Annals of pediatrics & child health最新文献

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Communicating Prognosis in Sickle Cell Disease: A Qualitative Study of Adolescents with Sickle Cell Disease, Their Parents and Providers. 沟通预后镰状细胞病:青少年镰状细胞病,他们的父母和提供者的定性研究。
Annals of pediatrics & child health Pub Date : 2015-01-01 Epub Date: 2015-01-05
Lydia H Pecker, Michael Roth, Sari Landman, Leslie Cunningham, Ellen Johnson Silver, Deepa Manwani
{"title":"Communicating Prognosis in Sickle Cell Disease: A Qualitative Study of Adolescents with Sickle Cell Disease, Their Parents and Providers.","authors":"Lydia H Pecker, Michael Roth, Sari Landman, Leslie Cunningham, Ellen Johnson Silver, Deepa Manwani","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Adolescents with sickle cell disease (SCD) and their parents are more optimistic about their future than their physicians. This may affect treatment preferences and therapy adherence. Disease specific recommendations for discussing disease course of children with SCD do not exist. To begin to address this gap, we held focus groups for adolescents with SCD 14-21 years old (n=6), parents of adolescents with SCD (n=4) and with pediatric (n=3) and adult (n=2) hematologists. SCD prognosis is complicated due to the uncertain disease course. Fear and worry are associated with discussing the future. Parents disagree with adolescents and hematologists about the best approach to discussing prognosis and oppose prognosticating that includes life expectancy. Guidelines to improve communication between physicians and families are needed.</p>","PeriodicalId":90789,"journal":{"name":"Annals of pediatrics & child health","volume":"3 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2015-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11661846/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142878910","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Acute Bilateral Cataract in Type 1 Diabetes Mellitus. 1型糖尿病并发急性双侧白内障。
Annals of pediatrics & child health Pub Date : 2015-01-01 Epub Date: 2015-10-02 DOI: 10.6084/m9.figshare.13251911.v1
Dimitrios T Papadimitriou, Christina Bothou, Filippos Skarmoutsos, Vassiliki Papaevangelou, Anastasios Papadimitriou
{"title":"Acute Bilateral Cataract in Type 1 Diabetes Mellitus.","authors":"Dimitrios T Papadimitriou,&nbsp;Christina Bothou,&nbsp;Filippos Skarmoutsos,&nbsp;Vassiliki Papaevangelou,&nbsp;Anastasios Papadimitriou","doi":"10.6084/m9.figshare.13251911.v1","DOIUrl":"https://doi.org/10.6084/m9.figshare.13251911.v1","url":null,"abstract":"<p><p>We report a case of a 17-year old boy, who presented acute bilateral cataract and complete vision loss within six days, three months after the diagnosis of Type 1 Diabetes Mellitus (T1DM) under optimal metabolic control (HbA1c 6%). At presentation (HbA1c 10.4%) and after correction of diabetic ketoacidosis (pH 6.917) and the beginning of intensified insulin treatment with insulin glargine once daily and insulin aspart before meals,the patient underwent full ophthalmologic examination,which was completely normal. Only few cases with acute bilateral cataract - all relatively shortly after the diagnosis of T1DM - have been reported. Several hypotheses have been drawn but the exact mechanism of this phenomenon remains unclear. The interesting finding in our case was the clearly elevated insulin autoantibodies (IAA) at the time of cataract formation, negative however at presentation. The relation between the elevation of IAA and cataract formation should be further investigated in diabetic patients.</p>","PeriodicalId":90789,"journal":{"name":"Annals of pediatrics & child health","volume":"3 7","pages":""},"PeriodicalIF":0.0,"publicationDate":"2015-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8373202/pdf/nihms-1636391.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39328536","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
The Role of Vitamin D in Pediatric Asthma. 维生素D在儿童哮喘中的作用。
Annals of pediatrics & child health Pub Date : 2015-01-01
Selene K Bantz, Zhou Zhu, Tao Zheng
{"title":"The Role of Vitamin D in Pediatric Asthma.","authors":"Selene K Bantz,&nbsp;Zhou Zhu,&nbsp;Tao Zheng","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The detrimental effects of vitamin D deficiency in pediatrics have become increasingly apparent and extend beyond skeletal health. Unfortunately, vitamin D deficiency is highly prevalent in atopic pediatric patients, in whom it may disrupt the immune system and induce significant worsening of reactive airways. This review presents evidence that lung development and immune regulatory functions are vitamin D-dependent. We also review clinical studies that explore how vitamin D supplementation may prevent respiratory infections and help improve asthma control, and we elaborate how these effects may vary among populations. We reveal the strong need of screening measures for vitamin D deficiency in high risk pediatric populations, particularly African-Americans, Hispanic-Americans, and children with obesity. Finally, we emphasize that all children, especially those who are asthmatic, should be assessed to ensure adequate intake or supplementation with at least the minimum recommended doses of vitamin D. The simple intervention of vitamin D supplementation may provide significant clinical improvement in atopic disease, especially asthma.</p>","PeriodicalId":90789,"journal":{"name":"Annals of pediatrics & child health","volume":"3 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2015-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4415725/pdf/nihms670899.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"33271262","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Underlying Rationale and Approach to Treat Hypertension in Adolescents by Physicians of Different Specialty. 不同专科医师治疗青少年高血压的基本原理和方法。
Annals of pediatrics & child health Pub Date : 2013-01-01
Esther Y Yoon, Julie S Weber, Brigitte McCool, Albert Rocchini, David Kershaw, Gary Freed, Frank Ascione, Sarah Clark
{"title":"Underlying Rationale and Approach to Treat Hypertension in Adolescents by Physicians of Different Specialty.","authors":"Esther Y Yoon,&nbsp;Julie S Weber,&nbsp;Brigitte McCool,&nbsp;Albert Rocchini,&nbsp;David Kershaw,&nbsp;Gary Freed,&nbsp;Frank Ascione,&nbsp;Sarah Clark","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Objective: </strong>To describe the underlying clinical decision-making rationale among general pediatricians, family physicians, pediatric cardiologists and pediatric nephrologists in their approach to an adolescent with hypertension.</p><p><strong>Methods: </strong>We conducted semi-structured phone interviews with a convenience sample of physicians from the above-mentioned 4 specialties. Each participant was asked to \"think aloud\" regarding their approach to a hypothetical patient - 12 year old boy with persistent hypertension for 6 months. Standardized open-ended questions about potential factors that could affect physicians' diagnosis and treatment strategies (e.g., patient age) were used. Interviews were audio-recorded; transcribed verbatim; transcripts were independently coded by 2 investigators; emergent themes identified and inter-coder agreement achieved. Thematic analysis was performed based on grounded theory.</p><p><strong>Results: </strong>Nineteen participants included 5 general pediatricians, 5 pediatric cardiologists, 5 pediatric nephrologists and 4 family physicians. Five themes emerged: 1) Accuracy of blood pressure measurement and hypertension diagnosis, 2) Shift in the epidemiology of pediatric hypertension from secondary to primary hypertension, 3) Patient characteristics considered in the decision to initiate workup, 4) Obesity-centered choice of diagnostic tests and lifestyle modifications, and 5) Variable threshold for initiating antihypertensive pharmacotherapy vs. referral to hypertension specialists.</p><p><strong>Conclusions: </strong>There is variation across primary care and specialty physicians who provide care for children and adolescents with hypertension. Key areas of variability include the willingness to initiate antihypertensive medications, the use of diagnostic tests (e.g., ambulatory blood pressure monitoring), and the perceived need for specialty referral. Further study is needed to assess whether different treatment paradigms result in differential patient outcomes.</p>","PeriodicalId":90789,"journal":{"name":"Annals of pediatrics & child health","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2013-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4300960/pdf/nihms573887.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"33003096","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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