{"title":"The study of using precise measurement to evaluate the outcomes after ear reconstruction","authors":"P. Zhu, Sui-jun Chen","doi":"10.15761/ohns.1000214","DOIUrl":"https://doi.org/10.15761/ohns.1000214","url":null,"abstract":"Objective: Microtia ear reconstruction is one of the most challenging operations in plastic surgery, the aim of the present study is to use a new method to evaluate the results after ear reconstruction. Study design: Observational study. Setting: University hospital from December 2016 to January 2018. Subjects and methods: In total, 40 children underwent autologous ear reconstruction with three-stage technique, 20 patients who had a 3D digital template made for clinical application, and the other 20 who had undergone ear reconstruction with a 2D template, all of the subjects had been on a more than 3-months postoperative follow-up. For the auricle’s 20 precise measurements which count, combined with satisfaction questionnaires, a complete review of anatomic features, surgical results were performed. Results: The measurement results of the 3D model group remanufactured ear profile were more correlated with the measurement results of the healthy side ear profile, while the patients in the 3D model group were more satisfied with the reconstructed ear profile, which was consistent with the clinical actual results, and objectively reflected the effect of the patient after the operation. Conclusion: The application of 3D model is helpful to improve the effect of surgery, and the precise measurement evaluation method combined with the satisfaction questionnaire can reflect the patient's postoperative effect in a realistic and objective way. *Correspondence to: Sui-jun Chen, Department of Otolaryngology, Sun Yatsen Memorial Hospital, Sun Yat-sen University, Guang Zhou, China, Tel: +86 20 8133 2199; E-mail: chensuij@mail.sysu.edu.cn","PeriodicalId":91783,"journal":{"name":"Otorhinolaryngology-head and neck surgery","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67501158","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M. Köping, R. Hagen, Schneider Michael, C. Beck, J. Grunz, A. Scherzad
{"title":"Well-differentiated liposarcoma of the hypopharynx: Two case reports and literature review","authors":"M. Köping, R. Hagen, Schneider Michael, C. Beck, J. Grunz, A. Scherzad","doi":"10.15761/ohns.1000208","DOIUrl":"https://doi.org/10.15761/ohns.1000208","url":null,"abstract":"","PeriodicalId":91783,"journal":{"name":"Otorhinolaryngology-head and neck surgery","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67500802","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
B. Sinjari, G. D’Addazio, F. Perfetti, S. Caputi, G. Murmura
{"title":"The usefulness of CBCT in early diagnosis of primary extra-nodal non-Hodgkin’s lymphoma in the mandible. A case report","authors":"B. Sinjari, G. D’Addazio, F. Perfetti, S. Caputi, G. Murmura","doi":"10.15761/OHNS.1000195","DOIUrl":"https://doi.org/10.15761/OHNS.1000195","url":null,"abstract":"Non-Hodgkin Lymphoma (NHL) is one of the rare malign diseases that can affect the oral cavity. In extranodal manifestations cranial bone could be affected by a massive destruction of bone tissue and invasion of the surrounding soft tissues. 3D radiology can help identifying suspicious lesions at an early stage and can support immunohistochemical examinations. Identifying clinically or radiologically these lesions and diagnosing them means saving patients’ lives. A clinical case of extranodal oral NHL manifestation, with remission at 5 years of follow-up, identified due to a Cone Beam Computed Tomography (CBCT) examination will be presented. *Correspondence to: Bruna Sinjari, Department of Medical Oral and Biotechnological Sciences, University G. d’Annunzio Chieti-Pescara, Via dei Vestini 31, 66100 Chieti (CH), Italy, Tel: +39 3927471479, Fax: +39 08713554070; E-mail: b.sinjari@unich.it","PeriodicalId":91783,"journal":{"name":"Otorhinolaryngology-head and neck surgery","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67500899","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Multiple paragangliomas involving carotid body and vagal region: A sporadic case","authors":"J. Bakshi, A. Goyal, D. Vir, Naresh K. Panda","doi":"10.15761/ohns.1000197","DOIUrl":"https://doi.org/10.15761/ohns.1000197","url":null,"abstract":"","PeriodicalId":91783,"journal":{"name":"Otorhinolaryngology-head and neck surgery","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67500986","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
P. Güneri, E. Maghami, H. Boyacıoğlu, A. Ho, J. Epstein
{"title":"Outcomes of surgical management of dysplastic oral mucosal lesions versus observation: A systematic analysis","authors":"P. Güneri, E. Maghami, H. Boyacıoğlu, A. Ho, J. Epstein","doi":"10.15761/OHNS.1000201","DOIUrl":"https://doi.org/10.15761/OHNS.1000201","url":null,"abstract":"Background: The aim was to investigate the outcomes of surgical management versus observation of dysplastic oral mucosal lesions. Method: Twenty-one papers met the a priori inclusion criteria, resulting in a total of 1943 lesions in 1599 patients. Epithelial dysplasia was grouped as “low-grade” and “high-grade”. Clinical outcome was established as the proportion of lesions with complete response, partial response, no response, malignant transformation, and recurrence/new lesions. Data on surgical intervention versus no treatment/observation was statistically analyzed. Results: Surgical management was provided in 80% of all lesions, versus observation in 20%. Following removal of lesions reported in studies without dysplasia, low grade dysplasia was reported in 59.9% of the oral potentially malignant disorders (OPMDs), and high-grade dysplasia in 40.1% of lesions. In the analysis, overall malignant outcome was 4.99%, and was similar in both the observation and surgical management groups (p = 0.554). The overall successful outcome (complete and partial responses) for all treatment was 45.31%, persistence or recurrences were observed in 27.99% of all OPMDs. In low grade lesions, there was no correlation between the complete or partial responses (p = 0.446), and the number of malignant transformation and recurrences/new lesions (p = 0.310). Similarly, in high grade lesions, no correlation was observed between the complete or partial responses (p = 0.140), and the number of malignant transformation and recurrences/new lesions (p = 0.673). Further analyses revealed no differences between the outcomes of surgical treatment and observation in low risk group (p = 0.358) and in high risk group (p = 0.258). Conclusion: This analysis shows that OPMDs treated by either surgical removal or observation alone have similar risks of malignant transformation irrespective of the degree of dysplasia, indicating the need for active surveillance of all dysplastic OPMDs. *Correspondence to: Pelin Güneri, Department of Oral and Maxillofacial Radiology, School of Dentistry, Ege University, Bornova, İzmir, Turkey, Tel: +902323881081; Fax: +902323880325; E-mail: peleen_2000@yahoo.com","PeriodicalId":91783,"journal":{"name":"Otorhinolaryngology-head and neck surgery","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67500621","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Bilateral chylothorax after neck dissection- A sporadic case with new treatment modality","authors":"Bakshi J, L. P, S. V","doi":"10.15761/ohns.1000196","DOIUrl":"https://doi.org/10.15761/ohns.1000196","url":null,"abstract":"","PeriodicalId":91783,"journal":{"name":"Otorhinolaryngology-head and neck surgery","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67500916","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
P. Clarós, A Karlikowska, A. Clarós-Pujol, Andrés Clarós, C. Pujol
{"title":"Dysphonia in opera singers due to psychogenic disorders","authors":"P. Clarós, A Karlikowska, A. Clarós-Pujol, Andrés Clarós, C. Pujol","doi":"10.15761/ohns.1000198","DOIUrl":"https://doi.org/10.15761/ohns.1000198","url":null,"abstract":"","PeriodicalId":91783,"journal":{"name":"Otorhinolaryngology-head and neck surgery","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67501019","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Foreign body in the airway of a premature infant: a fragment of suction catheter revisited","authors":"A. Yazici, B. Bilgin, S. Ünal","doi":"10.15761/OHNS.1000205","DOIUrl":"https://doi.org/10.15761/OHNS.1000205","url":null,"abstract":"Paediatric foreign body in the airway is usually seen in children aged 1-3 years and cause sudden respiratory distress. If the diagnosis is delayed or untreated, it may result in serious morbidity or even mortality. In new-borns, foreign body in the airways is rarely seen and it is usually formula or breast milk. We presented a premature hypotonic infant in need of mechanical ventilation transported to our unit on 49th day for tracheotomy. We identified left pulmonary atelectasis and a plastic tube fragment was removed from the left main bronchus by rigid bronchoscopy. *Correspondence to: Aybüke Yazici, Division of Neonatology, Health Science University, Ankara Children's Hematology and Oncology Research Hospital, Turkey, Tel: +90 312 5969730; Fax: +90 312 3472330; E-mail: dr.a.yazici@ hotmail.com","PeriodicalId":91783,"journal":{"name":"Otorhinolaryngology-head and neck surgery","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67500678","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
G. Zhu, D. Ma, Lusen Shi, Han Zhou, Jie Chen, Xia Gao
{"title":"A novel compound heterozygous mutation in the MYO15A gene in autosomal recessive hearing loss identified by targeted massively parallel sequencing","authors":"G. Zhu, D. Ma, Lusen Shi, Han Zhou, Jie Chen, Xia Gao","doi":"10.15761/OHNS.1000207","DOIUrl":"https://doi.org/10.15761/OHNS.1000207","url":null,"abstract":"Objectives: Inherited genetic defects are the most common causes of autosomal recessive nonsyndromic hearing loss (ARNSHL), affecting millions of people worldwide. Identification and specific molecular diagnosis of the pathogenic genes or loci would facilitate basic research of ARNSHL and its clinical prevention and treatment. Materials and methods: We identified the causal deafness gene of a Chinese family with ARNSHL using targeted massively parallel sequencing. We also used DNA from 51 Chinese familial patients with ARNSHL and 60 ethnicity-matched normal controls to perform extended variants analysis. Results: We detected a novel compound heterozygous mutation, c. 10419_10423delCAGCT and a previously reported mutation c. 6956+9C>G, in MYO15A gene in the proband. Both mutations co-segregated with hearing loss in the Chinese family in our study and were absent in the 51 index patients and 60 ethnicity-matched normal controls. Conclusion: We identified a novel c. 10419_10423delCAGCT frameshift mutation, which results in a truncated MYO15A protein that lacks part of the second FERM domain and PDZ-ligand at the C terminus. Our results demonstrate that the novel c. 10419_10423delCAGCT mutation, in compound heterozygosity with the previously reported c. 6956+9C>G splicing site mutation, is the underlying cause of ARNSHL in this Chinese family. Our study extends the mutation spectrum of the MYO15A gene for establishing a better understanding of DFNB3. *Correspondence to: Xia Gao, Department of Otorhinolaryngology-Head and Neck Surgery, Drum Tower Hospital affiliated with Nanjing University Medical School, Jiangsu Provincial Key Medical Discipline (Laboratory), No. 321 Zhongshan Road, Nanjing, 210008, China, Tel: (+86)-13951829819; E-mail: gaoxiadth@outlook.com","PeriodicalId":91783,"journal":{"name":"Otorhinolaryngology-head and neck surgery","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67500759","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Dangers of home do-it-yourself","authors":"Y. Lau, Yun Mei Lau, G. Wong","doi":"10.15761/ohns.1000213","DOIUrl":"https://doi.org/10.15761/ohns.1000213","url":null,"abstract":"","PeriodicalId":91783,"journal":{"name":"Otorhinolaryngology-head and neck surgery","volume":"10 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67501098","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}