BMC Neuroscience最新文献

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Retraction Note: 27-Hydroxycholesterol increases α-synuclein protein levels through proteasomal inhibition in human dopaminergic neurons. 撤稿说明:27-羟基胆固醇通过蛋白酶体抑制作用增加人多巴胺能神经元中的α-突触核蛋白水平。
IF 2.4 4区 医学
BMC Neuroscience Pub Date : 2024-11-07 DOI: 10.1186/s12868-024-00910-y
Jared Schommer, Gurdeep Marwarha, Trevor Schommer, Travis Flick, Jonah Lund, Othman Ghribi
{"title":"Retraction Note: 27-Hydroxycholesterol increases α-synuclein protein levels through proteasomal inhibition in human dopaminergic neurons.","authors":"Jared Schommer, Gurdeep Marwarha, Trevor Schommer, Travis Flick, Jonah Lund, Othman Ghribi","doi":"10.1186/s12868-024-00910-y","DOIUrl":"https://doi.org/10.1186/s12868-024-00910-y","url":null,"abstract":"","PeriodicalId":9031,"journal":{"name":"BMC Neuroscience","volume":null,"pages":null},"PeriodicalIF":2.4,"publicationDate":"2024-11-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142603185","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The cognitive neuroscience and neurocognitive rehabilitation of dance. 舞蹈的认知神经科学和神经认知康复。
IF 2.4 4区 医学
BMC Neuroscience Pub Date : 2024-11-06 DOI: 10.1186/s12868-024-00906-8
Madeleine Eve Hackney, Agnieszka Zofia Burzynska, Lena H Ting
{"title":"The cognitive neuroscience and neurocognitive rehabilitation of dance.","authors":"Madeleine Eve Hackney, Agnieszka Zofia Burzynska, Lena H Ting","doi":"10.1186/s12868-024-00906-8","DOIUrl":"10.1186/s12868-024-00906-8","url":null,"abstract":"<p><p>Creative movement, in the form of music- and dance-based exercise and rehabilitation, can serve as a model for learning and memory, visuospatial orientation, mental imagery, and multimodal sensory-motor integration. This review summarizes the advancement in cognitive neuroscience aimed at determining cognitive processes and brain structural and functional correlates involved in dance or creative movement, as well as the cognitive processes which accompany such activities. We synthesize the evidence for the use of cognitive, motor, and cognitive-motor function in dance as well as dance's potential application in neurological therapy and neurorehabilitation. Finally, we discuss how partnered interaction and sensorimotor integration in dance, and \"dancing robots\" could shed light on future application of dance as rehabilitation, of dance used in technology and potential mechanisms of benefit from dance-based activities.</p>","PeriodicalId":9031,"journal":{"name":"BMC Neuroscience","volume":null,"pages":null},"PeriodicalIF":2.4,"publicationDate":"2024-11-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11539675/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142589351","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Learning ballet technique modulates the stretch reflex in students with cerebral palsy: case series. 学习芭蕾舞技巧可调节脑瘫学生的伸展反射:病例系列。
IF 2.4 4区 医学
BMC Neuroscience Pub Date : 2024-11-06 DOI: 10.1186/s12868-024-00873-0
Citlali López-Ortiz, Maxine He, Deborah Gaebler-Spira, Mindy F Levin
{"title":"Learning ballet technique modulates the stretch reflex in students with cerebral palsy: case series.","authors":"Citlali López-Ortiz, Maxine He, Deborah Gaebler-Spira, Mindy F Levin","doi":"10.1186/s12868-024-00873-0","DOIUrl":"10.1186/s12868-024-00873-0","url":null,"abstract":"<p><strong>Background: </strong>Cerebral palsy (CP) is considered the most prevalent developmental motor disorder in children. There is a need for training programs that enhance motor abilities and normalize function from an early age. Previous studies report improved motor outcomes in dance interventions for CP. Investigating the neurophysiological mechanisms underlying such improvements is necessary for efficient and safe intervention design. This study reports changes in stretch reflex responses as the primary neurophysiological motor outcome of a targeted ballet class intervention.</p><p><strong>Results: </strong>A case series of participants with mixed spastic and dyskinetic CP (n = 4, mean age = 12.5 years, SD = 6.9S years, three female, one male) who learned ballet technique in a course of one-hour classes twice per week for six weeks is presented. Changes in stretch reflex responses and in clinical motor tests as secondary outcomes were observed after the course and at one-month follow-up. Quantitative measures of elbow or ankle stretch reflex were obtained using electromyography and electrogoniometry. The joint angle of the stretch reflex onset varied across velocities of stretch, and its variability decreased after the intervention. Within-subject tests of the central tendency of stretch reflex angle coefficients of variation and frequency distribution demonstrated significant changes (p-values < 0.05). Secondary outcomes included the Quality of Upper Extremity Skills Test (QUEST), Pediatric Balance Scale (PBS), Modified Tardieu Scale (MTS), Dyskinesia Impairment Scale (DIS), and Selective Control Assessment of the Lower Extremity (SCALE). All the participants demonstrated improvements larger than the minimal clinical important difference (MCID) or the smallest detectable difference (SDD), as applicable.</p><p><strong>Conclusions: </strong>Evidence of changes in the stretch reflex responses in these four cases of mixed CP was observed. The observed variability in the stretch reflex responses may be due to the dyskinetic component of the mixed CP presentations. More studies with a larger sample size and longer duration of learning and practice of ballet technique are necessary to establish the extent of possible modulation and adaptation of the stretch reflex response as a neurophysiological basis for observed improvements in clinical measures.</p><p><strong>Trial registration: </strong>This study was registered in the Clinical Trials Protocol Registration and Results System (NCT04237506, January 17, 2020).</p>","PeriodicalId":9031,"journal":{"name":"BMC Neuroscience","volume":null,"pages":null},"PeriodicalIF":2.4,"publicationDate":"2024-11-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11539840/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142589418","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
APOE4 rat model of Alzheimer's disease: sex differences, genetic risk and diet. 阿尔茨海默病 APOE4 大鼠模型:性别差异、遗传风险和饮食。
IF 2.4 4区 医学
BMC Neuroscience Pub Date : 2024-11-06 DOI: 10.1186/s12868-024-00901-z
Bradley Colarusso, Richard Ortiz, Julian Yeboah, Arnold Chang, Megha Gupta, Praveen Kulkarni, Craig F Ferris
{"title":"APOE4 rat model of Alzheimer's disease: sex differences, genetic risk and diet.","authors":"Bradley Colarusso, Richard Ortiz, Julian Yeboah, Arnold Chang, Megha Gupta, Praveen Kulkarni, Craig F Ferris","doi":"10.1186/s12868-024-00901-z","DOIUrl":"10.1186/s12868-024-00901-z","url":null,"abstract":"<p><p>The strongest genetic risk factor for Alzheimer's disease (AD) is the ε4 allele of apolipoprotein E (ApoE ε4). A high fat diet also adds to the risk of dementia and AD. In addition, there are sex differences as women carriers have a higher risk of an earlier onset and rapid decline in memory than men. The present study looked at the effect of the genetic risk of ApoE ε4 together with a high fat/high sucrose diet (HFD/HSD) on brain function in male and female rats using magnetic resonance imaging. We hypothesized female carriers would present with deficits in cognitive behavior together with changes in functional connectivity as compared to male carriers. Four-month-old wildtype and human ApoE ε4 knock-in (TGRA8960), male and female Sprague Dawley rats were put on a HFD/HSD for four months. Afterwards they were imaged for changes in function using resting state BOLD functional connectivity. Images were registered to, and analyzed, using a 3D MRI rat atlas providing site-specific data on 173 different brain areas. Resting state functional connectivity showed male wildtype had greater connectivity between areas involved in feeding and metabolism while there were no differences between female and male carriers and wildtype females. The data were unexpected. The genetic risk was overshadowed by the diet. Male wildtype rats were most sensitive to the HFD/HSD presenting with a deficit in cognitive performance with enhanced functional connectivity in neural circuitry associated with food consumption and metabolism.</p>","PeriodicalId":9031,"journal":{"name":"BMC Neuroscience","volume":null,"pages":null},"PeriodicalIF":2.4,"publicationDate":"2024-11-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11539573/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142589392","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Tapping into the vocal learning and rhythmic synchronization hypothesis. 挖掘声乐学习和节奏同步假说。
IF 2.4 4区 医学
BMC Neuroscience Pub Date : 2024-11-06 DOI: 10.1186/s12868-024-00863-2
Constantina Theofanopoulou
{"title":"Tapping into the vocal learning and rhythmic synchronization hypothesis.","authors":"Constantina Theofanopoulou","doi":"10.1186/s12868-024-00863-2","DOIUrl":"10.1186/s12868-024-00863-2","url":null,"abstract":"<p><p>In this article, I present three main points that could benefit the \"vocal learning and rhythmic synchronization hypothesis\", encompassing neurogenetic mechanisms of gene expression transmission and single motor neuron function, classification of different behavioral motor phenotypes (e.g., spontaneous vs. voluntary), and other evolutionary considerations (i.e., the involvement of reward mechanisms).</p>","PeriodicalId":9031,"journal":{"name":"BMC Neuroscience","volume":null,"pages":null},"PeriodicalIF":2.4,"publicationDate":"2024-11-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11539701/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142589329","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
De-sync: disruption of synchronization as a key factor in individual and collective creative processes. 去同步化:同步化的破坏是个人和集体创造过程中的一个关键因素。
IF 2.4 4区 医学
BMC Neuroscience Pub Date : 2024-11-06 DOI: 10.1186/s12868-024-00874-z
Julien Laroche, Asaf Bachrach, Lior Noy
{"title":"De-sync: disruption of synchronization as a key factor in individual and collective creative processes.","authors":"Julien Laroche, Asaf Bachrach, Lior Noy","doi":"10.1186/s12868-024-00874-z","DOIUrl":"10.1186/s12868-024-00874-z","url":null,"abstract":"<p><p>Creativity is a key skill for the twenty-first century, where the individual and collective imperative to adapt is omnipresent. Yet, it is still unclear how to put creativity theories into practice, which signals a lacuna in our understanding of the pragmatic means by which we get creative. This paper starts from the identification of a number of gaps in the literature. In particular, individual and group creativity are usually treated separately, and the emphasis on the search for novelty seems to overshadow the importance experts give to the disruption of their habitual patterns of behavior. To overcome these gaps, we propose foundations for a unifying framework that takes the perspective of dynamical systems. Specifically, we suggest that de-synchronization, a hallmark of disruption, is an integral part of the creative processes that operate across individual and collective levels of analysis. We show that by conjuring uncertainty, de-synchronized states provide opportunities for creative reorganization. In order to ground this framework, we survey and discuss existing literature, and focus on group improvisation practices (in particular, music and dance improvisation), where partners use the dynamics of their interaction to bring forth a collective performance in real-time. In these practices, disruption by de-synchronization, termed here as 'problematization of coordination', is a pragmatic approach used to push the creative process forward. We suggest that this approach might also be relevant in other types of individual and collective creative processes.</p>","PeriodicalId":9031,"journal":{"name":"BMC Neuroscience","volume":null,"pages":null},"PeriodicalIF":2.4,"publicationDate":"2024-11-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11539736/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142589409","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The social and neural bases of creative movement: workshop overview. 创造性运动的社会和神经基础:研讨会综述。
IF 2.4 4区 医学
BMC Neuroscience Pub Date : 2024-11-06 DOI: 10.1186/s12868-024-00893-w
Shihab Shamma, Jose Contreras-Vidal, Jonathan Fritz, Soo-Siang Lim, Betty Tuller, Emmeline Edwards, Sunil Iyengar
{"title":"The social and neural bases of creative movement: workshop overview.","authors":"Shihab Shamma, Jose Contreras-Vidal, Jonathan Fritz, Soo-Siang Lim, Betty Tuller, Emmeline Edwards, Sunil Iyengar","doi":"10.1186/s12868-024-00893-w","DOIUrl":"10.1186/s12868-024-00893-w","url":null,"abstract":"<p><p>This editorial provides a background and overview of the interdisciplinary workshop on \"The Social and Neural Bases of Creative Movement,\" bringing together dancers, choreographers, musicians, artists, kinesiologists and neuroscientists to share perspectives and develop a common language to define and explore the relationship between dance and the brain.</p>","PeriodicalId":9031,"journal":{"name":"BMC Neuroscience","volume":null,"pages":null},"PeriodicalIF":2.4,"publicationDate":"2024-11-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11539434/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142589363","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Beat-based dancing to music has evolutionary foundations in advanced vocal learning. 以节拍为基础的音乐舞蹈在高级声乐学习中具有进化基础。
IF 2.4 4区 医学
BMC Neuroscience Pub Date : 2024-11-06 DOI: 10.1186/s12868-024-00843-6
Aniruddh D Patel
{"title":"Beat-based dancing to music has evolutionary foundations in advanced vocal learning.","authors":"Aniruddh D Patel","doi":"10.1186/s12868-024-00843-6","DOIUrl":"10.1186/s12868-024-00843-6","url":null,"abstract":"<p><p>Dancing to music is ancient and widespread in human cultures. While dance shows great cultural diversity, it often involves nonvocal rhythmic movements synchronized to musical beats in a predictive and tempo-flexible manner. To date, the only nonhuman animals known to spontaneously move to music in this way are parrots. This paper proposes that human-parrot similarities in movement to music and in the neurobiology of advanced vocal learning hold clues to the evolutionary foundations of human dance. The proposal draws on recent research on the neurobiology of parrot vocal learning by Jarvis and colleagues and on a recent cortical model for speech motor control by Hickock and colleagues. These two lines of work are synthesized to suggest that gene regulation changes associated with the evolution of a dorsal laryngeal pitch control pathway in ancestral humans fortuitously strengthened auditory-parietal cortical connections that support beat-based rhythmic processing. More generally, the proposal aims to explain how and why the evolution of strong forebrain auditory-motor integration in the service of learned vocal control led to a capacity and proclivity to synchronize nonvocal movements to the beat. The proposal specifies cortical brain pathways implicated in the origins of human beat-based dancing and leads to testable predictions and suggestions for future research.</p>","PeriodicalId":9031,"journal":{"name":"BMC Neuroscience","volume":null,"pages":null},"PeriodicalIF":2.4,"publicationDate":"2024-11-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11539772/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142589397","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Dance as mindful movement: a perspective from motor learning and predictive coding. 舞蹈是有意识的运动:从运动学习和预测编码的角度看问题。
IF 2.4 4区 医学
BMC Neuroscience Pub Date : 2024-11-06 DOI: 10.1186/s12868-024-00894-9
W Tecumseh Fitch, Rebecca Barnstaple
{"title":"Dance as mindful movement: a perspective from motor learning and predictive coding.","authors":"W Tecumseh Fitch, Rebecca Barnstaple","doi":"10.1186/s12868-024-00894-9","DOIUrl":"10.1186/s12868-024-00894-9","url":null,"abstract":"<p><p>Defining \"dance\" is challenging, because many distinct classes of human movement may be considered dance in a broad sense. Although the most obvious category is rhythmic dancing to a musical beat, other categories of expressive movement such as dance improvisation, pantomime, tai chi, or Japanese butoh suggest that a more inclusive conception of human dance is needed. Here we propose that a specific type of conscious awareness plays an overarching role in most forms of expressive movement and can be used to define dance (in the broad sense). We can briefly summarize this broader notion of dance as \"mindful movement.\" However, to make this conception explicit and testable, we need an empirically verifiable characterization of \"mindful movement.\" We propose such a characterization in terms of predictive coding and procedural learning theory: mindful movement involves a \"suspension\" of automatization. When first learning a new motor skill, we are highly conscious of our movements, and this is reflected in neural activation patterns. As skill increases, automatization and overlearning occurs, involving a progressive suppression of conscious awareness. Overlearned, habitual movement patterns become mostly unconscious, entering consciousness only when mistakes or surprising outcomes occur. In mindful movement, this automatization process is essentially inverted or suspended, reactivating previously unconscious details of movement in the conscious workspace, and crucially enabling a renewed aesthetic attention to such details. This wider perspective on dance has important implications for potential animal analogs of human dance and leads to multiple lines of experimental exploration.</p>","PeriodicalId":9031,"journal":{"name":"BMC Neuroscience","volume":null,"pages":null},"PeriodicalIF":2.4,"publicationDate":"2024-11-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11539728/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142589401","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Mobile brain imaging in butoh dancers: from rehearsals to public performance. 移动脑成像技术在武藤舞者身上的应用:从排练到公开表演。
IF 2.4 4区 医学
BMC Neuroscience Pub Date : 2024-11-06 DOI: 10.1186/s12868-024-00864-1
Constantina Theofanopoulou, Sadye Paez, Derek Huber, Eric Todd, Mauricio A Ramírez-Moreno, Badie Khaleghian, Alberto Muñoz Sánchez, Leah Barceló, Vangeline Gand, José L Contreras-Vidal
{"title":"Mobile brain imaging in butoh dancers: from rehearsals to public performance.","authors":"Constantina Theofanopoulou, Sadye Paez, Derek Huber, Eric Todd, Mauricio A Ramírez-Moreno, Badie Khaleghian, Alberto Muñoz Sánchez, Leah Barceló, Vangeline Gand, José L Contreras-Vidal","doi":"10.1186/s12868-024-00864-1","DOIUrl":"10.1186/s12868-024-00864-1","url":null,"abstract":"<p><strong>Background: </strong>Dissecting the neurobiology of dance would shed light on a complex, yet ubiquitous, form of human communication. In this experiment, we sought to study, via mobile electroencephalography (EEG), the brain activity of five experienced dancers while dancing butoh, a postmodern dance that originated in Japan.</p><p><strong>Results: </strong>We report the experimental design, methods, and practical execution of a highly interdisciplinary project that required the collaboration of dancers, engineers, neuroscientists, musicians, and multimedia artists, among others. We explain in detail how we technically validated all our EEG procedures (e.g., via impedance value monitoring) and minimized potential artifacts in our recordings (e.g., via electrooculography and inertial measurement units). We also describe the engineering details and hardware that enabled us to achieve synchronization between signals recorded at different sampling frequencies, along with a signal preprocessing and denoising pipeline that we used for data re-sampling and power line noise removal. As our experiment culminated in a live performance, where we generated a real-time visualization of the dancers' interbrain synchrony on a screen via an artistic brain-computer interface, we outline all the methodology (e.g., filtering, time-windows, equation) we used for online bispectrum estimations. Additionally, we provide access to all the raw EEG data and codes we used in our recordings. We, lastly, discuss how we envision that the data could be used to address several hypotheses, such as that of interbrain synchrony or the motor theory of vocal learning.</p><p><strong>Conclusions: </strong>Being, to our knowledge, the first study to report synchronous and simultaneous recording from five dancers, we expect that our findings will inform future art-science collaborations, as well as dance-movement therapies.</p>","PeriodicalId":9031,"journal":{"name":"BMC Neuroscience","volume":null,"pages":null},"PeriodicalIF":2.4,"publicationDate":"2024-11-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11539292/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142589328","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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