Journal of arthritis最新文献_第7页

Can Vitamin D Slow Progression of Osteoarthritis 维生素D能减缓骨关节炎的进展吗

Journal of arthritis Pub Date : 2017-02-06 DOI: 10.4172/2167-7921.1000232

V. Ch, J. Prakash, Md. Tashfeen Ashraf, Varsha Gupta

{"title":"Can Vitamin D Slow Progression of Osteoarthritis","authors":"V. Ch, J. Prakash, Md. Tashfeen Ashraf, Varsha Gupta","doi":"10.4172/2167-7921.1000232","DOIUrl":"https://doi.org/10.4172/2167-7921.1000232","url":null,"abstract":"Osteoarthritis (OA) is a chronic and prevalent joint disease resulting in degenerative changes in the cartilage. Now-a-days vitamin-D is emerging as an important component which has a wide biological effects. The studies are evaluating the beneficial effects of vitamin-D in osteoarthritis therefore the present investigation was planned to analyze i) levels of vitamin-D in selected controls and OA patients, ii) monitor gene expression changes in CYP2R1, CYP3A4, CYP27B1, CYP24A1 and CYP27A1, whose products are involved in vitamin D metabolism. Our result shows that there was no significant difference in the vitamin-D levels in OA versus controls. The mean vitamin D levels in controls was 35.9 ng/ml (3 had ViD<20g/ml) and in OA patients was 35.66 ng/ml (3 had Vit D<20ng/ml). However gene expression of CYP2R1, CYP3A4 was reduced CYP24A1, CYP27B1 showed no variation in expression and CYP27A1 was upregulated in OA patients as compared to control. We could not observe significant difference in the levels of vitamin D in control and patient showing that onset of primary OA may not be because of vitamin D deficiency or vitamin D may not be responsible for symptoms of OA. However its supplementation may have therapeutic benefits to all including control and patients as vitamin D levels are not optimum in both. Lower gene expression of cytochrome p 450 genes suggest some effects on OA patients but these are related to age or post-menopausal stage or OA is not clear as in our study we were unable to obtain primary OA patients without any comorbidity with <55 years of age. OA in less than 55 years are mostly associated with comorbid conditions as diabetes, hypertention, thyroid, obesity, chronic gastrointestinal disturbance, kidney or liver disease, with trauma etc.","PeriodicalId":91304,"journal":{"name":"Journal of arthritis","volume":" ","pages":"1-5"},"PeriodicalIF":0.0,"publicationDate":"2017-02-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48736805","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Scintimetric Evaluation of the Rheumatoid Arthritis Involvement by Dr. V. Siva’s Retention Ratio-(Preliminary Report) V.Siva博士保留率对类风湿性关节炎影响的闪烁评估（初步报告）

Journal of arthritis Pub Date : 2017-01-20 DOI: 10.4172/2167-7921.1000231

Sivasubramaniyan, K. Venkataramaniah

{"title":"Scintimetric Evaluation of the Rheumatoid Arthritis Involvement by Dr. V. Siva’s Retention Ratio-(Preliminary Report)","authors":"Sivasubramaniyan, K. Venkataramaniah","doi":"10.4172/2167-7921.1000231","DOIUrl":"https://doi.org/10.4172/2167-7921.1000231","url":null,"abstract":"Aim: This study aims to propose the utility of Scintimetric Characterization of the tracer activity uptake in the joints afflicted by Rheumatoid arthritis in the bone scans. Materials and method: Three out of five patients of confirmed Rheumatoid arthritis who had bone scans for Bone and joint pains showed presence of skeletal hot spots in various joints. They were subjected to the scintimetric evaluation of the skeletal hot spots by Dr. V. Siva’s retention ratio by repeating the 24 hr delayed bone scans. The 58 skeletal hotspots seen in various joint spaces were subjected to the calculation of maximum counts in 3 hr and 24 hr bone scans. They were tabulated and 3/24 hr Dr. V. Siva’s Retention Ratio was calculated and analysed. Results: They showed a mean of 5.91 ± 0.35 and standard error of means as 0.3496. The estimated variance was 8.8408 and the estimated standard deviation was 2.9734. For this sample size the estimated variance was 6.6306 and estimated standard deviation was 2.575 by HOJO’s modification. This was unavoidable due to very small size of the Sample population. Conclusion: Thus this study had shown that the scintimetric evaluation of the skeletal hotspots in the Rheumatoid Arthritis Patients showed a definitive benign value. This could provide a firm base line value to assess the response to treatment and progression as well.","PeriodicalId":91304,"journal":{"name":"Journal of arthritis","volume":" ","pages":"1-3"},"PeriodicalIF":0.0,"publicationDate":"2017-01-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44645605","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Knee Osteoarthritis and Running: Is there any Evidence for Association? 膝关节骨性关节炎和跑步:有关联的证据吗?

Journal of arthritis Pub Date : 2017-01-01 DOI: 10.4172/2167-7921.1000257

M. Nair

{"title":"Knee Osteoarthritis and Running: Is there any Evidence for Association?","authors":"M. Nair","doi":"10.4172/2167-7921.1000257","DOIUrl":"https://doi.org/10.4172/2167-7921.1000257","url":null,"abstract":"The knee is the most common lower limb joint affected with Osteoarthritis (OA), which is a debilitating illness. The relationship between OA knee and running is not clear-cut, yet they are always associated with one another. The multitude of people suffering from lifestyle diseases is approaching epidemic proportions and Governments have to spend millions of dollars to manage these disorders. This has forced authorities to think about primary prevention rather than managing them after their onset. Slowly and steadily, the awareness about physical activity is increasing among the public. Due to this, there has been a surge in the number of people participating in activities for health reasons. The number of people taking part in running has also increased significantly. Many people resort to jogging and running because it is cost effective and convenient when compared to other types of exercises which need equipment or memberships. However, in addition to this, the concerns of damage to the knee joint have attracted the attention of clinicians and researchers. The common notion is that running damages the knees. Recent studies show that this concern is misplaced. The existing scientific evidence could not establish a link between the two, except in joints with a history of previous injury. Interestingly, results of some studies show that the chances of undergoing surgery for OA are less in runners. This article reviews the relevance of high-quality literature that looks at the link between running and the development of knee osteoarthritis.","PeriodicalId":91304,"journal":{"name":"Journal of arthritis","volume":"6 1","pages":"1-3"},"PeriodicalIF":0.0,"publicationDate":"2017-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.4172/2167-7921.1000257","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70836060","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Rheumatoid Arthritis Comorbidity Index (RACI): Development and Validation of a New Comorbidity Index for Rheumatoid Arthritis Patients 类风湿关节炎共病指数(RACI):一种新的类风湿关节炎共病指数的建立和验证

Journal of arthritis Pub Date : 2017-01-01 DOI: 10.4172/2167-7921.1000244

Y. ElMiedany, M. Elgaafary, S. Youssef, Samah Almedany, S. Bahlas, M. Hegazi

{"title":"Rheumatoid Arthritis Comorbidity Index (RACI): Development and Validation of a New Comorbidity Index for Rheumatoid Arthritis Patients","authors":"Y. ElMiedany, M. Elgaafary, S. Youssef, Samah Almedany, S. Bahlas, M. Hegazi","doi":"10.4172/2167-7921.1000244","DOIUrl":"https://doi.org/10.4172/2167-7921.1000244","url":null,"abstract":"Objective: Classify comorbidities with greatest impact on Rheumatoid Arthritis (RA) patients. Develop and validate a prospectively applicable comorbidity index for classifying RA patients according to their comorbid disorders which might impact alter their hospitalization and mortality risk. Methods: A weighted index which considers the number and impact of comorbid conditions was developed based on clinical registry of a cohort of 2029 patients with early RA monitored over 10-years. Logistic and Cox Regression analyses were implemented to estimate the risk of mortality. Regression coefficients were used to develop the index score. ROC curve for the invented index was used to evaluate the discriminating ability of the index and identify different cutoff values that can delineate patients at different stages for risk of death. Disease activity parameters were considered. Results: Comorbidities (18 conditions) were strongly associated with the 10-year death risk, and composed the RA-comorbidity index, include Cardiovascular (7 comorbidities), infection, osteoporotic fractures, falls risk, Depression/anxiety, functional status (HAQ >2), diabetes mellitus, steroid therapy >5 mg, DAS-28 >3.2), renal/liver/ lung disease and tumors. Considering the comorbidities number, the comorbidities adjusted relative risk were employed as weights to develop a weighted index. Validation using ROC curve revealed AUC of 97%. Conclusion: The RA-comorbidity index is a valid method for assessing risk of death in RA patients. The index enables the treating physician to include comorbidities valuation and treatment in their standard practice. It can be used to identify targets, predict resource utilization, and detect the potential targets for lowering high costs, by prospectively recognizing RA patients at high risk.","PeriodicalId":91304,"journal":{"name":"Journal of arthritis","volume":"6 1","pages":"1-8"},"PeriodicalIF":0.0,"publicationDate":"2017-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.4172/2167-7921.1000244","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70836365","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 6

The Common Accomplice of Pains, Moans, Groans: Imaging of Brown Tumors Debusted 疼痛，呻吟，呻吟的共同帮凶:棕色肿瘤的成像首次亮相

Journal of arthritis Pub Date : 2017-01-01 DOI: 10.4172/2167-7921.1000255

Meena Gl, M. Razak, Surbhi Gupta

{"title":"The Common Accomplice of Pains, Moans, Groans: Imaging of Brown Tumors Debusted","authors":"Meena Gl, M. Razak, Surbhi Gupta","doi":"10.4172/2167-7921.1000255","DOIUrl":"https://doi.org/10.4172/2167-7921.1000255","url":null,"abstract":"Brown tumors are focal bone lesions, caused by increased osteoclastic activity and fibroblastic proliferation, encountered in patients with uncontrolled hyperparathyroidism (HPT). They can be located in any part of the skeleton, but are most frequently encountered in the ribs, clavicles, extremities, and pelvic girdle. Clinically significant lesions in the craniofacial bones are rare Brown tumors are focal reactive osteolytic lesions caused by hyperparathyroidism (HPT) and represent the terminal stage of the hyperparathyroidism-dependent bone pathology. Nowadays, the manifestation of hyperparathyroidism with these lesions is extremely rare in developed countries, because of the early detection of the disease, using routine laboratory examination and early treatment of that. These benign lesions present similar radiologic findings as bone metastasis, which makes the diagnosis difficult Brown tumors are focal bone lesions, caused by increased osteoclastic activity and fibroblastic proliferation, encountered in patients with uncontrolled hyperparathyroidism (HPT). They can be located in any part of the skeleton, but are most frequently encountered in the ribs, clavicles, extremities, and pelvic girdle. Clinically significant lesions in the craniofacial bones are rare Brown tumors are focal reactive osteolytic lesions caused by hyperparathyroidism (HTP) and represent the terminal stage of the hyperparathyroidism-dependent bone pathology. Nowadays, the manifestation of hyperparathyroidism with these lesions is extremely rare in developed countries, because of the early detection of the disease, using routine laboratory examination and early treatment of that. These benign lesions present similar radiologic findings as bone metastasis, which makes the diagnosis difficult.","PeriodicalId":91304,"journal":{"name":"Journal of arthritis","volume":"6 1","pages":"1-4"},"PeriodicalIF":0.0,"publicationDate":"2017-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.4172/2167-7921.1000255","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70836456","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Detection of Septic Arthritis using Meta Heuristic Algorithms 利用元启发式算法检测脓毒性关节炎

Journal of arthritis Pub Date : 2017-01-01 DOI: 10.4172/2167-7921.1000259

Jobin Christ Mc, A. Lakshminarayanan, R. Krishnan

引用次数: 4

A Novel Rat Model of Ankle Osteoarthritis Induced by the Application of Monoiodoacetate 单碘乙酸酯致大鼠踝关节骨关节炎模型的建立

Journal of arthritis Pub Date : 2017-01-01 DOI: 10.4172/2167-7921.1000260

S. Jimbo, Y. Terashima, T. Takebayashi, A. Teramoto, I. Ogon, Kota Watanabe, Tatsuya Sato, N. Ichise, N. Tohse, T. Yamashita

{"title":"A Novel Rat Model of Ankle Osteoarthritis Induced by the Application of Monoiodoacetate","authors":"S. Jimbo, Y. Terashima, T. Takebayashi, A. Teramoto, I. Ogon, Kota Watanabe, Tatsuya Sato, N. Ichise, N. Tohse, T. Yamashita","doi":"10.4172/2167-7921.1000260","DOIUrl":"https://doi.org/10.4172/2167-7921.1000260","url":null,"abstract":"Although ankle osteoarthritis is a common human joint disease, the etiological mechanisms underlying the associated pain remain unknown. We developed a new rat model of ankle osteoarthritis (OA) induced by monoiodoacetate (MIA) and evaluated the behavioral and histological characteristics of these animals. 60 male Sprague-Dawley rats were divided into three experimental groups of 20 rats. OA was induced by injecting the metabolic inhibitor MIA (1 mg/30 μl) into the tibiotarsal joint of the right hind paw on two consecutive days (MIA2 group) or single day (MIA1 group). Saline was injected into sham rats using the same protocol (sham group). We examined ankle swelling, range of motion, and stride length. We also assessed pain related behavior by observing the mechanical and thermal withdrawal responses. Rats were sacrificed 28 days after MIA/saline injection, and the right ankle joints were removed. Ankle sections were stained with safranin-O fast green, and histopathological changes were observed and scored. Both MIA groups exhibited significant increase in the ankle anteroposterior and transverse diameters (i.e., swelling) on days 7, 14, 21, and 28 post-injection relative to sham, as well as significantly decrease ROMs of the ankle. MIA2 rats additionally had a significantly shorter stride than did sham rats. MIA2 rats also exhibited an increased mechanical response frequency to the von Frey hair 4 g, and 6g tests, compared with sham rats, whereas MIA1 rats did not differ significantly from sham rats. Both MIA2 and MIA1 rats exhibited significantly reduced thermal latency in the hind paw relative to the sham group on day 28 post-injection. Histologically, the both MIA groups had a significantly higher score on day 28 post-injection, compared with the sham rats. MIA2 rats also exhibited more histological evidence of cartilage damage and abnormal medial tibia morphology, compared to MIA1 and sham rats.","PeriodicalId":91304,"journal":{"name":"Journal of arthritis","volume":"6 1","pages":"1-5"},"PeriodicalIF":0.0,"publicationDate":"2017-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.4172/2167-7921.1000260","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70836327","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 4

Personalized Medicine for Metal on Metal Hip Resurfacing: Predictors for the 10 Years Success of the Birmingham Hip Resurfacing 金属髋关节置换术的个性化医疗:伯明翰髋关节置换术10年成功的预测因素

Journal of arthritis Pub Date : 2017-01-01 DOI: 10.4172/2167-7921.1000228

J. Kuiper, P. Lee, P. Heaton, A. Qureshi, J. Richardson

{"title":"Personalized Medicine for Metal on Metal Hip Resurfacing: Predictors for the 10 Years Success of the Birmingham Hip Resurfacing","authors":"J. Kuiper, P. Lee, P. Heaton, A. Qureshi, J. Richardson","doi":"10.4172/2167-7921.1000228","DOIUrl":"https://doi.org/10.4172/2167-7921.1000228","url":null,"abstract":"Background: Metal-on-metal hip resurfacing arthroplasty was introduced to preserve patients’ bone and facilitate revision surgery. This prospective cohort study aims to determine a prognostic model (OsBHR) to predict which patient and surgeon related factors predict better long term implant survival for the Birmingham Hip Resurfacing (BHR). Methods: Between 1997 and 2002, details of 4490 patients (4945 hips) treated by hip resurfacing arthroplasty using the BHR prosthesis were entered in a prospective international registry and available for analysis. Implant survival was determined using the Kaplan-Meier estimator and a shared frailty proportional hazard model was used to determine predictors of implant revision. Results: prognostic equation suggested a minimum diameter of 50 mm should be used for male and 52 mm for female patients to ensure a minimum 10-year survival rate of 95% for in procedures performed by an average surgeon. Conclusion: Implant survival at ten years and beyond strongly depends on component size and gender, varies between surgeons but is little affected by patient age. The OsBHR predictor allows a personalized estimated survival at ten years based on pre-operative variables.","PeriodicalId":91304,"journal":{"name":"Journal of arthritis","volume":"6 1","pages":"1-7"},"PeriodicalIF":0.0,"publicationDate":"2017-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70836283","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Case Report: SPECT/CT as the New Diagnostic Tool for Specific Wrist Pathology. 病例报告:SPECT/CT作为特殊手腕病理的新诊断工具。

Journal of arthritis Pub Date : 2017-01-01 Epub Date: 2017-07-21 DOI: 10.4172/2167-7921.1000246

Linde Musters, M Ten Broek, G A Kraan

{"title":"Case Report: SPECT/CT as the New Diagnostic Tool for Specific Wrist Pathology.","authors":"Linde Musters, M Ten Broek, G A Kraan","doi":"10.4172/2167-7921.1000246","DOIUrl":"https://doi.org/10.4172/2167-7921.1000246","url":null,"abstract":"Introduction: Single photon emission computed tomography has been introduced as a promising new diagnostic tool in orthopaedic pathology since the early 90'. Computed tomography, the combined with SPECT, gives insight in the specific sight of wrist pathology. Literature already supports introduction of SPECT/CT in wrist pathology, but clinical application is lagging.Case report: A 40yr old patient reported first in 2004 with persisting pain after a right distal radius fracture. Several diagnostics and operative interventions were performed, all unsuccessful. Because of the persisting pain a SPECT-CT was performed which showed a cyst in the hamate bone, which was successfully enucleated. The patient was finally pain free at recent follow-up. With a QDash-score of 43 and a PRW (H) E-DLV-score of 58/150.Discussion: In this case report, SPECT/CT proved a very sensitive diagnostic tool for specific pathology of the wrist. It offered precise localisation and thereby the clinically suspected diagnosis was confirmed and the patient successfully treated.","PeriodicalId":91304,"journal":{"name":"Journal of arthritis","volume":"6 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2017-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.4172/2167-7921.1000246","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36068017","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Quantification of VEGF and Screening of Transcription Factor HIF-1α in Synovial Fluid of Polyarthritic Patients: Targets for Potential Anti-angiogenic Molecules 多发性关节炎患者滑液中VEGF的定量和转录因子HIF-1α的筛选:潜在的抗血管生成分子靶点

Journal of arthritis Pub Date : 2017-01-01 DOI: 10.4172/2167-7921.1000229

Shankar Jayarama, Shivakumar Subanna, Barathi Paramahamsa Salimath, J. Krishnamurthy

{"title":"Quantification of VEGF and Screening of Transcription Factor HIF-1α in Synovial Fluid of Polyarthritic Patients: Targets for Potential Anti-angiogenic Molecules","authors":"Shankar Jayarama, Shivakumar Subanna, Barathi Paramahamsa Salimath, J. Krishnamurthy","doi":"10.4172/2167-7921.1000229","DOIUrl":"https://doi.org/10.4172/2167-7921.1000229","url":null,"abstract":"Rheumatoid arthritis (RA) is a polyarticular inflammatory autoimmune disease and osteoarthritis (OA) is an inflammatory degenerative disease of the articular cartilage. The current study efforts have been made to understand the relationship between the angiogenic genes VEGF, its regulator HIF-1α and MVD in RA and OA. The level of VEGF in serum and synovial fluid was increased in both RA and OA, but the levels were slightly more in cases of RA compared to that of OA. A corresponding increase in expression of HIF-1α and MVD counts was also noted in both conditions. Similar to VEGF levels, the expression of HIF-1α , MVD and CD-31 counts was higher among RA patients. These results thus indicate that there is a significant association between the angiogenic peptide VEGF in serum and synovial fluids, expression levels of transcription factor HIF-1α and microvessel density in the synovium of polyarthritic patients. The increased expression and regulation of VEGF, HIF-1alpha and MVD in these chronic inflammatory conditions are not only early indicators but also potential targets for antiangiogenic factors in the therapeutics of novel drugs for these smoldering conditions.","PeriodicalId":91304,"journal":{"name":"Journal of arthritis","volume":"6 1","pages":"1-5"},"PeriodicalIF":0.0,"publicationDate":"2017-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70836316","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0