Clinical medicine. Case reports最新文献_第3页

Malignant myeloma in a patient after treatment for osteoporosis with teriparatide; a rare coincidence. 特立帕肽治疗骨质疏松症后发生恶性骨髓瘤1例一个罕见的巧合。

Clinical medicine. Case reports Pub Date : 2008-08-29 eCollection Date: 2008-01-01 DOI: 10.4137/ccrep.s1026

Terje Forslund, Anna-Mari Koski, Arvo Koistinen, Anu Sikiö

{"title":"Malignant myeloma in a patient after treatment for osteoporosis with teriparatide; a rare coincidence.","authors":"Terje Forslund, Anna-Mari Koski, Arvo Koistinen, Anu Sikiö","doi":"10.4137/ccrep.s1026","DOIUrl":"https://doi.org/10.4137/ccrep.s1026","url":null,"abstract":"A breakthrough in understanding of mechanisms of bone structure regulation has brought about the introduction of the new synthetic recombinant human parathyroid hormone 1-34 (PTH1-34; Teriparatide) in the treatment of osteoporosis. These mechanisms, involving the RANKL, RANK, and osteoprotegerin system, are also known to be involved in malignant myeloma (MM) and tumor and bone metastasis development. We report a case in which MM was found after treatment of osteoporosis with teriparatide. We were unable to demonstrate any direct association between the MM and teriparatide treatment. However, it seemed intriguing that similar mechanisms are activated in the development of MM as those being working during teriparatide treatment. In the view of our case, we propose that MM by examination of serum protein fraction should be searched for prior to treatment with teriparatide as it is an exclusion criterion in teriparatide treatment of secondary osteoporosis. A search for other metastatic diseases prior to teriparatide treatment should eventually also be considered. The theoretical basis for our proposal is discussed. ","PeriodicalId":89909,"journal":{"name":"Clinical medicine. Case reports","volume":"1 ","pages":"119-22"},"PeriodicalIF":0.0,"publicationDate":"2008-08-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.4137/ccrep.s1026","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"31823991","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 7

Nizatidine Improves Impaired Salivary Secretion in GERD. 尼扎替丁改善胃食管反流中受损的唾液分泌。

Clinical medicine. Case reports Pub Date : 2008-08-19 eCollection Date: 2008-01-01 DOI: 10.4137/ccrep.s870

Yoshihisa Urita, Toshiyasu Watanabe, Kazuo Hike, Makie Nanami, Tadashi Maeda, Yosuke Sasaki, Asuka Nakayama, Takamasa Ishii, Kaoru Domon, Susumu Ishihara, Masaki Sanaka, Hitoshi Nakajima, Motonobu Sugimoto

{"title":"Nizatidine Improves Impaired Salivary Secretion in GERD.","authors":"Yoshihisa Urita, Toshiyasu Watanabe, Kazuo Hike, Makie Nanami, Tadashi Maeda, Yosuke Sasaki, Asuka Nakayama, Takamasa Ishii, Kaoru Domon, Susumu Ishihara, Masaki Sanaka, Hitoshi Nakajima, Motonobu Sugimoto","doi":"10.4137/ccrep.s870","DOIUrl":"https://doi.org/10.4137/ccrep.s870","url":null,"abstract":"Unlabelled: During esophageal acid clearance, salivation plays an important role in defending the esophageal mucosa. Nizatidine, a histamine H2 receptor antagonist, inhibits acetylcholine esterase, with a resultant increase in acetylcholine. We experienced a patient with gastroesophageal reflux disease (GERD) and impaired salivary secretion who has been successfully treated with nizatidine.Case report: A 63-year-old female visited our hospital with complaints of heartburn and continuous laryngeal discomfort. Saliva scintigraphy was performed to evaluate the salivary function. Washout ratio was decreased to be 25%-40% in individual salivary gland. After the treatment with nizatidine, salivary scintigraphy demonstrated the increased washout ratios. The values of both parotid glands increased up to 90%, whereas those of submandibular glands improved to be around a normal range. GERD symptoms disappeared completely after treatment. In conclusion, nizatidine may be one of therapeutic options for low salivary excretion.","PeriodicalId":89909,"journal":{"name":"Clinical medicine. Case reports","volume":"1 ","pages":"113-7"},"PeriodicalIF":0.0,"publicationDate":"2008-08-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.4137/ccrep.s870","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"31823990","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Surgical anatomy of large retroperitoneal teratomas in infants: report of two cases. 婴儿腹膜后大畸胎瘤的外科解剖:附2例报告。

Clinical medicine. Case reports Pub Date : 2008-07-31 eCollection Date: 2008-01-01 DOI: 10.4137/ccrep.s907

Ralf-Bodo Tröbs, Christian Geyer, Wolfgang Hirsch, Andrea Tannapfel

引用次数: 8

Successful management of multifactorial colitis in a recipient of hematopoietic stem cell transplant: a case report. 成功管理多因素结肠炎的受体造血干细胞移植:一个案例报告。

Clinical medicine. Case reports Pub Date : 2008-07-29 eCollection Date: 2008-01-01 DOI: 10.4137/ccrep.s838

Khalid A Al-Anazi, Asma M Al-Jasser, Amal Abdulwahab, Entezam Sahovic, Hadeel Almana, Mohammed A Al Fadda

引用次数: 0

Multiple complications in a sickle cell disease patient: a case report. 镰状细胞病患者的多重并发症1例

Clinical medicine. Case reports Pub Date : 2008-07-08 eCollection Date: 2008-01-01 DOI: 10.4137/ccrep.s812

J A Olaniyi

引用次数: 3

Dissecting aneurysms of bilateral anterior cerebral artery complicated by subarachnoid hemorrhage after cerebral infarction: a case report. 脑梗死后双侧大脑前动脉夹层动脉瘤并发蛛网膜下腔出血1例。

Clinical medicine. Case reports Pub Date : 2008-07-02 eCollection Date: 2008-01-01 DOI: 10.4137/ccrep.s833

Akihiro Kurosu, Shizuo Hatashita, Hideo Ueno

{"title":"Dissecting aneurysms of bilateral anterior cerebral artery complicated by subarachnoid hemorrhage after cerebral infarction: a case report.","authors":"Akihiro Kurosu, Shizuo Hatashita, Hideo Ueno","doi":"10.4137/ccrep.s833","DOIUrl":"https://doi.org/10.4137/ccrep.s833","url":null,"abstract":"Introduction: Intracranial dissecting aneurysms have been increased due to recent advancements in diagnostic imaging. However there have been little article with subarachnoid hemorrhage and cerebral infarction occurring almost at the same time. We performed the surgical treatment and obtained good result.Case presentation: A 47-year-old male presented to our hospital with chief complaints of sudden headache and mild paralysis of the left lower extremity. Brain imaging at admission revealed cerebral infarction in the right frontal lobe and subarachnoid hemorrhage in the frontal convexy and anterior interhemispheric fissure. The left and right internal carotid angiography showed a bulging cerebral aneurysm at the left A1-A2 junction and stenosis and arterial dissections in the peripheral of the bilateral anterior cerebral artery. Wrapping was performed for the dissecting aneurysm of the left anterior cerebral artery. For the right anterior cerebral artery, trapping was performed at the A2 segment without vascular anastomosis. The patient's postoperative course was uneventful.Conclusion: A consensus has not been reached on the treatment for intracranial dissecting aneurysms. Proximal trapping without vascular reconstruction was performed for the right anterior cerebral artery without vascular anastomosis to prevent rebleeding. However no symptoms of neurological deficiency were observed. Proximal trapping of dissecting aneurysm seems to be a good option when patient's functional and life prognosis are taken into account in case that vascular reconstruction will be anticipated difficulty.","PeriodicalId":89909,"journal":{"name":"Clinical medicine. Case reports","volume":"1 ","pages":"93-6"},"PeriodicalIF":0.0,"publicationDate":"2008-07-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.4137/ccrep.s833","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"31823986","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Common variable immunodeficiency and peripheral lung nodule. 常见的变异性免疫缺陷和周围性肺结节。

Clinical medicine. Case reports Pub Date : 2008-06-20 eCollection Date: 2008-01-01 DOI: 10.4137/ccrep.s735

Miguel Ángel Núñez, Javier Velasco, Jose Luis Hernandez, Cristina Castrillo, Maria Luisa Cagigal

引用次数: 0

Forty years abuse of baking soda, rhabdomyolysis, glomerulonephritis, hypertension leading to renal failure: a case report. 滥用小苏打四十年，横纹肌溶解，肾小球肾炎，高血压导致肾功能衰竭:1例报告。

Clinical medicine. Case reports Pub Date : 2008-06-17 eCollection Date: 2008-01-01 DOI: 10.4137/ccrep.s888

Terje Forslund, Arvo Koistinen, Jorma Anttinen, Bodo Wagner, Marja Miettinen

引用次数: 6

Fulminant klebssiella pneumoniae pneumonia in immunocompetent non alcoholic patient. 免疫功能正常非酒精患者的暴发性肺炎克雷伯氏菌肺炎。

Clinical medicine. Case reports Pub Date : 2008-06-10 eCollection Date: 2008-01-01 DOI: 10.4137/ccrep.s761

Z Benyashvili, A Djirbe, N Assy

引用次数: 0

Insufficiency fracture in the para-acetabulum, with features mimicking those of a malignant bone tumor. 髋臼旁不全性骨折，特征与恶性骨肿瘤相似。

Clinical medicine. Case reports Pub Date : 2008-06-06 eCollection Date: 2008-01-01 DOI: 10.4137/ccrep.s803

Akio Sakamoto, Takuaki Yamamoto, Kazuhiro Tanaka, Shuichi Matsuda, Tatsuya Yoshida, Yukihide Iwamoto

{"title":"Insufficiency fracture in the para-acetabulum, with features mimicking those of a malignant bone tumor.","authors":"Akio Sakamoto, Takuaki Yamamoto, Kazuhiro Tanaka, Shuichi Matsuda, Tatsuya Yoshida, Yukihide Iwamoto","doi":"10.4137/ccrep.s803","DOIUrl":"https://doi.org/10.4137/ccrep.s803","url":null,"abstract":"Para-acetabular insufficiency fractures are rare and exceedingly difficult to diagnose without a high index of suspicion, since the images mimic those of bone tumors. We herein present the case of a 55-year-old woman who suffered from hip pain with subacute onset. She had undergone a hysterectomy-ovariectomy due to endometriosis when she was 41 years old. Her bone mineral density was normal due to supplemental treatment with female hormones. About 3 months after onset, she was referred to our institute with a diagnosis of pelvic bone tumor. Plain radiographs and computed tomography showed irregular osteosclerosis in the para-acetabulum. Bone scintigraphy demonstrated uptake in the para-acetabulum. Magnetic resonance imaging showed abnormal signal with low-signal intensity on T1-weighted images and high-signal intensity on T2-weighted images throughout the entire hemipelvic bone. Since the pain continued for more than 3 months, open biopsy was undertaken and the lesion was found to be non-neoplastic. Six months after onset, the pain disappeared. The clinical course suggested a diagnosis of insufficiency fracture in the para-acetabulum. Para-acetabular insufficiency fractures should always be considered in cases of hip pain, even in patients with prolonged symptoms. ","PeriodicalId":89909,"journal":{"name":"Clinical medicine. Case reports","volume":"1 ","pages":"73-6"},"PeriodicalIF":0.0,"publicationDate":"2008-06-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.4137/ccrep.s803","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"31823981","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 4