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An Acute Leukaemia Masquerading as Immune Thrombocytopaenic Purpura (ITP)? A Case Report. 伪装成免疫性血小板增多性紫癜（ITP）的急性白血病？病例报告。
Clinical medicine. Case reports Pub Date : 2009-04-17 eCollection Date: 2009-01-01 DOI: 10.4137/ccrep.s2394
J A Olaniyi
{"title":"An Acute Leukaemia Masquerading as Immune Thrombocytopaenic Purpura (ITP)? A Case Report.","authors":"J A Olaniyi","doi":"10.4137/ccrep.s2394","DOIUrl":"10.4137/ccrep.s2394","url":null,"abstract":"<p><p>This is a case report of a 35 year old female with diagnosed Immune Thrombocytopaenic Purpura (ITP) that was strangely followed by acute myeloid leukaemia at 10 months post diagnosis of ITP. She was managed as ITP using prednisolone 45 mg daily for 10 months with good response. She also synchronously carried a pregnancy to term and safe delivery. Shortly after delivery, she represented with gingival bleeding and peripheral film review and subsequent bone marrow cytology was in keeping with AML-M4 subtype. She died shortly after diagnosis without being able to receive chemotherapy. </p>","PeriodicalId":89909,"journal":{"name":"Clinical medicine. Case reports","volume":"2 ","pages":"31-4"},"PeriodicalIF":0.0,"publicationDate":"2009-04-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3785378/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"31825085","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Case of Tubulointerstitial Nephritis and Uveitis (TINU) Syndrome with High ASLO Titer. 高ASLO滴度肾小管间质性肾炎及葡萄膜炎综合征1例。
Clinical medicine. Case reports Pub Date : 2009-04-09 eCollection Date: 2009-01-01 DOI: 10.4137/ccrep.s2299
Yasuyo Kashiwagi, Shunsuke Suzuki, Tao Fujioka, Shingo Oana, Hisashi Kawashima, Kouji Takekuma, Akinori Hoshika
{"title":"A Case of Tubulointerstitial Nephritis and Uveitis (TINU) Syndrome with High ASLO Titer.","authors":"Yasuyo Kashiwagi,&nbsp;Shunsuke Suzuki,&nbsp;Tao Fujioka,&nbsp;Shingo Oana,&nbsp;Hisashi Kawashima,&nbsp;Kouji Takekuma,&nbsp;Akinori Hoshika","doi":"10.4137/ccrep.s2299","DOIUrl":"https://doi.org/10.4137/ccrep.s2299","url":null,"abstract":"<p><p>Tubulointerstitial nephritis and uveitis (TINU) syndrome is a rare autoimmune disease and the pathogenesis is still unknown. We report a case of TINU syndrome with high ASLO titer. Uveitis improved and urine β2-MG normalized with low dose systemic predonisolone and cyclosporin A. The high ASLO titer in early phase suggested that streptococcal infection might have triggered TINU syndrome. Lymphocyte phenotypes normalized after treatment with low dose systemic predonisolone and cyclosporin A. </p>","PeriodicalId":89909,"journal":{"name":"Clinical medicine. Case reports","volume":"2 ","pages":"27-30"},"PeriodicalIF":0.0,"publicationDate":"2009-04-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.4137/ccrep.s2299","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"31825084","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 6
A case of large solitary fibrous tumor in the retroperitoneum. 腹膜后大孤立性纤维性肿瘤1例。
Clinical medicine. Case reports Pub Date : 2009-03-23 eCollection Date: 2009-01-01 DOI: 10.4137/ccrep.s2356
Takeo Nomura, Ryuta Satoh, Kenji Kashima, Mutsushi Yamasaki, Kenichi Hirai, Fuminori Satoh, Hiromitsu Mimata
{"title":"A case of large solitary fibrous tumor in the retroperitoneum.","authors":"Takeo Nomura,&nbsp;Ryuta Satoh,&nbsp;Kenji Kashima,&nbsp;Mutsushi Yamasaki,&nbsp;Kenichi Hirai,&nbsp;Fuminori Satoh,&nbsp;Hiromitsu Mimata","doi":"10.4137/ccrep.s2356","DOIUrl":"https://doi.org/10.4137/ccrep.s2356","url":null,"abstract":"<p><p>Solitary fibrous tumor (SFT) is a rare spindle cell neoplasm mainly originated in the pleural cavity. We report here an unusual case of a large SFT in the retroperitoneum. A 27-year-old female complaining of a palpable mass in the right flank with dull pain was admitted to our hospital with the diagnosis of right retroperitoneal tumor. Computed tomography (CT) and magnetic resonance imaging (MRI) showed a large retroperitoneal tumor arising from latissimus dorsi muscle. Surgical findings revealed a partly encapsulated tumor and complete resection of tumor concomitantly with right kidney, 11th and 12th ribs, and diaphragm was performed. Pathological examination demonstrated the tumor to be composed of increased mitotic activity and cellularity of spindle cells with a collagenous matrix. Immunohistochemical staining was positive for CD34, vimentin, and basic fibroblast growth factor (bFGF) and negative for CD31, cytokeratin, desmin, S-100p, smooth muscle actin, Bcl-2, and insulin-like growth factor (IGF) with Ki-67 labeling index of 0.1%. Based on pathological features, diagnosis of SFT in the retroperitoneum was confirmed. To our knowledge, this is the first report of an SFT arising from latissimus dorsi muscle and it is important to include SFT in the differential diagnosis of retroperitoneal tumors that caused considerable diagnostic problems due to its unusual site of origin. </p>","PeriodicalId":89909,"journal":{"name":"Clinical medicine. Case reports","volume":"2 ","pages":"21-5"},"PeriodicalIF":0.0,"publicationDate":"2009-03-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.4137/ccrep.s2356","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"31825083","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 7
Bacteremia due to clostridium difficile: case report and review of the literature. 艰难梭菌引起的菌血症:病例报告及文献复习。
Clinical medicine. Case reports Pub Date : 2009-02-17 eCollection Date: 2009-01-01 DOI: 10.4137/ccrep.s2204
Cherag Daruwala, Giancarlo Mercogliano, Gary Newman, Mark J Ingerman
{"title":"Bacteremia due to clostridium difficile: case report and review of the literature.","authors":"Cherag Daruwala,&nbsp;Giancarlo Mercogliano,&nbsp;Gary Newman,&nbsp;Mark J Ingerman","doi":"10.4137/ccrep.s2204","DOIUrl":"https://doi.org/10.4137/ccrep.s2204","url":null,"abstract":"<p><strong>Objective: </strong>The purpose of this study is to report a case of C. difficile bacteremia in a Crohn's disease patient and to review the literature on previously reported cases.</p><p><strong>Methods: </strong>Searches of MEDLINE and PubMed databases were made.</p><p><strong>Results: </strong>We report the first case of C. difficile bacteremia in a Crohn's disease patient. There are 15 other reported cases of C. difficile bacteremia reported in the literature. We found that the majority of patients (10 of 15 patients) had polymicrobial bacteremia and that the overall mortality rate is significant, with 6 of 15 reported patients dying.</p><p><strong>Conclusion: </strong>In conclusion, we find that C. difficile bacteremia is associated with a significant mortality rate and it would seem prudent to consider aggressive antibiotic therapy.</p>","PeriodicalId":89909,"journal":{"name":"Clinical medicine. Case reports","volume":"2 ","pages":"5-9"},"PeriodicalIF":0.0,"publicationDate":"2009-02-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.4137/ccrep.s2204","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"31825080","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 11
Acute autonomic, sensory and motor neuropathy associated with meningoencephalitis. 与脑膜脑炎相关的急性自主神经、感觉和运动神经病变。
Clinical medicine. Case reports Pub Date : 2009-02-12 eCollection Date: 2009-01-01 DOI: 10.4137/ccrep.s2194
Satoko Kinoshita, Kazuma Sugie, Hiroshi Kataoka, Miho Sugie, Makito Hirano, Satoshi Ueno
{"title":"Acute autonomic, sensory and motor neuropathy associated with meningoencephalitis.","authors":"Satoko Kinoshita,&nbsp;Kazuma Sugie,&nbsp;Hiroshi Kataoka,&nbsp;Miho Sugie,&nbsp;Makito Hirano,&nbsp;Satoshi Ueno","doi":"10.4137/ccrep.s2194","DOIUrl":"https://doi.org/10.4137/ccrep.s2194","url":null,"abstract":"<p><p>We report the first case of acute autonomic, motor and sensory neuropathy (AASMN) associated with meningoencephalitis. A 62-year-old man presented with fever, neck stiffness, and coma. Respiratory failure developed. Magnetic resonance images showed an abnormality in the medial temporal lobe. Cerebrospinal fluid analysis revealed pleocytosis with a high protein level. Intensive care gradually improved the consciousness level, but paralysis of the four extremities persisted. Nerve conduction studies revealed demyelinating sensory and motor polyneuropathy. Severe orthostatic hypotension, urinary retention, and constipation were also present. Clinical autonomic tests suggested both sympathetic and parasympathetic dysfunction. After intravenous immunoglobulin therapy, motor and sensory symptoms resolved rapidly; dysautonomia resolved gradually over the next 2 months. The response to immunological therapy and the presence of antecedent infection suggest that AASMN is a postinfectious, immune-mediated, autonomic, sensory and motor nervous system dysfunction. </p>","PeriodicalId":89909,"journal":{"name":"Clinical medicine. Case reports","volume":"2 ","pages":"17-20"},"PeriodicalIF":0.0,"publicationDate":"2009-02-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.4137/ccrep.s2194","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"31825082","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Endobronchial Epstein-Barr Virus Associated Post-transplant Lymphoproliferative Disorder in Hematopoietic Stem Cell Transplantation. 支气管内爱泼斯坦-巴尔病毒相关的造血干细胞移植后淋巴细胞增生性疾病。
Clinical medicine. Case reports Pub Date : 2009-02-03 eCollection Date: 2009-01-01 DOI: 10.4137/ccrep.s2084
S Feuillet, V Meignin, J Brière, P Brice, V Rocha, G Socié, A Tazi, A Bergeron
{"title":"Endobronchial Epstein-Barr Virus Associated Post-transplant Lymphoproliferative Disorder in Hematopoietic Stem Cell Transplantation.","authors":"S Feuillet,&nbsp;V Meignin,&nbsp;J Brière,&nbsp;P Brice,&nbsp;V Rocha,&nbsp;G Socié,&nbsp;A Tazi,&nbsp;A Bergeron","doi":"10.4137/ccrep.s2084","DOIUrl":"https://doi.org/10.4137/ccrep.s2084","url":null,"abstract":"<p><p>The Epstein-Barr virus (EBV) associated Post-Transplant Lymphoproliferative Disorders (PTLD) are increasingly recognized as a fatal complication of hematological stem cell transplantation (HSCT). Thoracic involvement, that may be isolated or part of a disseminated disease, usually encompasses pulmonary nodules or masses and mediastinal lymph node enlargement. The current case study presents 2 patients who underwent HSCT, one allogenic and the other autologous, who developed an exceptional endobronchial EBV related PTLD. The first patient had a fleshy white endobronchial mass resulting in a right upper lobe atelectasis and the second had an extensive necrotising mucosa from trachea to both basal bronchi without any significant change of lung parenchyma on the CT scan. In both cases, the diagnosis was made by bronchial biopsies. Physicians should be aware of an endobronchial pattern of EBV associated PTLD after HSCT to permit quick diagnosis and therapeutic intervention. </p>","PeriodicalId":89909,"journal":{"name":"Clinical medicine. Case reports","volume":"2 ","pages":"11-5"},"PeriodicalIF":0.0,"publicationDate":"2009-02-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.4137/ccrep.s2084","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"31825081","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Photon-deficient Mass on FDG-PET Scan in Renal Cell Carcinoma: A Case Report. 肾细胞癌FDG-PET扫描的缺光子团1例报告。
Clinical medicine. Case reports Pub Date : 2008-12-23 eCollection Date: 2008-01-01 DOI: 10.4137/ccrep.s724
George Shih, Wei-Jen Shih, Bonnie Mitchell, Primo P Milan
{"title":"Photon-deficient Mass on FDG-PET Scan in Renal Cell Carcinoma: A Case Report.","authors":"George Shih,&nbsp;Wei-Jen Shih,&nbsp;Bonnie Mitchell,&nbsp;Primo P Milan","doi":"10.4137/ccrep.s724","DOIUrl":"https://doi.org/10.4137/ccrep.s724","url":null,"abstract":"<p><p>F-18 Fluorodeoxyglucose Positron Emission Tomography imaging (F-18 FDG PET) detects malignancies depending on the uptake profile of glycolysis of tumors; however, the role of FDG PET is limited in the evaluation of primary renal malignancy because of low FDG uptake by renal cell carcinoma and also because normal urinary excretion of FDG seen in the images. A patient with renal cell carcinoma whose FDG PET imaging study incidentally shows a photon-deficient mass in the upper pole of the right kidney is present here. The diagnosis is also validated by the histopathological findings of tumor necrosis, hemorrhage, and scars. </p>","PeriodicalId":89909,"journal":{"name":"Clinical medicine. Case reports","volume":"2 ","pages":"1-4"},"PeriodicalIF":0.0,"publicationDate":"2008-12-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.4137/ccrep.s724","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"31825079","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A case report of hepatitis e infection leading to acute liver failure and transplantation. 戊型肝炎感染致急性肝衰竭及肝移植1例报告。
Clinical medicine. Case reports Pub Date : 2008-12-02 eCollection Date: 2008-01-01 DOI: 10.4137/ccrep.s845
P Paskaran, A U Murugananthan, V Manglam, J Arnold, A Pal
{"title":"A case report of hepatitis e infection leading to acute liver failure and transplantation.","authors":"P Paskaran,&nbsp;A U Murugananthan,&nbsp;V Manglam,&nbsp;J Arnold,&nbsp;A Pal","doi":"10.4137/ccrep.s845","DOIUrl":"https://doi.org/10.4137/ccrep.s845","url":null,"abstract":"","PeriodicalId":89909,"journal":{"name":"Clinical medicine. Case reports","volume":"1 ","pages":"133-5"},"PeriodicalIF":0.0,"publicationDate":"2008-12-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.4137/ccrep.s845","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"31825078","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 6
Diagnosis of paracardiac castleman disease by dynamic gadolinium-enhanced first pass perfusion magnetic resonance imaging. 动态钆增强第一次灌注磁共振成像诊断心旁castleman病。
Clinical medicine. Case reports Pub Date : 2008-10-01 eCollection Date: 2008-01-01 DOI: 10.4137/ccrep.s732
Andrew Crean, Narinder Paul, Naeem Merchant, Lianne Singer, Yves Provost
{"title":"Diagnosis of paracardiac castleman disease by dynamic gadolinium-enhanced first pass perfusion magnetic resonance imaging.","authors":"Andrew Crean,&nbsp;Narinder Paul,&nbsp;Naeem Merchant,&nbsp;Lianne Singer,&nbsp;Yves Provost","doi":"10.4137/ccrep.s732","DOIUrl":"https://doi.org/10.4137/ccrep.s732","url":null,"abstract":"<p><p>Summary Castleman disease is an uncommon disorder affecting the lymphatic system and is characterised by atypical lymphocyte proliferation. The usual clinical presentation is of a solitary mass lesion, frequently within the thorax. A number of different imaging findings have been reported on CT and MRI. We present a case of paracardiac Castleman disease where the diagnosis was suggested by dramatic enhancement of the tumour mass during a dynamic MR perfusion sequence. To our knowledge this is the first report of the use of a first pass bolus tracking technique in the diagnosis of Castleman disease. </p>","PeriodicalId":89909,"journal":{"name":"Clinical medicine. Case reports","volume":"1 ","pages":"127-31"},"PeriodicalIF":0.0,"publicationDate":"2008-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.4137/ccrep.s732","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"31825077","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
A rare embryologic variation: anterior communicating artery aneurysm associated with carotid-anterior cerebral artery anastomosis or infraoptic course of the anterior cerebral artery. 一罕见的胚胎变异:前交通动脉瘤伴颈动脉-大脑前动脉吻合或大脑前动脉的视下走行。
Clinical medicine. Case reports Pub Date : 2008-09-24 eCollection Date: 2008-01-01 DOI: 10.4137/ccrep.s918
Alaattin Yurt, Kubilay Uçar, Füsun Ozer, Ismail Oran, Nuri Arda
{"title":"A rare embryologic variation: anterior communicating artery aneurysm associated with carotid-anterior cerebral artery anastomosis or infraoptic course of the anterior cerebral artery.","authors":"Alaattin Yurt,&nbsp;Kubilay Uçar,&nbsp;Füsun Ozer,&nbsp;Ismail Oran,&nbsp;Nuri Arda","doi":"10.4137/ccrep.s918","DOIUrl":"https://doi.org/10.4137/ccrep.s918","url":null,"abstract":"<p><p>Aneurysms of the complex of the anterior cerebral artery are frequently associated with anatomic variations of the circle of Willis. We describe a case of aneurysmal rupture of the anterior communicating artery, a variant of the anterior cerebral artery. The aneurysm appeared to be situated on this vessel proximal to the infered site of the AcoA. Surgery was performed at the 6th day after hemorrhage. The anterior communicating artery aneurysm was clipped. The post operative course was unventful, with complete recovery. In our case, an extremely rare variation of the proximal tract of the anterior cerebral artery, i.e. an infraoptic course of the proximal precommunicating tract under the optic nerve, with the distal A1 tract anterior to the chiasm and positioned between the optic nerves, is presented. </p>","PeriodicalId":89909,"journal":{"name":"Clinical medicine. Case reports","volume":"1 ","pages":"123-5"},"PeriodicalIF":0.0,"publicationDate":"2008-09-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.4137/ccrep.s918","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"31825076","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 5
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