Ata Murat Kaynar, Nicole Zharichenko, Ajay D Wasan, Jacques E Chelly
{"title":"Telemedicine-Based Digital Cognitive Behavioral Intervention for Perioperative Anxiety and Depression for Total Knee Arthroplasty.","authors":"Ata Murat Kaynar, Nicole Zharichenko, Ajay D Wasan, Jacques E Chelly","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Introduction: </strong>Preoperative anxiety and depression have been shown to increase postoperative pain and opioid consumption by up to 50% in patients undergoing primary unilateral Total Knee Arthroplasty (TKA). We hypothesized that the use of a telemedicine-based digital Cognitive Behavioral Intervention program (RxWell<sup>®</sup>) started one month prior to surgery would control anxiety and depression prior to surgery.</p><p><strong>Materials and methods: </strong>This was a randomized, controlled trial that enrolled patients undergoing primary unilateral TKA. At least a month prior to surgery, patients who gave consent to participate were asked to complete PROMIS<sup>®</sup> (Patient-Reported Outcomes Measurement Information System) emotional anxiety short form 8a and PROMIS<sup>®</sup> emotional depression short form-8a questionnaires. Patients with T-scores of ≥ 57 were randomized to either a no intervention (control group) or a RxWell<sup>®</sup> program (treatment group) for a month prior to surgery. The primary outcome of this proof-of-concept study was the ability of the RxWell<sup>®</sup> to normalize patients' PROMIS anxiety T scores.</p><p><strong>Results: </strong>T scores for anxiety and depression among patients randomized to the RxWell<sup>®</sup> group significantly decreased from 64.3 ± 3.0 at the time of randomization to 58.5 ± 2.6 prior to surgery (n=5, p=0.006), whereas no changes in T scores were recorded in the control group (59.4 ± 4.2 at the time of randomization <i>vs</i>. 57.7 ± 6.2; n=6, p=0.559).</p><p><strong>Conclusion: </strong>These preliminary data suggest that the use of a RxWell<sup>®</sup> program represents an effective approach to control anxiety and depression prior to surgery. In contrast, it seems that in the absence of treatment, anxiety level remains similar over a month prior to surgery.</p>","PeriodicalId":90614,"journal":{"name":"Journal of pain & relief","volume":"12 9","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10601399/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"54232746","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jacques E Chelly, Brian Klatt, Michael O'Malley, Yram Groff, Jeremy Kearns, Sharad Khetarpal, Senthil Sadhasivam
{"title":"The Role of Inhalation Aromatherapy, Lavender and Peppermint in the Management of Perioperative Pain and Opioid Consumption Following Primary Unilateral Total Hip Arthroplasty: A Prospective, Randomized and Placebo-Controlled Study.","authors":"Jacques E Chelly, Brian Klatt, Michael O'Malley, Yram Groff, Jeremy Kearns, Sharad Khetarpal, Senthil Sadhasivam","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Introduction: </strong>Aromatherapy is claimed to be effective for the treatment of psychosocial disorders, but objective evidence of its effectiveness is still lacking. Psychosocial disorders have been demonstrated to increase postoperative pain and opioid consumption by up to 50%. This study was designed to assess the effectiveness of Aromatherapy in controlling postoperative pain and opioid in anxious patients.</p><p><strong>Methods: </strong>This prospective, randomized, placebo-controlled study was conducted on anxious patients who underwent primary unilateral total hip arthroplasty. After obtaining signed informed consent, each patient was asked to complete a PROMIS (Patient-Reported Outcomes Measurement Information System) anxiety survey. Patients whose T score were >57.2 were randomized to either an active treatment (Lavender Peppermint Elequil<sup>®</sup> aromatab<sup>®</sup>) or a placebo Elequil<sup>®</sup>-aromatab<sup>®</sup> treatment. Demographics, pain, opioid consumption, PONV, and psychosocial surveys were collected on Postoperative Day POD1, POD2, POD7 and POD30. At the time of discharge and on POD30, each patient was asked to complete a satisfaction questionnaire, and they were asked to complete an SF12 survey on POD30. Difference between means was assessed using absolute standardized mean differences.</p><p><strong>Results: </strong>Sixty patients were included in the intend-to-treat analysis. Use of lavender and peppermint was associated with a decrease of 26% in pain (POD7; 0.46), 33% in opioid consumption (POD2; 0.42), and 48% in acetaminophen consumption (POD7; 0.54) and a 78% decrease in PONV (POD2; 0.44). Psychosocial scores decreased following surgery (p=0.001). Overall satisfaction ratings at discharge were similar, as were functional recovery scores.</p><p><strong>Discussion: </strong>Our data provides evidence that in patients with preoperative anxiety, lavender and peppermint aromas decreases postoperative pain and opioid requirement compared to placebo. Additional research is required to conform our data.</p><p><strong>Conclusion: </strong>This randomized placebo control study provides evidence of the usefulness of inhalation of lavender and peppermint aromas in patients undergoing primary unilateral total hip arthroplasty.</p>","PeriodicalId":90614,"journal":{"name":"Journal of pain & relief","volume":"12 Suppl 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10854480/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139725313","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Shiv Goel, Charles Luke, Matthew Holtzman, Benjamin Davies, Michael O'Malley, Dani Lavage, Carley Siedlecki, Jacques E Chelly
{"title":"Safety and Efficacy of Zynrelef<sup>®</sup> in Combination with a Single Unilateral or Bilateral Nerve Block Performed Prior to Surgery.","authors":"Shiv Goel, Charles Luke, Matthew Holtzman, Benjamin Davies, Michael O'Malley, Dani Lavage, Carley Siedlecki, Jacques E Chelly","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Purpose: </strong>The FDA recently approved Zynrelef<sup>®</sup> (A viscous solution of extended release of bupivacaine and meloxicam) to be applied at closure and providing postoperative analgesia for 72 hrs. Although the FDA didn't restrict the use of nerve blocks in combination with this formulation, the safety and efficacy of such a combination has yet to be documented. This quality improvement study investigated this combination within the FDA-approved indications.</p><p><strong>Methods: </strong>Selected surgeons at two hospitals were chosen to use Zynrelef<sup>®</sup>. According to the standard of care, surgeons were also allowed to request single nerve blocks before surgery. The type of nerve blocks (unilateral or bilateral) performed included quadratus lumborum and paravertebral blocks for abdominal surgery, and adductor canal block for total knee replacement. Each block was performed with 20 mL of 0.375% bupivacaine (n=129) or 0.5% of ropivacaine (n=30). Pain scores, opioid consumption, and prescription refill requests at discharge were recorded. Patients discharged on the same day of surgery were separated into two groups-those who received single nerve blocks plus an Zynrelef<sup>®</sup> (group 1) <i>vs.</i> those receiving Zynrelef<sup>®</sup> only (group 2) and was analyzed using an un-paired t-test.</p><p><strong>Results: </strong>A total of 184 patients received Zynrelef<sup>®</sup>, including 25 patients who didn't receive blocks, 44 who received unilateral blocks and 114 who received bilateral blocks. No symptoms suggestive of Local Anesthetic Toxicity (LAST) were observed. The use of the combination was associated with a 50% reduction in the number of patients filling their opioid prescription.</p><p><strong>Conclusion: </strong>This study provides evidence that the combination of a single unilateral or bilateral nerve block with Zynrelef<sup>®</sup> is safe.</p>","PeriodicalId":90614,"journal":{"name":"Journal of pain & relief","volume":"12 Suppl 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11064821/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140871713","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
N. Živković, N. Repac, A. Janicijevic, I. Nikolic, B. Djurović
{"title":"Lumbar Radiculopathy Caused by Degenerative Osteoarthritis and Epidural Lipoma","authors":"N. Živković, N. Repac, A. Janicijevic, I. Nikolic, B. Djurović","doi":"10.4172/2167-0846.1000337","DOIUrl":"https://doi.org/10.4172/2167-0846.1000337","url":null,"abstract":"","PeriodicalId":90614,"journal":{"name":"Journal of pain & relief","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.4172/2167-0846.1000337","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70805979","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A. B., L. R., Urda Martinez-Aedo A, Noriega-Bastos M, Dominguez-Esteban I, Marco Martinez F
{"title":"High-frequency Spinal Cord Stimulation as a Palliative Treatment for Patients with Low Back and Lower Extremity Radiated Chronic Pain","authors":"A. B., L. R., Urda Martinez-Aedo A, Noriega-Bastos M, Dominguez-Esteban I, Marco Martinez F","doi":"10.4172/2167-0846.1000341","DOIUrl":"https://doi.org/10.4172/2167-0846.1000341","url":null,"abstract":"","PeriodicalId":90614,"journal":{"name":"Journal of pain & relief","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.4172/2167-0846.1000341","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70805864","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A Multicenter Study on Neuropathic Pain in China: Characteristics and the Efficacy of Pregabalin","authors":"H. L., Yan Zw, Shen Qy, Wang Yd, Peng Y","doi":"10.4172/2167-0846.1000340","DOIUrl":"https://doi.org/10.4172/2167-0846.1000340","url":null,"abstract":"","PeriodicalId":90614,"journal":{"name":"Journal of pain & relief","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.4172/2167-0846.1000340","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70806215","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Chronic Pain Management and Its Relationship to Physiological Variables","authors":"E. Hapidou, K. Culig","doi":"10.4172/2167-0846.1000339","DOIUrl":"https://doi.org/10.4172/2167-0846.1000339","url":null,"abstract":"","PeriodicalId":90614,"journal":{"name":"Journal of pain & relief","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.4172/2167-0846.1000339","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70806277","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
S. Khademi, A. Farbood, Elham Sabokseir, Mandana Ghani
{"title":"Effect of Pre-operative Oral Gabapentin on Postoperative Pain in Opioiddependent Patients Undergoing Orthopedic Surgeries of the Lower Extremity: A Randomized Double-blind Placebo-controlled Trial","authors":"S. Khademi, A. Farbood, Elham Sabokseir, Mandana Ghani","doi":"10.4172/2167-0846.1000336","DOIUrl":"https://doi.org/10.4172/2167-0846.1000336","url":null,"abstract":"","PeriodicalId":90614,"journal":{"name":"Journal of pain & relief","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.4172/2167-0846.1000336","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70805930","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Hip Pain Revealing Metastatic Prostate Cancer","authors":"T. Youssoufi, F. Haddani, A. Guich, H. Hassikou","doi":"10.4172/2167-0846.1000338","DOIUrl":"https://doi.org/10.4172/2167-0846.1000338","url":null,"abstract":"Background: Prostate cancer is the most common malignant tumor and the second most common cause of cancer associated mortality in males. Bone metastasis is frequent, usually multiple and osteoplastic. Presentation of a pure osteolytic and solitary metastasis from a prostate carcinoma is extremely rare. Methodology: We report a case of prostate cancer in a 54-year-old man who presented with progressive severe right hip pain and stiffness with no urinary symptom. An MRI of the pelvis revealed a metastasis to the right hip. A prostate biopsy revealed prostate adenocarcinoma. Results: In the literature, there are few cases of a solitary osteolytic bone metastasis from carcinoma of the prostate, and especially in the pelvis. only one such case seems to be reporting.","PeriodicalId":90614,"journal":{"name":"Journal of pain & relief","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.4172/2167-0846.1000338","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70806076","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Alexa R Meins, Ardith Z Doorenbos, Linda Eaton, Debra Gordon, Brian Theodore, David Tauben
{"title":"TelePain: A Community of Practice for Pain Management.","authors":"Alexa R Meins, Ardith Z Doorenbos, Linda Eaton, Debra Gordon, Brian Theodore, David Tauben","doi":"10.4172/2167-0846.1000177","DOIUrl":"https://doi.org/10.4172/2167-0846.1000177","url":null,"abstract":"<p><strong>Introduction: </strong>Comprehensive pain management services are primarily located in urban areas, limiting specialist consultation opportunities for community healthcare providers. A community of practice (CoP) for pain management could create opportunities for consultation by establishing professional relationships between community healthcare providers and pain management specialists. A CoP is a group of people with a common concern, set of problems, or a passion for something they do. Members of a CoP for pain management increase their knowledge of evidence-based pain management strategies in a way that is meaningful and relevant. In this article, we provide evidence that TelePain, an interdisciplinary, case-based pain management teleconference consultation program through the University of Washington, qualifies as a CoP and present preliminary evidence of TelePain's effectiveness as a CoP for pain management.</p><p><strong>Methods: </strong>Specific behaviors and conversations gathered through participant observation during TelePain sessions were analyzed based on the 14 indicators Wegner developed to evaluate the presence of a CoP. To demonstrate preliminary effectiveness of TelePain as a CoP for pain management, descriptive statistics were used to summarize TelePain evaluation forms.</p><p><strong>Results: </strong>TelePain is an example of a successful CoP for pain management as demonstrated by the presence of Wegner's 14 indicators. Additionally, evaluation forms showed that TelePain enhanced community healthcare providers' knowledge of pain management strategies and that continued participation in TelePain lead to community healthcare providers' increased confidence in their ability to provide pain management.</p><p><strong>Conclusion: </strong>TelePain, a CoP for pain management, facilitates multidisciplinary collaboration and allows members to develop interdisciplinary care plans for complex pain patients through case study discussions. Evidence-based pain management strategies gained through CoP membership could be disseminated to other healthcare providers in members' clinics, which has the potential of improving the care of chronic pain patients.</p>","PeriodicalId":90614,"journal":{"name":"Journal of pain & relief","volume":"4 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2015-03-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.4172/2167-0846.1000177","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"33295817","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}