BMC Infectious Diseases最新文献

{"title":"Drug resistance profile of Mycobacterium tuberculosis complex isolated from pulmonary tuberculosis patients and their household contacts in central Ethiopia.","authors":"Getachew Seid, Ayinalem Alemu, Getu Diriba, Betselot Zerihun, Gemechu Tadesse, Solomon H Mariam, Balako Gumi","doi":"10.1186/s12879-025-11220-x","DOIUrl":"10.1186/s12879-025-11220-x","url":null,"abstract":"<p><strong>Background: </strong>There is a gap between tuberculosis (TB) infection and the onset of clinical TB disease, which makes identifying TB transmission dynamics a prominent challenge. Different reports were made on the concordance of drug-resistance profiles between the household contact and the purported index case. This study investigated the drug-resistance pattern concordance of the index-household contact pair in central Ethiopia.</p><p><strong>Method: </strong>A laboratory-based cross-sectional study was conducted on Mycobacterium tuberculosis isolates identified from bacteriologically confirmed pulmonary TB patients and their household contacts (HHCs) in central Ethiopia from January to December 2023. Sputum specimens were collected from index cases and presumptive HHCs and examined using the Xpert Ultra assay, Xpert XDR assay, and Mycobacterium tuberculosis culture. Descriptive statistics were used to summarize the data.</p><p><strong>Result: </strong>Among 902 TB symptoms screened HHCs of 303 index cases, 20.17% (182/902) had Presumptive TB, and 7.14% (13/182) developed active tuberculosis. In index cases, 23.52% (64 /272) showed resistance to at least one of the five first-line anti-TB drugs. The prevalence of mono-resistant to STR, INH, RIF, and PZA was: 2.20% (6 /272), 2.20% (6/272), 6.25% (17/272), and 1.47% (4/272), respectively. Any first-line anti-TB drug resistance was higher among relapse cases than new cases, at 41.67% (10/24) and 21.77% (54/248), respectively. Among the RR/MDR-TB cases tested with the Xpert MTB/XDR assay, 56.81% (25/44) cases showed resistance to INH. Among these 25 INH resistance samples, 5 had no melting point on the wild ahpc gene as well as on the ahpc gene mutant. In HHCs with positive cultures, 23.07% (3/13) displayed resistance to any first-line anti-TB medication. Only 69.23% (9/13) of HHCs had isolates that aligned with the pDST pattern of the index case for all five first-line anti-TB drugs.</p><p><strong>Conclusion: </strong>Nearly one-third of the household contacts have discordant drug-resistance profiles from the index patients. This study offers compelling proof that it is not advisable to treat close contacts without DST results based on the DST results of the supposed source case. The low drug resistance rate to new oral second-line drugs in this study did not guarantee the absence of resistance to each drug.</p>","PeriodicalId":8981,"journal":{"name":"BMC Infectious Diseases","volume":"25 1","pages":"806"},"PeriodicalIF":3.4,"publicationDate":"2025-06-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12181880/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144336304","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"STI point-of care tests: a call for quality-assured evaluation, implementation, innovation, and investment in future technologies.","authors":"David A Lewis, Maria M Lleo, Francis Ndowa, Tariq Sadiq, Teodora Wi","doi":"10.1186/s12879-025-11103-1","DOIUrl":"10.1186/s12879-025-11103-1","url":null,"abstract":"","PeriodicalId":8981,"journal":{"name":"BMC Infectious Diseases","volume":"25 1","pages":"805"},"PeriodicalIF":3.4,"publicationDate":"2025-06-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12175335/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144315860","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Multidrug-resistant Pseudomonas aeruginosa in immunocompromised cancer patients: epidemiology, antimicrobial resistance, and virulence factors.","authors":"Asmaa Abdulhak, Hamdallah H Zedan, Hadir A El-Mahallawy, Ahmed A Sayed, Hend O Mohamed, Mai M Zafer","doi":"10.1186/s12879-025-11182-0","DOIUrl":"10.1186/s12879-025-11182-0","url":null,"abstract":"","PeriodicalId":8981,"journal":{"name":"BMC Infectious Diseases","volume":"25 1","pages":"804"},"PeriodicalIF":3.4,"publicationDate":"2025-06-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12153119/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144274186","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparative genomics of Acinetobacter baumannii from Egyptian healthcare settings reveals high-risk clones and resistance gene mobilization.","authors":"Salma Salem, Dina Osama, Nehal Adel Abdelsalam, Ahmed H Shata, Shaimaa F Mouftah, Mohamed Elhadidy","doi":"10.1186/s12879-025-11185-x","DOIUrl":"10.1186/s12879-025-11185-x","url":null,"abstract":"<p><strong>Background: </strong>Acinetobacter baumannii (A. baumannii) has emerged as a major public health threat in low- and middle-income countries (LMICs), particularly in Egypt, due to its remarkable ability to acquire and transfer resistance genes, as highlighted in the WHO bacterial Priority Pathogens List 2024 classification. This pilot study aimed to characterize 18 A. baumannii isolates from Egyptian healthcare settings, focusing on clonal lineages, antibiotic resistance determinants, horizontal gene transfer potential, and the presence of virulence factors and chromosomal mutations.</p><p><strong>Methods: </strong>Antimicrobial susceptibility testing was performed to determine resistance profiles using minimum inhibitory concentrations. Whole-genome sequencing was used to identify β-lactamase, carbapenemase, and other antibiotic resistance genes (ARGs), as well as mobile genetic elements (MGEs). Clonal relationships among isolates were assessed via core genome multilocus sequence typing (cgMLST).</p><p><strong>Results: </strong>Phenotypic analysis revealed that 72% of the isolates were extensively drug-resistant (XDR), exhibiting resistance to all tested antibiotics except colistin. Clonal diversity analysis identified 11 Oxford sequence types (STs), including two novel STs (ST3309^OXF and ST3321^OXF), and six international clonal (IC) groups, with IC2 being the most prevalent. Additionally, eight Pasteur STs were detected, with ST570^PAS being the most frequent. The cgMLST analysis showed that two Egyptian ST570^PAS isolates clustered with a strain from Saudi Arabia, suggesting potential regional transmission. Genomic analysis revealed the widespread dissemination of ARGs via MGEs, particularly rep plasmids and insertion sequence elements, which contributed significantly to genomic diversity and antibiotic resistance.</p><p><strong>Conclusions: </strong>This pilot study highlights the clonal diversity of A. baumannii in Egypt and underscores the critical role of MGEs in the spread of resistance genes. Targeted genomic surveillance and infection control are essential to curb the spread of high-risk resistant A. baumannii clones in Egyptian clinical settings.</p>","PeriodicalId":8981,"journal":{"name":"BMC Infectious Diseases","volume":"25 1","pages":"803"},"PeriodicalIF":3.4,"publicationDate":"2025-06-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12153194/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144274185","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Integrating machine learning and spatial clustering for malaria case prediction in Brazil's Legal Amazon.","authors":"Kayo Henrique de Carvalho Monteiro, Élisson da Silva Rocha, Luis Augusto Morais, Elton Gino Santos, Sebastião Rogerio da S Neto, Vanderson Sampaio, Patricia Takako Endo","doi":"10.1186/s12879-025-11193-x","DOIUrl":"10.1186/s12879-025-11193-x","url":null,"abstract":"<p><p>Malaria remains a major global health challenge, particularly in Brazil's Legal Amazon region, where environmental and socioeconomic conditions foster favorable conditions for disease transmission. Traditional control measures have shown limited effectiveness, emphasizing the need for better predictive approaches to support timely and targeted public health interventions. This study evaluates the performance of six computational models-Long Short-Term Memory (LSTM), Gated Recurrent Units (GRU), Support Vector Regression (SVR), Random Forest (RF), eXtreme Gradient Boosting (XGBoost), and Autoregressive Integrated Moving Average (ARIMA)-for forecasting weekly malaria cases across multiple states in the Legal Amazon. The results demonstrate that the RF model consistently outperformed the other models, achieving the lowest Root Mean Squared Error (RMSE) and Mean Absolute Error (MAE) values in most cases, such as in cluster 02 of the state of Acre, with RMSE of 0.00203 and MAE of 0.00133. The integration of K-means clustering further improved the model predictive accuracy by accounting for spatial heterogeneity and capturing localized transmission dynamics. This hybrid modeling approach, combining machine learning models with spatial clustering, offers a promising tool for enhancing malaria surveillance and guiding more effective public health strategies, especially for malaria control efforts in high-risk regions.</p>","PeriodicalId":8981,"journal":{"name":"BMC Infectious Diseases","volume":"25 1","pages":"802"},"PeriodicalIF":3.4,"publicationDate":"2025-06-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12147289/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144246255","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Post-treatment time to symptom resolution and associated factors in a cohort of Ugandan men with urethral discharge syndrome.","authors":"Courtney Pasco, Yisi Liu, Junyi Zhou, Ethan Gough, Annet Onzia, Rosalind Parkes-Ratanshi, Johan H Melendez, Peter Kyambadde, Yukari C Manabe, Matthew M Hamill","doi":"10.1186/s12879-025-11196-8","DOIUrl":"10.1186/s12879-025-11196-8","url":null,"abstract":"<p><strong>Introduction: </strong>Ugandan men with urethral discharge syndrome (UDS) have high burdens of curable sexually transmitted infections (STIs) and HIV. STI complaints are treated syndromically, but post-treatment symptom resolution (SR) data are lacking in this group. This study estimated the time from treatment to symptom resolution (TTR) and examined associations with sociodemographic and behavioral factors and TTR.</p><p><strong>Methods: </strong>250 men with UDS were recruited at health centers in Kampala, Uganda. Participants underwent point-of-care testing for HIV/syphilis, and urogenital samples were retrospectively analyzed for Chlamydia trachomatis (CT), Neisseria gonorrhoeae (NG), Mycoplamsa genitalium (MG), and Trichomonas vaginalis (TV) using Aptima nucleic acid amplification tests (Hologic Inc., Marlborough, MA, USA). Socio-behavioral data were collected by questionnaire. Participants received follow-up calls at 14-, and 21-days post-enrollment to assess SR, antibiotic adherence, and sexual behaviors. Differences between participants by SR at day 14 were determined by Fisher Exact test, Wilcoxon rank-sum test, Chi-squared test, and Welch's t-test as appropriate. Univariable and multivariable accelerated failure time (AFT) models were used to identify associations between participant factors and TTR.</p><p><strong>Results: </strong>Of 239 (95.6%) participants who completed day 14 follow-up surveys, 37 (16%) did not have SR by 14-days post-enrollment and treatment initiation. Median (IQR) TTR was 4.0 (3.0,6.0) days. Delayed TTR was associated with previous episodes of UDS in the prior six months (2.0 vs. 1.4, p = 0.010) and negative tests for CT/NG/MG/TV (35% vs. 15%, p = 0.004). These relationships held true when controlling for potential confounders including prior antimicrobial use, possible reinfection following sexual exposures post-enrollment, treatment non-adherence, HIV status, and other behaviors associated with increased vulnerabilities to STIs.</p><p><strong>Conclusion: </strong>Delayed TTR was associated with prior UDS episodes. Negative tests for common curable STIs were associated with delayed TTR suggesting the possible role of other infectious or non-infectious etiologies. The underlying mechanisms of delayed SR, e.g., reinfection, treatment failure, or dysregulated mucosal immunity, warrant further exploration.</p>","PeriodicalId":8981,"journal":{"name":"BMC Infectious Diseases","volume":"25 1","pages":"801"},"PeriodicalIF":3.4,"publicationDate":"2025-06-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12147313/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144246256","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A case of hepatic-splenic abscess in a non-endemic area of brucellosis: insights from complex infection with brucellosis.","authors":"Shufang Pan, Yuankai Wu, Kaixiang Zhou, Jie Gao, Jiaoling Li, Chengyuan Liu, Yutian Chong, Jianyun Zhu","doi":"10.1186/s12879-025-11206-9","DOIUrl":"10.1186/s12879-025-11206-9","url":null,"abstract":"<p><p>We present the case of a 47-year-old male patient who exhibited recurrent fever and was diagnosed with liver and splenic abscesses. Magnetic Resonance Imaging of the upper abdomen showed several hypodense lesions in the liver and spleen. A puncture of the liver abscess was performed and the sample was subjected to Next-Generation Sequencing (NGS). The results of both the liver sample and blood NGS indicated the presence of Brucella. Further examination of the liver and spleen pus suggested necrotizing purulent inflammation. Consequently, the final diagnosis confirmed the condition as brucellosis, liver abscess, and splenic abscess. Doxycycline, rifapentine, and levofloxacin were administered to treat the infection. However, the results were suboptimal. Subsequently, the patient underwent a splenectomy and open drainage of an abscess of the liver. Following the surgical intervention, the patient's symptoms improved gradually and he continued his regimen of doxycycline, rifapentine, and trimethoprim-sulfamethoxazole therapy. This triple-drug combination was maintained for a duration of up to 32 months to effectively control the infection and was ultimately discontinued after a thorough evaluation of the stable lesion. For brucellosis patients with abdominal abscesses, effective treatment requires surgical debridement and extended anti-infective therapy.</p>","PeriodicalId":8981,"journal":{"name":"BMC Infectious Diseases","volume":"25 1","pages":"798"},"PeriodicalIF":3.4,"publicationDate":"2025-06-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12142888/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144246253","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prevalence of drug-resistant Mycobacterium tuberculosis and its associated factors among tuberculosis patients attending Dilla university referral hospital, Ethiopia.","authors":"Melat Hatiya, Yared Merid, Addis Mola, Fanuel Belayneh, Musa Mohammed Ali","doi":"10.1186/s12879-025-11191-z","DOIUrl":"10.1186/s12879-025-11191-z","url":null,"abstract":"<p><strong>Background: </strong>Tuberculosis (TB) is an infectious disease caused by Mycobacterium tuberculosis (MTB) and is the second leading cause of death from contagious diseases worldwide. Ethiopia is among the 30 countries with the highest burden of TB and TB/HIV co-infection. The emergence and spread of drug-resistant TB present significant challenges to TB care and control efforts, particularly multi-drug-resistant TB, which poses a serious public health issue in low-income countries such as Ethiopia. This study aimed to determine the prevalence of drug-resistant TB and its associated factors among TB patients in Dilla University Referral Hospital (DURH).</p><p><strong>Method: </strong>A prospective cross-sectional study was conducted from March-2024 to May-2024 among 216 pulmonary TB patients attending DURH. Gene Xpert MTB/RIF Ultra and Xpert MTB/XDR assay was used to assess the pattern of drug resistance in TB. The Xpert MTB/RIF Ultra assay was used to detect rifampicin resistance, while the Xpert MTB/XDR assay was employed to identify isoniazid resistance and resistance to second-line anti-TB drugs when rifampicin resistance was detected. Data were analyzed by using the Statistical Package for Social Sciences (SPSS) version 25.</p><p><strong>Result: </strong>In this study, out of 216 confirmed MTB cases, 5 (2.3%) were identified as drug-resistant TB (DR-TB), with mono-resistance to rifampicin and isoniazid at 1.4% and 0.9%, respectively. The statistical analysis revealed a significant difference in DR-TB prevalence between those with and without a history of anti-TB treatment (p = 0.001). Notably, isoniazid mono-resistant TB was more prevalent among individuals with diabetes mellitus and those with a history of previous treatment, showing p-values of 0.018 and 0.015, respectively.</p><p><strong>Conclusion: </strong>Among the 216 confirmed TB cases, 5 cases of DR-TB were identified, accounting for 2.3%. DR-TB was more prevalent in patients with a history of anti-TB treatment, highlighting the urgent need for enhanced early detection and improved treatment monitoring. Additionally, isoniazid mono-resistant TB was notably prevalent in individuals with diabetes mellitus and prior treatment history, with p-values of 0.018 and 0.015, respectively. Targeted interventions for these high-risk groups are essential to address drug resistance in TB, enabling us to effectively tackle the emergence of drug-resistant TB at both local and national levels.</p>","PeriodicalId":8981,"journal":{"name":"BMC Infectious Diseases","volume":"25 1","pages":"797"},"PeriodicalIF":3.4,"publicationDate":"2025-06-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12142839/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144246257","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Anthropogenic influences on Rhodnius ecuadoriensis populations and nesting behaviors in sylvatic areas of southern ecuador.","authors":"Jazive Esparza-Carate, Soledad Santillán-Guayasamín, César A Yumiseva, Juan José Bustillos, Mario J Grijalva, Sereno Denis, Anita G Villacís","doi":"10.1186/s12879-025-11175-z","DOIUrl":"10.1186/s12879-025-11175-z","url":null,"abstract":"<p><strong>Background: </strong>Chagas disease, caused by the parasite Trypanosoma cruzi, remains a major public health concern. While Rhodnius ecuadoriensis, a key vector, is traditionally sylvatic, environmental disturbances have driven its adaptation to human-influenced habitats. This study explores a novel factor: how anthropogenic waste affects vector ecology by altering nest compositions. Unlike prior research, this study examines whether human-derived materials in nests influence triatomine colonization. Given rising pollution, particularly post-COVID-19, understanding its role in disease transmission is essential for developing innovative vector control strategies.</p><p><strong>Methods: </strong>Nest records were collected and analyzed in 2018, 2022, and 2023, across eight communities in Loja province, Ecuador. Nests were categorized as peridomestic if found < 30 m from a house and sylvatic if > 30 m away. The number of insects found in these nests was quantified using entomological indices. Pearson correlation analysis was applied to assess relationships between nest location and the presence of anthropogenic materials.</p><p><strong>Results: </strong>A total of 389 nests were examined, yielding 1,089 individuals of Rhodnius ecuadoriensis (including both nymphs and adults). The infestation index in peridomestic areas dramatically decreased from 33.3% in 2018 to 0% in 2022, highlighting an intriguing temporal shift that warrants further investigation. In contrast, sylvatic areas showed fluctuating infestation rates (27.5% in 2018, 16.5% in 2022, and 22.2% in 2023). The study uniquely identified a significant association between triatomine infestation and mammal nests, with 50.1% of infested nests located within mammal habitats. Notably, 35.2% of these nests contained anthropogenic materials, particularly near human-altered landscapes such as roads and paths. The weak to moderate negative correlation between the presence of anthropogenic materials and proximity to roads or rivers (r = -0.361, p = 0.039) highlights an innovative exploration of the influence of human environmental changes on vector ecology.</p><p><strong>Conclusions: </strong>This study offers a novel perspective on the dual impact of increasing pollution levels on wildlife. It highlights how anthropogenic waste not only reduces vector populations but also increases mortality rates through entanglement in waste materials. These findings underscore the urgent need for environmental education programs focused on waste management within local communities. Furthermore, the study paves the way for further research to assess the rate of T. cruzi infection in relation to environmental and anthropogenic factors, offering a critical foundation for understanding and potentially mitigating Chagas disease transmission.</p>","PeriodicalId":8981,"journal":{"name":"BMC Infectious Diseases","volume":"25 1","pages":"799"},"PeriodicalIF":3.4,"publicationDate":"2025-06-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12144819/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144246254","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Two cases of Talaromyces marneffei tracheobronchial infection in HIV-negative patients.","authors":"Xingbing Lu, Juan Chen, Shiqi Miao, Yi Xie","doi":"10.1186/s12879-025-11143-7","DOIUrl":"10.1186/s12879-025-11143-7","url":null,"abstract":"","PeriodicalId":8981,"journal":{"name":"BMC Infectious Diseases","volume":"25 1","pages":"800"},"PeriodicalIF":3.4,"publicationDate":"2025-06-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12144829/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144246258","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}