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Cellular breakdown in the lungs: Brief Report of Advanced and TraditionalTreatments and Diagnosis 肺细胞破裂:先进和传统治疗和诊断的简要报告
Archives in cancer research Pub Date : 2021-01-01 DOI: 10.36648/2254-6081.21.9.E002
K. Petrak
{"title":"Cellular breakdown in the lungs: Brief Report of Advanced and TraditionalTreatments and Diagnosis","authors":"K. Petrak","doi":"10.36648/2254-6081.21.9.E002","DOIUrl":"https://doi.org/10.36648/2254-6081.21.9.E002","url":null,"abstract":"Cellular breakdown in the lungs is an uncontrolled development of lung cells that is lead to shape a tumor. Over 20% of complete malignant growth passing is because of cellular breakdown in the lungs. There are basically two kinds of compelling medicines accessible viz. customary and advance. Every treatment has their upsides and downsides, however the development and most recent treatment has high ground just as compelling outcomes contrasted with the customary one. Both Traditional chemotherapy and radiotherapy restrictedly affect advance phase of disease. This audit gives similar record of customary and advances in cellular breakdown in the lungs treatment.","PeriodicalId":91204,"journal":{"name":"Archives in cancer research","volume":"9 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69702613","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Multimodality Imaging Based Treatment Volume Definition for Reirradiation of Recurrent Small Cell Lung Cancer (SCLC) 基于多模态成像的复发性小细胞肺癌再照射治疗体积定义
Archives in cancer research Pub Date : 2021-01-01 DOI: 10.36648/2254-6081.21.9.004
O. Sager, S. Demiral, F. Dinçoğlan, M. Beyzadeoğlu
{"title":"Multimodality Imaging Based Treatment Volume Definition for Reirradiation of Recurrent Small Cell Lung Cancer (SCLC)","authors":"O. Sager, S. Demiral, F. Dinçoğlan, M. Beyzadeoğlu","doi":"10.36648/2254-6081.21.9.004","DOIUrl":"https://doi.org/10.36648/2254-6081.21.9.004","url":null,"abstract":"Objective: Small cell lung cancer (SCLC) may be considered as a major health concern as a leading cause of cancer related mortality worldwide. Despite intensive management, SCLC may follow an aggressive disease course with recurrent and/ or metastatic disease in a considerable proportion of the patients. Herein, we assess multimodality imaging based treatment volume definition for reirradiation of recurrent SCLC. Literature Review: Definition of treatment volume by multimodality imaging with incorporation of positron emission tomography (PET) or by computed tomography (CT)-simulation images only has been evaluated with comparative analysis for patients reirradiated for recurrent SCLC. Results: A multidisciplinary team of experts from surgery, medical oncology, radiation oncology, and pulmonology has been involved in individualized patient evaluation. Decision making for reirradiation of patients with recurrent SCLC has been performed after comprehensive assessment considering the lesion size, localization and association with critical structures, previously administered treatments at initial diagnosis, and time interval from initial RT. Treatment volume determination by CT-only imaging and by CT-PET fusion based imaging has been assessed with comparative analysis. Ground truth target volume has been found to be identical with treatment volume determination by CT-PET fusion based imaging as the primary result of this study. Conclusion: Incorporation of PET in RT planning process may be considered for patients receiving reirradiation for recurrent SCLC. Clearly, further investigation is required to shed light on this issue.","PeriodicalId":91204,"journal":{"name":"Archives in cancer research","volume":"5 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69702042","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Novel Strategy for Colorectal Liver Cancer- Hepatocyte Growth Factor EstimationConcept 结直肠癌的新策略-肝细胞生长因子评估概念
Archives in cancer research Pub Date : 2021-01-01 DOI: 10.36648/2254-6081.21.9.002
G. Chhabra, N. Puri
{"title":"Novel Strategy for Colorectal Liver Cancer- Hepatocyte Growth Factor EstimationConcept","authors":"G. Chhabra, N. Puri","doi":"10.36648/2254-6081.21.9.002","DOIUrl":"https://doi.org/10.36648/2254-6081.21.9.002","url":null,"abstract":"Colorectal disease is the third most regular epithelial threataround the world. Sooner or later in the characteristiccourse of patients with this illness, up to half will fostermetastasis to the liver, i.e., Colorectal Liver Metastasis(CLM), which addresses quite possibly the most well-knowndangers to life. An assortment of remedial ways to deal withtreat this hazardous sickness have been endeavored thathave now brought about the acknowledgment of a forcefultechnique in any event, for cutting edge cases. Be that as itmay, the careful signs for resection of coordinatedmetastases and the ideal planning of hepatectomy are asyet dubious and generally discussed. In the current survey,chemotherapeutic procedures including as of late createdsystems or potentially hepatectomy are proposed puttogether with respect to the clinical information as well ason natural ideas in which chemotherapy causes hepatocytedevelopment factor (HGF)- related epithelial mesenchymalprogress (EMT).","PeriodicalId":91204,"journal":{"name":"Archives in cancer research","volume":"9 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69701995","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Clinical Challenges to Current Molecularly Targeted Therapies in CellularBreakdown in the Lungs 当前分子靶向治疗肺细胞分解的临床挑战
Archives in cancer research Pub Date : 2021-01-01 DOI: 10.36648/2254-6081.21.9.001
S. Osada, S. Matsui, Yoshiyuki Sasaki
{"title":"Clinical Challenges to Current Molecularly Targeted Therapies in CellularBreakdown in the Lungs","authors":"S. Osada, S. Matsui, Yoshiyuki Sasaki","doi":"10.36648/2254-6081.21.9.001","DOIUrl":"https://doi.org/10.36648/2254-6081.21.9.001","url":null,"abstract":"The Cellular breakdown in the lungs is hard to treat with ahelpless guess and a long term endurance of 15%. Currentatomically focused on treatments are at first viable in non-little cell cellular breakdown in the lungs (NSCLC) patients;be that as it may, they are tormented with troublesincluding instigatedobstruction and little remediallyresponsive populaces. This scaled down audit portrays theinstrument of protection from a few atomically focused ontreatments which are at present being utilized to treatNSCLC. The significant targets talked about are c-Met, EGFR,HER2, ALK, VEGFR, and BRAF. The original tyrosine kinaseinhibitors (TKIs) brought about obstruction; nonetheless,second and third era TKIs are being created, which are forthe most part more useful and can possibly treat NSCLCpatients with protection from original TKIs. Blendtreatments could likewise be compelling in forestalling TKIopposition in NSCLC patients.","PeriodicalId":91204,"journal":{"name":"Archives in cancer research","volume":"9 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69702258","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Reduction of Tumor Vascularity and Aid Excision using Endovascular Embolization 血管内栓塞术减少肿瘤血管及辅助切除
Archives in cancer research Pub Date : 2021-01-01 DOI: 10.36648/2254-6081.21.9.E001
A. Heidari
{"title":"Reduction of Tumor Vascularity and Aid Excision using Endovascular Embolization","authors":"A. Heidari","doi":"10.36648/2254-6081.21.9.E001","DOIUrl":"https://doi.org/10.36648/2254-6081.21.9.E001","url":null,"abstract":"Fresh fruits are considered as a healthy source of water soluble vitamins. Vitamins are needed for metabolic reactions, their deficiency or increased intake lead to different irregularities in normal metabolism. Our work aimed to determine some different types of vitamin B as B1, B6, B2, B9 and B17 and applications of different methods of extracting and analyzing them by HPLC then loading them on chitosan nanoparticles (CSNPs) to study its biological applications and cytotoxicity on different cell lines. HPLC analysis of acid hydrolysis samples showed that thiamine (B1) was found in range of 88.13-96.66 %, riboflavin (B2) was 95 - 96.216 %, pyridoxine (B6) was 95.22 - 100 %, folate (B9) 95.6-96.94 % while amygdalin (B17) was 94.975-96.66 %. After loading vitamins with chitosan, the results showed cytotoxic activities of Vitamins B1, B2, B6, B9 and B17 as these extracted vitamins were tested against different cancerous and normal cell lines. Vitamin B6 nanoparticles showed the best cytotoxic effect on different cancerous cell lines as Hepatocelluar carcinoma (HePG2), Mammary gland Breast cancer (MCF-7) and Epitheliod Carcinoma Cervix cancer (Hela) and it can be considered as a safe compound on normal cell as normal human lung fibroblast cell line (WI-38).","PeriodicalId":91204,"journal":{"name":"Archives in cancer research","volume":"9 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69702809","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Evaluation of Antimicrobial and Anticancer Activity of Lactococcus garvieae Derived Bacteriocin garvieae乳球菌衍生细菌素的抗菌和抗癌活性评价
Archives in cancer research Pub Date : 2021-01-01 DOI: 10.36648/2254-6081.21.9.006
S. Kaliwal, S. Tendulkar, Aishwarya Hattiholi
{"title":"Evaluation of Antimicrobial and Anticancer Activity of Lactococcus garvieae Derived Bacteriocin","authors":"S. Kaliwal, S. Tendulkar, Aishwarya Hattiholi","doi":"10.36648/2254-6081.21.9.006","DOIUrl":"https://doi.org/10.36648/2254-6081.21.9.006","url":null,"abstract":"Lactic acid bacteria (Lac B) are a prominent class of microorganisms that are capable of producing a variety of antimicrobial peptides or bacteriocins, which have inhibitory action on closely or far related organisms. In this study, we isolate and characterize bacteriocin from Lactococcus garvieae which, after dialysis showed significant activity against some bacterial and fungal strains, as well as anticancer activity against HT29 (Colorectal adenocarcinoma) cell lines.","PeriodicalId":91204,"journal":{"name":"Archives in cancer research","volume":"9 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69702232","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Overview of the Teartments of Esophageal, Liver, Pancreas and Rectal Cancers 食管癌、肝癌、胰腺癌和直肠癌的撕裂综述
Archives in cancer research Pub Date : 2021-01-01 DOI: 10.36648/2254-6081.21.S5.005
B. Sharma, Shanetia S. Avinger, S. Jabbour
{"title":"Overview of the Teartments of Esophageal, Liver, Pancreas and Rectal Cancers","authors":"B. Sharma, Shanetia S. Avinger, S. Jabbour","doi":"10.36648/2254-6081.21.S5.005","DOIUrl":"https://doi.org/10.36648/2254-6081.21.S5.005","url":null,"abstract":"","PeriodicalId":91204,"journal":{"name":"Archives in cancer research","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69703055","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Overview of Metastasis Suppressor KAI1/CD82 in Different Cancers 转移抑制因子KAI1/CD82在不同肿瘤中的研究进展
Archives in cancer research Pub Date : 2021-01-01 DOI: 10.36648/2254-6081.21.9.E003
eep Misra
{"title":"Overview of Metastasis Suppressor KAI1/CD82 in Different Cancers","authors":"eep Misra","doi":"10.36648/2254-6081.21.9.E003","DOIUrl":"https://doi.org/10.36648/2254-6081.21.9.E003","url":null,"abstract":"","PeriodicalId":91204,"journal":{"name":"Archives in cancer research","volume":"9 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69702668","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Phyllodes Tumor Arising In The Ectopic Breast Tissue Of Axilla- A Rare Pathology 发生于腋窝异位乳腺组织的叶状瘤——一种罕见的病理
Archives in cancer research Pub Date : 2020-01-01 DOI: 10.35248/2576-1447.20.5.105
Rabbia Zubair
{"title":"Phyllodes Tumor Arising In The Ectopic Breast Tissue Of Axilla- A Rare Pathology","authors":"Rabbia Zubair","doi":"10.35248/2576-1447.20.5.105","DOIUrl":"https://doi.org/10.35248/2576-1447.20.5.105","url":null,"abstract":"Benign and malignant pathology can develop in ectopic axillary breast tissue (accessory breast), such as fibroadenoma, phyllodes tumor and breast cancer. I present a rare case of 21-years old married female with bilateral breast lumps and a swelling in right axilla. On clinical examination, the impression of bilateral fibroadenomas and right sided accessory breast with a round mobile 6x5cm swelling in it, which appears like a giant fibroadenoma. Ultrasonography supported the clinical diagnosis. Case was discussed with the patient and family and excision of bilateral fibroadenoma along with excision of right sided accessory lump was planned. Surgery was carried out under general anaesthesia. Bilateral fibroadenomas were excised by circumareolar incisions and accessory breast was excised through an elliptical incision. Histopathology was sent which later revealed that the mobile mass in right accessory breast was composed of epithelial component forming ducts and in areas forming leaf like configuration. Stroma showing mild to moderate increase in cellularity. Focal areas showing fibroblastic proliferation and foreign body type giant cells. The overlying skin show unremarkable epidermis and dermis. The above mentioned findings were suggestive of a benign phyllodes tumor in right accessory breast.","PeriodicalId":91204,"journal":{"name":"Archives in cancer research","volume":"8 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70015981","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Seminal Vesicle Cystadenoma Presenting as a Giant Cystic Abdominal Mass: Case Report and Literature Review 精囊囊腺瘤表现为巨大的腹腔囊性肿块:病例报告及文献复习
Archives in cancer research Pub Date : 2020-01-01 DOI: 10.36648/2254-6081.8.1.5
M. Achraf
{"title":"Seminal Vesicle Cystadenoma Presenting as a Giant Cystic Abdominal Mass: Case Report and Literature Review","authors":"M. Achraf","doi":"10.36648/2254-6081.8.1.5","DOIUrl":"https://doi.org/10.36648/2254-6081.8.1.5","url":null,"abstract":"Benign primary tumors including cystadenomas are the rarest tumors of the seminal vesicles. All around only 22 cases of cystadenoma of the SV have been reported since 1944. The diagnosis is typically made on final pathology since clinical findings and imaging techniques are non-specific. The only curative treatment is surgical resection, either by open or laparoscopic surgery. In our work, we report the case of a giant seminal vesicle cystadenoma in an 80 yearsold patient in whom the huge abdominal cystic mass was suspicious to be related to a malignant process since it presented intimate contact with pelvic structures. Pathological examination after excision of the mass has confirmed the nature of the huge mass as a benign cystadenoma of the seminal vesicle","PeriodicalId":91204,"journal":{"name":"Archives in cancer research","volume":"8 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69703766","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
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