International journal of medical and pharmaceutical case reports最新文献_第2页

Lupus Journey: The Challenge of Obstructıve Hydrocephalus 狼疮之旅：梗阻性脑积水的挑战

International journal of medical and pharmaceutical case reports Pub Date : 2024-05-08 DOI: 10.9734/ijmpcr/2024/v17i2377

Dilara Bulut Gökten, Murat Gökten, R. Mercan

引用次数: 0

Cardiac Tamponade: An Unusual First Case Presentation of Systemic Lupus Erythematosus 心脏填塞：系统性红斑狼疮的罕见首发病例

International journal of medical and pharmaceutical case reports Pub Date : 2024-04-19 DOI: 10.9734/ijmpcr/2024/v17i2374

D. Sarah, Jama Dounia, Charif Hanae, Mounaouir Karim, Bouziane Maha, Haboub Meryem, B. Ghali, Drighil Abdenasser, Habbal Rachida

{"title":"Cardiac Tamponade: An Unusual First Case Presentation of Systemic Lupus Erythematosus","authors":"D. Sarah, Jama Dounia, Charif Hanae, Mounaouir Karim, Bouziane Maha, Haboub Meryem, B. Ghali, Drighil Abdenasser, Habbal Rachida","doi":"10.9734/ijmpcr/2024/v17i2374","DOIUrl":"https://doi.org/10.9734/ijmpcr/2024/v17i2374","url":null,"abstract":"This case is reported for the rarity of cardiac tamponade as a first manifestation of systemic lupus erythematosus (SLE). Systemic lupus erythematosus (SLE) is a multisystem autoimmune disease with worldwide prevalence, affecting almost every organ in the body. A 27-year-old woman presented to our hospital after two months of progressive shortness of breath, generalized edematous syndrome and diffuse, non-migratory arthralgias; the patient's shortness of breath was exacerbated on exertion and associated with a vague sensation of chest tightness. Transthoracic echocardiography revealed a large circumferential pericardial effusion with an echo-free space of 34 mm in apical view and 36 mm in subcoastal view with an oscillating heart and diastolic collapse of the right ventricle and atrium. This case is reported for the rarity of cardiac tamponade as a first manifestation of SLE. Because pericarditis is more common in SLE patients, the low frequency of tamponade may be partially explained by the extensive use of non-steroidal anti-inflammatory medications (NSAIDs) and steroids, which effectively reduce pericardial inflammation. We emphasize the importance of including SLE in the differential diagnosis of patients presenting with cardiovascular symptoms, as cardiac tamponade and pleural effusion are uncommon early presentations of SLE. Early detection and diagnosis are essential for prompt intervention and better patient outcomes.","PeriodicalId":90548,"journal":{"name":"International journal of medical and pharmaceutical case reports","volume":" 84","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140683543","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Fulminant Hepatitis Secondary to Anti-tuberculosis Drug-induced Hepatotoxicity Complication, Its Prevention Strategies and Management: A Case Report 继发于抗结核药物肝毒性并发症的暴发性肝炎及其预防策略和处理：病例报告

International journal of medical and pharmaceutical case reports Pub Date : 2024-04-11 DOI: 10.9734/ijmpcr/2024/v17i2373

S. Fjouji, Abdelhafid Houba, C. Chouikh, Imad Rahali, H. Bakkali, N. Doghmi, Hicham Balkhi

{"title":"Fulminant Hepatitis Secondary to Anti-tuberculosis Drug-induced Hepatotoxicity Complication, Its Prevention Strategies and Management: A Case Report","authors":"S. Fjouji, Abdelhafid Houba, C. Chouikh, Imad Rahali, H. Bakkali, N. Doghmi, Hicham Balkhi","doi":"10.9734/ijmpcr/2024/v17i2373","DOIUrl":"https://doi.org/10.9734/ijmpcr/2024/v17i2373","url":null,"abstract":"Aim: Tuberculosis remains a public health problem around the world. Hepatotoxicity is a serious side effect of anti-tuberculosis treatment. Fulminant hepatitis is a rare form but considered very serious outside of liver transplantation. It can occur several weeks or months after the start of treatment. \u0000Presentation of Case: We report the case of a 34-year-old single male patient treated for pleural tuberculosis in whom fulminant hepatitis appeared after four months of treatment with Isoniazid and Rifampicin. Despite a treatment in intensive care unit He had a fatal outcome because of lack of liver transplantation. \u0000Discussion: Hepatotoxicity varies from biological hepatitis to fulminant hepatitis. Application of personalized strategy of genetic analysis and pharmacological drug monitoring to optimize treatment is the most safe to avoid antituberculosis drug induced hepatotoxicity but not available in all healthcare centers of developing countries. There was any change of anti-tuberculosis protocol because of the risk of bacterial resistance. The protocol includes association between several medicines potentially toxics for a long duration. For some moderate forms of tuberculosis (nodals, pleural), it’s necessary to ask if duration of antiviotherapy can be reduced. \u0000Conclusion: Prevention of hepatotoxicity starts with identifying risk factors, regular clinical and biological assessment and informing patients of symptom that can indicate toxicity to react early.","PeriodicalId":90548,"journal":{"name":"International journal of medical and pharmaceutical case reports","volume":"1 7","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140713196","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Nightmares Associated to Nevirapine during Chemoradiotherapy for Carcinoma Tongue 舌癌化疗期间服用奈韦拉平会做噩梦

International journal of medical and pharmaceutical case reports Pub Date : 2024-04-11 DOI: 10.9734/ijmpcr/2024/v17i2372

Bhooshan Zade, Vrushab Rao

引用次数: 0

Tuberculous Pericarditis: A Case Report in South-east Nigeria 结核性心包炎：尼日利亚东南部的病例报告

International journal of medical and pharmaceutical case reports Pub Date : 2024-04-06 DOI: 10.9734/ijmpcr/2024/v17i2371

Okpara Titus Chukwubuzo, O. P. Chibuike, Chime Peter Ekpunobi, Eze Uchenna Gerald, A. Uchechukwu, Anike Raphael Ugwu, E. J. Chukwudi, Ozougwu Augustine Obumneme, Ngwoke Anthonia Onyinye, Ogu Rita Ifeoma-Ossy, Enukora Nkiru, Magaji Nyamaai Cephas

{"title":"Tuberculous Pericarditis: A Case Report in South-east Nigeria","authors":"Okpara Titus Chukwubuzo, O. P. Chibuike, Chime Peter Ekpunobi, Eze Uchenna Gerald, A. Uchechukwu, Anike Raphael Ugwu, E. J. Chukwudi, Ozougwu Augustine Obumneme, Ngwoke Anthonia Onyinye, Ogu Rita Ifeoma-Ossy, Enukora Nkiru, Magaji Nyamaai Cephas","doi":"10.9734/ijmpcr/2024/v17i2371","DOIUrl":"https://doi.org/10.9734/ijmpcr/2024/v17i2371","url":null,"abstract":"Tuberculosis is a chronic infection and a common cause of chronic pericardial effusion. Approximately 1-2% of patients with pulmonary tuberculosis (PTB) develop tuberculous pericarditis (TBP) and it is less common in the developed world than in developing countries where active tuberculosis is endemic. In these countries with high endemicity, TBP is the most common form of pericarditis and is often associated with HIV. The clinical picture is usually that of a chronic systemic illness in a patient with pericardial effusion. The index case is that of a 24 year old male, who had presented to our medical outpatient clinic with a history of cough and chest pain of 9 and 2 days duration respectively. Diagnosis was made following echocardiography, electrocardiography (ECG), Chest X-ray (CXR) and culture findings which showed features in keeping with tuberculous pericarditis. His clinical condition improved significantly following pericardiocentesis and TB treatment was subsequently instituted. He was discharged for outpatient follow-up 5 days after pericardiocentesis. TBP can be difficult to diagnose and often goes undetected especially in resource poor countries. Accurate and early diagnosis is important as it is a dangerous disease if left untreated.","PeriodicalId":90548,"journal":{"name":"International journal of medical and pharmaceutical case reports","volume":"31 9","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140734287","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Antiphospholipid Syndrome and Impaired Wound Healing After CABG 抗磷脂综合征与 CABG 术后伤口愈合受损

International journal of medical and pharmaceutical case reports Pub Date : 2024-04-05 DOI: 10.9734/ijmpcr/2024/v17i2370

Jafrin Sadiq Abdul Razack, Saud Khaled Aldoseri, Sahil Asgar Ali, Syeda Juveria Hussaini, Firas Raouf Alani

引用次数: 0

Case Report on Brown Tumor: An Unusual Expression of Renal Osteodystrophy and Secondary Hyperparathyroidism 布朗瘤病例报告：肾骨质营养不良和继发性甲状旁腺功能亢进症的异常表现

International journal of medical and pharmaceutical case reports Pub Date : 2024-04-02 DOI: 10.9734/ijmpcr/2024/v17i2368

Abhishek S Krishna, Harikrishnan V Nair, Sandeep K F, Shaiju S Dharan, Dhanya Dharman

{"title":"Case Report on Brown Tumor: An Unusual Expression of Renal Osteodystrophy and Secondary Hyperparathyroidism","authors":"Abhishek S Krishna, Harikrishnan V Nair, Sandeep K F, Shaiju S Dharan, Dhanya Dharman","doi":"10.9734/ijmpcr/2024/v17i2368","DOIUrl":"https://doi.org/10.9734/ijmpcr/2024/v17i2368","url":null,"abstract":"The new term of ‘Chronic Kidney Disease- Mineral and Bone Disorders’ has been introduced to encompass a wide-ranging syndrome, capturing various abnormalities in bone and mineral metabolism seen in patients with chronic kidney disease. Multifactorial disorders affecting mineral metabolism and bone structure emerge early in the progression of Chronic Kidney Disease. Brown tumors, an uncommon type of bone lesion are distinctive manifestations of high-turnover bone disease. In this case, a patient with chronic kidney disease (dialysis dependent) with IgA nephropathy that presented with multiple osseous lesions of bilateral ribs, sternum, scapula, clavicle, mandible and vertebral bodies. The case highlights the significance of considering brown tumors in the differential diagnosis and management of patients with both an osseous mass and chronic kidney disease. Failing to establish an accurate diagnosis may result in unnecessary additional diagnostic procedures and extensive surgery, ultimately increasing patient morbidity. Through this case report, the importance of preventing, early diagnosing, and treating secondary hyperparathyroidism to reduce the prevalence of high-turnover bone disease and associated complications such as brown tumors is emphasized.","PeriodicalId":90548,"journal":{"name":"International journal of medical and pharmaceutical case reports","volume":"96 8","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140754748","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Through Indian Eyes: A Case Series on Steroid-induced Secondary Cataract 透过印度人的眼睛：类固醇引起的继发性白内障病例系列

International journal of medical and pharmaceutical case reports Pub Date : 2024-03-26 DOI: 10.9734/ijmpcr/2024/v17i2367

B. S. Girish, C. S. Meghana, Joel M Johns, R. Srinivasan

{"title":"Through Indian Eyes: A Case Series on Steroid-induced Secondary Cataract","authors":"B. S. Girish, C. S. Meghana, Joel M Johns, R. Srinivasan","doi":"10.9734/ijmpcr/2024/v17i2367","DOIUrl":"https://doi.org/10.9734/ijmpcr/2024/v17i2367","url":null,"abstract":"Lichen planus, a chronic autoimmune dermatological disorder, often necessitates the use of topical corticosteroids for symptom management. However, this case series highlights the emergence of topical steroid-induced secondary cataracts in two patients, emphasizing a previously underrecognized complication. Both patients, females aged 36 and 43, presented with gradual vision loss in their left eyes, attributed to prolonged corticosteroid use for lichen planus and skin allergies, respectively. Ophthalmological examinations confirmed the diagnosis, leading to cataract surgeries. The pathogenesis involves complex cellular and molecular mechanisms, emphasizing the need for vigilant monitoring during corticosteroid therapy. Moreover, the lack of stringent reporting systems for adverse drug reactions in India underscores the necessity for comprehensive monitoring to mitigate economic and quality of life burdens. The study emphasizes the importance of judicious corticosteroid use, tapering regimens, and patient education to minimize complications while effectively managing dermatological conditions. This underscores the critical need for heightened awareness, surveillance, and patient-centred approaches to mitigate the risk of corticosteroid-induced secondary cataracts, ensuring optimal therapeutic outcomes and long-term ocular health.","PeriodicalId":90548,"journal":{"name":"International journal of medical and pharmaceutical case reports","volume":"119 35","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140378688","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Challenges of Cutaneous Care in Hyperthyroidism: A Case Report 甲亢患者皮肤护理的挑战：病例报告

International journal of medical and pharmaceutical case reports Pub Date : 2024-03-23 DOI: 10.9734/ijmpcr/2024/v17i2366

Amaewhule, Mn, Amadi, Es, Korubo, IF., Gomba, VE, Wokekoro, PJ, Wariboko, C., Figilo, IM Douglas, BI, Robinson-Elechi, E., Harry, Md, Onyenma, PO

{"title":"Challenges of Cutaneous Care in Hyperthyroidism: A Case Report","authors":"Amaewhule, Mn, Amadi, Es, Korubo, IF., Gomba, VE, Wokekoro, PJ, Wariboko, C., Figilo, IM Douglas, BI, Robinson-Elechi, E., Harry, Md, Onyenma, PO","doi":"10.9734/ijmpcr/2024/v17i2366","DOIUrl":"https://doi.org/10.9734/ijmpcr/2024/v17i2366","url":null,"abstract":"Cutaneous manifestations of thyroid disease are one of the first notable signs of thyroid hormone dysregulation. Skin changes in hyperthyroidism vary from individual to individual. In dark skinned Africans it may be challenging to detect these dermatoses and care for the patients with these dermatoses if they arise. Making the actual cutaneous diagnosis in hyperthyroidism may be impaired by co-morbidities, drug-drug interactions, hypersensitive reactions, unusual presentation of common diseases, immunosuppression that may result to opportunistic infections and similar presentations of dermatoses. There may be dermatoses that may co-exist with other dermatoses within the same site. The peculiarity of our case report is that we present three females with hyperthyroidism that cut across different age groups with different cutaneous lesions. This case report aims to present the challenges of making accurate skin diagnosis and challenges that arise in actually caring for them. Counselling the patient on the appropriate care and prognosis of these skin lesions would help in improvement of quality of life and unwanted expectations","PeriodicalId":90548,"journal":{"name":"International journal of medical and pharmaceutical case reports","volume":" 12","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140210593","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Solitary Breast Human Cysticercosis Simulating Benign Tumor in a Young Female 一名年轻女性的乳腺人类单发囊尾蚴病模拟良性肿瘤

International journal of medical and pharmaceutical case reports Pub Date : 2024-03-11 DOI: 10.9734/ijmpcr/2024/v17i1365

Prakriti Shukla

引用次数: 0