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Journal of pigmentary disorders最新文献

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Phototherapy versus Adapalene 0.1% Gel in Treatment of Acne Vulgaris 光疗与0.1%阿达帕林凝胶治疗寻常性痤疮的比较
Journal of pigmentary disorders Pub Date : 2017-11-03 DOI: 10.4172/2376-0427.1000259
A. Bani, Mevlud Hoxha, Anisa Kondakciu
{"title":"Phototherapy versus Adapalene 0.1% Gel in Treatment of Acne Vulgaris","authors":"A. Bani, Mevlud Hoxha, Anisa Kondakciu","doi":"10.4172/2376-0427.1000259","DOIUrl":"https://doi.org/10.4172/2376-0427.1000259","url":null,"abstract":"Background: Phototherapy has been increasingly used for treatment of acne vulgaris. The targets of the action mechanism of each light treatment are generally thought to be P. acnes. Visible light has been proposed to work by decreasing P. acnes bacterial counts by activating endogenous porphyrins. Objective: To evaluate the effectiveness of phototherapy with Pulsed Light and Heat Energy (LHE) versus topical Adapalene 0.1% in the treatment of mild forms of acne. Method: During the period of 2 years were treated 99 patients with Acne vulgaris, 51 with mild form of Acne vulgaris were treated with Phototherapy and 48 patients with mild form were treated with topical Adapalene 0.1%.The effectiveness was based on the number of inflammatory and non-inflammatory elements in the beginning moment of therapy and in the intervals after two sessions, 4 sessions, 6 sessions, 8 sessions, one month after treatment with Phototherapy and after 2, 4, 6, 8, 10, 12 weeks treatment with Adapalene 0.1% Gel. Results: One month after the treatment with Phototherapy, the inflammatory and non-inflammatory elements cleaning reached 67.9 ± 6.2% in mild form and 68.4 ± 6.5% in moderate form of Acne vulgaris. Three months after the treatment with local treatment, the inflammatory and non-inflammatory elements cleaning reached 59.4 ± 5.8 in mild form and 71.4 ± 7.2 after treatment with local plus systemic in moderate form of Acne vulgaris. Conclusion: The treatment of Acne vulgaris with phototherapy LHE as mono-therapy is a medical alternative which gives good clinical results in a relatively short period of time (one month) and with minimal side effects.","PeriodicalId":91761,"journal":{"name":"Journal of pigmentary disorders","volume":"4 1","pages":"1-6"},"PeriodicalIF":0.0,"publicationDate":"2017-11-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46988725","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Premature Greying of Hair (Premature Canities): A Concern for Parent and Child 毛发过早变灰（早产犬）：父母和孩子的担忧
Journal of pigmentary disorders Pub Date : 2017-11-03 DOI: 10.4172/2376-0427.1000260
P. Nigam, P. Nigam
{"title":"Premature Greying of Hair (Premature Canities): A Concern for Parent and Child","authors":"P. Nigam, P. Nigam","doi":"10.4172/2376-0427.1000260","DOIUrl":"https://doi.org/10.4172/2376-0427.1000260","url":null,"abstract":"Hair goes grey with chronological aging. Premature hair greying may have significant adverse effects on the appearance, self-esteem, and socio-cultural acceptance of the affected individual. The exact aetiopathogenetic mechanism causing premature greying is still not clear and much speculative. Premature canities may appear alone as an autosomal dominant trait or it may occur in association with certain other disorders. The genes Pax3 and MITE play an important role in melanocyte stem cell maintenance and differentiation. Defective melanosomal transfer to the cortical keratinocytes or melanin incontinence due to melanocyte degeneration is also believed to contribute to greying. Despite the extensive molecular research being carried out to understand the pathogenesis of canities, treatment options still remain far from satisfactory and no effective therapy is available. Premature greying is a feature in a number of well recognised syndromes. A number of other conditions have also been observed to be associated with premature greying of hair.","PeriodicalId":91761,"journal":{"name":"Journal of pigmentary disorders","volume":" ","pages":"1-6"},"PeriodicalIF":0.0,"publicationDate":"2017-11-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.4172/2376-0427.1000260","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48224570","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 9
Erythema Dyschromicum Perstans: A Case Report 持久性变色红斑1例报告
Journal of pigmentary disorders Pub Date : 2017-09-20 DOI: 10.4172/2376-0427.1000266
K. Durmaz, İlkay Özer, S. Fındık, Pembe Oltulu, A. Ataseven
{"title":"Erythema Dyschromicum Perstans: A Case Report","authors":"K. Durmaz, İlkay Özer, S. Fındık, Pembe Oltulu, A. Ataseven","doi":"10.4172/2376-0427.1000266","DOIUrl":"https://doi.org/10.4172/2376-0427.1000266","url":null,"abstract":"Erythema dyscromicum perstans (EDP) or Ashy dermatosis is an uncommon pigmentary disorders which characterized with asymptomatic gray symmetric confluent macules over the body. It usually starts between first to three decades of the life and has a slow onset. This ailment can affect the palms, soles, scalp, nails and mucous membranes. Despite the definition of some etiological factors, the exact etiology of EDP is not clear. In this paper, we present a 24 years old patient with EDP.","PeriodicalId":91761,"journal":{"name":"Journal of pigmentary disorders","volume":"2017 1","pages":"1-2"},"PeriodicalIF":0.0,"publicationDate":"2017-09-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49167750","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Verapamil as Alternative Treatment in Hypertrophic and Keloid Scars 维拉帕米作为肥厚性瘢痕和瘢痕疙瘩的替代治疗
Journal of pigmentary disorders Pub Date : 2017-09-13 DOI: 10.4172/2376-0427.1000265
Guillermo Ramos-Gallardo, Diego Ricardo Delgado-Hernández, José Alberto Cervantes-López, Alexis Ivan García-Minjarez, Damaris Leticia Núñez-González, Sandra Figueroa-Jiménez, Leonel García-Benavides
{"title":"Verapamil as Alternative Treatment in Hypertrophic and Keloid Scars","authors":"Guillermo Ramos-Gallardo, Diego Ricardo Delgado-Hernández, José Alberto Cervantes-López, Alexis Ivan García-Minjarez, Damaris Leticia Núñez-González, Sandra Figueroa-Jiménez, Leonel García-Benavides","doi":"10.4172/2376-0427.1000265","DOIUrl":"https://doi.org/10.4172/2376-0427.1000265","url":null,"abstract":"Hypertrophic and keloid scars represent one of the main aesthetic and functional defects in patients after trauma, surgery, or burn. There are different therapeutic approaches used for these conditions, each showing varied results. Verapamil is a selective L-type calcium channel antagonist, which is currently considered as an alternative treatment in hypertrophic and keloid scars. Verapamil reduces the production of extracellular matrix, enhances collagenase secretion, and inhibits Interleukin 6 (IL-6), vascular endothelial growth factor (VEGF) and fibroblast cell proliferation. It also reduces the expression of transforming growth factor beta 1 (TGF-β1), subsequently inducing apoptosis. Verapamil is hereby proposed as an alternative and effective therapy for hypertrophic and keloid scars.","PeriodicalId":91761,"journal":{"name":"Journal of pigmentary disorders","volume":"2017 1","pages":"1-3"},"PeriodicalIF":0.0,"publicationDate":"2017-09-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.4172/2376-0427.1000265","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70307000","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Congenital Primary Milium on Nipple in a 3 Month Old Female Infant 3个月大女婴乳头先天性乳糜泻1例
Journal of pigmentary disorders Pub Date : 2017-08-05 DOI: 10.4172/2376-0427.1000E110
A. Tiwary
{"title":"Congenital Primary Milium on Nipple in a 3 Month Old Female Infant","authors":"A. Tiwary","doi":"10.4172/2376-0427.1000E110","DOIUrl":"https://doi.org/10.4172/2376-0427.1000E110","url":null,"abstract":"Milia are quite common benign keratin cysts. Its distribution and course depends upon whether it is primary or secondary in origin. The characteristic clinical presentation usually makes the diagnosis but on rare instances, histopathologic confirmation is warranted if primary milium is located on atypical sites. Here we report a case of congenital primary milium of nipple in a 3 month old female infant.","PeriodicalId":91761,"journal":{"name":"Journal of pigmentary disorders","volume":" ","pages":"1-1"},"PeriodicalIF":0.0,"publicationDate":"2017-08-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46552008","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Symmetric Plantar Melanocytic Nevi - Site-Specific Phenomenon or Pure Chance 对称性足底黑色素细胞痣-位点特异性现象或纯粹偶然性
Journal of pigmentary disorders Pub Date : 2017-06-30 DOI: 10.4172/2376-0427.1000264
S. Krengel, O. Haase
{"title":"Symmetric Plantar Melanocytic Nevi - Site-Specific Phenomenon or Pure Chance","authors":"S. Krengel, O. Haase","doi":"10.4172/2376-0427.1000264","DOIUrl":"https://doi.org/10.4172/2376-0427.1000264","url":null,"abstract":"Background: Predilection sites of melanocytic nevi are highly variable; however, individual patterns (e.g. preponderant involvement of extremities, trunk, etc.) are often noticed. A symmetric appearance of nevi on both sides of the body has not been reported. Objective: Guided by an initial, incidental observation of symmetrically arranged plantar nevi, a prospective survey of palmoplantar nevi was carried out. Methods: Between January 2016, and January 2017, 886 patients underwent a full-body examination for skin cancer screening. Special attention was paid to the pigmentary characteristics of the palms and soles. Results: 12/886 patients exhibited symmetrically or nearly symmetrically distributed plantar nevi (1.35%; mean age 45 years; male-female ratio 1:1). The nevi were mostly situated on the medial part of the plantar arch (9/12 cases; 75%). Remarkably, not a single case of symmetric nevi was identified on the palms. Conclusion: Arguments in favour of the specifity of the finding are: 1) the lack of comparable findings in palmar skin, i.e., in a similar histological compartment and 2) the predominant localization in the foot arch. Symmetric plantar nevi appear to be a rare, but not a random event. Possible underlying causes of this phenomenon are discussed.","PeriodicalId":91761,"journal":{"name":"Journal of pigmentary disorders","volume":"2017 1","pages":"1-3"},"PeriodicalIF":0.0,"publicationDate":"2017-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42921157","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Visualization of Different Morphological Structures within Pigmented Melanocytic Skin Lesion Melanoma: Case Studies 黑色素细胞皮肤病变黑色素瘤内不同形态结构的可视化:案例研究
Journal of pigmentary disorders Pub Date : 2017-04-24 DOI: 10.4172/2376-0427.1000262
I. Drljević, K. Drljević
{"title":"Visualization of Different Morphological Structures within Pigmented Melanocytic Skin Lesion Melanoma: Case Studies","authors":"I. Drljević, K. Drljević","doi":"10.4172/2376-0427.1000262","DOIUrl":"https://doi.org/10.4172/2376-0427.1000262","url":null,"abstract":"Dermoscopy is valid, non-invasive technique for the visualization of different morphological structures within pigmented melanocytic skin lesion. In clinical practice, positive personal history is considered to be as an indication of increased melanoma risk. The thickness of melanoma (Breslow Index) is the most important independent predicting factor of survival for stage I patients. We aimed to present two cases of head-melanoma and discuss prominent clinical and dermoscopic features across the spectrum of “hidden-melanoma” and differential diagnosis.","PeriodicalId":91761,"journal":{"name":"Journal of pigmentary disorders","volume":" ","pages":"1-3"},"PeriodicalIF":0.0,"publicationDate":"2017-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45845745","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Trichosporon asahii Causing Skin Lesions upon Ileostomy and Ureterostomies in an Immunodeficient Patient: A Case Report and a Mini Review of the Literature 阿萨伊毛孢子菌致免疫缺陷患者回肠切开术和输尿管切开术后皮肤损伤一例报告及文献复习
Journal of pigmentary disorders Pub Date : 2017-04-19 DOI: 10.4172/2376-0427.1000263
S. Karapsias
{"title":"Trichosporon asahii Causing Skin Lesions upon Ileostomy and Ureterostomies in an Immunodeficient Patient: A Case Report and a Mini Review of the Literature","authors":"S. Karapsias","doi":"10.4172/2376-0427.1000263","DOIUrl":"https://doi.org/10.4172/2376-0427.1000263","url":null,"abstract":"A case of superficial skin lesions due to T. asahii is reported, concerning an immune-deficient patient while receiving micafungin. Yet, T. asahii is assumed as intrinsically resistant to echinocandines. Thus, compared to echinocandines, azoles should be preferred in antifungal prophylaxis of immunosuppressed patients because they treat a wider variety of opportunistic fungi, including T. asahii. Additionally, T. asahii should be regarded as a potential pathogen causing skin lesions in immune-depressed or surgical patients.","PeriodicalId":91761,"journal":{"name":"Journal of pigmentary disorders","volume":"4 1","pages":"1-2"},"PeriodicalIF":0.0,"publicationDate":"2017-04-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44461360","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Pigmentary Disorders: The Bizarre Truth of Pigmentary Disorders 色素性疾病：色素性疾病的离奇真相
Journal of pigmentary disorders Pub Date : 2017-04-17 DOI: 10.4172/2376-0427.1000E109
H. Chen
{"title":"Pigmentary Disorders: The Bizarre Truth of Pigmentary Disorders","authors":"H. Chen","doi":"10.4172/2376-0427.1000E109","DOIUrl":"https://doi.org/10.4172/2376-0427.1000E109","url":null,"abstract":"Firstly, the spectrum of vitiligo is reviewed. The treatment of vitiligo with co-culture of melanocytes derived from hair follicle with adiposederived stem cells was also studied. In this study, stem cell concentration appeared to be one of the major factors affecting the degree of repigmentation. The use of NB-UVB after intraepidermal injection of melanocyte also showed highly statistically significance in repigmentation [1-5].","PeriodicalId":91761,"journal":{"name":"Journal of pigmentary disorders","volume":"4 1","pages":"1-1"},"PeriodicalIF":0.0,"publicationDate":"2017-04-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44978951","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Demodex Outbreak Causing Palpebra Skin Lesions Demodex爆发导致Palpebra皮肤损伤
Journal of pigmentary disorders Pub Date : 2017-03-14 DOI: 10.4172/2376-0427.1000261
Karapsias Stergios, A. Patelis, A. Sgourou
{"title":"Demodex Outbreak Causing Palpebra Skin Lesions","authors":"Karapsias Stergios, A. Patelis, A. Sgourou","doi":"10.4172/2376-0427.1000261","DOIUrl":"https://doi.org/10.4172/2376-0427.1000261","url":null,"abstract":"Demodex spp may cause blepharitis and palpebra skin lesions. Since eyelash demodicosis seems to be quite spreadable in the community, every patient with chronic non-diagnosed blepharitis should be examined for Demodex spp. Tea tree oil treatment may be an efficient and safe therapeutical choice against ocular demodicosis.","PeriodicalId":91761,"journal":{"name":"Journal of pigmentary disorders","volume":" ","pages":"1-2"},"PeriodicalIF":0.0,"publicationDate":"2017-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47714014","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
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