International journal of medical and pharmaceutical case reports最新文献

{"title":"Valproate and Pediatric Stevens-Johnson Syndrome: A Critical Alert","authors":"Jafrin Sadiq Abdul Razack, Syeda Juveria Hussaini, Saud Khaled Aldoseri, Hisham Abubacker Musthafa, Antony Calvin Ossanam, Ibtisam Akram, Sahil Asgar Ali, Mohamed Ahmed Ebrahim Ahmed Abdulla, Vivek Karan","doi":"10.9734/ijmpcr/2024/v17i3389","DOIUrl":"https://doi.org/10.9734/ijmpcr/2024/v17i3389","url":null,"abstract":"Stevens-Johnson Syndrome is a severe condition that affects the skin and mucous membranes, often caused by medications or infections. This case study details the experience of a three-year-old boy who developed SJS after beginning valproate treatment for seizure management following a traumatic brain injury. Initially, he showed symptoms of fever, facial redness, and a runny nose, which progressed to a severe rash and blisters. A dermatologist confirmed the diagnosis of SJS linked to valproate. Swift diagnosis, discontinuation of the offending drug, and supportive care are essential in managing SJS and preventing serious complications. Early intervention and comprehensive care from a variety of medical professionals are crucial for improving patient outcomes.","PeriodicalId":90548,"journal":{"name":"International journal of medical and pharmaceutical case reports","volume":"119 28","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141819991","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Intra- and Extraconical Cavernous Hemangiomas in Children: The Difficulty of Therapeutic Management","authors":"Hassina Salma, Hazil Z, B. B, B. C., Krichene Ma, H. I, R. L, A. Y, S. L, Abdallah El","doi":"10.9734/ijmpcr/2024/v17i3388","DOIUrl":"https://doi.org/10.9734/ijmpcr/2024/v17i3388","url":null,"abstract":"This article describes the case of a 10-year-old girl with a rare presentation of extra- and intra-conical cavernous hemangioma in children. After undergoing complete surgical excision, the exophthalmos completely regressed, and no recurrence was observed during the two-year follow-up period. The treatment options discussed included intratumoral corticosteroid injection, oral corticosteroid therapy, and surgical excision.","PeriodicalId":90548,"journal":{"name":"International journal of medical and pharmaceutical case reports","volume":"67 5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141701786","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Brain Meningioma Mimicking Eclampsia: A Report of Two Cases","authors":"Alkhalil Hm, Benaguida H, Djibadje H, E. M, Raja A, Hafiani Y, E. M, Salmi M","doi":"10.9734/ijmpcr/2024/v17i3385","DOIUrl":"https://doi.org/10.9734/ijmpcr/2024/v17i3385","url":null,"abstract":"Seizures occurring during pregnancy and postpartum may lead to the suspicion of eclampsia. However, it is essential to conduct paraclinical examinations (brain CT scan and brain MRI) to rule out cerebral expansive processes. In this main article, we report two cases of patients admitted for eclampsia, in whom a diagnosis of meningioma was made. Based on the observations, we discuss the different entities of this pathology with data from the literature.","PeriodicalId":90548,"journal":{"name":"International journal of medical and pharmaceutical case reports","volume":"45 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141353171","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Unveiling Dieulafoy’s Lesion: A Case Report on Upper Gastrointestinal Bleeding Caused by Dieulafoy’s Lesion","authors":"Praveena R Prasad, A. U, Shaiju. S. Dharan, D. L., Dhanya Dharman","doi":"10.9734/ijmpcr/2024/v17i3384","DOIUrl":"https://doi.org/10.9734/ijmpcr/2024/v17i3384","url":null,"abstract":"Dieulafoy’s lesion is a rare entity, mostly found in stomach (53%), followed by the duodenum or jejunum (33%) and lastly colon or rectum (13%). Although relatively infrequent, Dieulafoy’s lesion indicates an important etiology of acute gastrointestinal bleeding because of its predisposition to cause massive, life-threatening and recurrent bleeding. We report a female patient with clinical presentation of hematemesis and melena for 2 day’s duration.","PeriodicalId":90548,"journal":{"name":"International journal of medical and pharmaceutical case reports","volume":"28 6","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141353544","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Psychiatric Presentation of a Severe Vitamin B12 Deficiency Associated with Biermer’s Disease: A Case Report","authors":"El Adraoui Yassine, Slimani Sarah, Mouloudi Najoua, Hamid Mohamed, Benmoh Youssouf, Bourazza Ahmed","doi":"10.9734/ijmpcr/2024/v17i3382","DOIUrl":"https://doi.org/10.9734/ijmpcr/2024/v17i3382","url":null,"abstract":"This case report highlights a 57-year-old female patient presenting with psychiatric symptoms such as depressive mood, social withdrawal, and apathy followed by gait disturbances and tremor, which led to the diagnosis of severe Vitamin B12 deficiency-induced encephalopathy. Despite initially displaying only psychiatric symptoms, MRI revealed cerebral leukoencephalopathy. Metabolic and auto-immune evaluation confirmed profound Vitamin B12 deficiency secondary to Biermer's disease. Treatment with Vitamin B12 replacement therapy resulted in a favorable outcome. This case underscores the importance of considering Vitamin B12 deficiency in patients with neuropsychiatric symptoms, as timely diagnosis and treatment can prevent long-term complications.","PeriodicalId":90548,"journal":{"name":"International journal of medical and pharmaceutical case reports","volume":"13 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141273969","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cerebral Thrombophlebitis of the Post Partum: About Two Cases","authors":"Alkhalil HM, Allal Z, Afif A, Elharit M, Raja A, Hafiani Y, El Youssoufi M, Salmi M","doi":"10.9734/ijmpcr/2024/v17i3383","DOIUrl":"https://doi.org/10.9734/ijmpcr/2024/v17i3383","url":null,"abstract":"Cerebral thrombophlebitis is an uncommon localisation that should be considered in the presence of headache, fever, focal deficit in the context of pregnancy or post partum. It is positive diagnosis is made by imaging but the etiological diagnosis remains the main issue. In this main article, we report two cases of patients treated for cerebral thrombophlebitis. From the observations made, we will discuss the different entities of this pathology with the data of the literature.","PeriodicalId":90548,"journal":{"name":"International journal of medical and pharmaceutical case reports","volume":"17 21","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141272823","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Methotrexate Induced Oral Mucositis and Bone Marrow Suppression in Psoriatic Patient","authors":".. Aadithya, Raghuveer S Prabhu, Rahmathullah Sn","doi":"10.9734/ijmpcr/2024/v17i2381","DOIUrl":"https://doi.org/10.9734/ijmpcr/2024/v17i2381","url":null,"abstract":"Methotrexate is an antimetabolite which binds to the dihydrofolate reductase enzyme and used in the treatment of malignant disorders and autoimmune diseases. Myelosuppression is a serious complication of methotrexate toxicity. The following case describes a case of 67 year old male patient diagnosed with psoriasis and wrongly taken methotrexate 7.5 mg daily for 3 days and twice daily for 4 days. He presented with oral mucositis and his lab reports showed myelosuppression. Our case emphasizes the significance of effective patient counselling to ensure the understanding of prescription and to prevent drug toxicity. The key learning points of our case report include the importance of adhering to prescribed medication regimens, awareness of MTX toxicity, early initiation of folinic acid as an antidote, vigilant monitoring of toxicity, and effective patient education on proper medication use. Adherence to established MTX therapy guidelines in dermatological conditions is crucial to minimize the risk of patient.","PeriodicalId":90548,"journal":{"name":"International journal of medical and pharmaceutical case reports","volume":"2 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141099252","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Continuous Epidural Catheter for Postoperative Analgesia in Children: A Case Report","authors":"I. Bejja, K. Bendamia, A. El Koraichi","doi":"10.9734/ijmpcr/2024/v17i2380","DOIUrl":"https://doi.org/10.9734/ijmpcr/2024/v17i2380","url":null,"abstract":"The management of postoperative pain in children and infants has now become a significant concern. Continuous epidural anesthesia is a proven method for controlling acute pain after surgery. \u0000We present the case of thoracic epidural analgesia used for the repair of an extensive burn involving the back and trunk, assisted by a skin graft, in a 6-year-old girl. Department of Pediatric Intensive Care Unit, Children's Hospital of Rabat. \u0000In pediatric surgery, postoperative pain awareness is crucial for medical and paramedical teams. Continuous epidural anesthesia, utilizing suitable equipment, is feasible for young children. Its advantages during long procedures are manifold: it eliminates the need for central analgesics, ensuring stable cardiovascular function and a calm awakening post-surgery. Moreover, it provides high-quality analgesia in the postoperative phase, decreasing morbidity and easing care for children. With safe analgesics and advances in locoregional anesthesia, managing postoperative pain in pediatrics has markedly improved.","PeriodicalId":90548,"journal":{"name":"International journal of medical and pharmaceutical case reports","volume":"12 7","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141106946","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pericardial Effusion as an Early Indicator of Breast Cancer Recurrence: A Case Report","authors":"B. Abdalani, O. Moufid, Meriem Amri, S.M. Obeidat, A. Assklou, M. Benouna, A. Drighil, R. Habbal","doi":"10.9734/ijmpcr/2024/v17i2379","DOIUrl":"https://doi.org/10.9734/ijmpcr/2024/v17i2379","url":null,"abstract":"Background: Pericardial effusion, though uncommon, poses a significant threat to patient well-being, particularly when associated with underlying malignancies such as breast cancer recurrence. Timely recognition and intervention are crucial for improved prognosis and patient outcomes. \u0000Case Presentation: We present the case of a 51-year-old woman with a history of treated breast cancer who presented with rapidly worsening dyspnea. Clinical examination and diagnostic tests revealed a large pericardial effusion secondary to breast cancer recurrence, highlighting the diagnostic and therapeutic challenges associated with this condition. \u0000Discussion: Breast cancer recurrence involving the pericardium signifies advanced disease and presents significant management complexities. Evaluation typically involves transthoracic echocardiography and pericardiocentesis, with treatment strategies focusing on systemic chemotherapy and symptom management. \u0000Conclusion: Pericardial effusion can serve as an early indicator of breast cancer recurrence and requires a multidisciplinary approach for optimal management. Early recognition and intervention are paramount in improving patient outcomes and quality of life.","PeriodicalId":90548,"journal":{"name":"International journal of medical and pharmaceutical case reports","volume":"59 7","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141116971","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Insights into Nephrotic Syndrome in Pediarics: Case Series Analysis","authors":"V. Sireesha, Asiya Sultana, P. R. Sri, Ayesha Mateen, M. Shiva, T. R. Rao","doi":"10.9734/ijmpcr/2024/v17i2378","DOIUrl":"https://doi.org/10.9734/ijmpcr/2024/v17i2378","url":null,"abstract":"Nephrotic syndrome (NS) is one of the most common childhood kidney diseases. NS can affect children of any age from infancy to adolescence and predominantly occurs in the age group of 1–6 years. It is an illness caused by idiopathic diseases like minimal change nephrotic syndrome (MCNS) and focal segmental glomerulosclerosis (FSGS), membrane proliferative Glomerulonephritis, membranous Glomerulonephritis and is characterized by increased permeability across the glomerular filtration barrier. NS is classified as primary, secondary, and congenital. It consists of four clinical features like severe proteinuria, edema, hyperlipidaemia, hypoalbuminemia. The main cause of nephrotic syndrome are diseases associated with drugs and rarely genetic disorders. The pathogenesis of the disease affects various biological functions linked to loss of proteins negatively, which results in systemic complications which may be disease and drug-associated complications. Using drugs to treat NS leads to several complications which include improper growth, metabolism, behavior change inpatient. Itis a chronic relapsing disease for most of the steroid response drugs for treatment of nephrotic syndrome. Glucocorticoids, immunosuppressants and biological agents are used for the treatment of the diseases. In this case series, we presented a case series of nephrotic syndrome in pediatrics. Total 4 patients were taken into considerations. The patients came with a chief complaints of swelling of face, foamy urine, abdominal pain, dark coloured urine with decreased urine output, joint pains. The laboratory investigations for all the 4 patients showed that there were decrease in albumin levels (hypoalbuminemia), decrease in serum creatinine levels and protein in urine, although kidney biopsy couldn’t be perform but the diagnosis was made based on clinical and laboratory findings. The patients were mainly treated with prednisolone, pantoprazole, enalapril, nifedipine, amoxiclav, and even albumin transfusion were done. NS was successfully managed and fortunately the patients recovered.","PeriodicalId":90548,"journal":{"name":"International journal of medical and pharmaceutical case reports","volume":"67 17","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140964671","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}