Pediatric dimensions最新文献

{"title":"Clinical application of ultrasound in paediatric diaphragmatic dysfunction","authors":"Xin Zhao, Zi-jian Tang, B. Xia","doi":"10.15761/pd.1000214","DOIUrl":"https://doi.org/10.15761/pd.1000214","url":null,"abstract":"","PeriodicalId":91786,"journal":{"name":"Pediatric dimensions","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67504038","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Racotumomab-alum vaccine as active immunotherapy for neuroectodermal pediatric tumors","authors":"M. Hernandez, Maria C. Gonzalez, Anaisa C. Amores, Juan C. Arranz, R. Gutiérrez, Lisania Reyes, Z. González, M. Labrada, C. Valenzuela, L. García, Adanay Calvo, Xiomara Reyes, Maria A. Miragaya, Pedro P. Guerra, O. Santos, T. Crombet","doi":"10.15761/pd.1000215","DOIUrl":"https://doi.org/10.15761/pd.1000215","url":null,"abstract":"","PeriodicalId":91786,"journal":{"name":"Pediatric dimensions","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67504131","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Review of a program for systematic intervention for children of preschool age with Autism Spectrum Disorder in Greece","authors":"S. Kotsopoulos","doi":"10.15761/pd.1000213","DOIUrl":"https://doi.org/10.15761/pd.1000213","url":null,"abstract":"","PeriodicalId":91786,"journal":{"name":"Pediatric dimensions","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67504473","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A study of MACI in patients aged 10 to 17 years with symptomatic chondral or osteochondral defects of the knee: Design and rationale","authors":"James L. Carey, Ann E Remmers, Theodore J Ganley","doi":"10.15761/pd.1000212","DOIUrl":"https://doi.org/10.15761/pd.1000212","url":null,"abstract":"","PeriodicalId":91786,"journal":{"name":"Pediatric dimensions","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67504460","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Thrombocytopenia related to multiple organ failure (TAMOF) related to extracorporeal circulation in cardiac surgery in paediatrics","authors":"Vera Ef, A. c, Lourdes M","doi":"10.15761/pd.1000200","DOIUrl":"https://doi.org/10.15761/pd.1000200","url":null,"abstract":"Aims and objectives: To determine the frequency of thrombocytopenia associated multi organ failure without infection criteria and its impact on the evolution and survival of patients undergoing cardiac surgery with extracorporeal circulation and prognosis. Methods : Longitudinal, prospective, observational study to determine the frequency in the presentation of thrombocytopenia associated with multiple organ failure in patients undergoing cardiac surgery under extracorporeal circulation without positive infection rates, admitted to the intensive care unit surgical (ICU). and its impact in the evolution of these patients in the Hospital Federico Gómez. Results: A total of 47 patients under extracorporeal circulation were analysed. Proportion for low cardiac output syndrome 23% (n = 11) being this complication most frequent presented by our patients, with a direct relationship to the appearance of TAMOF with a p <0.05, there is a direct relationship between the appearance of TAMOF in patients with> 140 minutes of extracorporeal circulation time, the presence of deep hypothermia, lactate more than 5 mmol / L on admission, a PSOFA score of more than 8 points, and a higher score on the RASCH risk scale with a p <0.05. There was a significant difference with a p <0.05 in the days of stay in therapy intensive, and mortality among patients who developed TAMOF and those who did not. Conclusions: The incidence of TAMOF associated with extracorporeal circulation during cardiac surgery in children and its role in impoverishment within the prognosis makes it important to identify this entity to establish action measures with appropriate therapies for these patients. It is it is necessary to normalize the ADAMTS 13 activity tests in children undergoing extracorporeal circulation.","PeriodicalId":91786,"journal":{"name":"Pediatric dimensions","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67503780","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prospective observational study of vital sign stability and safety of Osteopathic Manipulative Treatment (OMT) in neonates","authors":"A. Beinlich, Bryan Beck, K. Bendixen, Alexander B Craig","doi":"10.15761/PD.1000211","DOIUrl":"https://doi.org/10.15761/PD.1000211","url":null,"abstract":"Context: Despite various publications demonstrating efficacy of osteopathic manipulative therapy (OMT) in neonates, no studies have formally assessed the safety of OMT in this population. Objective: To determine the safety of OMT in term neonates (gestational age ≥ 37 weeks) and preterm neonates (gestational age ≤ 36 6/7 weeks). Safety was assessed using two mechanisms: 1) comparison of vital signs before and after OMT, and 2) monitoring for adverse events including emesis, cyanosis, apnea or decreased level of consciousness during OMT and for 30 minutes following OMT. Methods: A prospective observational design was used to analyze preand post-OMT measurements of temperature, heart rate, respiratory rate and oxygen saturation. Osteopathic physicians performed an osteopathic structural exam followed by OMT using techniques such as osteopathy in the cranial field, balanced ligamentous tension and myofascial release. Adverse events were documented by a research coordinator who observed the subject directly during OMT and for 30 minutes after OMT. Results: Thirty term and 13 preterm infants were recruited for this study. The mean gestational age at birth for the term infants was 37.8 weeks and 32.5 weeks for the preterm infants. The mean gestational age at the time of treatment was 40.0 weeks for the term population and 34.9 weeks for the preterm population. In both term and pre-term infants, the temperature decreased by a statistically significant 0.1°C following OMT. Heart rate decreased by 4 beats per minute (bpm) in term subjects and by 5 bpm in preterm subjects. Respiratory rate was unchanged in term infants and increased slightly in preterm infants. There was no change in oxygen saturations for either term or preterm infants. There were no adverse events in either group. Conclusion: The stability of vital signs preand post-OMT and absence of adverse events in this study suggest that OMT is a safe intervention to perform in healthy, term neonates. However, due to lower than anticipated recruitment of preterm neonates, safety cannot be formally declared for this population. *Correspondence to: Alexa Craig, Department of Pediatrics, Maine Medical Center, Portland, Maine, USA, E-mail: craiga@mmc.org Received: November 10, 2020; Accepted: December 15, 2020; Published: December 21, 2020 Introduction There is a small but growing body of evidence to support the efficacy of Osteopathic Manipulative Treatment (OMT) in preterm and term infants [1-6]. Osteopathic Medicine is a comprehensive system able to both diagnose and treat somatic dysfunctions through the refined skill of manual palpation [7]. Techniques commonly used in neonates include osteopathy in the cranial field (OCF), balanced ligamentous tension (BLT) and myofascial release (MFR) [7]. Through these techniques, OMT has been shown to improve efficiency of breast feeding [6], to reduce gastrointestinal symptoms [5], and to diminish infant colic [3]. Other studies have shown decreased length of ","PeriodicalId":91786,"journal":{"name":"Pediatric dimensions","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67504444","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Recent insights in Silver-Russell Syndrome","authors":"M. Raso, F. Chiarelli","doi":"10.15761/pd.1000205","DOIUrl":"https://doi.org/10.15761/pd.1000205","url":null,"abstract":"The aim of this review is to summarize the most recent information about Silver-Russell syndrome (SRS), a clinically and genetically heterogeneous imprinting disorder that causes prenatal and postnatal growth retardation. Particular attention was focused on several recommendations for clinical diagnosis and management of patients with SRS published by the Consensus Statement on SRS in 2017. Clinical aspects include intrauterine and postnatal growth retardation with relative macrocephaly, a typical triangular face, body asymmetry and other less specific features. Diagnosis is still challenging because of clinical diagnosis not often confirmed by molecular findings. Overlap exists between the care of children born small for gestational age and those with SRS. However, several recommendations are specific for SRS. Treatment goals can be achieved by a multidisciplinary team approach, but natural history of this disease should be studied by long-term follow up until adulthood.","PeriodicalId":91786,"journal":{"name":"Pediatric dimensions","volume":"69 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67503950","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"COVID 19: Physiotherapy performance in a pediatric intensive care unit","authors":"C. G. Ribas, V. Neves, E. F. D. Souza, A. Koliski, J. Carreiro","doi":"10.15761/PD.1000202","DOIUrl":"https://doi.org/10.15761/PD.1000202","url":null,"abstract":"The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a new coronavirus who emerged in 2019 and causes Coronavirus Disease 2019 (COVID-19) that is highly contagious and differs from other respiratory viroses. The transmition occurs by human-to-human approximately 2 to 10 days prior to the individual becoming symptomatic [1-4]. The COVID-19 in children is often less severe than in adults. It is children were usually well cared for at and might have relatively less opportunities to expose themselves to pathogens and/or sick patients. The angiotensin converting enzyme II (ACE2) is known as a SARS-CoV-2 /receptor and evidence has indicated that these receptors in children have less maturity and function than in adults. the or The higher younger children < 1 year of 3% In 13 critical cases, 7 younger than 1 year and only a 14 years old boy","PeriodicalId":91786,"journal":{"name":"Pediatric dimensions","volume":"129 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67503874","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Leech in the nasopharynx of an infant: A Case Report","authors":"S. Sadeghian, N. Sharafi, S. Sadeghian","doi":"10.15761/PD.1000207","DOIUrl":"https://doi.org/10.15761/PD.1000207","url":null,"abstract":"Introduction: Infestation with leeches can happen due to drinking from spring water or other unhealthy and non-hygienic sources of water or swimming in this infested water. Leech infestation can lead to serious problems in the aerodigestive tract. Case report: In this report, we described a 7-month-old infant presented to Abuzar Hospital of Ahvaz with hematemesis, epistaxis and bloody feces after drinking the Well water that led to leech entry into the nasopharynx. Removal was done, and the patient became symptom free. Conclusion: Infestation with a leech can lead to variable symptoms in the aerodigestive tract like bleeding from the mouth, nose and anus and irritation at the site of its attachment. So, sometimes it is important that keep leech infestation in our mind, especially, when patients live in rural or suburbs areas.","PeriodicalId":91786,"journal":{"name":"Pediatric dimensions","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67504263","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Efficacy and safety of azoximer bromide (Polyoxidonium) in children aged from 1 to 12 years with ARI: The results of a multicenter prospective, randomized, double-blind, placebo-controlled, parallel-group study","authors":"Garashchenko Ti, Karneeva Ov, Tarasova Gt, Kim Ia, Hanferian Ra","doi":"10.15761/pd.1000204","DOIUrl":"https://doi.org/10.15761/pd.1000204","url":null,"abstract":"Purpose: To confirm the superiority of the therapeutic effect of topical use of azoximer bromide (Polyoxidonium) in comparison with placebo in children from 1 to 12 years of age with ARVI. Patients and methods: The study included 155 children: the main group consisted of 76 children with azoximer bromide, the comparison group consisted of 79 children with placebo included in the complex treatment. The study evaluated the dynamics of intoxication symptoms, symptoms of inflammation of the nasal mucous membrane, the total sum of all symptoms in points to 3, 5 and 8 days of treatment, the duration of the fever period as criteria for evaluation the effectiveness of therapy. Results: According to the study results, the efficacy of azoximer bromide use in the complex therapy of children from 1 to 12 years with ARVI can be stated. Inclusion of azoximer bromide in the complex treatment of ARVI in children as compared to placebo allows to control better the symptoms of intoxication, to reduce the severity of symptoms of “nasal discharge” and “nasal congestion” by the 5th day of therapy, to increase twice the number of patients with no symptoms of “Nasal discharge” by the 3rd and 5th days of therapy, to reduce the severity of infectious and inflammatory process. The number of adverse events on the background of azoximer bromide use is not statically significantly different from the number of adverse events on the placebo use background, which indicates the safety of azoximer bromide. Conclusion: Topical use of azoximer bromide in complex treatment of ARVI in children from 1 to 12 years is clinically effective and safe. *Correspondence to: TTatyana Ilyinichna Garashchenko, Federal State Budgetary Institution, The National Medical Research Center for Otorhinolaryngology for the Federal Medico-Biological Agency of Russia, Russia, Tel: +79162360009, +79169040100; E-mail: 9040100@mail.ru Galina Dmitrievna Tarasova, Research Department of the Federal State Budgetary Institution, The National Medical Research Center for Otorhinolaryngology for the Federal Medico-Biological Agency of Russia, Russia, Tel: Phone +79166083431; E-mail: gtarasova@yandex.ru","PeriodicalId":91786,"journal":{"name":"Pediatric dimensions","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67503905","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}