BJOG: An International Journal of Obstetrics & Gynaecology最新文献_第7页

Neonatal Outcomes Following Exposure to Different Betamethasone Formulations 暴露于不同倍他米松制剂后的新生儿结局

BJOG: An International Journal of Obstetrics & Gynaecology Pub Date : 2026-02-17 DOI: 10.1111/1471-0528.70193

Line Kolding, Işık Cem Özok, Tine Brink Henriksen, Sarah Stock, Lars Henning Pedersen

引用次数: 0

Hormone Therapy Timing and Chronic Disease Incidence in Primary Ovarian Insufficiency: A National Cohort Study 原发性卵巢功能不全的激素治疗时机和慢性疾病发病率：一项国家队列研究

BJOG: An International Journal of Obstetrics & Gynaecology Pub Date : 2026-02-11 DOI: 10.1111/1471-0528.70179

Hyun Joo Lee, Eun Hee Yu, Sul Lee, Seung Chul Kim, Jong Kil Joo

{"title":"Hormone Therapy Timing and Chronic Disease Incidence in Primary Ovarian Insufficiency: A National Cohort Study","authors":"Hyun Joo Lee, Eun Hee Yu, Sul Lee, Seung Chul Kim, Jong Kil Joo","doi":"10.1111/1471-0528.70179","DOIUrl":"https://doi.org/10.1111/1471-0528.70179","url":null,"abstract":"Objective To estimate hormone therapy (HT) use among women with primary ovarian insufficiency (POI) and to explore whether HT initiation timing is associated with differential long‐term health outcomes. Design Retrospective cohort study. Setting Population‐based using the South Korean National Health Insurance Service database. Population 105 830 South Korean women from 2005 and 2015. Methods Women with POI with ICD‐10 code E283 in the database were compared to a 1:4 propensity score‐based matching controls. Main Outcome Measures Incidence rate ratios (IRRs) and 95% confidence intervals (CIs) for major chronic diseases. Results The study compared 21 166 women with POI and 84 664 controls. POI was associated with higher risks of major chronic diseases, including thyroid disease, metabolic disorders, cardiovascular disease and osteoporosis. Within the POI cohort, HT exposure was associated with lower risks of type 2 diabetes mellitus (T2DM) (IRR 0.82, 95% CI 0.76–0.88) and dyslipidaemia (IRR 0.87, 95% CI 0.84–0.91). In the landmark analysis, on‐time HT initiation within 1 year was associated with lower risks of thyroid disease (IRR 0.69, 95% CI 0.62–0.76), T2DM (IRR 0.77, 95% CI 0.64–0.93) and dyslipidaemia (IRR 0.71, 95% CI 0.65–0.78) compared with delayed initiation. Conclusions The current study suggests that an on‐time HT initiation strategy within 1 year of POI diagnosis is associated with more favourable long‐term cardio metabolic outcomes, supporting the clinical importance of early management in POI.","PeriodicalId":8984,"journal":{"name":"BJOG: An International Journal of Obstetrics & Gynaecology","volume":"9 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-02-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146153564","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Modern Management of the Menopause: Are We Measuring What Matters? 更年期的现代管理：我们在衡量什么是重要的吗？

BJOG: An International Journal of Obstetrics & Gynaecology Pub Date : 2026-02-08 DOI: 10.1111/1471-0528.70175

Joscelyn Gan, Michelle Steeper, Tim Hillard, Monica Christmas, Jan Shifren, Nick Panay, Martha Hickey, Sarah Lensen

引用次数: 0

Scenario‐Based Guidance for International Growth Standards ( GIGS ): For Whom, When, and How to Apply the INTERGROWTH ‐21st and WHO Child Growth Standards 基于情景的国际生长标准指南（GIGS）：为谁，何时以及如何应用INTERGROWTH - 21和WHO儿童生长标准

BJOG: An International Journal of Obstetrics & Gynaecology Pub Date : 2026-02-02 DOI: 10.1111/1471-0528.70159

Eric O. Ohuma, Simon R. Parker, Sara Strout, Bancy Ngatia, Linda Vesel

{"title":"Scenario‐Based Guidance for International Growth Standards ( GIGS ): For Whom, When, and How to Apply the INTERGROWTH ‐21st and WHO Child Growth Standards","authors":"Eric O. Ohuma, Simon R. Parker, Sara Strout, Bancy Ngatia, Linda Vesel","doi":"10.1111/1471-0528.70159","DOIUrl":"https://doi.org/10.1111/1471-0528.70159","url":null,"abstract":"Objective To demonstrate when, for whom, and how to apply the INTERGROWTH−21st (IG‐21st) and WHO Child Growth Standards (WHO GS) using a scenario‐based approach with illustrations utilising a sub‐set of data from a multi‐country low birthweight infant prospective cohort. Design Scenario‐based methodological study illustrating application of existing international growth standards. Setting Global; applicable across public health, clinical, research, and epidemiological contexts where child growth monitoring is key. Population or Sample Neonates and children under 5 years. Methods Scenario‐based analyses were illustrated using a sub‐set of data from the Low birthweight Infant Feeding Exploration (LIFE) study. Weight‐for‐age z‐scores (WAZ) were computed and compared across two existing international growth standards for illustration. Main Outcome Measures Differences in infant growth assessment outcomes when applying WHO GS and IG‐21st, including effects of gestational age correction, are demonstrated through WAZ trajectories and classification differences across preterm and term infants. Results Scenario‐based analyses showed that applying growth standards inappropriately can substantially misclassify infant growth. The GIGS‐recommended approach, using IG‐21st at birth and for preterm growth, and WHO GS for term and later postnatal growth, provides consistent and accurate assessment. Conclusion The scenario‐based analysis presented in this paper illustrates how growth assessment outcomes can vary depending on the standard used, highlighting the importance of selecting the appropriate growth chart based on gestational age or age at measurement and targeted population. This guidance promotes standardised application of existing international growth standards in research and programmatic settings to facilitate resource allocation and tracking towards global nutrition targets.","PeriodicalId":8984,"journal":{"name":"BJOG: An International Journal of Obstetrics & Gynaecology","volume":"40 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-02-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146101440","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Refining the Prediction Model for Adverse Outcomes in Dichorionic Twin Pregnancies. 改进双绒毛膜双胎妊娠不良结局的预测模型。

BJOG: An International Journal of Obstetrics & Gynaecology Pub Date : 2026-01-29 DOI: 10.1111/1471-0528.70165

Wang Yi,Zongyu Yang,Songjie Liao

引用次数: 0

Factors Associated With Hormone Replacement Therapy Use: A Systematic Review and Meta-Analysis. 与激素替代疗法使用相关的因素：系统回顾和荟萃分析。

BJOG: An International Journal of Obstetrics & Gynaecology Pub Date : 2026-01-22 DOI: 10.1111/1471-0528.70160

Wema Meranda Mtika,Deborah Allen,Eve Tranter,Grace Glover,Janice Hoang,Sarah Hillman,Carol Coupland,Julia Hippisley-Cox,Lynn Tatnell,Jennifer A Hirst

{"title":"Factors Associated With Hormone Replacement Therapy Use: A Systematic Review and Meta-Analysis.","authors":"Wema Meranda Mtika,Deborah Allen,Eve Tranter,Grace Glover,Janice Hoang,Sarah Hillman,Carol Coupland,Julia Hippisley-Cox,Lynn Tatnell,Jennifer A Hirst","doi":"10.1111/1471-0528.70160","DOIUrl":"https://doi.org/10.1111/1471-0528.70160","url":null,"abstract":"OBJECTIVETo identify factors associated with HRT uptake among women.DESIGNA systematic review and meta-analysis to identify factors associated with HRT uptake.SETTINGRetrospective and prospective cohort studies, case-control studies and cross-sectional studies from any country and in any language.POPULATIONThe study population was women aged 40-60 years old.METHODSWe searched Medline, Embase, CINAHL and Cochrane databases to identify studies reporting associations between demographic, behavioural or health-related factors and HRT uptake. Studies were selected if they reported numbers or odds ratios of the factors and HRT uptake. Studies were combined for meta-analysis, reporting odds ratios and 95% confidence intervals. Quality assessment was performed to quantify the risk of bias.MAIN OUTCOME MEASURESHRT uptake, defined as 'ever' versus 'never' users.RESULTS5124 papers were identified for title and abstract screening; 136 full texts were screened; 53 were included in meta-analyses. HRT uptake was 53% lower in Black (OR 0.47, 0.30-0.73) compared to White women. Diabetes, obesity and history of stroke or venous thromboembolism were associated with lower HRT uptake (OR 0.71, 0.59-0.85; 0.67, 0.56-0.81; 0.75, 0.63-0.89; 0.78, 0.74-0.0.83 respectively). Osteoporosis and depression were associated with higher HRT uptake (OR 1.64, 1.10-2.45 and 1.69, 1.17-2.43, respectively).CONCLUSIONSThere are differences in HRT uptake by ethnicity and health characteristics. However, findings are not generalisable globally. Our results could aid healthcare professionals and policymakers to address the gaps in HRT uptake and promote healthcare equity.","PeriodicalId":8984,"journal":{"name":"BJOG: An International Journal of Obstetrics & Gynaecology","volume":"47 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-01-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146021519","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Measuring Race Equality in the Obstetrics and Gynaecology Workforce and Training: A Delphi Core Outcome Set Study. 衡量种族平等的妇产科劳动力和培训：德尔菲核心结果集研究。

BJOG: An International Journal of Obstetrics & Gynaecology Pub Date : 2026-01-22 DOI: 10.1111/1471-0528.70163

Nicola Adanna Okeahialam,Jameela Sheikh,John Allotey,Farah Siddiqui,Ranee Thakar,Shakila Thangaratinam

{"title":"Measuring Race Equality in the Obstetrics and Gynaecology Workforce and Training: A Delphi Core Outcome Set Study.","authors":"Nicola Adanna Okeahialam,Jameela Sheikh,John Allotey,Farah Siddiqui,Ranee Thakar,Shakila Thangaratinam","doi":"10.1111/1471-0528.70163","DOIUrl":"https://doi.org/10.1111/1471-0528.70163","url":null,"abstract":"OBJECTIVETo develop a core outcome set (COS) to standardise measurement and reporting of race equality within the obstetrics and gynaecology workforce and training.DESIGNMulti-stakeholder Delphi survey.SETTINGObstetrics and gynaecology care in secondary and tertiary hospitals in the UK.POPULATIONClinicians, trainees, service managers, researchers, midwives, and service design representatives from healthcare organisations, professional bodies, and charities relevant to maternity services and medical education.METHODSRelevant outcomes from the literature were identified and grouped thematically. We undertook a two-round Delphi survey, prioritising outcomes by scoring on a nine-point Likert scale (1 = limited importance, 9 = critical). Consensus was predefined as a median score ≥ 8 and IQR ≤ 2. The final core outcome set was finalised by consensus and consultation.MAIN OUTCOME MEASURESA minimum set of core outcomes for assessing race equality within obstetrics and gynaecology workforce and training.RESULTSThe survey was completed by 45 stakeholders. Ninety-two outcomes were identified, condensed to 41 and grouped across 11 themes. Thirteen were chosen in the first round, five in the second, 10 additional were proposed, and after consensus, 18 were selected to be included as core outcomes. Fifteen participants attended the final consultation meeting. Outcome themes included workforce representation, pay, postgraduate training, disciplinary processes, career progression, and harassment and bullying.CONCLUSIONSThis is the first COS developed to measure race equality in the obstetrics and gynaecology workforce. Standardised reporting of these outcomes will enable benchmarking across organisations, inform targeted interventions, and support the development of a more equitable and inclusive workforce.","PeriodicalId":8984,"journal":{"name":"BJOG: An International Journal of Obstetrics & Gynaecology","volume":"95 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-01-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146021511","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Risk of Adverse Birth Outcomes Among Twin Pregnancies After Influenza and Pertussis Vaccinations During Pregnancy: A Data Linkage Study. 妊娠期间接种流感和百日咳疫苗后双胎妊娠不良出生结局的风险：一项数据链接研究。

BJOG: An International Journal of Obstetrics & Gynaecology Pub Date : 2026-01-18 DOI: 10.1111/1471-0528.70156

Kahlee Boyle,Sarah Graham,Michael Binks,Lisa McHugh

{"title":"The Risk of Adverse Birth Outcomes Among Twin Pregnancies After Influenza and Pertussis Vaccinations During Pregnancy: A Data Linkage Study.","authors":"Kahlee Boyle,Sarah Graham,Michael Binks,Lisa McHugh","doi":"10.1111/1471-0528.70156","DOIUrl":"https://doi.org/10.1111/1471-0528.70156","url":null,"abstract":"OBJECTIVETo compare risks of adverse birth outcomes between maternally vaccinated and unvaccinated twin pregnancies.DESIGNMulti-jurisdictional data linkage cohort study.SETTINGAll registered births in Queensland (Qld) and Northern Territory (NT), Australia between 1 January 2012 and 31 December 2017.POPULATIONTwin pregnancies with infants born ≥ 20 weeks gestation and weighing ≥ 400 g.METHODSWe used Cox proportional-hazard models to calculate risk, with maternal vaccination status as the time-varying exposure, and national birthweight percentile charts specific for Australian-born twins to accurately reflect risk among small for gestational age (SGA) infants.MAIN OUTCOME MEASURESAdverse birth outcomes including preterm birth, stillbirth and SGA infants.RESULTSAmong our cohort of n = 11 435 infants, there was no statistically significant increased risk of preterm births, stillbirths or SGA infants between women who received a maternal influenza or pertussis vaccination and unvaccinated women. We observed a non-significant lower risk of SGA infants among pertussis vaccinated Qld (aHR 0.85, 95% CI 0.70-1.03) and NT women (aHR 0.50, 95% CI 0.17-1.44), and a lower risk of preterm infants among influenza vaccinated Qld women (aHR 0.93, 95% CI 0.84-1.03) and pertussis vaccinated NT women (aHR 0.78, 95% CI 0.44-1.38).CONCLUSIONMaternal influenza and pertussis vaccinations did not increase the risk of preterm birth, stillbirth or SGA infants among twin pregnancies. These novel and important findings alleviate safety concerns for a cohort that carries a higher baseline risk of adverse birth outcomes compared to singleton pregnancies.","PeriodicalId":8984,"journal":{"name":"BJOG: An International Journal of Obstetrics & Gynaecology","volume":"47 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-01-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145994948","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Interpreting ERAP2 as an Ageing-Derived Biomarker for Premature Ovarian Insufficiency. 解释ERAP2作为卵巢早衰的衰老衍生生物标志物。

BJOG: An International Journal of Obstetrics & Gynaecology Pub Date : 2026-01-12 DOI: 10.1111/1471-0528.70148

Xiaowen Feng,Yidan Jin,Ruijin Wu

引用次数: 0

Supporting Physiological Labour and Childbirth in Modern Maternity Services. 现代妇产服务对生理分娩的支持。

BJOG: An International Journal of Obstetrics & Gynaecology Pub Date : 2026-01-12 DOI: 10.1111/1471-0528.70152

Soo Downe

引用次数: 0