BJOG: An International Journal of Obstetrics & Gynaecology最新文献

{"title":"Salpingectomy With Delayed Oophorectomy Versus Salpingo‐Oophorectomy in BRCA1/2 Carriers: Three‐Year Outcomes of a Prospective Preference Trial","authors":"Majke H. D. Van Bommel, Miranda P. Steenbeek, Joanna Inthout, Tessa Van Garderen, Marline G. Harmsen, Marieke Arts‐De Jong, Angela H. E. M. Maas, Judith B. Prins, Johan Bulten, Helena C. Van Doorn, Marian J. E. Mourits, Rachel Tros, Ronald P. Zweemer, Katja N. Gaarenstroom, Brigitte F. M. Slangen, Monique M. A. Brood‐Van Zanten, M. Caroline Vos, Jurgen M. J. Piek, Luc R. C. W. van Lonkhuijzen, Mirjam J. A. Apperloo, Sjors F. P. J. Coppus, Nicoline Hoogerbrugge, Rosella P. M. G. Hermens, Joanne A. De Hullu","doi":"10.1111/1471-0528.18075","DOIUrl":"https://doi.org/10.1111/1471-0528.18075","url":null,"abstract":"ObjectiveTo compare menopause‐related quality of life (QoL) after risk‐reducing salpingectomy (RRS) versus risk‐reducing salpingo‐oophorectomy (RRSO) until 3 years of post‐surgery.DesignA prospective study (TUBA study) with treatment allocation based on patients' preference. Data were collected pre‐surgery and at 3 months, 1 and 3 years of post‐surgery.SettingMulticentre prospective preference trial in thirteen hospitals in the Netherlands.Population<jats:italic>BRCA1/2</jats:italic> pathogenic variant (PV) carriers aged 25–40 (<jats:italic>BRCA1</jats:italic>) or 25–45 (<jats:italic>BRCA2</jats:italic>), who were premenopausal, without a future child wish and without current (treatment for) malignancy.MethodsTreatment allocation was based on patients' preference: either RRS from the age of 25 years with delayed oophorectomy at the maximum age of 45 (<jats:italic>BRCA1</jats:italic>) or 50 (<jats:italic>BRCA2</jats:italic>), or RRSO between the ages of 35–40 (<jats:italic>BRCA1</jats:italic>) or 40–45 (<jats:italic>BRCA2</jats:italic>). After RRSO, hormone replacement therapy (HRT) was recommended, if not contraindicated. Primarily, menopause‐related QoL as measured with the Greene Climacteric Scale (GCS) was compared between the RRS and RRSO without HRT group. Secondarily, GSC‐scores of the RRS group were compared with the scores of the RRSO with HRT after surgery group. A higher GSC‐score reflects more climacteric symptoms.ResultsUntil April 2023, 410 participants had undergone RRS and 160 RRSO. The <jats:italic>BRCA1/BRCA2</jats:italic> proportions were 51.4%/48.6%. The mean age at surgery (SD) was 37.9 (3.5) years. Participants 3 years after RRSO without HRT had a 4.3 (95% CI 2.1–6.5; <jats:italic>p</jats:italic> &lt; 0.001) point higher increase in GCS‐score from baseline compared to those after RRS, while the difference was 7.9 (95% CI 5.9–9.8) and 8.5 (95% CI 6.5–10.5) points at 3 and 12 months, respectively. Among participants with HRT after surgery, the RRSO group had a 2.4 (95% CI 0.8–3.9; <jats:italic>p =</jats:italic> 0.002) point higher increase in GCS‐score from baseline compared to the RRS group.ConclusionsIn this multicentre preference trial, menopause‐related QoL was better after RRS than after RRSO, even with HRT after RRSO. Differences between arms were most pronounced until one‐year post‐surgery.","PeriodicalId":8984,"journal":{"name":"BJOG: An International Journal of Obstetrics & Gynaecology","volume":"37 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-01-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142987604","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Intrauterine Contraction Monitoring in Chorioamnionitis: A Secondary, Blinded Analysis of a Randomised Controlled Trial Cohort","authors":"Milla Juhantalo, Tuija Hautakangas, Outi Palomäki, Jukka Uotila","doi":"10.1111/1471-0528.18076","DOIUrl":"https://doi.org/10.1111/1471-0528.18076","url":null,"abstract":"To study the effects of chorioamnionitis on uterine activity and to investigate associations between external and intrauterine monitoring methods and neonatal outcomes.","PeriodicalId":8984,"journal":{"name":"BJOG: An International Journal of Obstetrics & Gynaecology","volume":"80 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-01-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142987148","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Predicting Preterm Birth: An Evolving Landscape","authors":"Caroline Fox, Andrew Shennan","doi":"10.1111/1471-0528.18067","DOIUrl":"https://doi.org/10.1111/1471-0528.18067","url":null,"abstract":"","PeriodicalId":8984,"journal":{"name":"BJOG: An International Journal of Obstetrics & Gynaecology","volume":"34 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-01-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142974779","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Refining Global Analysis of Female Breast and Gynaecologic Cancers: Suggestions for Enhanced Methodology and Data Update","authors":"Haojie Cai, Shanshan Cheng, Yu Wang","doi":"10.1111/1471-0528.18071","DOIUrl":"https://doi.org/10.1111/1471-0528.18071","url":null,"abstract":"Click on the article title to read more.","PeriodicalId":8984,"journal":{"name":"BJOG: An International Journal of Obstetrics & Gynaecology","volume":"6 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-01-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142967908","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Consensus on Symptom Selection for Endometriosis Questionnaires: A Modified e-Delphi Study","authors":"Tong Zhu, Henrik Marschall, Karina E. Hansen, Andrew W. Horne, Lucky Saraswat, Krina T. Zondervan, Stacey A. Missmer, Lone Hummelshoj, Atilla Bokor, Camilla S. Østrup, Anna Melgaard, Dorte Rytter","doi":"10.1111/1471-0528.18066","DOIUrl":"https://doi.org/10.1111/1471-0528.18066","url":null,"abstract":"To build consensus on most important symptoms and related consequences for use in questionnaires to characterise individuals with suspected and confirmed endometriosis in the general population.","PeriodicalId":8984,"journal":{"name":"BJOG: An International Journal of Obstetrics & Gynaecology","volume":"16 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-01-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142967909","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"L-Arginine and L-Citrulline for Prevention and Treatment of Pre-Eclampsia: A Systematic Review and Meta-Analysis","authors":"Maureen Makama, Annie R. A. McDougall, Jenny Cao, Kate Mills, Phi-Yen Nguyen, Roxanne Hastie, Anne Ammerdorffer, A. Metin Gülmezoglu, Joshua P. Vogel","doi":"10.1111/1471-0528.18070","DOIUrl":"https://doi.org/10.1111/1471-0528.18070","url":null,"abstract":"Evidence suggests L-arginine may be effective at reducing pre-eclampsia and related outcomes. However, whether L-arginine can prevent or only treat pre-eclampsia, and thus the target population and timing of initiation, remains unknown.","PeriodicalId":8984,"journal":{"name":"BJOG: An International Journal of Obstetrics & Gynaecology","volume":"9 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-01-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142967907","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prolonged Ovarian Stimulation Does Not Worsen Neonatal Outcomes After Fresh Embryo Transfers","authors":"Jing Wu, Ying Ju, Jie Dong, Hengde Zhang, Xifeng Xiao, Xiaohong Wang","doi":"10.1111/1471-0528.18062","DOIUrl":"https://doi.org/10.1111/1471-0528.18062","url":null,"abstract":"To investigate the relationship between prolonged ovarian stimulation and neonatal outcomes after autologous fresh embryo transfer (fET).","PeriodicalId":8984,"journal":{"name":"BJOG: An International Journal of Obstetrics & Gynaecology","volume":"38 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142940075","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Improving Maternal and Infant Health Outcomes: Strengthening Research and Interventions for Cannabis Use Disorder During Pregnancy","authors":"Jiahua Peng, Yi Shi, Mei Yang","doi":"10.1111/1471-0528.18072","DOIUrl":"https://doi.org/10.1111/1471-0528.18072","url":null,"abstract":"Click on the article title to read more.","PeriodicalId":8984,"journal":{"name":"BJOG: An International Journal of Obstetrics & Gynaecology","volume":"20 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142940074","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Digital Foetal Scalp Stimulation Versus Foetal Blood Sampling to Assess Foetal Well-Being in Labour: A Multicentre Randomised Controlled Trial","authors":"Sahr Yambasu, Fiona Boland, Keelin O'Donoghue, Colleen Curran, Yulia Shahabuddin, Amanda Cotter, Geraldine Gaffney, Declan Devane, Eleanor J. Molloy, Deirdre J. Murphy","doi":"10.1111/1471-0528.18068","DOIUrl":"https://doi.org/10.1111/1471-0528.18068","url":null,"abstract":"To establish whether digital foetal scalp stimulation (dFSS) performs better than foetal blood sampling (FBS) in terms of reducing the rate of caesarean section (CS) in labour, without adversely affecting perinatal outcomes.","PeriodicalId":8984,"journal":{"name":"BJOG: An International Journal of Obstetrics & Gynaecology","volume":"15 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-01-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142937735","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Is There a Diminishing Benefit With Increasing Operative Time of Minimally Invasive Sacrocolpopexy? A Retrospective Analysis","authors":"Maura A. Schlussel, Stephen P. Rhodes, Susan D. Wherley, C. Emi Bretschneider, Ankita Gupta, David Sheyn","doi":"10.1111/1471-0528.18069","DOIUrl":"https://doi.org/10.1111/1471-0528.18069","url":null,"abstract":"To determine whether there is an operative time threshold beyond which minimally invasive sacrocolpopexy (MI-SCP) is less beneficial than abdominal sacrocolpopexy (ASCP).","PeriodicalId":8984,"journal":{"name":"BJOG: An International Journal of Obstetrics & Gynaecology","volume":"19 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-01-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142937701","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}