Journal of gastroenterology and hepatology research最新文献

{"title":"Cutoff Values for the Diagnosis if Sarcopenia in Pre-Liver Transplant Patients","authors":"T. Cabral, L. D. Rosa, C. Marroni, L. Galant, André Ferreira D'Avila, K. J. Berleze, J. F. Pereira, Danusa Rossi","doi":"10.17554/j.issn.2224-3992.2020.09.955","DOIUrl":"https://doi.org/10.17554/j.issn.2224-3992.2020.09.955","url":null,"abstract":"58 anos) e modelo para doenca hepatica final de 12 pontos; houve predominância de homens. A etiologia mais comum (60,4%) foi o virus da hepatite C. Os valores de corte foram MAMC ≤ 25,09 cm para a massa muscular, PT ≤ 93,4 Nm para a forca muscular e 6MWT ≤ 459 m para a funcao muscular. e as precisoes usadas para determinar a massa muscular, forca e funcao pelo MAMC, PT e 6MWT foram ≤ 25,09 cm e 77,9%, ≤ 93,4Nm e 72,72% e ≤ 459 me 75%, respectivamente.","PeriodicalId":90217,"journal":{"name":"Journal of gastroenterology and hepatology research","volume":"9 1","pages":"3270-3274"},"PeriodicalIF":0.0,"publicationDate":"2020-08-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45088836","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Investigation of Adiponectin, Leptin, Retinol Binding Protein-4 and Resistin Levels in Non-Diabetic and Non-Obese Patients With Non-Alcoholic Fatty Liver Disease","authors":"M. Ikizek, B. Kasapoglu, C. Türkay","doi":"10.17554/j.issn.2224-3992.2020.09.950","DOIUrl":"https://doi.org/10.17554/j.issn.2224-3992.2020.09.950","url":null,"abstract":"AIMS: This study aimed to investigate the levels of adiponectin, leptin, resistin and RBP-4 in the serum of NAFLD with non-obese and non-diabetic cases. METHODS: A total of 81 people aged between 25-72 were included in the study. 56 obese and non-diabetic NAFLD cases with fatty liver detected by ultrasonography (US) were compared with a control group of 25. Liver function tests and lipid profile analysis of all cases were performed, insulin resistance (HOMA –IR) was evaluated. Liver biopsy was performed in 18 patients. Biopsy patients were staged according to their groups. Serum values of adiponectin, leptin, resistin and RBP-4 were measured in all cases by ELISA method. RESULTS: Waist circumference, body mass index (BMI), alanine aminotransferase (ALT), aspartate aminotransferase (AST), gamma glutamyl transferase (GGT) and HOMA-IR values were higher in the NAFLD group and were considered statistically significant. Lipid profiles and adipokine levels were similar in both groups. There was no statistically significant difference between the groups. The mean values of adiponectin, resistin, leptin and RBP-4 were compared according to the biopsy stage, and the mean of leptin and resistin was not associated with the biopsy stage. A positive correlation was found between HOMA-IR and biopsy stage, and a negative correlation between averages of adiponectin and RBP-4. CONCLUSION: Unfortunately, not being overweight or fit doesn’t always lead to better health. Obese and non-diabetic individuals may also be at risk of fatty liver and steatohepatitis. Adipokines, which have roles in the pathogenesis of NAFLD, are increasingly important in detecting steohepatitis at an early stage. However, in our study, we did not find any significant differences between the groups in terms of adipokine profiles. For this purpose, studies with larger biopsy-based cases are needed.","PeriodicalId":90217,"journal":{"name":"Journal of gastroenterology and hepatology research","volume":"9 1","pages":"3275-3282"},"PeriodicalIF":0.0,"publicationDate":"2020-08-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45143558","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of Aerobic Physical Training in Non-Alcoholic Fat Hepatic Disease Aspects Related to Mitochondrial Biogenesis and Oxidative Stress: A Review","authors":"M. S. Fernandes, G. Santos, Isael João de Lima, Widemar Ferraz da Silva, S. S. Barbosa, Moara Rodrigues Costa, R. Santos, Tafnes Oliveira, I. Ribeiro, C. Calazans","doi":"10.17554/j.issn.2224-3992.2020.09.957","DOIUrl":"https://doi.org/10.17554/j.issn.2224-3992.2020.09.957","url":null,"abstract":"Non-alcoholic fatty liver disease (NAFLD) is one of the most common forms of liver disease, affecting about 20% to 30% of the adult population, being found more often in obese individuals (~ 90%). Among the main etiological factors are insulin resistance, mitochondrial dysfunction and oxidative stress. To date, no specific pharmacological treatment for NAFLD, so lifestyle modifications such as: reduction in body weight, diet and regular practice of aerobic physical exercise are effective, however it is not yet elucidated what the main impacts of physical exercise on NAFLD.","PeriodicalId":90217,"journal":{"name":"Journal of gastroenterology and hepatology research","volume":"9 1","pages":"3248-3252"},"PeriodicalIF":0.0,"publicationDate":"2020-08-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42271319","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Redo GPOEM for Refractory Gastroparesis: is it Feasible and Useful?","authors":"Baiwen Li, Lucie F. Calderon, Huimin Chen, Jennifer Xu, Q. Cai","doi":"10.17554/j.issn.2224-3992.2020.09.922","DOIUrl":"https://doi.org/10.17554/j.issn.2224-3992.2020.09.922","url":null,"abstract":"Per oral endoscopic pyloromyotomy (GPOEM or POP) is relatively new endoscopic therapy for gastroparesis. Studies indicate that the short term and long term efficacy are promsing. However, some patients may have recurrence with nausea and vomiting again certain time after the index GPOEM. We present cases here with the short term outcome of second GPOEM. The result is promising. This is the first report of the outcome of second GPOEM and more patients are needed for further study.","PeriodicalId":90217,"journal":{"name":"Journal of gastroenterology and hepatology research","volume":"9 1","pages":"3253-3254"},"PeriodicalIF":0.0,"publicationDate":"2020-08-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44944026","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact Of Pharmacy Ambulatory Care Services In Managing Patients With Diabetes In An Indigent Population Clinic: A","authors":"Justine Latif","doi":"10.24966/ghr-2566/100029","DOIUrl":"https://doi.org/10.24966/ghr-2566/100029","url":null,"abstract":"Purpose: The purpose of this study was to assess the benefit of pharmacist ambulatory care services in the management of patients with uncontrolled diabetes in an indigent population clinic. Methods: Patients with uncontrolled diabetes were referred to the pharmacist diabetes clinic (PDC) for diabetes management. The pharmacist collected, recorded, and assessed baseline and follow-up subjective and objective information during each appointment. Patients included for data collection were those referred to the PDC with uncontrolled diabetes despite previous health care provider management. Patients were excluded if another specialist was required to intervene in the care of the patient’s diabetes or if the patient did not follow-up at least once. The primary outcome was change in hemoglobin A1c (HgbA1c). The secondary outcomes were changes in fasting blood glucose (FBG), random blood glucose (RBG), number of patients experiencing hypoglycemic events, number of patients experiencing nocturia, the implementation of daily foot inspections, and medications prescribed prior to and after pharmacist intervention. Results: A paired t-test was conducted for objective lab values to assess the statistical significance of change prior to and after pharmacist intervention. Patients’ HgbA1c averaged 12.1% before and 9.8% after pharmacist intervention (95% CI, 0.656 to 3.884; p=0.0112). FBG levels averaged 198 mg/dL before and 147 mg/dL after pharmacist intervention (95% CI, -12.23 to 168.23; p=0.0841). RBG levels averaged 234 mg/dL before and 199 mg/dL after pharmacist intervention (95% CI, 2.58 to 202.14; p=0.0453). Four patients reported an average of 2 monthly hypoglycemic events before and 3 patients reported an average of 1 monthly hypoglycemic event after pharmacist intervention. Three patients before and 10 patients after pharmacist intervention checked their feet daily. Twelve patients before and 8 patients after pharmacist intervention experienced nocturia. Medication modifications decreased adverse events, intolerance, and hypoglycemia. Conclusion: Clinical pharmacist diabetes management provided a decrease in HgbA1c by 2.3%, FBG by 51 mg/dL, and RBG by 35 mg/ dL. Statistical significance was found with the change in HgbA1c and RBG values. Number of patients experiencing hypoglycemia and nocturia decreased after pharmacist intervention while the number of patients who checked their feet daily increased after pharmacist intervention. Medication regimens decreased adverse events, intolerance, and hypoglycemic events. Citation: Latif JM (2020) Impact of Pharmacy Ambulatory Care Services in Managing Patients with Diabetes in an Indigent Population Clinic: A Case Review Study. J Gastroenterol Hepatology Res 5: 029.","PeriodicalId":90217,"journal":{"name":"Journal of gastroenterology and hepatology research","volume":"32 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86111564","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Dietary regulation of people with wet constitution during COVID-19 epidemic","authors":"Zhuo Zhang, Wen-Bo Liu, Yan-Bin Lin","doi":"10.12032/GHR2020-06-016","DOIUrl":"https://doi.org/10.12032/GHR2020-06-016","url":null,"abstract":"","PeriodicalId":90217,"journal":{"name":"Journal of gastroenterology and hepatology research","volume":"73 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-06-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84215421","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Study on the potential mechanism of Pien Tze Huang Capsules against coronavirus disease 2019 based on network pharmacology","authors":"Hui Zhu, M. Xiao","doi":"10.12032/GHR2020-06-013","DOIUrl":"https://doi.org/10.12032/GHR2020-06-013","url":null,"abstract":"","PeriodicalId":90217,"journal":{"name":"Journal of gastroenterology and hepatology research","volume":"34 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-06-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76524580","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Liver regeneration microenvironment and heterogeneity of hepatocellular carcinoma","authors":"Xiang Gao, Hanmin Li","doi":"10.12032/GHR2020-06-015","DOIUrl":"https://doi.org/10.12032/GHR2020-06-015","url":null,"abstract":"","PeriodicalId":90217,"journal":{"name":"Journal of gastroenterology and hepatology research","volume":"9 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-06-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85993545","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Diagnosis and treatment of hyponatremia in patients with liver cirrhosis","authors":"Zhao-chun Chi","doi":"10.12032/GHR2020-06-012","DOIUrl":"https://doi.org/10.12032/GHR2020-06-012","url":null,"abstract":"","PeriodicalId":90217,"journal":{"name":"Journal of gastroenterology and hepatology research","volume":"81 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-06-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88291125","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Real world studies and their impact on the prevention and treatment of liver disease with traditional Chinese medicine","authors":"Jing-Hao Zhang, Chao Zheng, Xiao-Jun Zhu, Xin Zhang, Zhen-hua Zhou, Man Li, Yue-Qiu Gao, Xue-Hua Sun","doi":"10.12032/GHR2020-06-014","DOIUrl":"https://doi.org/10.12032/GHR2020-06-014","url":null,"abstract":"","PeriodicalId":90217,"journal":{"name":"Journal of gastroenterology and hepatology research","volume":"32 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-06-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81611348","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}