Case reports in clinical pathology最新文献

On a Complex Biphasic Neoplasm Involving the Ovary and Omentum Expressing Neuroendocrine Markers, HBME1 and TTF1: A Case Report and the Literature Review 表达神经内分泌标志物HBME1和TTF1累及卵巢和网膜的复杂双相肿瘤1例报告及文献复习

Case reports in clinical pathology Pub Date : 2023-09-24 DOI: 10.5430/crcp.v10n1p1

Giuseppe Albonico, Marcello Filotico

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Inflammatory myofibroblastic tumor of the ureter in a paediatric patient 儿童输尿管炎性肌纤维母细胞瘤

Case reports in clinical pathology Pub Date : 2022-08-28 DOI: 10.5430/crcp.v9n1p27

Zehra Kazmi, Fatima Ambreen, U. Tahir, S. Zafar Zaidi

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Polymorphous adenocarcinoma of the breast: A case report 乳腺多形性腺癌1例报告

Case reports in clinical pathology Pub Date : 2022-07-25 DOI: 10.5430/crcp.v9n1p24

Ivan Franin, Sanda Bubanović, I. Milas, K. Čulo, M. Kirigin

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Multiple retroperitoneal cystic lymphangiomas in a pregnant woman: A case report 一例孕妇腹膜后多发囊性淋巴管瘤

Case reports in clinical pathology Pub Date : 2022-07-25 DOI: 10.5430/crcp.v9n1p20

Janriette Isabelle Vizuete Yépez, Marcelo Xavier Carpio Ayora, A. Robin, Evelyn Carolina Polanco Jacome

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A rare case of mucoepidermoid carcinoma of the skin: A case report and a literature review 皮肤黏液表皮样癌1例报告并文献复习

Case reports in clinical pathology Pub Date : 2021-11-24 DOI: 10.5430/crcp.v9n1p1

M. Filotico, Francesca Mazzeo

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A confluence of rarities: post sedation neuroexcitation following adrenal perineurioma resection 罕见病例的汇合：肾上腺会阴肿瘤切除术后镇静后神经兴奋

Case reports in clinical pathology Pub Date : 2021-11-08 DOI: 10.5430/crcp.v8n1p40

Vivek Somasundaram, M. Hernandez, Blake A Ebner, A. Folpe, Joaquín J. García, T. Mckenzie

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Nodal mycobacterial spindle cell pseudotumor: A diagnostic pitfall 结节分枝杆菌梭形细胞假瘤:一个诊断缺陷

Case reports in clinical pathology Pub Date : 2021-10-14 DOI: 10.5430/crcp.v8n1p33

Daniel Christensen, E. Gnass, G. Uppal

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Meningitis caused by Streptococcus suis 由猪链球菌引起的脑膜炎

Case reports in clinical pathology Pub Date : 2021-07-24 DOI: 10.5430/CRCP.V8N1P23

S. Oeng, Lath Sokun, Veasna Tan, N. Townell, E. Baron, J. Letchford

{"title":"Meningitis caused by Streptococcus suis","authors":"S. Oeng, Lath Sokun, Veasna Tan, N. Townell, E. Baron, J. Letchford","doi":"10.5430/CRCP.V8N1P23","DOIUrl":"https://doi.org/10.5430/CRCP.V8N1P23","url":null,"abstract":"Background: In most countries with full-service microbiology services, streptococcus-like organisms visualized in a gram-stained smear of cerebrospinal fluid (CSF) from patients presenting with meningitis syndrome would be assumed to be Streptococcus pneumoniae . However, in many areas of the world, predominantly in Southeast Asia, the organism may be Streptococcus suis . Although initial antimicrobial treatment is similar, additional treatment for specific co-morbidities, such as hearing loss, may be needed. This case, involving an adult male who presented with signs and symptoms of meningitis, describes the appropriate laboratory test procedures used to make the diagnosis and the subsequent patient management strategy. Case presentation : A previously healthy 69-year old rice farmer was admitted to the hospital with a one day history of fever, headache, neck stiffness, and altered consciousness. Initial laboratory studies were consistent with meningitis but the CSF Gram stain did not reveal any organisms. Blood cultures obtained at admission grew alpha-hemolytic, optochin-resistant colonies consistent with Streptococcus suis, and the identification was confirmed by MALDI-TOF performed at another laboratory. Unusually, the isolate was penicillin resistant. The patient received 4 mg/day ceftriaxone and dexamethasone (to mitigate deafness) for 10 days and was discharged to home with moderate deafness but no residual infection. Conclusion: Diagnosis of meningitis should include both blood cultures and CSF cultures obtained before any antibiotics are administered. In some patient populations such as those in Southeast Asia or if there is history of contact with pigs or raw pork, S. suis should be considered.","PeriodicalId":90463,"journal":{"name":"Case reports in clinical pathology","volume":"8 1","pages":"23"},"PeriodicalIF":0.0,"publicationDate":"2021-07-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42179409","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Epithelioid angiosarcoma of the small intestine presenting with intractable gastrointestinal bleeding: An uncommon tumor with diagnostic challenge and poor prognosis 小肠上皮样血管肉瘤表现为难治性胃肠道出血:一种罕见的肿瘤，诊断困难，预后差

Case reports in clinical pathology Pub Date : 2021-07-01 DOI: 10.5430/CRCP.V8N1P17

C. Onyenekwu, Reena Singh, J. A. Miller, M. Mostafa

{"title":"Epithelioid angiosarcoma of the small intestine presenting with intractable gastrointestinal bleeding: An uncommon tumor with diagnostic challenge and poor prognosis","authors":"C. Onyenekwu, Reena Singh, J. A. Miller, M. Mostafa","doi":"10.5430/CRCP.V8N1P17","DOIUrl":"https://doi.org/10.5430/CRCP.V8N1P17","url":null,"abstract":"Introduction: Angiosarcoma of the gastrointestinal tract is a rare, aggressive malignant neoplasm of vascular origin. Commonly, this tumor occurs due to metastases from other sites like the head and neck region and the soft tissue. When occurring as a primary tumor of the intestines, this entity poses a diagnostic dilemma due to its non-specific clinical presentation, coupled to its infiltrative features that may occur without an obvious lesion amenable to routine gastrointestinal interventions. The findings from an autopsy and surgical case with a brief review of its diagnostic features and relevant literature are discussed.Methods: We present a 73-year-old male with a history of a recent onset of gastrointestinal bleeding who was referred to our facility for persisting bleeding. He underwent endoscopy without an identifiable source of bleeding and subsequently received a colectomy at our facility, with repeated blood transfusions for persisting gastrointestinal bleeding. He was eventually transitioned to hospice and died shortly after presentation. A complete autopsy was performed.Results: There was anasarca with hemoperitoneum and intestinal intraluminal blood. Present in the small intestinal mucosa were three hemorrhagic nodules. Histologically, the nodules demonstrated medium to large epithelioid vasoformative neoplastic cells infiltrating through the wall of the small intestine and extending to the omentum. The findings from the gross and histology examination, as well as the immunohistochemical stains were consistent with an epithelioid angiosarcoma.Conclusion: Primary epithelioid angiosarcoma of the intestine is an uncommon aggressive tumor that poses a diagnostic challenge. Although rare, this diagnosis needs to be considered in patients with intractable gastrointestinal bleeding. Due to its morphologic overlap with other benign and malignant neoplasms, the use of ancillary testing during histologic examination is key in arriving at an accurate diagnosis.","PeriodicalId":90463,"journal":{"name":"Case reports in clinical pathology","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42427794","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Anaplastic pilocytic astrocytoma of the cerebellum presenting with conus medullaris drop metastasis 小脑间变性毛细胞星形细胞瘤表现为髓圆锥滴转移

Case reports in clinical pathology Pub Date : 2021-05-12 DOI: 10.5430/CRCP.V8N1P10

Jared Sweeney, Vaibhav Chumbalkar, Michael D. Staudt, P. Entezami, J. Qian, V. Sukul

{"title":"Anaplastic pilocytic astrocytoma of the cerebellum presenting with conus medullaris drop metastasis","authors":"Jared Sweeney, Vaibhav Chumbalkar, Michael D. Staudt, P. Entezami, J. Qian, V. Sukul","doi":"10.5430/CRCP.V8N1P10","DOIUrl":"https://doi.org/10.5430/CRCP.V8N1P10","url":null,"abstract":"Due to its rarity, a complete understanding of the clinical behavior, pathogenesis, and diagnostic definition of anaplastic pilocytic astrocytoma (APA) is currently lacking. The optimal clinical management and use of adjuvant therapies has yet to be defined. We present a 64 year-old-female with progressive headaches, dysarthria, and ataxia, who was found to have right cerebellar mass. A gross total resection was achieved through two staged operations. Pathology demonstrated focal areas of necrosis, tumor infiltration, and increased mitotic activity most consistent with APA. Adjuvant chemotherapy and stereotactic radiosurgery were administered. Approximately two years later, the patient presented with symptoms of cauda equina syndrome, and lumbar spine imaging demonstrated a large intradural mass at the conus medullaris with diffuse leptomeningeal enhancement. A biopsy was performed and was consistent with metastatic APA. APA may rarely progress to metastatic disease, most frequently involving the leptomeninges of the posterior fossa and cervical spine. This report represents the first case of metastases distal to the cervicomedullary junction.","PeriodicalId":90463,"journal":{"name":"Case reports in clinical pathology","volume":"8 1","pages":"10"},"PeriodicalIF":0.0,"publicationDate":"2021-05-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46527231","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0