Blood Pressure最新文献_第4页

Correction. 更正。

IF 1.8 4区医学

Blood Pressure Pub Date : 2024-12-01 Epub Date: 2024-05-15 DOI: 10.1080/08037051.2024.2351688

引用次数: 0

Discovering a novel genetic variant in 11 family members who had isolated pheochromocytoma linked to von Hippel-Lindau (VHL) syndrome, aligning with the type 2c phenotype. 在 11 个患有与 von Hippel-Lindau (VHL) 综合征相关的孤立性嗜铬细胞瘤的家族成员中发现一种新型基因变异，与 2c 型表型一致。

IF 1.8 4区医学

Blood Pressure Pub Date : 2024-12-01 Epub Date: 2024-06-02 DOI: 10.1080/08037051.2024.2355268

Hussein Alhawari, Zaina Obeidat, Lina Wahbeh, Ayman Mismar, Nedal Younis, Hanan Jafar, Munther Momani, Nedal Alsabatin, Abdalla Awidi, Hussam Alhawari

{"title":"Discovering a novel genetic variant in 11 family members who had isolated pheochromocytoma linked to von Hippel-Lindau (VHL) syndrome, aligning with the type 2c phenotype.","authors":"Hussein Alhawari, Zaina Obeidat, Lina Wahbeh, Ayman Mismar, Nedal Younis, Hanan Jafar, Munther Momani, Nedal Alsabatin, Abdalla Awidi, Hussam Alhawari","doi":"10.1080/08037051.2024.2355268","DOIUrl":"https://doi.org/10.1080/08037051.2024.2355268","url":null,"abstract":"Introduction: Von Hippel-Lindau disease (e.g. VHL) is an autosomal dominant multi-organ cancer syndrome caused by a mutation in the VHL tumour suppressor gene. In this study, we introduce a novel genetic variant found in 11 family members diagnosed initially with isolated Pheochromocytoma. Subsequent findings revealed its association with VHL syndrome and corresponds to the Type 2 C phenotype.Methods: The VHL gene was amplified through the utilisation of the polymerase chain reaction (PCR). PCR fragments were sequenced using bidirectional Sanger sequencing, using BigDye™ Terminator v3.1 Cycle Sequencing Kit, running on the 3500 genetic analyser. Results were assembled and analysed Using Software SeqA and chromas pro.Results: A heterozygous in-frame duplication of three nucleotides, specifically ATG, c.377_379dup; p.Asp126dup in exon 2, was identified in all the patients tested within the pedigree.Conclusion: In this study, we disclose the identification of a novel genetic variant in a Jordanian family, affecting eleven family members with pheochromocytoma associated with VHL disease. This finding underscores the importance of screening family members and contemplating genetic testing for individuals newly diagnosed with pheochromocytoma and could enhance our comprehension of the potential adverse consequences associated with VHL germline mutations.","PeriodicalId":9000,"journal":{"name":"Blood Pressure","volume":"33 1","pages":"2355268"},"PeriodicalIF":1.8,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141199288","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Elderly men are underscreened for primary aldosteronism even in Hypertension Excellence Centre. 即使在高血压卓越中心，老年男性原发性醛固酮增多症的筛查也不足。

IF 1.8 4区医学

Blood Pressure Pub Date : 2024-12-01 Epub Date: 2024-07-22 DOI: 10.1080/08037051.2024.2378878

Avital Angel Korman, Vladimir Rapoport, Hadassa Rimonie Seged German, Naomi Nakash Niddam, Zeev Katzir, Michael Hausmann, Adi Leiba

{"title":"Elderly men are underscreened for primary aldosteronism even in Hypertension Excellence Centre.","authors":"Avital Angel Korman, Vladimir Rapoport, Hadassa Rimonie Seged German, Naomi Nakash Niddam, Zeev Katzir, Michael Hausmann, Adi Leiba","doi":"10.1080/08037051.2024.2378878","DOIUrl":"https://doi.org/10.1080/08037051.2024.2378878","url":null,"abstract":"Purpose The Endocrine Society (ES) guidelines recommend screening for primary aldosteronism (PA) in high risk hypertensive patients presenting with at least one of seven criteria (resistant HTN, hypokalaemia, adrenal nodule, etc.) Although guidelines are clear and screening is simple, compliance rates among clinicians are extremely low. This results in underdiagnosis of early disease, leading to cadiovasculaer complications and the extra-burden of advanced chronic kidney disease. We aimed to evaluate the screening rates in our Nephrology and Hypertension clinics, as an example of a dedicated Hypertension Excellence Centre. Materials and methods Data on adult hypertensive patients was retrieved from January 2018 to December 2020. Included in the study were hypertensive patients who had at least one of the ES criteria for PA screening. Of all suitable patients, we compared those who were screened for PA to patients who were not screened. Univariate and multivariate cox regression analyses were used for comparison between groups. Results Of 661 patients with HTN, 218 patients (33%) met the ES guidelines for PA screening. Forty-six of them (21.1%) were referred for screening. Advanced age and male gender were associated with lower screening referral rates. Odds ratio for age was 0.945 for every year (95% CI 0.915 - 0.975). There was a trend towards decreased referral rate in advanced kidney disease. Conclusions A 21% screening rate, suggests that many cases of PA are likely missed, more often in older patients. We therefore advocate for PA screening of all hypertensive patients, especially elderly patients with CKD, in whom clinicians' awareness is low but the absolute risk is high.","PeriodicalId":9000,"journal":{"name":"Blood Pressure","volume":"33 1","pages":"2378878"},"PeriodicalIF":1.8,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141747417","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Significance of blood pressure variability in normotensive individuals as a risk factor of developing hypertension. 血压正常者的血压变化作为高血压发病风险因素的意义。

IF 1.8 4区医学

Blood Pressure Pub Date : 2024-12-01 Epub Date: 2024-03-11 DOI: 10.1080/08037051.2024.2323967

Hiroyuki Takase, Tomonori Sugiura, Sumiyo Yamashita, Naomi Kawakatsu, Kazusa Hayashi, Fumihiko Kin, Takeru Isogaki, Yasuaki Dohi

{"title":"Significance of blood pressure variability in normotensive individuals as a risk factor of developing hypertension.","authors":"Hiroyuki Takase, Tomonori Sugiura, Sumiyo Yamashita, Naomi Kawakatsu, Kazusa Hayashi, Fumihiko Kin, Takeru Isogaki, Yasuaki Dohi","doi":"10.1080/08037051.2024.2323967","DOIUrl":"10.1080/08037051.2024.2323967","url":null,"abstract":"Purpose: Visit-to-visit blood pressure variability is a strong predictor of the incidence of cardiovascular events and target organ damage due to hypertension. The present study investigated whether year-to-year blood pressure variability predicts the risk of hypertension in the Japanese general population.Materials and methods: This study analysed 2806 normotensive individuals who participated in our physical check-up program for five years in a row from 2008 to 2013. The average, standard deviation, coefficient of variation, average real variability, and highest value of systolic blood pressure in the five consecutive visits were determined and used as baseline data. The participants were followed up for the next 6 years with the development of 'high blood pressure', an average blood pressure level of ≥140/90 mmHg or the use of antihypertensive medications, as the endpoint.Result: During follow-up, 'high blood pressure' developed in 389 participants (13.9%, 29.5 per 1 000 person-years). The incidence increased across the quartiles of standard deviation and average real variability, while the average and highest systolic blood pressure had the most prominent impact on the development of 'high blood pressure'. Multivariate logistic regression analysis adjusted for possible risk factors indicated that the average, standard deviation, average real variability, and highest blood pressure, but not the coefficient of variation of systolic blood pressure, were significant predictors of 'high blood pressure'.Conclusion: Increased year-to-year blood pressure variability predicts the risk of hypertension in the general normotensive population. The highest blood pressure in the preceding years may also be a strong predictor of the risk of hypertension.","PeriodicalId":9000,"journal":{"name":"Blood Pressure","volume":"33 1","pages":"2323967"},"PeriodicalIF":1.8,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140093431","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Echocardiographic findings following renal sympathetic denervation for treatment resistant hypertension, the ReShape CV-risk study. 肾交感神经去神经化治疗耐药高血压后的超声心动图结果，ReShape CV 风险研究。

IF 1.8 4区医学

Blood Pressure Pub Date : 2024-12-01 Epub Date: 2024-03-12 DOI: 10.1080/08037051.2024.2326298

Anna Subbotina, Eystein Skjølsvik, Marit Dahl Solbu, Atena Miroslawska, Terje Steigen

{"title":"Echocardiographic findings following renal sympathetic denervation for treatment resistant hypertension, the ReShape CV-risk study.","authors":"Anna Subbotina, Eystein Skjølsvik, Marit Dahl Solbu, Atena Miroslawska, Terje Steigen","doi":"10.1080/08037051.2024.2326298","DOIUrl":"10.1080/08037051.2024.2326298","url":null,"abstract":"Objective: The aim of this study was to describe and compare echocardiographic findings before renal sympathetic denervation (RDN) and 6 and 24 months after the procedure.Materials and methods: Patients with treatment resistant hypertension (TRH) were included in this non-randomised intervention study. RDN was performed by a single experienced operator using the Symplicity Catheter System. Echocardiographic measurements were performed at baseline, and after 6 and 24 months.Results: The cohort consisted of 21 patients with TRH, with a mean systolic office blood pressure (BP) of 163 mmHg and mean diastolic BP 109 mmHg. Mixed model analysis showed no significant change in left ventricular (LV) mass index (LVMI) or left atrium volume index (LAVI) after the RDN procedure. Higher LVMI at baseline was significantly associated with greater reduction in LVMI (p < 0.001). Relative wall thickness (RWT) increased over time (0.48 mm after two years) regardless of change in BP. There was a small but significant reduction in LV end-diastolic (LVIDd) and end-systolic (LVIDs) diameters after RDN, with a mean reduction of 2.6 and 2.4 mm, respectively, after two years. Progression to concentric hypertrophy was observed only in in patients who did not achieve normal BP values, despite BP reduction after RDN.Conclusion: There was no reduction of LV mass after RDN. We found a small statistically significant reduction in LVIDd and LVIDs, which together with increase in RWT can indicate progression towards concentric hypertrophy. BP reduction after RDN on its own does not reverse concentric remodelling if target BP is not achieved.","PeriodicalId":9000,"journal":{"name":"Blood Pressure","volume":"33 1","pages":"2326298"},"PeriodicalIF":1.8,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140101025","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Highlights of the 2023 European Society of Hypertension Guidelines: what has changed in the management of hypertension in patients with cardiac diseases? 2023 年欧洲高血压学会指南要点：心脏病患者的高血压管理有何变化？

IF 1.8 4区医学

Blood Pressure Pub Date : 2024-12-01 Epub Date: 2024-03-31 DOI: 10.1080/08037051.2024.2329571

Sverre E Kjeldsen, Brent M Egan, Michel Burnier, Krzysztof Narkiewicz, Reinhold Kreutz, Giuseppe Mancia

引用次数: 0

Sex disparities in hypertension prevalence, blood pressure trajectories and the effects of anti-hypertensive treatment. 高血压发病率、血压轨迹和抗高血压治疗效果的性别差异。

IF 1.8 4区医学

Blood Pressure Pub Date : 2024-12-01 Epub Date: 2024-07-02 DOI: 10.1080/08037051.2024.2365705

Esther M C Vriend, Henrike Galenkamp, Irene G M van Valkengoed, Bert-Jan H van den Born

{"title":"Sex disparities in hypertension prevalence, blood pressure trajectories and the effects of anti-hypertensive treatment.","authors":"Esther M C Vriend, Henrike Galenkamp, Irene G M van Valkengoed, Bert-Jan H van den Born","doi":"10.1080/08037051.2024.2365705","DOIUrl":"https://doi.org/10.1080/08037051.2024.2365705","url":null,"abstract":"Introduction: Sex differences in blood pressure (BP), hypertension and hypertension mediated cardiovascular complications have become an increasingly important focus of attention. This narrative review gives an overview of current studies on this topic, with the aim to provide a deeper understanding of the sex-based disparities in hypertension with essential insights for refining prevention and management strategies for both men and women.Methods and results: We searched Medline, Embase and the Cochrane libray on sex differences in BP-trajectories and hypertension prevalence. In the past decade various population-based studies have revealed substantial sex-disparities in BP-trajectories throughout life with women having a larger increase in hypertension prevalence after 30 years of age and a stronger association between BP and cardiovascular disease (CVD). In general, the effects of antihypertensive treatment appear to be consistent across sexes in different populations, although there remains uncertainty about differences in the efficacy of BP lowering drugs below 55 years of age.Conclusion: The current uniform approach to the diagnosis and management of hypertension in both sexes neglects the distinctions in hypertension, while the differences underscore the need for sex-specific recommendations, particularly for younger individuals. A major limitation hampering insights into sex differences in BP-related outcomes is the lack of sex-stratified analyses or an adequate representation of women. Additional large-scale, longitudinal studies are imperative.","PeriodicalId":9000,"journal":{"name":"Blood Pressure","volume":"33 1","pages":"2365705"},"PeriodicalIF":1.8,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141490766","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The association between serum folate and elderly diastolic hypertension: results from the NHANES (2007-2018). 血清叶酸与老年舒张性高血压之间的关系：NHANES（2007-2018 年）的结果。

IF 1.8 4区医学

Blood Pressure Pub Date : 2024-12-01 Epub Date: 2024-07-17 DOI: 10.1080/08037051.2024.2380002

Hong Xie, Xiao-Feng Fan, Wen-Huan Shuai, Gui-You Zhong

{"title":"The association between serum folate and elderly diastolic hypertension: results from the NHANES (2007-2018).","authors":"Hong Xie, Xiao-Feng Fan, Wen-Huan Shuai, Gui-You Zhong","doi":"10.1080/08037051.2024.2380002","DOIUrl":"https://doi.org/10.1080/08037051.2024.2380002","url":null,"abstract":"Aim: To explore the association between serum folate concentration and the prevalence of elderly diastolic hypertension. This study aims to identify potential relationships that could inform further research into the mechanisms underlying hypertension management.Methods: Data from six NHANES cycles (2007-2008, 2009-2010, 2011-2012, 2013-2014, 2015-2016, and 2017-2018) were analysed for individuals aged over 60. Weighted logistic regression estimated odds ratios (ORs) and 95% confidence intervals (CIs). Subgroup and restricted cubic spline (RCS) regression explored the serum folate concentration and elderly diastolic hypertension relationship.Results: This study included 9,419 participants (4,734 females and 4,685 males) with a mean age of 70.0 ± 7.0 years. Among them, 360 were diagnosed with diastolic hypertension. In the fully adjusted model, there was a negative correlation between serum folate concentration and the prevalence of diastolic hypertension (OR 0.65; 95% CI: 0.52-0.82). When serum folate concentration levels were divided into quartiles (in μg/dL), the ORs for diastolic hypertension corresponding to Q2 (1.29-1.98), Q3 (1.99-3.08), and Q4 (3.09-5.56) levels compared to Q1 (0.18-1.28) were 1.41 (95% CI: 0.60-3.33), 0.48(95% CI: 0.20-1.16), and 0.35 (95% CI: 0.16-0.74), respectively, with a P for trend <.05. Restricted cubic spline plots showed a negative correlation between serum folate concentration and the prevalence of diastolic hypertension (non-linearity: p = .495). Subgroup analysis indicated that the negative correlation between serum folate concentration and the prevalence of diastolic hypertension was more significant in female participants (interaction p = .009).Conclusion: Higher serum folate concentration is associated with a lower prevalence of diastolic hypertension in the elderly.","PeriodicalId":9000,"journal":{"name":"Blood Pressure","volume":"33 1","pages":"2380002"},"PeriodicalIF":1.8,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141632592","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Masked phenomenon: renal and cardiovascular complications; review and updates. 掩蔽现象：肾脏和心血管并发症；回顾与更新。

IF 1.8 4区医学

Blood Pressure Pub Date : 2024-12-01 Epub Date: 2024-07-26 DOI: 10.1080/08037051.2024.2383234

Elmukhtar Habas, Almehdi Errayes, Eshrak Habas, Gamal Alfitori, Ala Habas, Kalifa Farfar, Amnna Rayani, Aml Habas, Abdel-Nasser Elzouki

{"title":"Masked phenomenon: renal and cardiovascular complications; review and updates.","authors":"Elmukhtar Habas, Almehdi Errayes, Eshrak Habas, Gamal Alfitori, Ala Habas, Kalifa Farfar, Amnna Rayani, Aml Habas, Abdel-Nasser Elzouki","doi":"10.1080/08037051.2024.2383234","DOIUrl":"https://doi.org/10.1080/08037051.2024.2383234","url":null,"abstract":"Background: In the in-clinic blood pressure (BP) recording setting, a sizable number of individuals with normal BP and approximately 30% of patients with chronic renal disease (CKD) exhibit elevated outpatient BP records. These individuals are known as masked hypertension (MHTN), and when they are on antihypertensive medications, but their BP is not controlled, they are called masked uncontrolled hypertension (MUHTN). The masked phenomenon (MP) (MHTN and MUHTN) increases susceptibility to end-organ damage (a two-fold greater risk for cardiovascular events and kidney dysfunction). The potential extension of the observed benefits of MP therapy, including a reduction in end-organ damage, remains questionable.Aim and methods: This review aims to study the diagnostic methodology, epidemiology, pathophysiology, and significance of MP management in end-organs, especially the kidneys, cardiovascular system, and outcomes. To achieve the purposes of this non-systematic comprehensive review, PubMed, Google, and Google Scholar were searched using keywords, texts, and phrases such as masked phenomenon, CKD and HTN, HTN types, HTN definition, CKD progression, masked HTN, MHTN, masked uncontrolled HTN, CKD onset, and cardiovascular system and MHTN. We restricted the search process to the last ten years to search for the latest updates.Conclusion: MHTN is a variant of HTN that can be missed if medical professionals are unaware of it. Early detection by ambulatory or home BP recording in susceptible individuals reduces end-organ damage and progresses to sustained HTN. Adherence to the available recommendations when dealing with masked phenomena is justifiable; however, further studies and recommendation updates are required.","PeriodicalId":9000,"journal":{"name":"Blood Pressure","volume":"33 1","pages":"2383234"},"PeriodicalIF":1.8,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141756932","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Orthostatic hypertension: the forgotten phenotype. 直立性高血压：被遗忘的表型。

IF 1.8 4区医学

Blood Pressure Pub Date : 2024-12-01 Epub Date: 2024-11-25 DOI: 10.1080/08037051.2024.2431565

Paolo Palatini, Sverre E Kjeldsen, Michel Burnier

引用次数: 0