Boletín médico del Hospital Infantil de México最新文献

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Comparison between the KARVI scale and the Child Development Evaluation test (EDI) as a screening tool for suspected neurodevelopmental delay. 将 KARVI 量表与儿童发育评估测试 (EDI) 作为筛查疑似神经发育迟缓的工具进行比较。
IF 0.9
Boletín médico del Hospital Infantil de México Pub Date : 2024-01-01 DOI: 10.24875/BMHIM.23000062
Carolina Tovar-Moreno, Miguel A Karlis-Rangel, Susana A Villarreal-Guerra, Fernanda P García-Ayón, Jesús Santos-Guzmán, Belinda Carrión-Chavarría
{"title":"Comparison between the KARVI scale and the Child Development Evaluation test (EDI) as a screening tool for suspected neurodevelopmental delay.","authors":"Carolina Tovar-Moreno, Miguel A Karlis-Rangel, Susana A Villarreal-Guerra, Fernanda P García-Ayón, Jesús Santos-Guzmán, Belinda Carrión-Chavarría","doi":"10.24875/BMHIM.23000062","DOIUrl":"10.24875/BMHIM.23000062","url":null,"abstract":"<p><strong>Background: </strong>Early detection of suspected neurodevelopmental delay allows for timely diagnosis and appropriate intervention, for which numerous screening tests have been developed. However, most are complex and impractical for health-care workers at the community level. This study aimed to validate the KARVI scale in the neurodevelopment assessment of children under 1 year of age.</p><p><strong>Methods: </strong>We conducted an observational, longitudinal, comparative, inferential, and prospective study. Healthy children without risk factors for developing neurodevelopmental delay from 0 to 12 months of age were evaluated remotely using the Zoom<sup>®</sup> application. The Child Development Evaluation Test and the KARVI scale were applied once a month for four consecutive months.</p><p><strong>Results: </strong>Fifty individuals were analyzed, with a predominance of males in 52%. Adequate percentages for a screening test were obtained in the first evaluation with a sensitivity of 70% (confidence interval [CI] 95% 34.75-93.33) and a specificity of 75% (CI 95% 58.8-87.31), and in the fourth evaluation with a sensitivity of 100% (CI 95% 29.4-100) and a specificity of 78.72% (CI 95% 64.34-89.3), being significant in both evaluations (p = 0.007 and p = 0.001, respectively).</p><p><strong>Conclusions: </strong>The KARVI scale has the elements to be an effective screening test for suspected neurodevelopmental delay, but more extensive studies are needed to obtain more reliable results.</p>","PeriodicalId":9103,"journal":{"name":"Boletín médico del Hospital Infantil de México","volume":"81 1","pages":"36-43"},"PeriodicalIF":0.9,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140179319","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Association of oropharyngeal colostrum administration with decreased inflammatory indices in premature newborns weighing less than 1500 g. 口咽初乳与体重不足 1500 克的早产新生儿炎症指数下降的关系
IF 0.6
Boletín médico del Hospital Infantil de México Pub Date : 2024-01-01 DOI: 10.24875/BMHIM.23000048
Guadalupe Gómez-Rodríguez, Juan L Moreno-Saldaña, Evaldo J Rodríguez-Mejía, Marco A Olvera-Olvera
{"title":"Association of oropharyngeal colostrum administration with decreased inflammatory indices in premature newborns weighing less than 1500 g.","authors":"Guadalupe Gómez-Rodríguez, Juan L Moreno-Saldaña, Evaldo J Rodríguez-Mejía, Marco A Olvera-Olvera","doi":"10.24875/BMHIM.23000048","DOIUrl":"10.24875/BMHIM.23000048","url":null,"abstract":"<p><strong>Background: </strong>The administration of colostrum through its absorption at the oropharyngeal level stimulates the mucosa-associated lymphoid tissue, providing a local immunological protection barrier. The study aimed to investigate the association of oropharyngeal colostrum administration with the reduction of inflammatory indices.</p><p><strong>Materials and methods: </strong>This was an observational, ambispective, analytical study of newborns < 32 weeks of gestation at risk of sepsis. Oropharyngeal colostrum was administered at 0.2 mL every 4 h for 5 days. Inflammatory indices were analyzed. Statistical analysis included frequencies, percentages, mean and Standard deviation, contingency coefficient, and Kolmogorov-Smirnov test for the distribution curve of the numerical data.</p><p><strong>Results: </strong>There were 50 patients, 33 (66%) female and 17 (34%) male, with a median gestational age of 30-31 weeks (95% confidence interval [CI]). Nineteen patients had sepsis. A lower positivity rate in C-reactive protein was found, with a median of 0.5-0.6 (95% CI) at 5 days of colostrum administration versus 0.5-1.1 (95% CI) as the initial C-reactive protein. Analysis with χ<sup>2</sup> yielded a p = 0.13, and the contingency coefficient showed a p = 0.196, indicating an association.</p><p><strong>Conclusion: </strong>Oropharyngeal colostrum administration was associated with a lower C-reactive protein positivity rate and clinical improvement in premature newborns at risk of sepsis.</p>","PeriodicalId":9103,"journal":{"name":"Boletín médico del Hospital Infantil de México","volume":"81 3","pages":"170-175"},"PeriodicalIF":0.6,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141466160","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Analysis of the changes in the management of preterm newborns born in a Spanish third-level hospital in the past 10 years. 过去 10 年西班牙一家三级医院早产新生儿管理变化分析。
IF 0.9
Boletín médico del Hospital Infantil de México Pub Date : 2024-01-01 DOI: 10.24875/BMHIM.23000093
María Santiago-Souto, Rafael García-Mozo, Marta Costa-Romero
{"title":"Analysis of the changes in the management of preterm newborns born in a Spanish third-level hospital in the past 10 years.","authors":"María Santiago-Souto, Rafael García-Mozo, Marta Costa-Romero","doi":"10.24875/BMHIM.23000093","DOIUrl":"https://doi.org/10.24875/BMHIM.23000093","url":null,"abstract":"<p><strong>Background: </strong>Preterm newborns require the use of the best and most current strategies to treat and prevent both acute pathology and associated sequelae. This study aimed to compare the differences in the management of preterm newborns over 10 years in a tertiary hospital in Spain and its impact on height, weight, and neurological development in the medium term.</p><p><strong>Methods: </strong>We conducted a retrospective, observational, and analytical study examining the management and clinical variables in preterm newborns under 32 weeks of gestational age who were born in our hospital in 2011 and 2021.</p><p><strong>Results: </strong>Twenty-six newborns were included in the study. Significant differences in magnesium sulfate use, continuous positive airway pressure immediately after birth, and non-invasive mechanical ventilation during hospitalization were observed. Differences were found in the use of parenteral nutrition and the timing of initiation of enteral feeding. We did not observe differences in the neurological or weight evolution in the medium term.</p><p><strong>Conclusions: </strong>Significant differences in managing preterm newborns in these 10 years were observed. Lower mortality and alterations in central nervous system ultrasound and, significantly, less growth retardation during admission in 2021 have been observed; however, it does not manifest with improvement in long-term somatometrics or neurological prognosis.</p>","PeriodicalId":9103,"journal":{"name":"Boletín médico del Hospital Infantil de México","volume":"81 1","pages":"16-22"},"PeriodicalIF":0.9,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140179317","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Drugs and natural products for the treatment of COVID-19 during 2020, the first year of the pandemic. 2020 年,即大流行的第一年,用于治疗 COVID-19 的药物和天然产品。
IF 0.9
Boletín médico del Hospital Infantil de México Pub Date : 2024-01-01 DOI: 10.24875/BMHIM.23000016
Elia G Jaimes-Castelán, Claudia González-Espinosa, Gil A Magos-Guerrero, Isabel Arrieta-Cruz, Manuel Jiménez-Estrada, Ricardo Reyes-Chilpa, Jorge I Castillo-Arellano
{"title":"Drugs and natural products for the treatment of COVID-19 during 2020, the first year of the pandemic.","authors":"Elia G Jaimes-Castelán, Claudia González-Espinosa, Gil A Magos-Guerrero, Isabel Arrieta-Cruz, Manuel Jiménez-Estrada, Ricardo Reyes-Chilpa, Jorge I Castillo-Arellano","doi":"10.24875/BMHIM.23000016","DOIUrl":"https://doi.org/10.24875/BMHIM.23000016","url":null,"abstract":"<p><p>This work aimed to show which treatments showed efficacy against coronavirus disease 2019 (COVID-19); therefore, the results of 37 clinical trials started in 2020 and completed in 2021 are reviewed and discussed here. These were selected from databases, excluding vaccines, computational studies, in silico, in vitro, and those with hyperimmune sera from recovered patients. We found 34 drugs, one vitamin, and one herbal remedy with pharmacological activity against symptomatic COVID-19. They reduced mortality, disease progression, or recovery time. For each treatment, the identifier and type of trial, the severity of the disease, the sponsor, the country where the trial was conducted, and the trial results are presented. The drugs were classified according to their mechanism of action. Several drugs that reduced mortality also reduced inflammation in the most severe cases. These include some that are not considered anti-inflammatory, such as Aviptadil, pyridostigmine bromide, anakinra, imatinib, baricitinib, and bevacizumab, as well as the combination of ivermectin, aspirin, dexamethasone, and enoxaparin. Nigella sativa seeds with honey have also been reported to have therapeutic activity. On the other hand, tofacitinib, novaferon with ritonavir, and lopinavir were also effective, as well as in combination with antiviral therapies such as danoprevir with ritonavir. The natural products colchicine and Vitamin D3 were only effective in patients with mild-to-moderate COVID-19, as was hydroxychloroquine. Drug repositioning has been the main tool in the search for effective therapies by expanding the pharmacological options available to patients.</p>","PeriodicalId":9103,"journal":{"name":"Boletín médico del Hospital Infantil de México","volume":"81 1","pages":"53-72"},"PeriodicalIF":0.9,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140179377","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Prevalence of secondary arterial hypertension in patients with acute renal failure in a secondary-level pediatric hospital in Northwestern Mexico. 墨西哥西北部一家二级儿科医院急性肾功能衰竭患者继发性动脉高血压的患病率。
IF 0.6
Boletín médico del Hospital Infantil de México Pub Date : 2024-01-01 DOI: 10.24875/BMHIM.23000013
Humberto Peña-Guevara, Iyali M Corrales-Cambero, Saúl Cañizales-Muñoz
{"title":"Prevalence of secondary arterial hypertension in patients with acute renal failure in a secondary-level pediatric hospital in Northwestern Mexico.","authors":"Humberto Peña-Guevara, Iyali M Corrales-Cambero, Saúl Cañizales-Muñoz","doi":"10.24875/BMHIM.23000013","DOIUrl":"10.24875/BMHIM.23000013","url":null,"abstract":"<p><strong>Background: </strong>The worldwide prevalence of arterial hypertension in pediatric patients is 3.5%, and it has repercussions at renal, cardiovascular, neurological, and lifestyle levels. This study aimed to estimate the prevalence of arterial hypertension, mortality, and follow-up in patients with acute renal failure in the nephrology outpatient clinic at a second-level hospital in Northwestern Mexico.</p><p><strong>Methods: </strong>We conducted a descriptive, retrospective, and observational study. Men and women aged 1-18 years diagnosed with acute kidney injury were analyzed from January 1, 2012, to December 31, 2021. The medical and electronic records of the candidate patients were analyzed, and nutritional data, laboratory analysis, most frequent etiology, and follow-up in the pediatric nephrology clinic were collected. Those with exacerbated chronic kidney disease and previous diagnosis of high blood pressure were excluded.</p><p><strong>Results: </strong>One hundred and seventy-four patients were evaluated, and only 40 were eligible for the study (22.98%), predominantly males with a mean age of 9.9 years. The degree of arterial hypertension was 50% for grade I and 50% for grade II (p = 0.007); the mortality rate was 32%. One hundred percent of hypertension cases were controlled at 6 months after discharge (p = 0.000080).</p><p><strong>Conclusions: </strong>Our results were similar to those reported in other studies. Follow-up and early detection of arterial hypertension in children need to be strengthened.</p>","PeriodicalId":9103,"journal":{"name":"Boletín médico del Hospital Infantil de México","volume":"81 3","pages":"151-161"},"PeriodicalIF":0.6,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141466163","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Vascular malformations in pediatric patients: 10-year experience of a vascular anomalies clinic. 儿科血管畸形:血管畸形诊所的十年经验。
IF 0.6
Boletín médico del Hospital Infantil de México Pub Date : 2024-01-01 DOI: 10.24875/BMHIM.23000144
Sofía Valdés-Loperena, Adolfo E Lizardo-Rodríguez, Carlos G Hinojosa-Gutiérrez, Max A Bernal-Moreno, Gerardo A Montejo-Ruiz, Manuel Guerrero-Hernández, Jaime Shalkow-Klincovstein, Rodrigo Díaz-Machorro, Daniel Hernández-Arrazola, José M Palacios-Acosta, Oscar Colín-Martínez, Gerardo Fernández-Sobrino, Ana M Borbolla-Pertierra, Carola Durán-Mc Kinster, María Teresa García-Romero
{"title":"Vascular malformations in pediatric patients: 10-year experience of a vascular anomalies clinic.","authors":"Sofía Valdés-Loperena, Adolfo E Lizardo-Rodríguez, Carlos G Hinojosa-Gutiérrez, Max A Bernal-Moreno, Gerardo A Montejo-Ruiz, Manuel Guerrero-Hernández, Jaime Shalkow-Klincovstein, Rodrigo Díaz-Machorro, Daniel Hernández-Arrazola, José M Palacios-Acosta, Oscar Colín-Martínez, Gerardo Fernández-Sobrino, Ana M Borbolla-Pertierra, Carola Durán-Mc Kinster, María Teresa García-Romero","doi":"10.24875/BMHIM.23000144","DOIUrl":"10.24875/BMHIM.23000144","url":null,"abstract":"<p><strong>Background: </strong>Vascular malformations (VaMs) are caused by errors in vascular morphogenesis. Diagnosis and treatment can be complex. Few specialized centers care for these patients, and limited literature exists regarding their characteristics and clinical course. The vascular anomalies clinic (VAC) at the Instituto Nacional de Pediatría (National Institute for Pediatrics) is a multidisciplinary team and has been a reference center for patients with VaMs since 2012. We sought to describe the characteristics of patients cared for at the VAC, types of VaMs, treatments used, and clinical course.</p><p><strong>Methods: </strong>This was a descriptive, observational, retrospective, and cross-sectional study conducted from 2012 to 2022.</p><p><strong>Results: </strong>We included 435 patients with VaMs; the median age of presentation was 1 month. The most frequent signs and symptoms were increased volume (97.2%), superficial color change (65.5%), and pain (43.3%). The most common VaMs were lymphatic (36.7%) and venolymphatic (18.3%). Sclerotherapy was the most frequent treatment (73.4%), followed by medical treatment with sirolimus (18.5%); response to both was excellent/good in > 85% of cases.</p><p><strong>Conclusion: </strong>In this retrospective study of children with VaMs, we found that low-flow malformations were the most common, and sclerotherapy and sirolimus were the most frequently used treatments. The therapeutic response was excellent/good in most cases.</p>","PeriodicalId":9103,"journal":{"name":"Boletín médico del Hospital Infantil de México","volume":"81 4","pages":"232-244"},"PeriodicalIF":0.6,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142139300","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Anemia in children with obesity: is there a higher risk compared to eutrophic children? 肥胖儿童贫血:与富营养儿童相比,肥胖儿童患贫血的风险更高吗?
IF 0.6
Boletín médico del Hospital Infantil de México Pub Date : 2024-01-01 DOI: 10.24875/BMHIM.24000121
Daniel A Jaramillo-Bermeo, Melissa Zavala-Rodríguez, Nadia Gutiérrez-Galicia, Lénica A Chávez-Aguilar, Rubén Peña-Vélez
{"title":"Anemia in children with obesity: is there a higher risk compared to eutrophic children?","authors":"Daniel A Jaramillo-Bermeo, Melissa Zavala-Rodríguez, Nadia Gutiérrez-Galicia, Lénica A Chávez-Aguilar, Rubén Peña-Vélez","doi":"10.24875/BMHIM.24000121","DOIUrl":"https://doi.org/10.24875/BMHIM.24000121","url":null,"abstract":"","PeriodicalId":9103,"journal":{"name":"Boletín médico del Hospital Infantil de México","volume":"81 6","pages":"374-375"},"PeriodicalIF":0.6,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142692475","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Changes in Neonatal Intensive Care Unit statistics during the COVID-19 pandemic. COVID-19 大流行期间新生儿重症监护室统计数据的变化。
IF 0.9
Boletín médico del Hospital Infantil de México Pub Date : 2024-01-01 DOI: 10.24875/BMHIM.M2300003
David Rodríguez-Medina, Luis M Avalos-Huizar, Wendy Bolio-Pontigo, Ma Guadalupe Soto-Castañeda, Julio C Cárdenas-Valdez, Claudia K Medina-Ríos
{"title":"Changes in Neonatal Intensive Care Unit statistics during the COVID-19 pandemic.","authors":"David Rodríguez-Medina, Luis M Avalos-Huizar, Wendy Bolio-Pontigo, Ma Guadalupe Soto-Castañeda, Julio C Cárdenas-Valdez, Claudia K Medina-Ríos","doi":"10.24875/BMHIM.M2300003","DOIUrl":"https://doi.org/10.24875/BMHIM.M2300003","url":null,"abstract":"<p><strong>Background: </strong>With the identification of COVID-19 disease in China, a pandemic began that affected health-care systems. The Neonatal Intensive Care Unit (NICU) of the Hospital de Ginecobstetricia del Centro Médico Nacional de Occidente experienced an increase in patient flow as part of the COVID-19 strategy of the Instituto Mexicano del Seguro Social (IMSS). This study aimed to analyze the impact of the COVID-19 pandemic on neonatal care and mortality indicators in our unit.</p><p><strong>Methods: </strong>We conducted a retrospective study to compare the number of hospital births, pre-term newborns (PTNB), NICU admissions, and deaths. Changes in frequencies between 2019 and 2021 were analyzed using Poisson distribution. Changes in PTNB births, proportion of admissions, and deaths/NICU discharges were analyzed by z-test for two proportions.</p><p><strong>Results: </strong>Between 2019 and 2021, the number of births increased by more than 2-fold. NICU admissions increased from 770 in 2019 to 1045 in 2021 (p < 0.01). The ratio of deaths/discharge from the service was 16.9% in 2019 and 13.1% in 2021 (p = 0.02).</p><p><strong>Conclusions: </strong>Mortality indicators in the NICU decreased from 2019 to 2021, even with the increase in the number of patients admitted during the COVID-19 pandemic.</p>","PeriodicalId":9103,"journal":{"name":"Boletín médico del Hospital Infantil de México","volume":"81 1","pages":"31-35"},"PeriodicalIF":0.9,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140179318","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Risk of alterations in neurodevelopment in infants and preschool children with cancer. 癌症婴儿和学龄前儿童神经发育发生改变的风险。
IF 0.6
Boletín médico del Hospital Infantil de México Pub Date : 2024-01-01 DOI: 10.24875/BMHIM.24000011
Liliana Velasco-Hidalgo, Alejandro González-Garay, Antonio Rizzoli-Córdoba, Roberto Rivera-Luna, Alda García-Guzmán, Ana Gabriela Ortiz-Razo, Evereth Alejandra Olmedo-Jiménez, Rocío Cárdenas-Cardós, Kenya Shamira Carmona-Jaimez, Marta Zapata-Tarrés
{"title":"Risk of alterations in neurodevelopment in infants and preschool children with cancer.","authors":"Liliana Velasco-Hidalgo, Alejandro González-Garay, Antonio Rizzoli-Córdoba, Roberto Rivera-Luna, Alda García-Guzmán, Ana Gabriela Ortiz-Razo, Evereth Alejandra Olmedo-Jiménez, Rocío Cárdenas-Cardós, Kenya Shamira Carmona-Jaimez, Marta Zapata-Tarrés","doi":"10.24875/BMHIM.24000011","DOIUrl":"https://doi.org/10.24875/BMHIM.24000011","url":null,"abstract":"<p><strong>Background: </strong>Some cancer survivors experience difficulties with concentration, attention, and memory; however, there are no studies on neurodevelopment in patients under 5 years of age who are undergoing cancer treatment. Our aim was to evaluate neurodevelopment in cancer patients under 5 years of age using the Early Development Instrument (EDI) test, considering factors such as nutritional status, type of cancer, and treatment effect.</p><p><strong>Methods: </strong>A cross-sectional study was conducted from February 2018 to March 2019. Patients with cancer diagnoses outside the central nervous system in any phase of cancer treatment were included.</p><p><strong>Results: </strong>A total of 45 patients were included. Regarding fine motor skills, 28% of patients with retinoblastoma and 23% of patients with leukemia or lymphoma had a risk of developmental delay compared to 0% of patients with solid tumors (p = 0.025). The final results showed that 19 (42.2%) patients had normal neurodevelopment (gray), 7 (15.5%) had a delay in neurodevelopment (light gray), and 19 (42.2%) had a risk of developmental delay (black). Regarding developmental delay, 52% of patients in the leukemia and lymphoma group, 71% in the retinoblastoma group, and 23% in the solid tumor group presented developmental delay (p = 0.06).</p><p><strong>Conclusions: </strong>The risk of delay and lag in neurodevelopment is common in cancer patients under 5 years of age undergoing treatment. However, more studies are required to evaluate the effect of treatment on this group of patients as it may be affected by various factors.</p>","PeriodicalId":9103,"journal":{"name":"Boletín médico del Hospital Infantil de México","volume":"81 4","pages":"217-224"},"PeriodicalIF":0.6,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142139298","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Prevalence of bacteriuria and bacterial resistance in adolescents from the center of the state of Tlaxcala, Mexico. 墨西哥特拉斯卡拉州中心地区青少年菌尿和细菌耐药性的流行情况。
IF 0.6
Boletín médico del Hospital Infantil de México Pub Date : 2024-01-01 DOI: 10.24875/BMHIM.24000062
Daniela Z Méndez-Polonieski, Pablo Méndez-Hernández, Olivier Barbier, Manolo Ortega-Romero, Juan C Rubio-Gutiérrez, Elodia Rojas-Lima, Juana Narvaez-Morales, Margarita Martínez-Gómez, Estela Cuevas-Romero, Rosalba Cerón-Meza, Mara Medeiros
{"title":"Prevalence of bacteriuria and bacterial resistance in adolescents from the center of the state of Tlaxcala, Mexico.","authors":"Daniela Z Méndez-Polonieski, Pablo Méndez-Hernández, Olivier Barbier, Manolo Ortega-Romero, Juan C Rubio-Gutiérrez, Elodia Rojas-Lima, Juana Narvaez-Morales, Margarita Martínez-Gómez, Estela Cuevas-Romero, Rosalba Cerón-Meza, Mara Medeiros","doi":"10.24875/BMHIM.24000062","DOIUrl":"https://doi.org/10.24875/BMHIM.24000062","url":null,"abstract":"<p><p>Urinary tract infections and bacteriuria are common in the pediatric population, and antibiotic resistance is increasing significantly. Recurrent urinary infections, symptomatic or asymptomatic, are a risk factor for developing chronic kidney disease in adolescents and young adults. This study aimed to assess the prevalence of bacteriuria diagnosed by culture to identify the main causal agents and sensitivity to antibiotics in adolescents from the central region of the state of Tlaxcala. A cross-sectional study was carried out among 905 adolescents from 11 to 18 years old who lived in the central region of the state of Tlaxcala, Mexico. Bacteriuria was evaluated by positive nitrites and leukocyte esterase, and urine culture with antibiogram. Multivariate logistic regression models were executed to evaluate the risk of presenting bacteriuria, with a confidence level of 95%. A total of 31 participants had a positive urine culture, with a bacteriuria prevalence of 3.4%, of which 29 cases were asymptomatic. The most frequent agent was Escherichia coli) in both sexes (28.6% in men and 29.7% in women) and regarding bacterial resistance: E. coli presented greater resistance to ampicillin, trimethoprim/sulfametoxazol and ceftriaxone. The risk factors associated with bacteriuria were female sex, sexual activity, use of contraceptives, and greater consumption of sweetened beverages. Bacteriuria is common in this adolescent population, so its early identification is necessary to treat it, and to prevent its complications.</p>","PeriodicalId":9103,"journal":{"name":"Boletín médico del Hospital Infantil de México","volume":"81 6","pages":"346-355"},"PeriodicalIF":0.6,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142692595","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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