Polycythemia Rubra Vera: A Case Report

.. Ambika, Ujjawal Rawat, P. Mittal, Ajay Kumar
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Abstract

Polycythemia vera, also denoted as polycythemia rubra vera is a Philadelphia chromosome (Ph)-negative myeloproliferative neoplasm which usually affects 2.5-10 people per 100000 people. Max cases are present in people age 60 years of age, out of which 10% patients are under the age of 40. The below presented case is an original case of 37-year-old female who presented to us with this condition with a history of insomnia, Fronto- parietal headache, a systemic itch that deteriorates after a hot water bath along with loss of concentration from last 6 weeks and early satiety, discomfort in the upper right abdomen and drastic weight loss from previous one month. The blood test depicted markedly increased hemoglobin (23.8g/dl). A bone marrow biopsy was done and it was confirmed that the patient is suffering from PRV. The patient was treated with phlebotomy, aspirin, and Ruxolitinib.
维拉红细胞增多症一例报告
真性红细胞增多症,也称为真性红细胞增生症,是一种费城染色体(Ph)阴性的骨髓增生性肿瘤,通常每100000人中有2.5-10人感染。最大病例出现在60岁的人群中,其中10%的患者年龄在40岁以下。以下病例是一例37岁女性的原始病例,她向我们介绍了这种情况,有失眠、额顶叶头痛、热水澡后全身瘙痒恶化、过去6周注意力不集中、早期饱腹、右上腹部不适和前一个月体重急剧下降的病史。血液检查显示血红蛋白明显增加(23.8g/dl)。进行了骨髓活检,证实患者患有PRV。患者接受了静脉切开术、阿司匹林和鲁索利替尼治疗。
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