Blood Pressure最新文献

{"title":"Reconsidering the role of acupuncture in circadian blood pressure regulation: reflections and future directions.","authors":"Jinpeng Wen, Zilin Zhao, Hejia Wan","doi":"10.1080/08037051.2026.2613530","DOIUrl":"10.1080/08037051.2026.2613530","url":null,"abstract":"","PeriodicalId":9000,"journal":{"name":"Blood Pressure","volume":" ","pages":"2613530"},"PeriodicalIF":2.3,"publicationDate":"2026-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145931476","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Characteristics of post-exercise responders versus non-responders following aerobic or isometric exercise in physically inactive adults of African and South Asian descent with high-normal blood pressure or grade I hypertension.","authors":"Marina Bersaoui, Se-Sergio Baldew, Kwame van der Hilst, Jerry Toelsie, Veronique Cornelissen","doi":"10.1080/08037051.2026.2717787","DOIUrl":"10.1080/08037051.2026.2717787","url":null,"abstract":"<p><strong>Objective: </strong>To investigate interindividual variability in post-exercise hypotension (PEH) and to characterise cardiovascular and autonomic differences between responders and non-responders following aerobic and isometric exercise in adults of African and South Asian descent with elevated blood pressure (BP).</p><p><strong>Methods: </strong>Physically inactive adults of African and South Asian descent living in Suriname (18-65 years) with high-normal BP or grade I hypertension participated in a randomised controlled crossover trial. In this randomised cross-over trial, 47 adults (50.1 ± 10.8 years; 38% male) with high-normal blood pressure or grade I hypertension completed three conditions: aerobic exercise (30 min at 40-60% heart rate reserve), isometric handgrip exercise, and a non-exercise control. Ambulatory BP was assessed over 24 h. PEH was defined as the net effect: (post-exercise - pre-exercise) - (post-control - pre-control). Participants were classified as responders if daytime BP decreased ≥5 mmHg. Arterial stiffness, cardiac, and autonomic parameters were assessed.</p><p><strong>Results: </strong>Following aerobic exercise, 46% of participants were classified as systolic responders compared with 28% after isometric exercise. No baseline differences were observed in demographic or clinical characteristics between responders and non-responders, suggesting that PEH variability may reflect underlying physiological rather than clinical differences. Aerobic responders demonstrated greater reductions in aortic augmentation index (-19.4% vs. -10.9%, <i>p</i> = 0.05), larger increases in stroke volume (+8.1 vs. -5.3 mL, <i>p</i> = 0.05) and cardiac output (+1.54 ± 1.89 vs. +0.58 ± 1.60 L/min, <i>p</i> = 0.009), and more favourable autonomic recovery. Among all variables, only the change in cardiac output was associated with PEH magnitude (<i>r</i> = -0.46, <i>p</i> = 0.006). No consistent physiological differences were observed following isometric exercise.</p><p><strong>Conclusion: </strong>PEH following aerobic exercise is characterised by a distinct responder phenotype associated with greater reductions in aortic augmentation index and favourable cardiac adaptations. These findings highlight substantial interindividual variability in BP responses and support the need for individualised exercise strategies in hypertension management.</p>","PeriodicalId":9000,"journal":{"name":"Blood Pressure","volume":" ","pages":"2717787"},"PeriodicalIF":2.3,"publicationDate":"2026-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148863447","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Hypertension epidemiology and primary care indicators in Portugal: a contemporary nationwide analysis.","authors":"Rosa de Pinho, Luís Nogueira-Silva, José Lima Nogueira, Francisca Abecasis, Vasco Varela, Cláudia de Oliveira Pinho, Ana Catarina Gomes, Catarina Venda Grilo, Daniel Ramos, Daniela Mariana Zagalo, Filipa Bernardo, Guilherme Pessoa-Amorim, João Couceiro, Marisa Pardal, Rita Canhoto, Rudolfo Francisco, Patrícia Branco, Fernando Pinto, Fernando Martos Gonçalves, Heloísa Ribeiro","doi":"10.1080/08037051.2026.2729494","DOIUrl":"https://doi.org/10.1080/08037051.2026.2729494","url":null,"abstract":"<p><strong>Background: </strong>Hypertension remains a leading contributor to cardiovascular mortality worldwide. However, integrated surveillance frameworks linking epidemiological burden, healthcare performance, and clinical outcomes remain limited. This study aimed to characterise hypertension epidemiology and management in Portuguese primary health care using real-world evidence from publicly-available indicators.</p><p><strong>Methods: </strong>A retrospective ecological (aggregated group-level) study was conducted, using the five Portuguese mainland administrative health regions and the country as the units of analysis, with data obtained from Portuguese primary health care information systems from 2021-2025. Temporal and regional trends in hypertension prevalence and incidence, blood pressure (BP) monitoring and control, cardiovascular risk assessment, therapeutic review, prescribing patterns, and composite management indicators were assessed. A multidisciplinary expert panel provided structured clinical appraisal of indicator relevance and interpretability.</p><p><strong>Results: </strong>Hypertension prevalence and incidence increased nationally, with regional heterogeneity. The Norte region showed higher performance across monitoring and control indicators, whereas Algarve and Alentejo exhibited generally poorer results. BP monitoring and control improved across all regions, with the proportion of hypertensive adults aged 18-64 years, with BP <140/90 mmHg increasing from 29.3% in 2021 to 65.0% in 2025. Composite management indicators improved, but the degree of improvement varied between different index versions. Medication costs generally increased up to 2024 but decreased afterwards, while prescription indicators remained stable.</p><p><strong>Conclusion: </strong>Hypertension management indicators in Portuguese primary care improved substantially between 2021 and 2025; however, regional disparities and methodological limitations remain. Current monitoring frameworks provide valuable real-world insights but incompletely capture clinically meaningful outcomes, supporting the need for more outcome-directed systems.</p>","PeriodicalId":9000,"journal":{"name":"Blood Pressure","volume":"35 1","pages":"2729494"},"PeriodicalIF":2.3,"publicationDate":"2026-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149102855","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Letter to editor: flexibility of nonparametric regression for improved model fit in blood pressure variability between radial artery and finger.","authors":"Andrea Tri Rian Dani, I Nyoman Budiantara, Nur Chamidah, Kadek Adi Surya Negara","doi":"10.1080/08037051.2026.2742836","DOIUrl":"https://doi.org/10.1080/08037051.2026.2742836","url":null,"abstract":"","PeriodicalId":9000,"journal":{"name":"Blood Pressure","volume":"35 1","pages":"2742836"},"PeriodicalIF":2.3,"publicationDate":"2026-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149103607","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The role of epigenetics in hypertension of children and adolescents: a systematic review.","authors":"Lilik Sukesi, Yunia Sribudiani, Steven Yulius Usman, Eric Ricardo Yonatan, Ahmedz Widiasta, Noormarina Indraswari, Ria Bandiara, Nanny Nm Soetedjo","doi":"10.1080/08037051.2025.2598105","DOIUrl":"10.1080/08037051.2025.2598105","url":null,"abstract":"<p><strong>Aim: </strong>This systematic review study aimed to discuss about the possibility role of epigenetic in HTN of children and adolescent.</p><p><strong>Material and methods: </strong>This evidence-based research is implemented within the scope of the Preferred Reporting Item for Systematic Review and Meta-analysis (PRISMA) 2020. The data were analyzed qualitatively to assess the risk of bias, with the New Ottawa Scale (NOS) and Agency for Health Research and Quality (AHRQ) criteria as the thresholds. Our research highlights in particular showed that there is a role for epigenetics in HTN in children and adolescents.</p><p><strong>Conclusion: </strong>Fourteen journals were included to be qualitatively assessed. Eleven journals (78.5%) stated that there was a correlation between epigenetic and BP in children and adolescents, however each study examined different genes or loci. In summary, epigenetic modifications of various single nucleotide polymorphisms (SNPs) and other genes were associated with higher systolic and diastolic BP in children and adolescents.</p>","PeriodicalId":9000,"journal":{"name":"Blood Pressure","volume":" ","pages":"2598105"},"PeriodicalIF":2.3,"publicationDate":"2026-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145647301","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association of intraoperative mean arterial pressure with postoperative organ dysfunction in elderly hypertensive patients: a retrospective cohort study.","authors":"Li Qu, Yankai Ma, Xuan Zhao, Qianqian Zhu, Xueying Chen, Jing Jin, Guiping Xu","doi":"10.1080/08037051.2025.2607166","DOIUrl":"10.1080/08037051.2025.2607166","url":null,"abstract":"<p><strong>Background: </strong>Maintaining intraoperative mean arterial pressure (MAP) is crucial for surgical safety in elderly hypertensive patients, but the optimal target remains unclear. This study evaluated the association between different intraoperative MAP ranges and postoperative stress responses and organ function.</p><p><strong>Methods: </strong>We conducted a single-center retrospective cohort study of 368 elderly hypertensive patients undergoing surgery under general anaesthesia. Patients were categorised into three groups based on actual intraoperative MAP: 65-75 mmHg, 75-85 mmHg, and 85-95 mmHg. Postoperative stress markers (cortisol, C-reactive protein [CRP]) and organ function markers (cardiac, renal, neurologic) were analysed using routine perioperative data.</p><p><strong>Results: </strong>Patients in the low MAP group (65-75 mmHg) showed the highest postoperative cortisol and CRP levels, indicating stronger stress responses, and were more likely to experience myocardial and renal impairment. The high MAP group (85-95 mmHg) had a slightly increased cardiac load. The moderate MAP group (75-85 mmHg) demonstrated a balanced profile, with lower stress levels and better preservation of cardiac and renal function. Neurologic injury markers (NSE, S100β) and the incidence of postoperative delirium showed no statistically significant differences among groups, though trends towards higher values were observed in the low MAP group.</p><p><strong>Conclusion: </strong>Maintaining intraoperative MAP within 75-85 mmHg appears to reduce postoperative stress and preserve cardiac and renal function in elderly hypertensive patients. Neurologic outcomes did not differ significantly, but avoiding excessively low MAP may help minimise potential neurological risk.</p>","PeriodicalId":9000,"journal":{"name":"Blood Pressure","volume":" ","pages":"2607166"},"PeriodicalIF":2.3,"publicationDate":"2026-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145793142","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association of the angiotensin II type 1 receptor A1166C polymorphism with essential hypertension in the Chinese population: a meta-analysis with ethnic and geographic subgroup analyses.","authors":"Jun Gu, Li Shi, Weidong Ren, Zhengrong Xu, Wenjuan Deng, Limei Hu, Huiying Liu, Zhiying Zhang, Gaijun Ning, Yu Cai","doi":"10.1080/08037051.2026.2676370","DOIUrl":"10.1080/08037051.2026.2676370","url":null,"abstract":"<p><strong>Purpose: </strong>This study aims to explore the association between the angiotensin II type 1 receptor (AT1R) A1166C gene polymorphism and susceptibility to essential hypertension (EH) within the Chinese population.</p><p><strong>Materials and methods: </strong>Relevant literature published domestically and internationally was systematically retrieved from database inception to 31 December 2024. A total of 17 eligible studies involving 9,213 patients with EH and 4,494 healthy controls were included. Meta-analysis, subgroup analysis (by ethnicity and region), sensitivity analysis and publication bias assessment were performed.</p><p><strong>Results: </strong>Meta-analysis showed that the <i>AC</i>/<i>CC</i> genotype (odds ratio [OR] = 1.34, 95% confidence interval [CI]: 1.07-1.69, <i>p</i> = 0.01) and <i>C</i> allele (OR = 1.44, 95% CI: 1.14-1.82, <i>p</i> = 0.002) were modestly associated with an increased EH risk. Subgroup analysis revealed significant associations in the Han (<i>AC</i>/<i>CC</i>: OR = 1.56; <i>C</i> allele: OR = 1.58) and Yi (<i>AC</i>/<i>CC</i>: OR = 1.80; <i>C</i> allele: OR = 1.84) populations, as well as a significant association between the <i>C</i> allele and EH in northern/northwestern regions (OR = 1.37, <i>p</i> = 0.04). However, these subgroup findings should be interpreted cautiously. Funnel plots indicated low publication bias.</p><p><strong>Conclusion: </strong>The AT1R A1166C polymorphism may modestly contribute to EH susceptibility in the Chinese population, with ethnic and regional factors partly influencing this association. Large-scale prospective studies with more balanced subgroup representations and standardised blood pressure assessment methods are needed to validate these findings.</p>","PeriodicalId":9000,"journal":{"name":"Blood Pressure","volume":" ","pages":"2676370"},"PeriodicalIF":2.3,"publicationDate":"2026-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147970160","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"J‑shaped link of stress hyperglycaemia ratio with in-hospital and 1-year mortality in hypertension patients: based on the MIMIC-IV database.","authors":"Dan Zhao, Fan Wang, Yanzhi Ding, Xinshun Gu","doi":"10.1080/08037051.2026.2709810","DOIUrl":"10.1080/08037051.2026.2709810","url":null,"abstract":"<p><strong>Background: </strong>Stress hyperglycaemia ratio (SHR) is notably linked with unfavourable prognoses. Nevertheless, this correlation in hypertension is elusive. This paper uncovered a link of SHR with mortality in hypertension populations.</p><p><strong>Methods: </strong>Hypertension patients in ICUs were enrolled from the MIMIC database. The outcomes assessed encompassed in-hospital and 1-year death. SHR was categorised into four groups, and its connection with mortality was assessed using Cox regression analysis. The restricted cubic spline method was leveraged to appraise the non-linear link of SHR with mortality.</p><p><strong>Results: </strong>2088 patients were enrolled, with 8.67% of in-hospital and 19.92% of 1-year mortality. As a continuous variable, each one-unit enhancement in SHR was connected with an elevation in in-hospital (HR, 1.93 [95% CI: 1.50-2.47]) and 1-year deaths (HR, 1.66 [95% CI: 1.37-2.01]); SHR as a categorical variable, the Q4 group exhibited enhanced in-hospital (HR, 3.29 [95% CI: 1.89-5.74]) and 1-year death (HR, 1.74 [95% CI: 1.29-2.35]). There was a J-shaped connection of SHR with in-hospital and 1-year deaths.</p><p><strong>Conclusion: </strong>SHR index can predict in-hospital and 1-year deaths in individuals with critical hypertension.</p>","PeriodicalId":9000,"journal":{"name":"Blood Pressure","volume":" ","pages":"2709810"},"PeriodicalIF":2.3,"publicationDate":"2026-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148787974","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Blood pressure variability between radial artery and finger is influenced by haemodynamic factors, age and insulin resistance.","authors":"Manoj Kumar Choudhary, Tuomas Saarinen, Matti Oivo, Johanna Tietäväinen, Antti Tikkakoski, Jukka T Mustonen, Ilkka H Pörsti, Jenni K Koskela","doi":"10.1080/08037051.2026.2703350","DOIUrl":"10.1080/08037051.2026.2703350","url":null,"abstract":"<p><strong>Background: </strong>In clinical practice, blood pressure (BP) is typically assessed using brachial measurements, whereas finger plethysmography is widely used in vascular physiology research. However, agreement between BP levels at the finger and more proximal sites is not straightforward because of interindividual differences in BP gradients along the arterial tree.</p><p><strong>Methods: </strong>We investigated factors associated with the mean arterial pressure (MAP) difference between non-invasive radial artery and finger measurements in 574 normotensive and hypertensive individuals without cardiovascular disease, diabetes or antihypertensive medication. Recordings included pulse wave analysis from radial BP, plethysmographic finger BP and whole-body impedance cardiography. Radial BP signals were calibrated using oscillometric contralateral brachial artery measurements.</p><p><strong>Results: </strong>Simultaneous mean radial and finger BP (systolic/diastolic) were 131/75 and 122/69 mmHg, respectively (<i>p</i> < .001). When examined in quartiles of the radial-finger BP gradient, the average MAP difference was -7, 4, 10 and 20 mmHg, respectively. In linear regression analysis (enter method), a greater MAP difference was significantly associated with higher radial MAP (<i>p</i> < .001), age (<i>p</i> = .001) and stroke index (<i>p</i> = .015); and with lower pulse wave velocity (<i>p</i> < .001), pulse pressure amplification (<i>p</i> = .002) and insulin sensitivity check index (<i>p</i> = .022).</p><p><strong>Conclusions: </strong>High MAP is a major factor contributing to greater BP difference between the radial and finger sites. However, the difference is also more pronounced in the presence of lower large artery stiffness, lower pulse pressure amplification, and higher stroke index, older age and greater insulin resistance.</p>","PeriodicalId":9000,"journal":{"name":"Blood Pressure","volume":" ","pages":"2703350"},"PeriodicalIF":2.3,"publicationDate":"2026-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148762244","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Positive life orientation and blood pressure across generations: treatment and measurement require cautious interpretation.","authors":"Ahmad Abdullah Zawawi, Muhammad Farid Ilhamuddin, Muhammad Wahyu Ariyanto, M S Haq","doi":"10.1080/08037051.2026.2726595","DOIUrl":"10.1080/08037051.2026.2726595","url":null,"abstract":"","PeriodicalId":9000,"journal":{"name":"Blood Pressure","volume":" ","pages":"2726595"},"PeriodicalIF":2.3,"publicationDate":"2026-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148839076","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}