{"title":"Ending nuclear weapons, before they end us.","authors":"Chris Zielinski","doi":"10.1136/bmjebm-2025-113922","DOIUrl":"10.1136/bmjebm-2025-113922","url":null,"abstract":"","PeriodicalId":9059,"journal":{"name":"BMJ Evidence-Based Medicine","volume":" ","pages":"282-284"},"PeriodicalIF":7.6,"publicationDate":"2025-07-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12320584/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144075873","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Fiona Campbell, Anthea Sutton, Danielle Pollock, Chantelle Garritty, Andrea C Tricco, Lena Schmidt, Hanan Khalil
{"title":"Rapid reviews methods series: guidance on rapid scoping, mapping and evidence and gap map ('Big Picture Reviews').","authors":"Fiona Campbell, Anthea Sutton, Danielle Pollock, Chantelle Garritty, Andrea C Tricco, Lena Schmidt, Hanan Khalil","doi":"10.1136/bmjebm-2023-112389","DOIUrl":"10.1136/bmjebm-2023-112389","url":null,"abstract":"","PeriodicalId":9059,"journal":{"name":"BMJ Evidence-Based Medicine","volume":" ","pages":"268-277"},"PeriodicalIF":7.6,"publicationDate":"2025-07-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12320599/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143188195","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Julian Treadwell, Laura C Armitage, Kiana K Collins, Laura Heath, Olu Onyimadu, Mandy Payne, Azizia Wahedi, Kamal R Mahtani
{"title":"Co-production and implementation of an evidence collation strategy for a novel point-of-care information resource: gpevidence.org.","authors":"Julian Treadwell, Laura C Armitage, Kiana K Collins, Laura Heath, Olu Onyimadu, Mandy Payne, Azizia Wahedi, Kamal R Mahtani","doi":"10.1136/bmjebm-2025-113715","DOIUrl":"https://doi.org/10.1136/bmjebm-2025-113715","url":null,"abstract":"","PeriodicalId":9059,"journal":{"name":"BMJ Evidence-Based Medicine","volume":" ","pages":""},"PeriodicalIF":9.0,"publicationDate":"2025-07-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144667088","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Zhi-Jun Bu, Feng-Shuang Liu, Md Shahjalal, Yi-Ke Song, Meng-Chi Li, Rong-Er Zhuo, Qing-Hong Zhong, Ya-Wen Du, Chen-Ge Lu, Zi-Han Yang, Han-Yu Yang, Pu Zhong, Jian-Ping Liu, Zhao-Lan Liu
{"title":"Effects of various exercise interventions in insomnia patients: a systematic review and network meta-analysis.","authors":"Zhi-Jun Bu, Feng-Shuang Liu, Md Shahjalal, Yi-Ke Song, Meng-Chi Li, Rong-Er Zhuo, Qing-Hong Zhong, Ya-Wen Du, Chen-Ge Lu, Zi-Han Yang, Han-Yu Yang, Pu Zhong, Jian-Ping Liu, Zhao-Lan Liu","doi":"10.1136/bmjebm-2024-113512","DOIUrl":"https://doi.org/10.1136/bmjebm-2024-113512","url":null,"abstract":"<p><strong>Objectives: </strong>To compare the effectiveness of different exercise interventions in improving sleep quality and alleviating insomnia severity among patients with insomnia.</p><p><strong>Design: </strong>Our study design was a systematic review and network meta-analysis.</p><p><strong>Eligibility criteria: </strong>Our study eligibility criteria was restricted to include randomised controlled trials (RCTs) involving adults with insomnia that evaluated exercise-based interventions.</p><p><strong>Data sources: </strong>PubMed, Cochrane Library, Embase, Web of Science, SPORTDiscus, and PsycINFO databases were systematically searched from inception to 1 April 2025.</p><p><strong>Risk of bias and certainty assessment: </strong>Risk of bias was assessed using the Cochrane Risk of Bias 2 Tool. The certainty of the evidence was evaluated using the Confidence in Network Meta-Analysis (CINeMA) platform.</p><p><strong>Synthesis of results: </strong>A frequentist network meta-analysis was performed to assess the effectiveness of interventions, with outcomes presented as mean differences (MDs) and 95% confidence intervals (95% CIs). Sleep outcomes were measured using validated tools, including the Pittsburgh Sleep Quality Index (PSQI), Insomnia Severity Index (ISI), sleep diaries, and combined objective sleep measures such as polysomnography or actigraphy.</p><p><strong>Results: </strong>The review included 1348 participants from 22 RCTs, examining 13 distinct interventions, of which seven were exercise-based: yoga, Tai Chi, walking or jogging, aerobic plus strength exercise, strength training alone, aerobic exercise combined with therapy, and mixed aerobic exercises. Among the included trials, four (18%) were rated as low risk of bias, 15 (68%) had some concerns, and three (14%) were considered to have a high risk. Compared with active controls (eg, usual care, lifestyle modifications), yoga likely results in a large increase in total sleep time (MD 110.88 minutes (min), 95% CI 58.66 to 163.09; moderate-certainty evidence) and may improve sleep efficiency (MD 15.59%, 95% CI 5.76 to 25.42; low-certainty evidence), reduce wake after sleep onset (MD -55.91 min, 95% CI -98.14 to -13.68; low-certainty evidence), and shorten sleep onset latency (MD -29.27 min, 95% CI -50.09 to -8.45; low-certainty evidence), all based on sleep diary data. Walking or jogging may result in a large reduction in ISI scores (MD -9.57 points, 95% CI -12.12 to -7.02; low-certainty evidence). Tai Chi may reduce PSQI scores (MD -4.57 points, 95% CI -7.50 to -1.63; low-certainty evidence), increase total sleep time (MD 52.07 min, 95% CI 25.53 to 78.61; low-certainty evidence), reduce wake after sleep onset (MD -36.11 min, 95% CI -62.81 to -9.42; low-certainty evidence), and shorten sleep onset latency (MD -24.76 min, 95% CI -41.07 to -8.46; low-certainty evidence), also based on sleep diary data. Additionally, Tai Chi may increase total sleep time as measured by combined obje","PeriodicalId":9059,"journal":{"name":"BMJ Evidence-Based Medicine","volume":" ","pages":""},"PeriodicalIF":9.0,"publicationDate":"2025-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144641756","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Danielle Marie Muscat, Tessa Copp, Brooke Nickel, Kirsten McCaffery
{"title":"Examining the layered health literacy demands in low-value care contexts.","authors":"Danielle Marie Muscat, Tessa Copp, Brooke Nickel, Kirsten McCaffery","doi":"10.1136/bmjebm-2024-113443","DOIUrl":"https://doi.org/10.1136/bmjebm-2024-113443","url":null,"abstract":"","PeriodicalId":9059,"journal":{"name":"BMJ Evidence-Based Medicine","volume":" ","pages":""},"PeriodicalIF":9.0,"publicationDate":"2025-07-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144616164","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Crystal N Steltenpohl, Brinna Mawhinney, Veli-Matti Karhulahti, Annayah M B Prosser
{"title":"Open science for qualitative research.","authors":"Crystal N Steltenpohl, Brinna Mawhinney, Veli-Matti Karhulahti, Annayah M B Prosser","doi":"10.1136/bmjebm-2024-113532","DOIUrl":"https://doi.org/10.1136/bmjebm-2024-113532","url":null,"abstract":"<p><p>Open scholarship practices-often also referred to as open research or open science-are increasingly seen as relevant to the research lifecycle. What open scholarship looks like in practice will inevitably vary by field, methodology, epistemology, access to resources, and other considerations. In this article, we outline a few important considerations for researchers who use qualitative research methods in deciding which open scholarship practices are most applicable for their own work and suggest a few practices that may be of interest, namely data sharing, preregistration, negative case analysis, audit trails and member checking. Engagement or disengagement of any given practice should be guided by demands of research epistemology, context, community, topicn and methodology. Finally, we suggest a few places for researchers to start if they wish to learn more about open scholarship more broadly and engage with critical conversations around these practices.</p>","PeriodicalId":9059,"journal":{"name":"BMJ Evidence-Based Medicine","volume":" ","pages":""},"PeriodicalIF":9.0,"publicationDate":"2025-07-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144616165","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Randi Foraker, Jon D Morrow, Julie A Johnson, Adam B Wilcox, Alan J Forster, Philip R O Payne
{"title":"Understanding synthetic data: artificial datasets for real-world evidence.","authors":"Randi Foraker, Jon D Morrow, Julie A Johnson, Adam B Wilcox, Alan J Forster, Philip R O Payne","doi":"10.1136/bmjebm-2024-113617","DOIUrl":"https://doi.org/10.1136/bmjebm-2024-113617","url":null,"abstract":"","PeriodicalId":9059,"journal":{"name":"BMJ Evidence-Based Medicine","volume":" ","pages":""},"PeriodicalIF":9.0,"publicationDate":"2025-07-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144552073","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Yuting Duan, Zhirui Xu, Yongqi Zhang, Shujuan Liu, Juexuan Chen, Yaolong Chen, Nenggui Xu, Chunzhi Tang, Peijing Rong, Liming Lu, Yu Wang, Ye-Seul Lee, Tae-Hun Kim, David S Riley, Lin Shi, Myeong Soo Lee, Lin Yu
{"title":"CARE extension guideline for acupuncture case reports.","authors":"Yuting Duan, Zhirui Xu, Yongqi Zhang, Shujuan Liu, Juexuan Chen, Yaolong Chen, Nenggui Xu, Chunzhi Tang, Peijing Rong, Liming Lu, Yu Wang, Ye-Seul Lee, Tae-Hun Kim, David S Riley, Lin Shi, Myeong Soo Lee, Lin Yu","doi":"10.1136/bmjebm-2025-113641","DOIUrl":"10.1136/bmjebm-2025-113641","url":null,"abstract":"<p><p>Existing reporting checklists lack the specificity and comprehensiveness required to effectively guide the documentation of acupuncture case reports. Therefore, we developed a reporting guideline tailored specifically for acupuncture case reports, building upon the CAse REport (CARE) statement. A multidisciplinary group of international experts including clinicians, researchers and methodologists was convened to draft the initial checklist in accordance with the methodology recommended by the Enhancing the QUAlity and Transparency Of health Research (EQUATOR) network. Through an extensive literature review and a series of expert interviews, the final CARE for acupuncture checklist comprised of 30 items. 38 experts from diverse disciplines participated in three rounds of modified Delphi surveys to refine and clarify these items. CARE for acupuncture is a comprehensive reporting guideline focused on acupuncture case reports developed with rigorous methodology. We hope that CARE for acupuncture will further guide authors, editors, peer reviewers and readers to enhance the transparency, completeness and accuracy of reporting of case reports in acupuncture.</p>","PeriodicalId":9059,"journal":{"name":"BMJ Evidence-Based Medicine","volume":" ","pages":""},"PeriodicalIF":9.0,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144494545","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Wayne Gao, Min-Kuang Tsai, Thu Win Kyaw, Yea-Hung Chen
{"title":"Outcomes of the first national oral cancer screening programme in Taiwan, 2004-2022: a population-based study.","authors":"Wayne Gao, Min-Kuang Tsai, Thu Win Kyaw, Yea-Hung Chen","doi":"10.1136/bmjebm-2024-113340","DOIUrl":"https://doi.org/10.1136/bmjebm-2024-113340","url":null,"abstract":"<p><strong>Objective: </strong>This study evaluates whether Taiwan's national oral cancer screening programme, implemented in 1999, has led to a reduction in late-stage oral cancer and mortality.</p><p><strong>Design: </strong>An observational population-based ecological cohort study (2004-2022) using data from the Taiwan Cancer Registry, a nationwide cancer registry.</p><p><strong>Setting: </strong>Taiwan, an island nation with a population of 23.5 million.</p><p><strong>Participants: </strong>The entire male population in the nation diagnosed with oral cancer between 2004 and 2022.</p><p><strong>Main outcome measures: </strong>Change in stage-specific, age-standardised incidence and mortality of oral cancer and their annual percentage change (APC). We hypothesised that an effective screening programme would lead to an increase in early-stage cancer diagnoses while reducing late-stage cancer incidence and mortality.</p><p><strong>Results: </strong>A total of 92 342 males were diagnosed with oral cancer in Taiwan between 2004 and 2022. Following the introduction of the national oral cancer screening programme, the incidence of early-stage (stages 0-1) oral cancer increased 2.4-fold from 6.6 to 14.5 per 100 000 males between 2004 and 2013 (APC: 11.3% (95% CI 9.4% to 13.5%), p<0.001). However, early-stage incidence subsequently declined to 11.8 per 100 000 males by 2022 (APC: -3.2% (95% CI -5.2% to -1.6%), p<0.001), corresponding to a period of decreased screening uptake between 2015 and 2022. The late-stage (stages 2-4) oral cancer increased from 24.5 to 28.3 per 100 000 males between 2004 and 2009 (APC: 3.3% (95% CI 1.8% to 6.6%), p<0.001) and then remained relatively stable between 2009 and 2022 (APC: 0.1% (95% CI -0.5% to 0.5%), p=0.65). Oral cancer mortality increased from 14.4 to 16.6 per 100 000 males over the entire examined period between 2004 and 2022 (APC: 0.76% (95% CI 0.5% to 1.1%), p<0.001), showing no observed decline despite two decades of screening efforts and a continued decrease in prevalence of betel quid use.</p><p><strong>Conclusions: </strong>Although oral cancer screening detected more early-stage cancer, no reduction in population late-stage incidence or mortality was observed. Therefore, reducing betel quid and cigarette consumption should be the primary focus for oral cancer control. The public health response to oral cancer should borrow from lessons learnt in tobacco control.</p>","PeriodicalId":9059,"journal":{"name":"BMJ Evidence-Based Medicine","volume":" ","pages":""},"PeriodicalIF":9.0,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144538412","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Accurate is not enough: select formats for communicating probabilities to achieve specific outcomes.","authors":"Brian J Zikmund-Fisher, Jessica S Ancker","doi":"10.1136/bmjebm-2025-113738","DOIUrl":"10.1136/bmjebm-2025-113738","url":null,"abstract":"","PeriodicalId":9059,"journal":{"name":"BMJ Evidence-Based Medicine","volume":" ","pages":""},"PeriodicalIF":7.6,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12320222/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144538411","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}