International journal of medical and pharmaceutical case reports最新文献

{"title":"Eagle Syndrome: A Case Report and Review of the Literature","authors":"O. Hamdaoui, G. El-Mahfoudi, H. Tabakh, A. Siwane, N. Touil, O. Kacimi, N. Chikhaoui","doi":"10.9734/ijmpcr/2022/v15i430167","DOIUrl":"https://doi.org/10.9734/ijmpcr/2022/v15i430167","url":null,"abstract":"Eagle's syndrome, stylo-carotid syndrome, elongated styloid process syndrome or American syndrome is a rare and controversial entity. It is characterized by a long styloid process causing irritation of the surrounding structures. We report a case of Eagle's syndrome of incidental discovery in a 53-year-old patient, with no particular history, who presented with intense left retro-mandibular pain evolving for two years. A computer tomography angiography (CTA) of the supra-aortic trunks was ordered and showed two bilateral bony processes extending from the styloid process towards the lesser horn of the hyoid bone, indicating ossification of the stylohyoid ligament, which led to the diagnosis of Eagle syndrome.","PeriodicalId":90548,"journal":{"name":"International journal of medical and pharmaceutical case reports","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-08-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46955859","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Polycythemia Rubra Vera: A Case Report","authors":".. Ambika, Ujjawal Rawat, P. Mittal, Ajay Kumar","doi":"10.9734/ijmpcr/2022/v15i430166","DOIUrl":"https://doi.org/10.9734/ijmpcr/2022/v15i430166","url":null,"abstract":"Polycythemia vera, also denoted as polycythemia rubra vera is a Philadelphia chromosome (Ph)-negative myeloproliferative neoplasm which usually affects 2.5-10 people per 100000 people. Max cases are present in people age 60 years of age, out of which 10% patients are under the age of 40. The below presented case is an original case of 37-year-old female who presented to us with this condition with a history of insomnia, Fronto- parietal headache, a systemic itch that deteriorates after a hot water bath along with loss of concentration from last 6 weeks and early satiety, discomfort in the upper right abdomen and drastic weight loss from previous one month. The blood test depicted markedly increased hemoglobin (23.8g/dl). A bone marrow biopsy was done and it was confirmed that the patient is suffering from PRV. The patient was treated with phlebotomy, aspirin, and Ruxolitinib.","PeriodicalId":90548,"journal":{"name":"International journal of medical and pharmaceutical case reports","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-08-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41981902","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Primary Systemic Amyloidosis of Tongue: Pitfall and Challenges in the Diagnosis","authors":"Agarwal Anshoo, V. V. Ermilov, N. A. Dorofeev, Singh Yanina, T. Afaf","doi":"10.9734/ijmpcr/2022/v15i430165","DOIUrl":"https://doi.org/10.9734/ijmpcr/2022/v15i430165","url":null,"abstract":"Amyloidosis is caused by the deposition of insoluble fibrillary protein in tissues and organs resulting in severe organ dysfunction. The clinical presentation for the diagnosis of amyloidosis is nonspecific, making it one of the most underdiagnosed conditions. Treatment is now available and is effective in improving patients’ survival and quality of life. We present a case of generalized amyloidosis in a 71-year-old patient admitted with a diagnosis of benign neoplasm of the root of the tongue. Subsequently, she underwent surgical treatment followed by purulent-septic complications developed leading to death. Microscopic examination of the biopsy tissue revealed deposits of amyloid and the patient was diagnosed to have primary generalized amyloidosis. These facts confirm the essential need to differentiate tumors from amyloidosis. Hence, this paper aims to provide physicians with knowledge about the clinical presentation that raises the suspicion of amyloidosis, bearing in mind the importance of early diagnosis.","PeriodicalId":90548,"journal":{"name":"International journal of medical and pharmaceutical case reports","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-08-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43024648","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Plexiform Neurofibroma of Arm: A Case Report","authors":"O. Hamdaoui, O. Kardi, H. Tabakh, A. Siwane, N. Touil, O. Kacimi, N. Chikhaoui","doi":"10.9734/ijmpcr/2022/v15i430164","DOIUrl":"https://doi.org/10.9734/ijmpcr/2022/v15i430164","url":null,"abstract":"Plexiform Neurofibroma (PNF) is a rare benign nerve tumor. It is usually considered pathognomonic of neurofibromatosis type 1 (NF1 or Von Recklinghausen disease). MRI is the examination of choice in the exploration of this pathology. It provides decisive arguments for the positive diagnosis, the evaluation of the prognosis and the follow-up of the lesions. Histological confirmation is sometimes necessary, especially in cases other than NF1. We report the observation of a 22-year-old woman who consulted for a mass of the left arm.","PeriodicalId":90548,"journal":{"name":"International journal of medical and pharmaceutical case reports","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-08-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45151955","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pharmacognostic, Acute Toxicity Profile and Comparative Leaf Characteristics of Desmodium velutinum, Mallotus oppositifolius and Synedrella nodiflora","authors":"Ifeanyi Peter Onyeka, F. Onyegbule, Chioma Ifeoma Ibe, H.M.N. Ifebi, C. O. Ezugwu","doi":"10.9734/ijmpcr/2022/v15i430163","DOIUrl":"https://doi.org/10.9734/ijmpcr/2022/v15i430163","url":null,"abstract":"Plant leaf parameters such as stomatal index, stomata type, leaf microscopic features, and leaf powder microscopy are important taxonomic parameters used to properly identify species and to differentiate one species from another and these is a vital keys in the pharmacognostic study of the medicinal plants because leaf parameters play a vital role in distinguishing crude drugs even when they are fragmented or powdered. Also, extractive index, retention factor, ash value, and phytochemical parameters are vital in the standardization of crude drugs for the establishment of pharmacopeia and monograms. Therefore, the study seeks to validate the use of the phytochemistry and molecular systematics among Asteraceae, Euphorbiaceae, and Fabaceae to support their circumscription and therefore evaluated the pharmacognostic profile of Desmodium velutinum, Synedrella nodiflora and Mallotus oppositifolius folklorically used in South East Nigeria using standard laboratory protocols. The result of the leaf microscopy showed that Desmodium velutinum, Synedrella nodiflora, and Mallotus oppositifolius all had irregular shaped leaf epidermis, and stomata was present only in the abaxial surface respectively. The result showed both D. velutinum and S. nodiflora powder showed the presence of lignin, starch, cystoliths, tannin, and Oil body while calcium oxalate was absent whereas, Mallotus oppositifolius showed the presence of lignin, starch, tannin, and Oil body while calcium oxalate, and cystoliths were absent. Also the result of the TLC showed that M. oppositifolius had 3 visible spots with retention factors (RF) of  0.363, 0.425, and 0.5 in that order  respectively, D. velutinum had 4 visible spot with retention factor (RF) of  0.425, 0.5, 0.550 and 0.66 in that order  respectively  while S. nodiflora had 6 visible spot with retention factor (RF) of  0.255, 0.363, 0.438, 0.538, 0.600 and 0.688 in that order  respectively. The result also showed that methanol exhaustible extracted the phytochemicals in the crude dried plant. The acute toxicity studies showed that Desmodium velutinum, Synedrella nodiflora and Mallotus oppositifolius individually had LD50 greater than 5000mg/kg. This study validates the claim that leaf parameters such as stomatal index, stomata type, leaf powder microscopy are important parameters used for the identification of crude drugs.","PeriodicalId":90548,"journal":{"name":"International journal of medical and pharmaceutical case reports","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-07-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43257472","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Melatonin Involvement in Syncope Associated with Sleep Disturbance: A Case Report","authors":"O. M. Onwuka, Adaobi Linda Okerulu, N. Nwosu","doi":"10.9734/ijmpcr/2022/v15i430162","DOIUrl":"https://doi.org/10.9734/ijmpcr/2022/v15i430162","url":null,"abstract":"Background: Syncope or fainting associated with sleep disturbance is mostly diagnosed as vasovagal syncope and has also been linked to orthostatic or postural hypotension. The physiological basis of syncope associated with sleep disturbance is not fully elucidated. In this report a rare case of melatonin involvement in syncope associated with sleep disturbance was presented. \u0000Case Presentation: A case of a 21-year-old female with syncope associated with sleep disturbance was examined with 1 hour post syncope melatonin concentration of 33pg/ml (daytime evaluation) which is on the increase when compared to its female referenced average value (10pg/ml daytime evaluation). Some vital physiological variables associated with syncope like heart rate, blood pressure, hemoglobin concentration and packed cell volume were normal compared to referenced value (Table 1 and Table 2). \u0000Conclusion: Considering the evaluations presented, it is suggested that melatonin could be involved in the sleep disturbance induced syncope and this report has created de novo insight that will aid elucidation, diagnosis and intervention of syncope induced by sleep disturbance or obstruction.","PeriodicalId":90548,"journal":{"name":"International journal of medical and pharmaceutical case reports","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-07-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46826311","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Modified Clinical Practice of Sariva Kshara Sutra with Partial Fistulectomy in the Management of Bhagandara (Fistula-In-Ano)","authors":"N. Shah, O. Dave","doi":"10.9734/ijmpcr/2022/v15i430161","DOIUrl":"https://doi.org/10.9734/ijmpcr/2022/v15i430161","url":null,"abstract":"Bhagandara is Ashta Mahagaroga (8 major disease) by Sushruta because of highest recurrence. Anorectal disorders are at peak, because to sedentary lifestyle and many other factors. 2 words Bhaga and Darana is bifurcation bhagandara, it is a common disease occurring in Anorectal region around the anus which may extends up to Genitalia. Pidika creation causes Bhagandara to develop, which is countered by opening up in the Guda Pradesh region with suffering and discharge. Kshara Sutra therapy is the one-of-a-kind, specific Parasurgical procedure that is employed in Fistula in Ano. Bhagandara is treated using a variety of modern scientific modalities, but to far no single modality has proven to be comprehensive for Fistula. The goal of the current study was to evaluate the modified way to treat fistula-in-ano with Sariva Kshara Sutra with partial fistulectomy. Case was taken from OPD/IPD of SHAH PILES FISTULA HOSPITAL, AHMEDABAD. \u0000CASE 1: - Age 31 yrs. Male Patient came to our hospital with complain of pain, swelling, discharge in scrotal to anterior anal canal (scrotal extension) treated with Sariva Kshara Sutra with partial fistulectomy considering its a best procedure in the treatment of Bhagandara preserving the Sphincter it treats the track.","PeriodicalId":90548,"journal":{"name":"International journal of medical and pharmaceutical case reports","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-06-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46989604","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Stafne Bone Cyst in the Right Mandibular Angle Region: A Case Report with Literature Review","authors":"Arun Panwar, V. Keluskar, Rigdha Verenkar, L. S, S. M, J. T, Revati Keluskar","doi":"10.9734/ijmpcr/2022/v15i330160","DOIUrl":"https://doi.org/10.9734/ijmpcr/2022/v15i330160","url":null,"abstract":"Stafne bone cysts (SBC) are rare, small, well-demarcated, and radiolucent lesions that usually occur below the mandibular canal near the mandibular angle. Despite several theories, the etiopathogenesis of SBC remains unknown. As SBCs usually show no clinical signs, radiographic evaluation is the first stage of the diagnostic process. When the lesions are atypical, as in our instance, correct differential diagnosis is critical. This case study presents an unusual Type I SBC in a 66 year old man and reviews relevant literature.","PeriodicalId":90548,"journal":{"name":"International journal of medical and pharmaceutical case reports","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-06-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48390584","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"An Unusual Presentation of Inflammatory Fibrous Hyperplasia: A Case Report with a Brief Literature Review","authors":"Arun Panwar, V. Keluskar, Rigdha Verenkar, L. Kumar S., S. M","doi":"10.9734/ijmpcr/2022/v15i330159","DOIUrl":"https://doi.org/10.9734/ijmpcr/2022/v15i330159","url":null,"abstract":"A mucosal lesion that arises due to long standing chronic irritation is called Epulis fissuratum. It is a benign reactive hyperplastic lesion that commonly develops in the mucosa close to the overextending flanges of the ill-fitting dentures. This paper presents a case of atypical presentation of epulis fissaratum in a 74-year-old woman with history of ill-fitting denture for the past four months. Total excision of such lesions is recommended because they cause problems such as pain and discomfort during mastication and speech.","PeriodicalId":90548,"journal":{"name":"International journal of medical and pharmaceutical case reports","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-05-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48783092","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Heart Failure Associated with Rheumatoid Arthritis","authors":"M. Akrim, S. Jourani, A. Chachi, M. E. Hattaoui","doi":"10.9734/ijmpcr/2022/v15i330157","DOIUrl":"https://doi.org/10.9734/ijmpcr/2022/v15i330157","url":null,"abstract":"Rheumatoid arthritis (RA) is a chronic inflammatory disease of the joints. Extra-articular features are very common. We report a case of RA first diagnosed after an episode of congestive heart failure (CHF) and the evolution of left ventricular function after conventional treatment of CHF and immunosuppressive drugs. The patient, a 52-year-old man, with history of epilepsy and a stroke 6 years before, presented to the emergency department with increasing dyspnea. He had polyarthralgia 2 months before. The lower extremities had mild pitting edema. The musculoskeletal examination revealed synovial thickening of the metacarpophalangeal and proximal interphalangeal \u0000joints, but there was no joint tenderness. The patient’s alanine aminotransferase, troponin levels and CRP were slightly elevated. His renal function was preserved. The electrocardiogram (EKG) was normal. An echocardiogram performed in showed a global hypokinetic dilated cardiomyopathy with an ejection fraction of 15–20%, with apical thrombus. The patient was diagnosed with exacerbation \u0000of congestive heart failure (CHF) and was treated with intravenous diuretics. This led to symptomatic improvement.  He got a conventional heart failure treatment with vit K antagonists. Coronarography was normal. Viral serologies were negative. The martial, phosphocalcic and thyroid markers were normal. However, the immunologic tests showed positive rheumatoid factor and anti-CCP. The diagnosis of dilated cardiomyopathy due to rheumatoid arthritis was retained. The patient was treated by corticosteroids and immunosuppressive agents. Patient was seen during routine follow-up after 6 months. Interestingly, echocardiographic findings were totally normal with left ventricular ejection fraction >50% and normal LV size.","PeriodicalId":90548,"journal":{"name":"International journal of medical and pharmaceutical case reports","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-04-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41700354","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}