐带血中的有毒金属与1型糖尿病的后期发展

Pediatric dimensions Pub Date : 2019-05-24 DOI: 10.15761/PD.1000186

J. Ludvigsson, P. Andersson-White, C. Guerrero-Bosagna

{"title":"Toxic metals in cord blood and later development of Type 1 diabetes","authors":"J. Ludvigsson, P. Andersson-White, C. Guerrero-Bosagna","doi":"10.15761/PD.1000186","DOIUrl":"https://doi.org/10.15761/PD.1000186","url":null,"abstract":"The incidence of type 1 diabetes (T1D) has increased explained by changes in environment or lifestyle. In modern society dissemination of heavy metals has increased. As the autoimmune process usually starts already, we hypothesized that exposure to toxic metals during fetal life might contribute to development of T1D in children. We analysed arsenic (AS), aluminium (Al), cadmium (Cd), lithium (Li), mercury (Hg), lead (Pb), in cord blood of 20 children who later developed T1D (probands), and in 40 age-and sex-matched controls. Analysis of heavy metals in cord blood was performed by ALS Scandinavia AB (Luleå, Sweden) using the ‘ultrasensitive inductively coupled plasma sector field mass spectrometry method’ (ICP-SFMS) after acid digestion with HNO3. Most children had no increased concentrations of the metals in cord blood. However, children who later developed T1D had more often increased concentrations (above limit of detection; LOD) of aluminium (p = 0.006) in cord blood than the non-diabetic controls, and also more often mercury and arsenic (n.s). Our conclusion is that exposure to toxic metals during pregnancy might be one among several contributing environmental factors to the disease process if confirmed in other birth cohort trials.","PeriodicalId":91786,"journal":{"name":"Pediatric dimensions","volume":"4 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-05-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43897473","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 9

Novel approaches to anesthesia in electroconvulsive therapy 电休克治疗中麻醉的新方法

Pediatric dimensions Pub Date : 2019-01-01 DOI: 10.15761/PD.1000182

Behzad Nazemroaya, A. Pourreza

引用次数: 0

Home oxygen therapy for acute bronchiolitis 急性细支气管炎的家庭氧疗

Pediatric dimensions Pub Date : 2019-01-01 DOI: 10.15761/pd.1000189

Michael Sarrell E

{"title":"Home oxygen therapy for acute bronchiolitis","authors":"Michael Sarrell E","doi":"10.15761/pd.1000189","DOIUrl":"https://doi.org/10.15761/pd.1000189","url":null,"abstract":"Objective: To investigate the utility of home oxygen treatment for acute bronchiolitis in infants. Design: Prospective, randomized, intent-to-treat. Setting: Pediatric tertiary, university-affiliated medical center. Patients: 135 children aged < 12 months who presented to an urban primary pediatric clinic in 2009-2011 with RSV bronchiolitis and mild to moderate hypoxia. Interventions: Random allocation to three groups: Inhaled hypertonic or bronchodilator + supplemental oxygen (2 l/min for 30 min 4 times daily) or bronchodilator only (control). Main outcome measures: Number of emergency department visits and hospitalizations, number of lost days of daycare (infants) and work (parents), parental satisfaction, and changes in signs and symptoms. Results: Background data were similar in all groups. Compared to the control group, oxygen-treated groups were characterized by a significantly shorter interval to normalization of respiratory rate and oxygen saturation (p < 0.001), significantly fewer hospital admissions (p < 0.0001), and emergency department referrals (p < 0.001), a significantly lower rate of chest infiltrates during follow-up (p < 0.0001), and fewer missed days of daycare and work (p < 0.0001). Rates of caregiver satisfaction were 88% and 78% in the oxygen-treated groups and 44% in the control group. Conclusion: The administration of supplementary oxygen treatment at home in children aged < 12 months with RSV bronchiolitis is effective and safe, leading to a reduction in emergency department referrals and hospital admissions and an increase in caregiver satisfaction. *Correspondence to: Michael Sarrell E, 7 Ha’Iris St. Moshav Gan Hayim 44910, Israel, Tel: +972-9-7409610, Cell: +972-544289279; Fax: +972-97403196; E-mail: michaelsar@clalit.org.il","PeriodicalId":91786,"journal":{"name":"Pediatric dimensions","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67503985","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Yerusinia infection with symptoms of Kawasaki disease in Japan 日本与川崎病症状有关的耶氏菌感染

Pediatric dimensions Pub Date : 2019-01-01 DOI: 10.15761/pd.1000187

Y. Tomita

引用次数: 0

Novel biochemical and reliable technique for the rapid detection of extended-spectrum β-lactamase-producing Enterobacterales; the rapid ESBL NP test 产β-内酰胺酶肠杆菌广谱快速检测新技术快速ESBL NP测试

Pediatric dimensions Pub Date : 2019-01-01 DOI: 10.15761/pd.1000197

Mustafa Sadek, L. Poirel, P. Nordmann

{"title":"Novel biochemical and reliable technique for the rapid detection of extended-spectrum β-lactamase-producing Enterobacterales; the rapid ESBL NP test","authors":"Mustafa Sadek, L. Poirel, P. Nordmann","doi":"10.15761/pd.1000197","DOIUrl":"https://doi.org/10.15761/pd.1000197","url":null,"abstract":"Extended-Spectrum β-lactamase-producing Enterobacterales (ESBL-E) constitutes a global burden and is one of the major threats to public health. The production of ESBLs precludes the use of broad-spectrum cephalosporins, making carbapenems the drug of choice for these infections. Thus, the increased prevalence of these organisms has stimulated the empiric use of carbapenems as therapy where ESBL-E are suspected, favoring selection of carbapenem-resistant Enterobacterales. Rapid detection of ESBL-E constitutes a challenge for clinical microbiologists to prevent delaying efficient antibiotic therapy that worsens the survival of the most severely ill patients. Rapid diagnostic tests may identify drug-resistant bacteria, determine antimicrobial susceptibility, and distinguish viral from bacterial infections, therefore guiding effective treatment strategies. Indeed, implementation of strategies for antibiotic stewardship are now required by the Federal government in hospitals across the USA. Rapid diagnostic tests facilitate epidemiological surveillance, by providing the possibility to monitor the transmission of emerging and antibiotic-resistant microorganisms. Traditional techniques for detecting ESBL-PE include phenotypic tests (to detect the presence of the enzyme) or molecular tests (to detect the genes encoding such enzymes). Both current approaches are time-consuming (24-48 h) since they usually require the isolation or growth of the organism before the test is performed. In this review article, we discussed the rapid diagnostic strategies particularly the rapid ESBL test and how such rapid tests can facilitate the surveillance of resistance evolution and guide effective therapeutic strategies. *Correspondence to: Patrice Nordmann, Medical and Molecular Microbiology, Faculty of Science and Medicine, University of Fribourg, Fribourg, Switzerland, Tel: +41 26 300 9581; E-mail: patrice.nordmann@unifr.ch","PeriodicalId":91786,"journal":{"name":"Pediatric dimensions","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67503686","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Bedside lung ultrasound guided the treatment of neonatal respiratory distress syndrome by mechanical ventilation 床边肺超声引导机械通气治疗新生儿呼吸窘迫综合征

Pediatric dimensions Pub Date : 2019-01-01 DOI: 10.15761/pd.1000194

Zhao Chun, Cheng Yingying, Xu Linger, Fu Huihui, Yuan Yebo

引用次数: 0

A case of neonatal alloimmune neutropenia in premature infants with response to intravenous immunoglobulins 静脉注射免疫球蛋白有应答的早产儿新生儿同种免疫中性粒细胞减少1例

Pediatric dimensions Pub Date : 2019-01-01 DOI: 10.15761/pd.1000185

J. E., U. J

引用次数: 0