Valproate and Pediatric Stevens-Johnson Syndrome: A Critical Alert

Abstract

Stevens-Johnson Syndrome is a severe condition that affects the skin and mucous membranes, often caused by medications or infections. This case study details the experience of a three-year-old boy who developed SJS after beginning valproate treatment for seizure management following a traumatic brain injury. Initially, he showed symptoms of fever, facial redness, and a runny nose, which progressed to a severe rash and blisters. A dermatologist confirmed the diagnosis of SJS linked to valproate. Swift diagnosis, discontinuation of the offending drug, and supportive care are essential in managing SJS and preventing serious complications. Early intervention and comprehensive care from a variety of medical professionals are crucial for improving patient outcomes.