BJOG: An International Journal of Obstetrics & Gynaecology最新文献

{"title":"A Holistic Approach to Understanding and Mitigating the Rising Burden of Maternal Chronic Conditions","authors":"Binglin Li, Yueqi Feng, Ruijuan Chen","doi":"10.1111/1471-0528.18111","DOIUrl":"https://doi.org/10.1111/1471-0528.18111","url":null,"abstract":"","PeriodicalId":8984,"journal":{"name":"BJOG: An International Journal of Obstetrics & Gynaecology","volume":"15 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-02-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143451590","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Free Foetal Haemoglobin in Severe Early‐Onset Foetal Growth Restriction: A Prospective Multi‐Centre Study","authors":"Adam Brook, Georgia Baynes, Jonathan Scargill, Angelos Evangelinos, Charlotte Brennan‐Richardson, Freya Dow, Yuval Ginsberg, Tal Weissbach, Jana Brodszki, Eva Hansson, Anke Diemert, Kurt Hecher, Katarzyna Maksym, Neil Marlow, Rebecca N. Spencer, Anna L. David, Stefan R. Hansson, Paul Brownbill","doi":"10.1111/1471-0528.18104","DOIUrl":"https://doi.org/10.1111/1471-0528.18104","url":null,"abstract":"ObjectiveTo assess foetal circulating free foetal haemoglobin (fHbF) levels and heme defences, correlated to foetal circulatory biometry and foetal sex in severe early‐onset foetal growth restriction (FGR).Design, Setting and PopulationA prospective study severe early‐onset foetal growth restriction pregnancies with close clinical management (estimated foetal weight (EFW) &lt; 3rd centile and &lt; 600 g at 20–26 + 6 weeks; <jats:italic>N</jats:italic> = 20).Method &amp; Main Outcome MeasuresTemporal foetal vascular obstetric biometry was recorded. Cord blood fHbF and key heme‐scavenger defences were measured and compared with normal term births (<jats:italic>N</jats:italic> = 26) and births with late‐onset FGR (<jats:italic>N</jats:italic> = 12).ResultsfHbF was elevated in early‐onset FGR compared with normal pregnancy: 0.437(0.337/0.753) mg/mL; and 0.098 (0.045/0.264) mg/mL, respectively (<jats:italic>p</jats:italic> &lt; 0.0001); whilst hemopexin was downregulated in early‐ (<jats:italic>p</jats:italic> &lt; 0.001) and late‐onset FGR (<jats:italic>p</jats:italic> &lt; 0.0001), compared to normal pregnancy: 36(14/81) μg/mL, 25(19/40) μg/mL, and 155(132/219) μg/mL, respectively; median (interquartile ranges). Early‐onset FGR male foetuses had higher HbF compared with the normal males: 0.710(0.433/0.857) mg/mL; (<jats:italic>p</jats:italic> &lt; 0.001); 0.099(0.043/0.246) mg/mL, respectively; median (interquartile ranges). In early‐onset FGR, ratios of mid‐cerebral artery and umbilical artery pulsatility indices correlated positively with heme‐scavenger levels (hemopexin and a heme‐handling composite measure: <jats:italic>p</jats:italic> &lt; 0.05, <jats:italic>r</jats:italic> = 0.672; and <jats:italic>p</jats:italic> &lt; 0.01, <jats:italic>r</jats:italic> = 0.620; respectively), indicating lower levels are associated with cerebral vascular redistribution. These heme handling measures also positively correlated with gestational age at delivery (<jats:italic>r</jats:italic> = 0.713 and <jats:italic>r</jats:italic> = 0.642, respectively, <jats:italic>p</jats:italic> &lt; 0.01, both) and birthweight (<jats:italic>r</jats:italic> = 0.742, <jats:italic>p</jats:italic> &lt; 0.001; and <jats:italic>r</jats:italic> = 0.523, <jats:italic>p</jats:italic> &lt; 0.05; respectively).ConclusionOverproduction of fHbF and an inadequate heme defence may contribute to foetal distress and poor umbilical arterial Dopplers in early onset FGR due to elevated placental vascular resistance and vascular inflammation.","PeriodicalId":8984,"journal":{"name":"BJOG: An International Journal of Obstetrics & Gynaecology","volume":"49 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-02-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143451587","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Understanding of Dietary Impacts on Miscarriage Risk","authors":"Yumei Zhong, Shanshan Liu, Xiaofeng Lv","doi":"10.1111/1471-0528.18112","DOIUrl":"https://doi.org/10.1111/1471-0528.18112","url":null,"abstract":"","PeriodicalId":8984,"journal":{"name":"BJOG: An International Journal of Obstetrics & Gynaecology","volume":"33 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-02-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143451586","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Re: Revisiting the Surgical Strategy in BRCA1/2 Carriers: Safety, Feasibility and Generalisability","authors":"Haojie Cai, Shanshan Cheng, Yu Wang","doi":"10.1111/1471-0528.18115","DOIUrl":"https://doi.org/10.1111/1471-0528.18115","url":null,"abstract":"","PeriodicalId":8984,"journal":{"name":"BJOG: An International Journal of Obstetrics & Gynaecology","volume":"81 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-02-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143451588","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Influence of Hormonal Contraceptive Usage on Risk of Endometriosis","authors":"Su-Mei Niu, De-Xiu Kong, Can Li, Fang Li, Lei Lei","doi":"10.1111/1471-0528.18086","DOIUrl":"https://doi.org/10.1111/1471-0528.18086","url":null,"abstract":"Click on the article title to read more.","PeriodicalId":8984,"journal":{"name":"BJOG: An International Journal of Obstetrics & Gynaecology","volume":"121 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-01-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143056614","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Joint Effects of Maternal Comorbidity and Neighbourhood Income Mobility on the Ensuing Risk of Severe Maternal Morbidity","authors":"Jennifer A. Jairam, Eyal Cohen, Christina Diong, Hilary K. Brown, Jun Guan, Howard Berger, Joel G. Ray","doi":"10.1111/1471-0528.18078","DOIUrl":"https://doi.org/10.1111/1471-0528.18078","url":null,"abstract":"<h2> Conflicts of Interest</h2>\u0000<p>The authors declare no conflicts of interest.</p>","PeriodicalId":8984,"journal":{"name":"BJOG: An International Journal of Obstetrics & Gynaecology","volume":"57 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-01-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142991564","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Refining Global Analysis of Female Breast and Gynaecologic Cancers: Suggestions for Enhanced Methodology and Data Update","authors":"Haojie Cai, Shanshan Cheng, Yu Wang","doi":"10.1111/1471-0528.18071","DOIUrl":"https://doi.org/10.1111/1471-0528.18071","url":null,"abstract":"Click on the article title to read more.","PeriodicalId":8984,"journal":{"name":"BJOG: An International Journal of Obstetrics & Gynaecology","volume":"6 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-01-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142967908","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Urgent Need to Address Perinatal Mental Health After Stillbirth in Low- and Middle-Income Countries","authors":"Hsia-Chun Lai, Lien-Chung Wei","doi":"10.1111/1471-0528.18060","DOIUrl":"https://doi.org/10.1111/1471-0528.18060","url":null,"abstract":"Click on the article title to read more.","PeriodicalId":8984,"journal":{"name":"BJOG: An International Journal of Obstetrics & Gynaecology","volume":"13 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-01-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142935092","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Representativeness of Study Population: A Critical Consideration for Applying Gestational Age Estimation Models","authors":"Zhenjiao Liang, Xiu Qin, Dongna Wang","doi":"10.1111/1471-0528.18059","DOIUrl":"https://doi.org/10.1111/1471-0528.18059","url":null,"abstract":"Click on the article title to read more.","PeriodicalId":8984,"journal":{"name":"BJOG: An International Journal of Obstetrics & Gynaecology","volume":"96 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-01-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142929536","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Finding the Balance: Can We Optimise Episiotomy Practices to Reduce OASIS?","authors":"Binglin Li, Yueqi Feng, Ruijuan Chen","doi":"10.1111/1471-0528.18057","DOIUrl":"https://doi.org/10.1111/1471-0528.18057","url":null,"abstract":"Click on the article title to read more.","PeriodicalId":8984,"journal":{"name":"BJOG: An International Journal of Obstetrics & Gynaecology","volume":"83 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-01-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142929529","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}