Case reports in clinical pathology最新文献

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Lipoleiomyoma: An incidental finding in a case of uterine serous adenocarcinoma 脂质肌瘤:子宫浆液性腺癌的偶然发现
Case reports in clinical pathology Pub Date : 2020-06-26 DOI: 10.5430/crcp.v7n1p15
John Weichsler, S. Starr
{"title":"Lipoleiomyoma: An incidental finding in a case of uterine serous adenocarcinoma","authors":"John Weichsler, S. Starr","doi":"10.5430/crcp.v7n1p15","DOIUrl":"https://doi.org/10.5430/crcp.v7n1p15","url":null,"abstract":"We present a rare case of a lipoleiomyoma which was discovered incidentally in a hysterectomy specimen of a 74-year old female patient who underwent surgery for a biopsy proven serous adenocarcinoma of the uterus. Lipoleiomyomas represent uncommon, usually benign soft-tissue tumors, generally found in obese menopausal as well as postmenopausal women aged 50 to 70 years. The reported incidence varies from 0.03% to 0.2%. The relationship between lipoleiomyomas and gynecologic malignancies has only been reported in a few cases. We report this case of lipoleiomyoma due to its rarity and its association with a serous adenocarcinoma in our patient.","PeriodicalId":90463,"journal":{"name":"Case reports in clinical pathology","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-06-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43989579","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Death by cat bite: Pasteurella multocida: Autopsy findings and review of the literature 猫咬伤致死:多杀性巴氏杆菌:尸检结果和文献综述
Case reports in clinical pathology Pub Date : 2020-06-21 DOI: 10.5430/crcp.v7n1p11
W. Humphrey, Jessica W. Crothers, A. Stowman, S. Mount
{"title":"Death by cat bite: Pasteurella multocida: Autopsy findings and review of the literature","authors":"W. Humphrey, Jessica W. Crothers, A. Stowman, S. Mount","doi":"10.5430/crcp.v7n1p11","DOIUrl":"https://doi.org/10.5430/crcp.v7n1p11","url":null,"abstract":"Pasteurella multocida, a gram-negative bacillus, is present in the oropharyngeal secretions of livestock, wild animals, and domesticated pets and can cause infection in humans. The most common route of entry has been shown to be via an animal bite, but a significant portion of cases of human infection lack evidence of such a wound. Review of the literature reveals that patients with a history of an animal bite tend to have a less aggressive clinical course than patients without an animal source of infection.  We present a case, however, of Pasteurella multocida bacteremia which resulted in the death of an immunocompromised 80-year old woman in which the route of infection was found at autopsy to be a cat bite. This case highlights the importance of educating patients, particularly those with underlying immunocompromised conditions, of the possible lethal complications that can result from animal inflicted wounds and the importance of seeking medical assistance should a bite occur.","PeriodicalId":90463,"journal":{"name":"Case reports in clinical pathology","volume":"7 1","pages":"11"},"PeriodicalIF":0.0,"publicationDate":"2020-06-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42089514","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Cauda equina syndrome due to Factor Xa inhibitor (Rivaroxaban): Case report and review of literature Xa因子抑制剂(利伐沙班)引起的马尾综合征:病例报告及文献复习
Case reports in clinical pathology Pub Date : 2020-01-15 DOI: 10.5430/crcp.v7n1p7
S. Gowda, P. O'Hagan, J. Griffiths
{"title":"Cauda equina syndrome due to Factor Xa inhibitor (Rivaroxaban): Case report and review of literature","authors":"S. Gowda, P. O'Hagan, J. Griffiths","doi":"10.5430/crcp.v7n1p7","DOIUrl":"https://doi.org/10.5430/crcp.v7n1p7","url":null,"abstract":"Background: Factor Xa inhibitors are widely used by the physicians to reduce the incidence of thrombosis in order to protect the cardiovascular function. Although complications of bleeding and spontaneous gastrointestinal sources have been reported before, there are very sporadic cases of spinal epidural haematoma causing neurological compromise. Case presentation: We report a case of spontaneous spinal epidural haematoma (SSEH) in an 85-year-old female patient treated with Rivaroxaban, a new agent to prevent the incidence of thrombo-embolic events. Anticoagulant therapy is a recognised risk factor in the development of spontaneous bleeding and haematomas. The patient presented to the emergency department with sudden onset of severe back pain in the lumbar spine associated with paraplegia in the lower limbs. Magnetic resonance imaging (MRI) of the spine demonstrated a SSEH from T12 to L5 affecting the cauda equina. Rivaroxaban was discontinued and the patient was monitored as an inpatient. There was gradual improvement in the symptoms of the lower limbs. Conclusion: This rare condition of incomplete cauda equina syndrome due to Rivaroxaban therapy has not been reported previously. Clinicians must have a high index of suspicion in patients on regular anti-coagulation regimen.","PeriodicalId":90463,"journal":{"name":"Case reports in clinical pathology","volume":"7 1","pages":"7"},"PeriodicalIF":0.0,"publicationDate":"2020-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.5430/crcp.v7n1p7","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47992963","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Invasive intracystic papillary carcinoma of the male breast: A case report of a 79 year male with advanced breast cancer at presentation 男性乳腺浸润性囊内乳头状癌:一例79岁男性晚期乳腺癌的病例报告
Case reports in clinical pathology Pub Date : 2019-12-23 DOI: 10.5430/crcp.v7n1p1
Der Muonir Edmund, Bandoh Jd, M. Robilu, G. Mainatu, M. Kyereh
{"title":"Invasive intracystic papillary carcinoma of the male breast: A case report of a 79 year male with advanced breast cancer at presentation","authors":"Der Muonir Edmund, Bandoh Jd, M. Robilu, G. Mainatu, M. Kyereh","doi":"10.5430/crcp.v7n1p1","DOIUrl":"https://doi.org/10.5430/crcp.v7n1p1","url":null,"abstract":"Published data on male breast cancers (MBCs) are scare in Ghana. We report a case of breast cancer in a 79-year old man, who presented at the Tamale Teaching surgical unit with a clinically advanced stage of the disease. He had modifified mastectomy and an invasive intracystic papillary cancer was diagnosed histologically. Immunohistochemically, this tumour was ER+/PR+ /HER2-However, hormonal therapy could not be started, for the 79-year old before he died in the third week after being discharge from the hospital.","PeriodicalId":90463,"journal":{"name":"Case reports in clinical pathology","volume":"7 1","pages":"1"},"PeriodicalIF":0.0,"publicationDate":"2019-12-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.5430/crcp.v7n1p1","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47434120","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Paravaginal female adnexal tumor of probable Wolffian origin mimicking vaginal spindle cell epithelioma on biopsy 阴道旁女性附件肿瘤,可能为Wolffian来源,活检时模拟阴道梭形细胞上皮瘤
Case reports in clinical pathology Pub Date : 2019-11-24 DOI: 10.5430/crcp.v6n1p32
R. Yu, B. Courteau, R. Rebello, A. Lytwyn, M. Sur, S. Alowami
{"title":"Paravaginal female adnexal tumor of probable Wolffian origin mimicking vaginal spindle cell epithelioma on biopsy","authors":"R. Yu, B. Courteau, R. Rebello, A. Lytwyn, M. Sur, S. Alowami","doi":"10.5430/crcp.v6n1p32","DOIUrl":"https://doi.org/10.5430/crcp.v6n1p32","url":null,"abstract":"Female adnexal tumor of probable wolffian origin (FATWO) is a tumor of low malignant potential that arises predominantly in the broad ligament, mesosalpinx, and ovarian hilus. The rarity of FATWO increases its susceptibility to misdiagnosis as other tumors, especially when it occurs at an unusual site. We report a 29-year-old woman with a 7.2 cm left paravaginal FATWO that invaded into the vaginal lumen. The initial biopsy demonstrated features suggestive of vaginal spindle cell epithelioma, but with increased Ki67 proliferation index. Pathologists should be aware that the common sieve-like architecture of FATWO may not be apparent on small biopsies, which by sampling error may demonstrate predominantly the less common spindle cell architecture. Awareness of FATWO in the differential diagnosis of paravaginal tumors may help to avoid misinterpretation as vaginal spindle cell epithelioma, a previously unappreciated pitfall in the diagnosis of FATWO.","PeriodicalId":90463,"journal":{"name":"Case reports in clinical pathology","volume":"6 1","pages":"32"},"PeriodicalIF":0.0,"publicationDate":"2019-11-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44381998","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Spiradenoma of the breast and review of cases over 76-years 乳腺螺旋腺瘤及76年以上病例回顾
Case reports in clinical pathology Pub Date : 2019-11-24 DOI: 10.5430/crcp.v6n1p38
M. Dick, Apporva Sharma, Poonam K Sharma
{"title":"Spiradenoma of the breast and review of cases over 76-years","authors":"M. Dick, Apporva Sharma, Poonam K Sharma","doi":"10.5430/crcp.v6n1p38","DOIUrl":"https://doi.org/10.5430/crcp.v6n1p38","url":null,"abstract":"Spiradenomas stem from eccrine and apocrine glands to form benign cutaneous tumors. When arising on the breast, nipple, and areola region, spiradenomas can be difficult to differentiate from more worrisome breast masses. This is particularly true in patients with a prior history of breast cancer. These tumors can be mimicked by a wide range of adnexal growths and play a role in syndromic conditions. We present a case of a 56-year-old female with a 20-year enlarging left lower inner quadrant breast mass reviewed on mammography which was later excised and histopathologically diagnosed as a spiradenoma. Spiradenomas can be challenging to diagnose as they can present with similar findings on inexpensive and non-invasive testing such as ultrasound and mammogram. While a biopsy is a definitive tool for diagnosis, this is contraindicated in some spiradenoma mimickers such as epidermal cysts complicating diagnosis. To our knowledge, there are only six case reports of breast spiradenomas. We have reviewed the histopathology of this case and summarized all cases of breast spiradenomas and their malignant counterpart spiradenocarcinomas available in the literature compiling their presentations and imaging findings.","PeriodicalId":90463,"journal":{"name":"Case reports in clinical pathology","volume":"6 1","pages":"38"},"PeriodicalIF":0.0,"publicationDate":"2019-11-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49024966","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Brown tumour in the cervical spine : Case report and review of literature 颈椎褐色肿瘤病例报告及文献复习
Case reports in clinical pathology Pub Date : 2019-10-30 DOI: 10.5430/crcp.v6n1p27
S. Carta, A. Chungh, S. Gowda, E. Synodinou, P. Sauvé, J. Harvey
{"title":"Brown tumour in the cervical spine : Case report and review of literature","authors":"S. Carta, A. Chungh, S. Gowda, E. Synodinou, P. Sauvé, J. Harvey","doi":"10.5430/crcp.v6n1p27","DOIUrl":"https://doi.org/10.5430/crcp.v6n1p27","url":null,"abstract":"Background: Brown tumour of the cervical spine is very rare and is formed due to focal altered bone remodelling secondary to persistent and uncontrolled primary or secondary hyperparathyroidism. It is considered an extreme form of osteitis fibrosa cystica that occurs in the settings of persistently elevated parathyroid hormone.Case Report: This a unique lesion presented in a 48 year old male with recurrent bone pain and known End Stage Renal Disease (ESRD) on maintenance haemodialysis. The main clinical complaints were weak and painful legs and the initial presentation was after the patient collapsed at home and fractured spinal level C2. The initial assessment included blood tests and radiological imaging. CT scanning of the spine revealed a destructive lytic lesion with loss of height and architectural changes of the C2 vertebral body and cord compression.  The differentials included an acute fracture, a metastatic lesion and Brown’s tumour.  Further imaging with an MRI of the spine and PET-CT were performed which confirmed the above lesion and excluded metastatic disease and bone marrow infiltration. A CT guided bone biopsy followed. The patient continued to receive medical treatment for secondary hyperparathyroidism and the C2 fracture was managed with orthosis through a protective hard collar.Discussion: An up to date literature review revealed very few cases of Brown tumour of the cervical spine and there was only one previous case with C2 involvement due to primary hyperparathyroidism and one due to secondary hyperparathyroidism.  Clinicians must be aware of the varied presentations of Brown’s tumour to identify and provide the appropriate management. ","PeriodicalId":90463,"journal":{"name":"Case reports in clinical pathology","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41640322","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Unexpected death secondary to streptococcus salivarius endocarditis 涎腺链球菌心内膜炎所致意外死亡
Case reports in clinical pathology Pub Date : 2019-10-19 DOI: 10.5430/crcp.v6n1p23
B. Huston, Victor Froloff, K. Mills, M. McGee
{"title":"Unexpected death secondary to streptococcus salivarius endocarditis","authors":"B. Huston, Victor Froloff, K. Mills, M. McGee","doi":"10.5430/crcp.v6n1p23","DOIUrl":"https://doi.org/10.5430/crcp.v6n1p23","url":null,"abstract":"A 51-year old male with a medical history of chronic ethanol and tobacco use was complaining of difficulty breathing and was driven to the local emergency department where he was noted to be in respiratory distress.  The decedent had not seen a physician in over ten years.  The decedent was undergoing an ultrasound to evaluate for a lower extremity deep venous thrombosis when he arrested.  He was unable to be resuscitated.  An autopsy was performed.  The external examination revealed numerous petechial type hemorrhages of the skin with prominence of the arms and lower legs.  Internal examination revealed cardiomegaly (heart weight 720 grams) with left ventricular hypertrophy and prominent endocarditis of the mitral and aortic valves.   Infarcts were noted involving the right kidney and the spleen.  A postmortem blood culture grew Streptococcus salivarius in both the aerobic and anaerobic culture bottles.  ","PeriodicalId":90463,"journal":{"name":"Case reports in clinical pathology","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-10-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48869987","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Coinfection and delayed diagnosis of visceral leishmaniasis: Died predecessors factors 合并感染和内脏利什曼病的延迟诊断:死亡的前驱因素
Case reports in clinical pathology Pub Date : 2019-08-10 DOI: 10.5430/CRCP.V6N1P19
Jaciel de Oliveira Clementino, Daniel Gallina Martins Abrahão, M. S. C. L. Lima Júnior, Herintha Coeto Neitzke Abreu
{"title":"Coinfection and delayed diagnosis of visceral leishmaniasis: Died predecessors factors","authors":"Jaciel de Oliveira Clementino, Daniel Gallina Martins Abrahão, M. S. C. L. Lima Júnior, Herintha Coeto Neitzke Abreu","doi":"10.5430/CRCP.V6N1P19","DOIUrl":"https://doi.org/10.5430/CRCP.V6N1P19","url":null,"abstract":"Visceral leishmaniasis (VL) is an anthropozoonosis caused by Leishmania infantum in most Brazilian states and is known for its significant lethality resulting from improper diagnosis and treatment. VL is difficult to diagnose because its clinical manifestations and laboratory abnormalities are analogous to several other pathologies. We report a case of a 54-year-old man, negative for Human Immunodeficiency Virus (HIV), with VL who was initially diagnosed with anemia, consumptive syndrome, pneumonia, chronic obstructive pulmonary disease, and septic shock and died due to a delayed diagnosis of VL. ","PeriodicalId":90463,"journal":{"name":"Case reports in clinical pathology","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-08-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.5430/CRCP.V6N1P19","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47490771","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Angiosarcoma arising in a neurofibromatosis-1 patient as a de novo malignancy? 血管肉瘤发生于神经纤维瘤病-1患者作为新发恶性肿瘤?
Case reports in clinical pathology Pub Date : 2019-07-26 DOI: 10.5430/CRCP.V6N1P13
X. Dubernard, B. Pham, M. Pluot, Y. Renard, M. Labrousse
{"title":"Angiosarcoma arising in a neurofibromatosis-1 patient as a de novo malignancy?","authors":"X. Dubernard, B. Pham, M. Pluot, Y. Renard, M. Labrousse","doi":"10.5430/CRCP.V6N1P13","DOIUrl":"https://doi.org/10.5430/CRCP.V6N1P13","url":null,"abstract":"Background: Neurofibromatosis-1 (NF-1) is the most common genetic disease belonging to the group of neural tissue cell growth disorders, known to be complicated by malignant peripheral nerve sheath tumors or MPNST. On the contrary, angiosarcoma is rarely associated with NF-1. Only few cases reported angiosarcoma arising as a sarcomatous transformation within a preexisting MPNST.Methods and results: We report here the remarkable case of a 35-year-old NF-1 woman, with a history of excised MPNST 8 years before a new hospitalization for the development of multi localized angiosarcoma, whose discovery is related to an oropharyngeal involvement, with a dramatic presentation. Review of the literature and differences from previous reports are discussed.Conclusion: Our case report supports the hypothesis of an angiosarcoma developing as a malignant proliferation apparently not arising from contiguous neurofibroma or MPNST lesions, but representing a second de novo malignancy.","PeriodicalId":90463,"journal":{"name":"Case reports in clinical pathology","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-07-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.5430/CRCP.V6N1P13","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43708929","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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