Otorhinolaryngology-head and neck surgery最新文献_第2页

An unusual case of adenoid cystic carcinoma of nasal septum mimicking as chronic sinusitis 一例不寻常的鼻中隔腺样囊性癌假象为慢性鼻窦炎的病例

Otorhinolaryngology-head and neck surgery Pub Date : 2020-05-29 DOI: 10.15761/OHNS.1000233

Shama Shishodia, Udit Narayan, Srijan Sharma

引用次数: 2

Novel predictive factors of Bell’s Palsy: Neutrophil to lymphocyte ratio and platelet to lymphocyte ratio 贝尔氏麻痹的新预测因素:中性粒细胞与淋巴细胞比率和血小板与淋巴细胞比率

Otorhinolaryngology-head and neck surgery Pub Date : 2020-01-01 DOI: 10.15761/OHNS.1000242

A. Pokharel, Jaya Prakash Mayya

{"title":"Novel predictive factors of Bell’s Palsy: Neutrophil to lymphocyte ratio and platelet to lymphocyte ratio","authors":"A. Pokharel, Jaya Prakash Mayya","doi":"10.15761/OHNS.1000242","DOIUrl":"https://doi.org/10.15761/OHNS.1000242","url":null,"abstract":"Introduction: Inflammation plays an important role in the pathogenesis of Bell’s palsy. Neutrophil to lymphocyte ratio (NLR) and platelet to lymphocyte ratio (PLR) are indicators of inflammation. Objectives: The aim of this study was to find the prevalence of Bell's palsy and the mean of neutrophil to lymphocyte ratio and platelet to lymphocyte ratio among them. Methods: This descriptive cross-sectional study was conducted from 1st March 2018 to 1st March 2020 after receiving ethical approval from Institutional Review Committee (Ref. No: 2020-046). Convenience sampling method was used for case selection. Data entry and analysis were done in Statistical Package for the Social Sciences Version 20. Point estimate at 95% confidence interval was calculated along with frequency and proportion for binary data. Result: Out of all patients who visited ENT outpatient department during the study period, the overall prevalence of Bell’s palsy was 0.6% (117) at a 95% confidence interval (0.5-0.72%). Among them, the mean neutrophil to lymphocyte ratio was 5.014 ± 1.63, and the mean platelet to lymphocyte ratio was 207.38 ± 54.59. Conclusion: NLR and PLR can be used as auxiliary param eters in the management of Bell’s palsy. *Correspondence to: Apar Pokharel, College of Medical Sciences, Chitwan, Nepal, Tel: +977-9855058234; E-mail: apar.pokharel@gmail.com","PeriodicalId":91783,"journal":{"name":"Otorhinolaryngology-head and neck surgery","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67501289","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Bleeding after tonsillectomy was associated to hypertension and dissection with diathermy, but not surgical experience 扁桃体切除术后出血与高血压和热疗夹层有关，但与手术经验无关

Otorhinolaryngology-head and neck surgery Pub Date : 2020-01-01 DOI: 10.15761/OHNS.1000239

Karl Knoph, M. Eriksson, L. Farnebo

{"title":"Bleeding after tonsillectomy was associated to hypertension and dissection with diathermy, but not surgical experience","authors":"Karl Knoph, M. Eriksson, L. Farnebo","doi":"10.15761/OHNS.1000239","DOIUrl":"https://doi.org/10.15761/OHNS.1000239","url":null,"abstract":"Objective: To analyze risk factors for postoperative bleeding after tonsillectomy (TE), and differences in bleeding frequency between 2017 and 2018. Study design: This is a retrospective cohort study. Setting: The Department of Otorhinolaryngology – Head and Neck Surgery, region of Östergötland, Sweden. Methods: This retrospective cohort study included all 402 consecutive cases of TE in the region of Östergötland, Sweden 2017-2018. Patients were followed for at least 30 days after surgery. Demographics, comorbidity, surgical experience, potential risk factors and postoperative complications were registered. The primary endpoint was postoperative bleeding. Results: Twenty-four of 402 (6%) patients had a postoperative bleeding after tonsillectomy. Hypertension and dissection with bipolar diathermy respectively were identified as independent, statistically significant risk factors for bleeding, in both uniand multivariate analysis. Surgical experience was not significantly associated to bleedings after TE. Conclusion: Hypertension and dissection with bipolar diathermy are individual risk factors for postoperative bleeding following tonsillectomy, but not surgical experience. *Correspondence to: Lovisa Farnebo, Department of OtorhinolaryngologyHead and Neck Surgery, Linköping University Hospital, 58185 Linköping, Sweden, Tel: +46702640330; E-mail: lovisa.farnebo@regionostergotland.se","PeriodicalId":91783,"journal":{"name":"Otorhinolaryngology-head and neck surgery","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67501233","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Salient factors identification in head and neck cancer survival 头颈癌生存的重要因素鉴定

Otorhinolaryngology-head and neck surgery Pub Date : 2020-01-01 DOI: 10.15761/OHNS.1000231

D. Liberati

{"title":"Salient factors identification in head and neck cancer survival","authors":"D. Liberati","doi":"10.15761/OHNS.1000231","DOIUrl":"https://doi.org/10.15761/OHNS.1000231","url":null,"abstract":"Volume 5: 1-1 Some 20 years ago head and neck cancer were still considered as a rare tumour: nowadays Lisa, our bright physician co-author in an article [1], is director of a deputy structure at National Cancer Institute in Milano. In Drago GP et al.’s [1] article we were trying to asses radiochemistry as yet not consolidated protocol. To do that, as a by-product we were able to prune the whole set of the traditionally measured data in every subject, showing that the 11 factors reported in figure 1 (taken from [1]) were sufficient not only to discriminate output but also to improve signal to noise ratio with respect to the use of all the data set: being world not linear, it was and it is not in generally true that more are the data, more is the info: often too not specific data hidden the very core of the underlying process. Not surprising, the most salient factor is the easiest one to measure without instruments, felt by good physicians on the basis of the general dynamical aspect of the patient: in fact, a popular say says that the main prognostic factor is the physician caring for you, embedding in almost a joke both the notion of competence and empathy. A not so different joke, dear to a former scientific director of Italian Cancer Institute in Milano, is that if you get in, even with just a cold (phopehtic, seen from nowadays :) you could get only get out horizontal! Other factors are pretty obvious, we will not discuss them here. Radio chemio is nowadays standard: better than just chemio after the most possibly radical surgery.","PeriodicalId":91783,"journal":{"name":"Otorhinolaryngology-head and neck surgery","volume":"24 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67501083","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Association analysis of LDLR gene polymorphisms with susceptibility to sudden deafness LDLR基因多态性与突发性耳聋易感性的相关性分析

Otorhinolaryngology-head and neck surgery Pub Date : 2020-01-01 DOI: 10.15761/OHNS.1000237

Long Cui, W. Xin, Jiawen Chen, Weijun Ma, Panhong Dang, M. Duan, Xiao-tong Zhang

{"title":"Association analysis of LDLR gene polymorphisms with susceptibility to sudden deafness","authors":"Long Cui, W. Xin, Jiawen Chen, Weijun Ma, Panhong Dang, M. Duan, Xiao-tong Zhang","doi":"10.15761/OHNS.1000237","DOIUrl":"https://doi.org/10.15761/OHNS.1000237","url":null,"abstract":"In order to explore the association of 3 SNPs of LDLR gene with susceptibility to sudden deafness (SD), serum lipid parameters were compared in 139 SD patients and 139 healthy individuals. Genotyping of the 3 SNPs, allele and genotype frequencies were performed and compared. The association between allele frequency of 3 SNPs and susceptibility to SD in different models were analysed. Serum lipid parameters were compared in patients with different genotypes. The comparison of serum lipid levels showed higher triglycerides, total cholesterol, and low-density lipoprotein cholesterol levels in patients compared to the controls. The frequencies of rs5929 T allele, rs2738464 G allele and rs1433099 T allele in SD group were higher than control group. We observed a statistically significant association of LDLR gene rs5929 T allele under dominant genetic model, rs2738464 G allele under additive and dominant genetic models, rs1433099 T allele under dominant genetic model with susceptibility to SD. There was no statistical difference in serum lipid levels of SD patients with different genotypes. Total cholesterol, triglycerides, and low-density lipoprotein cholesterol may be risk factors in the pathogenesis of SD. rs5929 T allele, rs2738464 G allele and rs1433099 T allele may be risk factors for SD. *Correspondence to: Xiaotong Zhang, Department of OtorhinolaryngologyHead and Neck Surgery, The Second Affiliated Hospital of Xi’an Jiaotong University, No. 157. West 5th Road, Xi'an City, Shaanxi Province, China, Tel: 86 29 8266 8888; E-mail: tracylizhang@189.cn","PeriodicalId":91783,"journal":{"name":"Otorhinolaryngology-head and neck surgery","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67501176","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Iatrogenic esophageal rupture due to anterior cervical spine surgery 颈椎前路手术致医源性食管破裂

Otorhinolaryngology-head and neck surgery Pub Date : 2020-01-01 DOI: 10.15761/OHNS.1000252

K. Athanassiadi, M. Fratzoglou, D. Xenis, S. Pispirigkou, E. Papadopoulos, A. Rogdakis

{"title":"Iatrogenic esophageal rupture due to anterior cervical spine surgery","authors":"K. Athanassiadi, M. Fratzoglou, D. Xenis, S. Pispirigkou, E. Papadopoulos, A. Rogdakis","doi":"10.15761/OHNS.1000252","DOIUrl":"https://doi.org/10.15761/OHNS.1000252","url":null,"abstract":"Anterior cervical corpectomy from C2–T1 is being used to decompress and reconstruct the cervical spine for a wide variety of degenerative disorders, trauma, neoplasms, and infectious disorders or as a salvage surgery for correcting kyphotic deformities and vertebral collapse. The technique minimally disrupts normal cervical muscles and is associated with a low risk of injuring surrounding structures such as esophagus. A case of an iatrogenic esophageal wall perforation subsequent to cervical corpectomy through an anterior approach along with a review of the literature and an algorithm of treatment are presented. A 52-year-old, emphysematous man underwent anterior cervical stabilization using plate and screw for vertebral collapse of the C5 vertebra followed by a huge cervicofacial subcutaneous emphysema on the 1 st postoperative day. A cervical and chest CT was performed and revealed a rupture of esophagus at the site of the plate. The rupture was also confirmed by an esophagogram. The patient was led directly to surgery. During the procedure, the implant was in place, but a large defect was found along the posterior wall of the cervical part of the esophagus. The patient underwent wide drainage of the prevertebral space, direct repair of the defect of the esophagus with separate sutures and formation of a pedicle flap with sternocleidomastoideus and infrahyoid muscles leaving the osteosynthetic plate in place. Postoperatively he developed respiratory insufficiency and stayed intubated for 10 days in the ICU under antibiotic treatment. After a hospitalization of 24 days he was discharged and in a follow up of 6 months there was no recurrence. In during can be potentially life threatening. Early of the injury followed by case morbidity and mortality.","PeriodicalId":91783,"journal":{"name":"Otorhinolaryngology-head and neck surgery","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67501349","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A peculiar case of hearing loss followed years later by tinnitus and vertigo 一例特殊的听力损失，多年后伴有耳鸣和眩晕

Otorhinolaryngology-head and neck surgery Pub Date : 2019-12-06 DOI: 10.15761/OHNS.1000219

V. Marcelli, M. Cavaliere, M. Mesolella, E. Cantone, A. M. D. Lullo, Carla Laria, P. Apisa, Rita Malesci, E. Bernardo, F. Ricciardiello, Elisabetta Cristiano, Salvatore Mazzone, C. Tripodi, A. Marzetti, G. Auletta, G. Tortoriello

引用次数: 0

A case report of giant rhinophyma 巨大鼻肿1例

Otorhinolaryngology-head and neck surgery Pub Date : 2019-01-01 DOI: 10.15761/OHNS.1000194

G. Cabrini, Pasquina La Torre, Antonio Buonamico, G. Quaternato, L. Neri, G. Neri

{"title":"A case report of giant rhinophyma","authors":"G. Cabrini, Pasquina La Torre, Antonio Buonamico, G. Quaternato, L. Neri, G. Neri","doi":"10.15761/OHNS.1000194","DOIUrl":"https://doi.org/10.15761/OHNS.1000194","url":null,"abstract":"Introduction: We present the case of a man with a giant rhinophyma, a very rare nasal disorder. Case presentation: A 89 years old man had been observing a rapid increase in the size of the nose in the last eight years. He had been reporting difficulty in breathing through the nose and mouth and intaking food for months. The aesthetic aspect, severely compromised, had determined the isolation of the subject even from family members. We decided to operate the rhinophyma completely by using sharp scalpel incision and electrosurgical knife assisted dissection. Histological examination of the biopsy specimens revealed a hyperkeratosis of the epidermis and cystic expansion of ducts in dermis. After excision, the recovery of normal physiognomy has led to the recovery of social and family relationships. Conclusion: In our experience it affords the surgeon the ability to rapidly and accurately sculpt the nose to an excellent aesthetic result. In advanced forms of rhinophyma, when the tumor is giant, the main method of treatment is surgery. *Correspondence to: Giorgio Cabrini, Department of Neuroscience, Imaging and clinical Sciences, University “G. D’Annunzio” of Chieti-Pescara, Hospital “S.S. Annunziata”, Via dei Vestini, 66100 Chieti, Italy, Tel: +39-087-135-71; E-mail: giorgio2090@gmail.com","PeriodicalId":91783,"journal":{"name":"Otorhinolaryngology-head and neck surgery","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67500889","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Neuroendocrine carcinoma of the oropharynx: A report of two cases and literature review 口咽部神经内分泌癌2例报告并文献复习

Otorhinolaryngology-head and neck surgery Pub Date : 2019-01-01 DOI: 10.15761/ohns.1000210

E. Omakobia, S. Sood, D. Gouldesbrough, K. Cardale, K. Dyker, D. Sutton, R. Glore

{"title":"Neuroendocrine carcinoma of the oropharynx: A report of two cases and literature review","authors":"E. Omakobia, S. Sood, D. Gouldesbrough, K. Cardale, K. Dyker, D. Sutton, R. Glore","doi":"10.15761/ohns.1000210","DOIUrl":"https://doi.org/10.15761/ohns.1000210","url":null,"abstract":"Background: Neuroendocrine carcinoma (NEC) of the oropharynx is extremely rare, with only 42 cases reported since first identified in 1972. There is no consensus on optimal management. Methods: Two cases of oropharyngeal NEC were identified at our institution. We reviewed the presenting features, radiological findings, histopathology and management, before conducting a literature review to evaluate treatment and survival for such patients. Results: Final diagnoses were confirmed to be T2 N1 M0 poorly differentiated NEC of the left palatine tonsil and T2 N2c M0 large cell NEC of the left soft palate. Following discussion in our multidisciplinary meeting, chemotherapy combined with radiotherapy was deemed the most appropriate treatment. Conclusions: NEC of the oropharynx is a rare and aggressive condition with a poor prognosis. Standardised treatment guidelines have not yet been established but the overriding opinion favours chemotherapy combined with radiotherapy. For locally advanced disease, surgery appears to have little impact on overall survival. HPV status should be checked in confirmed cases to help better understand the association between HPV and oropharyngeal NEC with regard to prognosis. *Correspondence to: Eugene G Omakobia, Department of ENT and Head and Neck Surgery, Bradford Teaching Hospitals, NHS Trust, Bradford, UK, Tel: 07460 319 256; E-mail: eugeneomakobia@doctors.org.uk","PeriodicalId":91783,"journal":{"name":"Otorhinolaryngology-head and neck surgery","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67500940","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Possible clinical implication of eosinophil extracellular traps in eosinophilic otitis media 嗜酸性中耳炎嗜酸性粒细胞胞外陷阱可能的临床意义

Otorhinolaryngology-head and neck surgery Pub Date : 2019-01-01 DOI: 10.15761/ohns.1000212

N. Ohta, S. Ueki, M. Hirokawa, Sachiko Tomioka-Matsutani, T. Kawano, T. Miyasaka, Tomoko Takahashi, Yutaka Nakamura, I. Ohno, S. Fujieda

引用次数: 1