Blood Pressure最新文献

{"title":"Clarifying the definition of 'elevated' blood pressure in the 2024 European Society of Cardiology hypertension guidelines.","authors":"Giuseppe Mancia, Guido Grassi, Sverre E Kjeldsen","doi":"10.1080/08037051.2025.2526549","DOIUrl":"10.1080/08037051.2025.2526549","url":null,"abstract":"","PeriodicalId":9000,"journal":{"name":"Blood Pressure","volume":" ","pages":"2526549"},"PeriodicalIF":1.8,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144494535","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Associations of short-term blood pressure variability with presence and progression of organ damage over five years in ischaemic stroke survivors: the Norwegian Stroke in the Young Study.","authors":"Rune Krogh Eilertsen, Helga Midtbø, Beenish Nawaz, Annette Fromm, Ulrike Waje-Andreassen, Eva Gerdts","doi":"10.1080/08037051.2025.2521523","DOIUrl":"10.1080/08037051.2025.2521523","url":null,"abstract":"<p><strong>Background/aim: </strong>Higher blood pressure (BP) variability (BPV) has been associated with cardiovascular organ damage in cross-sectional studies. Less is known about short-term BPV and organ damage during long-term management of young ischaemic stroke survivors.</p><p><strong>Methods: </strong>Short-term weighted systolic BPV was assessed from ambulatory 24-hour BP recordings three months after the index stroke in 283 ischaemic stroke survivors aged 15-60 years in the prospective Norwegian Stroke in the young study (NOR-SYS). Organ damage was identified as carotid-femoral pulse wave velocity > 10 m/s, carotid intima-media thickness (cIMT) > 0.9 mm, carotid plaque, and abnormal left ventricular (LV) geometry (LV hypertrophy or concentric LV remodelling). Associations of systolic BPV with organ damage at baseline and after five years were identified in logistic regression analyses.</p><p><strong>Results: </strong>Weighted systolic BPV was associated with all types of organ damage both at baseline and at 5-year follow-up in univariable analyses. When adjusted for other cardiovascular risk factors, weighted systolic BPV at baseline remained associated with presence of cIMT > 0.9 mm at follow-up (<i>p</i> = 0.03), independent of BP, body mass index and tobacco smoking at follow-up. Associations with all other organ damage outcomes were lost when adjusted for BP in multivariable analysis. In contrast, systolic BP remained associated with all types of organ damage both at baseline and follow-up (all <i>p</i> < 0.05).</p><p><strong>Conclusions: </strong>In NOR-SYS, the association of higher weighted systolic BPV with cardiac and arterial organ damage was mostly explained by higher systolic BP both at baseline and at 5-year follow-up.</p>","PeriodicalId":9000,"journal":{"name":"Blood Pressure","volume":" ","pages":"2521523"},"PeriodicalIF":1.8,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144309508","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Exploring the impact of short sleep on hypertension prevalence in the Chinese population: dose-response relationships, standardization, and health behaviors.","authors":"Zheng Tian, Qin Han, Xinyi Liu, Hongyi Zhu, Yimiao Li, Nan Zhang, Liwei Jing, Lan Wang","doi":"10.1080/08037051.2025.2542160","DOIUrl":"https://doi.org/10.1080/08037051.2025.2542160","url":null,"abstract":"<p><strong>Aims: </strong>Explore the association between short sleep and hypertension risk in the Chinese population.</p><p><strong>Methods: </strong>Data from the 2020 Chinese Psychological and Behavioral Study of the Population were utilized. Restricted cubic spline models assessed dose-response relationships between sleep duration and hypertension risk. A binary logistic regression model, incorporating propensity score matching, explored the true association between short sleep duration and hypertension risk in the Chinese population. In addition, using binary logistic regression models examined the association between >5 hours of sleep and hypertension risks and the impact of health behaviors on hypertension risk among short sleepers.</p><p><strong>Results: </strong>Sleep duration and hypertension risk exhibited a non-linear U-shaped pattern. ≤5-hour sleepers had a 32% reduced hypertension risk per additional hour of sleep post-matching. >5-hour sleep didn't affect hypertension risk. Among ≤5-hour sleepers, smoking and prolonged fixed position work increased hypertension risk by 128% and 103.4%, respectively, while engaging in physical activity for over six months reduced it by 63.7%.</p><p><strong>Conclusion: </strong>The 5-hour sleep threshold represents a significant turning point for hypertension risk in the Chinese population studied and could serve as a criterion for defining short sleep. Lifestyle modifications such as quitting smoking, adjusting posture during work, and maintaining regular exercise routines can mitigate hypertension risk among individuals with short sleep duration.</p>","PeriodicalId":9000,"journal":{"name":"Blood Pressure","volume":" ","pages":"1-15"},"PeriodicalIF":2.3,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144759065","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Intradialytic Hypotension Pathophysiology and Therapy Update: Review and Update.","authors":"Elmukhtar Habas, Amnna Rayani, Aml Habas, Kalifa Farfar, Eshrak Habas, Khaled Alarbi, Ala Habas, Elmehdi Errayes, Gamal Alfitori","doi":"10.1080/08037051.2025.2469260","DOIUrl":"https://doi.org/10.1080/08037051.2025.2469260","url":null,"abstract":"<p><p>BackgroundIntradialytic hypotension (IDH) is the most prevalent complication during hemodialysis (HD) sessions, affecting 10% to 12% of patients. It is linked with temporary ischemic stress in vital organs, increasing patient mortality. Various definitions of IDH have been proposed, and a strong correlation has been found between patient outcomes and the absolute lowest systolic blood pressure. The most probable underlying pathophysiology of IDH involves a reduced effective blood volume and decreased plasma tonicity. Optimizing the dialysis prescription and interventions during and after the dialysis session is sometimes effective for reducing IDH risk.Aim and MethodThis review discusses the pathophysiology, prevention, and therapy of IDH updates. To achieve this aim, Scopus, EMBASE, PubMed, Google, and Google Scholar were searched for articles published in the last two decades using phrases and keywords.ConclusionIntradialytic pathophysiology is ambiguous and unclear. The evidence for the effectiveness of the known therapies and maneuvers is limited. Ideally, IDH prevention should be the target; however, IDH management is sometimes needed. Different obstacles require further clinical research.</p>","PeriodicalId":9000,"journal":{"name":"Blood Pressure","volume":" ","pages":"1-18"},"PeriodicalIF":1.8,"publicationDate":"2025-02-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143514418","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A randomised trial comparing usual versus strict home blood pressure control in elderly patients with hypertension: protocol and initial progress.","authors":"Dong-Yan Zhang, Yi-Qing Zhang, De-Wei An, Yi-Bang Cheng, Song-Tao Tang, Min Liu, Jue Li, Jan A Staessen, Ji-Guang Wang, Yan Li","doi":"10.1080/08037051.2025.2472192","DOIUrl":"https://doi.org/10.1080/08037051.2025.2472192","url":null,"abstract":"<p><p><b>Objective</b>. The optimal level of home blood pressure (HBP) for the prevention of cardiovascular complications is unknown. The Home Blood Pressure Intervention in the Community Trial (HomeBP, [NCT05858944]) is addressing this issue by randomising elderly hypertensive patients to standard or tight HBP control.<b>Methods and analysis</b>. HomeBP is an investigator-initiated randomised clinical trial with open design and blinded endpoint evaluation. Eligible patients of either sex, aged 60-80 years, having uncontrolled home hypertension (≥135/85 mm Hg) after medication for at least 2 weeks will be recruited nationwide in China at up to 200 community healthcare centres. After stratification for centre and the presence of office hypertension (≥140/90 mm Hg), 10,000 patients will be randomised in a 1:1 proportion to a target HBP of 125-134/75-84 mm Hg or <125/75 mm Hg and followed up for 4 years. The primary outcome is a composite of cardiovascular death, non-fatal myocardial infarction, coronary revascularisation, unstable angina pectoris or heart failure requiring hospitalisation, and non-fatal stroke. Follow-up visits are scheduled monthly for 3 months after randomisation and 3<b>-</b>monthly thereafter. Patients record HBP for 7 consecutive days before every visit. A unique feature of the trial is the information technology setup, allowing the secure and instantaneous flow of HBP and other data to the study coordinating centre, where a standardised HBP report is generated. Hypertension specialists at Ruijin Hospital, Shanghai and at local tertiary hospitals provide treatment recommendations, which are transmitted to the caregivers at the community centres, who then fine-tune the treatment recommendations in a shared decision process with the patients to meet the values and clinical needs of the patients. Currently, 2281 patients have been randomised with no between-group differences in the baseline characteristics.<b>Trial registration number.</b> URL: https://www.clinicaltrials.gov; Unique identifier: NCT05858944.</p>","PeriodicalId":9000,"journal":{"name":"Blood Pressure","volume":" ","pages":"1-16"},"PeriodicalIF":1.8,"publicationDate":"2025-02-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143490615","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Letter to the editor.","authors":"Jorge Polónia, Raul Marques Pereira","doi":"10.1080/08037051.2024.2385159","DOIUrl":"10.1080/08037051.2024.2385159","url":null,"abstract":"","PeriodicalId":9000,"journal":{"name":"Blood Pressure","volume":"33 1","pages":"2385159"},"PeriodicalIF":1.8,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141892745","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Hypertension and its correlation with autonomic nervous system dysfunction, heart rate variability and chronic inflammation.","authors":"Bo He, Dapeng Ji, Bo Zhang","doi":"10.1080/08037051.2024.2405156","DOIUrl":"https://doi.org/10.1080/08037051.2024.2405156","url":null,"abstract":"<p><strong>Objective: </strong>This study investigates the relationship between hypertension, dysregulation of the autonomic nervous system, heart rate variability (HRV), and chronic inflammation.</p><p><strong>Methods: </strong>We analysed a cohort of 50 hypertensive patients treated at the affiliated Hospital of Jianghan University. The average systolic and diastolic blood pressures (BPs) in this group were 155.26 and 95.32 mmHg, respectively. A control group of 50 healthy volunteers, undergoing routine physical examinations at the same hospital, was also analysed.</p><p><strong>Results: </strong>The average systolic BP of the control group was 115.64 ± 10.27 mmHg, and the average diastolic BP was 75.33 ± 8.25 mmHg. In contrast, the experimental group exhibited an average systolic BP of 155.26 ± 20.13 mmHg and an average diastolic BP of 95.32 ± 12.16 mmHg. Both systolic and diastolic BPs were significantly higher in the hypertensive group (<i>p</i> < 0.05). The experimental group also demonstrated reduced HRV and skin conductance response, alongside increased BP variability (BPV), urinary epinephrine levels and prolonged pupillary light reaction time compared to controls (<i>p</i> < 0.05). Notably, Standard Deviation of Normal to Normal Intervals (SDNN) and Root Mean Square of Successive Differences (RMSSD) values were significantly lower in the experimental group (<i>p</i> < 0.05). Furthermore, levels of inflammatory markers such as CRP, TNF-α, IL-6 and IL-1β were markedly elevated in hypertensive patients (<i>p</i> < 0.05). Negative correlations were observed between systolic and diastolic BP with HRV metrics, while positive correlations were found between BP and BPV as well as urinary adrenaline levels.</p><p><strong>Conclusions: </strong>The findings indicate that hypertension is closely associated with autonomic nervous system dysfunction, reduced HRV and increased chronic inflammation. A comprehensive approach to hypertension management should integrate these interrelated physiological and pathological mechanisms, with potential therapeutic interventions targeting autonomic function and inflammatory states.</p>","PeriodicalId":9000,"journal":{"name":"Blood Pressure","volume":"33 1","pages":"2405156"},"PeriodicalIF":1.8,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142280147","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A sham-controlled randomised pilot trial on baroreflex activation therapy in patients with resistant hypertension: What will the future hold?","authors":"D Gordin, R Simonsen, I Tikkanen","doi":"10.1080/08037051.2024.2417887","DOIUrl":"10.1080/08037051.2024.2417887","url":null,"abstract":"","PeriodicalId":9000,"journal":{"name":"Blood Pressure","volume":"33 1","pages":"2417887"},"PeriodicalIF":1.8,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142494646","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association of childhood socioeconomic status with adulthood maximal exercise blood pressure: the Cardiovascular Risk in Young Finns Study.","authors":"Erika Kähönen, Emilia Kähönen, Kristiina Pälve, Janne Hulkkonen, Mika Kähönen, Olli T Raitakari, Nina Hutri, Terho Lehtimäki, Heikki Aatola","doi":"10.1080/08037051.2024.2323987","DOIUrl":"10.1080/08037051.2024.2323987","url":null,"abstract":"<p><strong>Purpose: </strong>Socioeconomic status has been related to resting blood pressure (BP) levels at different stages of life. However, the association of childhood socioeconomic status (SES) and adulthood exercise BP is largely unknown. Therefore, we studied the association of childhood SES with adulthood maximal exercise BP.</p><p><strong>Materials and methods: </strong>This investigation consisted of 373 individuals (53% women) participating in the Cardiovascular Risk in Young Finns Study who had data concerning family SES in childhood (baseline in 1980, at age of 6-18 years) and exercise BP response data in adulthood (follow-up in adulthood in 27-29 years since baseline). A maximal cardiopulmonary exercise test with BP measurements was performed by participants, and peak exercise BP was measured.</p><p><strong>Results: </strong>In stepwise multivariable analysis including childhood risk factors and lifestyle factors (body mass index, systolic BP, low-density lipoprotein cholesterol, high-density lipoprotein cholesterol, triglycerides, insulin, fruit consumption, vegetable consumption, and physical activity), lower family SES in childhood was associated with higher maximal exercise BP in adulthood (β value ± SE, 1.63 ± 0.77, <i>p</i> = 0.035). The association remained significant after further adjustment with participants SES in adulthood (β value ± SE, 1.68 ± 0.65, <i>p</i> = 0.011) and after further adjustment with adulthood body-mass index, systolic BP, maximal exercise capacity, and peak heart rate in exercise (β value ± SE, 1.25 ± 0.56, <i>p</i> = 0.027).</p><p><strong>Conclusions: </strong>These findings suggest that lower childhood family SES is associated with higher maximal exercise BP in adulthood.</p>","PeriodicalId":9000,"journal":{"name":"Blood Pressure","volume":"33 1","pages":"2323987"},"PeriodicalIF":1.8,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140093430","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Long-term trajectory of renal dysfunction and related risk factors in patients with apparently treatment-resistant and non-resistant arterial hypertension.","authors":"Zdeněk Ramík, Jan Václavík, Tomáš Kvapil, Libor Jelínek, Eva Kociánová, Monika Kamasová, Klára Benešová, Jiří Jarkovský, Martin Drápela, Zdeněk Lys","doi":"10.1080/08037051.2024.2353836","DOIUrl":"https://doi.org/10.1080/08037051.2024.2353836","url":null,"abstract":"<p><p><b>Objectives:</b> Evidence suggests that renal function increasingly deteriorates in patients with apparently treatment-resistant hypertension (ATRH) in comparison with those who have non-resistant arterial hypertension (NAH). We aimed to assess the long-term decline in renal function between these patient groups and identify specific risk factors contributing to the progression of renal dysfunction. <b>Methods:</b> Data for 265 patients with ATRH and NAH in a hypertension excellence centre were retrospectively evaluated. Demographic characteristics, co-morbidities, laboratory findings, secondary causes of hypertension, medication and exposure to contrast agents were assessed. To address differences between groups, adjustment with linear mixed-effect models was used. <b>Results:</b> Data from the first 4 years of follow-up were evaluated. After adjustment for age and diabetes, which were identified as independent risk factors for renal dysfunction progression in the study cohort, the mean decrease in estimated glomerular filtration rate per year was steeper with ATRH than with NAH (-1.49 <i>vs.</i> -0.65 mL/min/1.73 m² per year; difference in slope, 0.83 mL/min/1.73 m² per year; 95% confidence interval [CI]: 0.25-1.41, <i>p</i> = 0.005). In subgroup analyses, without Holm-Bonferroni correction, the prescription of MRA indicated a faster decline in renal function in ATRH. Following correction, no specific therapeutic risk factor was associated with faster progression of renal dysfunction. <b>Conclusions:</b> Renal function declines twice as fast with ATRH compared with NAH, independently of age and diabetes. Larger studies are needed to reveal risk factors for renal dysfunction in patients with hypertension.</p>","PeriodicalId":9000,"journal":{"name":"Blood Pressure","volume":"33 1","pages":"2353836"},"PeriodicalIF":1.8,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141282960","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}