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Neural and emotional responses to mood induction and emotional design in multimedia learning. 多媒体学习中情绪诱导和情绪设计的神经和情绪反应。
IF 2.3 4区 医学
BMC Neuroscience Pub Date : 2026-04-27 DOI: 10.1186/s12868-026-01006-5
Duygu Mutlu-Bayraktar, Ahmet Murat Uzun, Bulent Yilmaz
{"title":"Neural and emotional responses to mood induction and emotional design in multimedia learning.","authors":"Duygu Mutlu-Bayraktar, Ahmet Murat Uzun, Bulent Yilmaz","doi":"10.1186/s12868-026-01006-5","DOIUrl":"https://doi.org/10.1186/s12868-026-01006-5","url":null,"abstract":"","PeriodicalId":9031,"journal":{"name":"BMC Neuroscience","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2026-04-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147761118","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Preventive effect of PC-SOD on oxaliplatin-induced peripheral neuropathy in rats. PC-SOD对奥沙利铂所致大鼠周围神经病变的预防作用。
IF 2.3 4区 医学
BMC Neuroscience Pub Date : 2026-04-22 DOI: 10.1186/s12868-026-01004-7
Zhiwei Qiao, Yuki Uchihara, Naohiro Tsukiyama, Shota Akimoto, Noriko Kaji, Koichiro Fukuda, Tohru Mizushima
{"title":"Preventive effect of PC-SOD on oxaliplatin-induced peripheral neuropathy in rats.","authors":"Zhiwei Qiao, Yuki Uchihara, Naohiro Tsukiyama, Shota Akimoto, Noriko Kaji, Koichiro Fukuda, Tohru Mizushima","doi":"10.1186/s12868-026-01004-7","DOIUrl":"https://doi.org/10.1186/s12868-026-01004-7","url":null,"abstract":"","PeriodicalId":9031,"journal":{"name":"BMC Neuroscience","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2026-04-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147761136","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Pretreatment with the psychedelic DOI mitigates LPS-induced hippocampal inflammation and behavioral impairments in mice. 迷幻DOI预处理可减轻lps诱导的小鼠海马炎症和行为障碍。
IF 2.3 4区 医学
BMC Neuroscience Pub Date : 2026-03-24 DOI: 10.1186/s12868-026-01003-8
Michael Fiorillo, Javier González-Maeso
{"title":"Pretreatment with the psychedelic DOI mitigates LPS-induced hippocampal inflammation and behavioral impairments in mice.","authors":"Michael Fiorillo, Javier González-Maeso","doi":"10.1186/s12868-026-01003-8","DOIUrl":"10.1186/s12868-026-01003-8","url":null,"abstract":"","PeriodicalId":9031,"journal":{"name":"BMC Neuroscience","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2026-03-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13126789/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147503185","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Milk-derived miR-126-3p-loaded small extracellular vesicles attenuate amyloid-β-induced cellular stress in a neuroblastoma cell model. 在神经母细胞瘤细胞模型中，乳源性负载mir -126-3p的细胞外小泡可减弱淀粉样蛋白β诱导的细胞应激。
IF 2.3 4区 医学
BMC Neuroscience Pub Date : 2026-03-16 DOI: 10.1186/s12868-026-01002-9
Sinan Gönüllü, Şeyma Aydın, Hamit Çelik, Oğuz Çelik, Sefa Küçükler, Ahmet Topal, Ramazan Akay, Mustafa Onur Yıldız, Bülent Alım, Selçuk Özdemir
{"title":"Milk-derived miR-126-3p-loaded small extracellular vesicles attenuate amyloid-β-induced cellular stress in a neuroblastoma cell model.","authors":"Sinan Gönüllü, Şeyma Aydın, Hamit Çelik, Oğuz Çelik, Sefa Küçükler, Ahmet Topal, Ramazan Akay, Mustafa Onur Yıldız, Bülent Alım, Selçuk Özdemir","doi":"10.1186/s12868-026-01002-9","DOIUrl":"10.1186/s12868-026-01002-9","url":null,"abstract":"","PeriodicalId":9031,"journal":{"name":"BMC Neuroscience","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2026-03-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13104434/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147466997","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Identification of the IL-1β/miRNA-326 axis as a key regulator of ferroptosis in spinal cord injury. IL-1β/miRNA-326轴在脊髓损伤中作为铁上吊关键调控因子的鉴定
IF 2.3 4区 医学
BMC Neuroscience Pub Date : 2026-03-02 DOI: 10.1186/s12868-026-01001-w
Senming Xu, Yangyang Jiang, Yuchang Gui, Jianmin Chen, Qinhe Pan, Minli Jiang, Jianwen Xu
{"title":"Identification of the IL-1β/miRNA-326 axis as a key regulator of ferroptosis in spinal cord injury.","authors":"Senming Xu, Yangyang Jiang, Yuchang Gui, Jianmin Chen, Qinhe Pan, Minli Jiang, Jianwen Xu","doi":"10.1186/s12868-026-01001-w","DOIUrl":"10.1186/s12868-026-01001-w","url":null,"abstract":"","PeriodicalId":9031,"journal":{"name":"BMC Neuroscience","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2026-03-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13059498/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147343560","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Involvement of CB1 cannabinoid receptors in methamphetamine-related decision-making and social behavior deficits. CB1大麻素受体参与甲基苯丙胺相关决策和社会行为缺陷。
IF 2.3 4区 医学
BMC Neuroscience Pub Date : 2026-02-23 DOI: 10.1186/s12868-026-01000-x
Tahoora Mousavi, Nadia Hatami, Saba Niknamfar, Mahshid Naseri, Raheleh Rafaiee, Seyedeh Masoumeh Seyedhosseini Tamijani, Mohammad Saleh Ranaiy, Hamed Ghazvini
{"title":"Involvement of CB1 cannabinoid receptors in methamphetamine-related decision-making and social behavior deficits.","authors":"Tahoora Mousavi, Nadia Hatami, Saba Niknamfar, Mahshid Naseri, Raheleh Rafaiee, Seyedeh Masoumeh Seyedhosseini Tamijani, Mohammad Saleh Ranaiy, Hamed Ghazvini","doi":"10.1186/s12868-026-01000-x","DOIUrl":"10.1186/s12868-026-01000-x","url":null,"abstract":"","PeriodicalId":9031,"journal":{"name":"BMC Neuroscience","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2026-02-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13037093/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147275716","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Slc6a9 is distributed in glial cells and neurons across several nervous system regions, whereas Slc6a5 is more restricted to neurons in the caudal brain. Slc6a9分布在多个神经系统区域的神经胶质细胞和神经元中，而Slc6a5则更多地局限于脑尾侧的神经元。
IF 2.3 4区 医学
BMC Neuroscience Pub Date : 2026-02-17 DOI: 10.1186/s12868-026-00999-3
Mikaela M Ceder, Malin C Lagerström
{"title":"Slc6a9 is distributed in glial cells and neurons across several nervous system regions, whereas Slc6a5 is more restricted to neurons in the caudal brain.","authors":"Mikaela M Ceder, Malin C Lagerström","doi":"10.1186/s12868-026-00999-3","DOIUrl":"10.1186/s12868-026-00999-3","url":null,"abstract":"","PeriodicalId":9031,"journal":{"name":"BMC Neuroscience","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2026-02-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12931055/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146212005","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Acetyl-11-keto-β-boswellic acid attenuates tau oligomer-induced neurotoxicity in neuroblastoma cell model. 乙酰-11-酮-β-乳香酸在神经母细胞瘤细胞模型中减弱tau寡聚物诱导的神经毒性。
IF 2.3 4区 医学
BMC Neuroscience Pub Date : 2026-02-12 DOI: 10.1186/s12868-026-00996-6
Shahnaz Pourhossein, Ibrahim Bahrami Mianrood, Seyyed Hossein Khatami, Sajad Ehtiati, Majid Ghasemian, Farzad Mokhtari, Reyhane Ahmadzade, Marziyeh Goudarzi, Nastaran Hamed, Fatemeh Namvarjah, Saeed Karima
{"title":"Acetyl-11-keto-β-boswellic acid attenuates tau oligomer-induced neurotoxicity in neuroblastoma cell model.","authors":"Shahnaz Pourhossein, Ibrahim Bahrami Mianrood, Seyyed Hossein Khatami, Sajad Ehtiati, Majid Ghasemian, Farzad Mokhtari, Reyhane Ahmadzade, Marziyeh Goudarzi, Nastaran Hamed, Fatemeh Namvarjah, Saeed Karima","doi":"10.1186/s12868-026-00996-6","DOIUrl":"10.1186/s12868-026-00996-6","url":null,"abstract":"<p><strong>Background: </strong>Alzheimer's disease (AD) is a progressive neurodegenerative disorder characterized by microtubule destabilization, neuroinflammation, and tau pathology. Among the proposed therapeutic approaches, acetyl-11-keto-β-boswellic acid (AKBA), a bioactive triterpene from Boswellia serrata, has gained attention due to its multiple neuroprotective mechanisms, including microtubule stabilization, anti-inflammatory activity, antioxidant effects, and promotion of neurogenesis. In this study, we aimed to investigate the neuroprotective effect of AKBA against tau oligomer-induced cytotoxicity in SH-SY5Y neuroblastoma cells.</p><p><strong>Results: </strong>Recombinant human tau protein was expressed, purified, and oligomerized, and the formation of oligomers was confirmed by thioflavin T fluorescence and dynamic light scattering (DLS). SH-SY5Y cells were then treated with AKBA and exposed to tau oligomers. Cell viability was assessed via MTT assay, and apoptosis was evaluated by flow cytometry. The morphology of tau aggregates was visualized using transmission electron microscopy.</p><p><strong>Conclusions: </strong>Our findings demonstrated that AKBA significantly reduced tau oligomer-induced cytotoxicity and enhanced cell viability. These results suggest that AKBA, through its multifaceted protective mechanisms, holds promise as a potential therapeutic agent for the treatment of tauopathies such as Alzheimer's disease.</p><p><strong>Clinical trial number: </strong>Not applicable.</p>","PeriodicalId":9031,"journal":{"name":"BMC Neuroscience","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2026-02-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12998064/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146177962","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
MEF2A-mediated inhibition of ischemic stroke injury via the PI3K/AKT pathway: a comprehensive bioinformatics and in vitro study. mef2a介导的PI3K/AKT通路对缺血性脑卒中损伤的抑制：一项综合生物信息学和体外研究
IF 2.3 4区 医学
BMC Neuroscience Pub Date : 2026-02-02 DOI: 10.1186/s12868-026-00997-5
Tingyu Zhang, Jiaqi Cheng, Yushi Tian, Ying Hai
{"title":"MEF2A-mediated inhibition of ischemic stroke injury via the PI3K/AKT pathway: a comprehensive bioinformatics and in vitro study.","authors":"Tingyu Zhang, Jiaqi Cheng, Yushi Tian, Ying Hai","doi":"10.1186/s12868-026-00997-5","DOIUrl":"10.1186/s12868-026-00997-5","url":null,"abstract":"","PeriodicalId":9031,"journal":{"name":"BMC Neuroscience","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2026-02-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12954911/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146099752","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Modulation of stress and neuroplasticity biomarkers via rhythmic vocalization: a controlled study on NDNF, cortisol, and monoamines. 通过有节奏的发声调节压力和神经可塑性生物标志物：一项对NDNF、皮质醇和单胺的对照研究。
IF 2.3 4区 医学
BMC Neuroscience Pub Date : 2026-01-29 DOI: 10.1186/s12868-026-00998-4
Süheyb Okur, Bülent Bayraktar
{"title":"Modulation of stress and neuroplasticity biomarkers via rhythmic vocalization: a controlled study on NDNF, cortisol, and monoamines.","authors":"Süheyb Okur, Bülent Bayraktar","doi":"10.1186/s12868-026-00998-4","DOIUrl":"10.1186/s12868-026-00998-4","url":null,"abstract":"","PeriodicalId":9031,"journal":{"name":"BMC Neuroscience","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2026-01-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12924569/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146084179","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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