Japanese clinical medicine最新文献_第4页

Patients' perception on the nutritional therapy for diabetic nephropathy. 糖尿病肾病患者对营养治疗的认知。

Japanese clinical medicine Pub Date : 2014-04-28 eCollection Date: 2014-01-01 DOI: 10.4137/JCM.S13315

Kenichiro Shide, Yuka Takada, Asuka Nakashima, Hidemi Tsuji, Keiko Wada, Akiko Kuwabara, Kiyoshi Tanaka, Nobuya Inagaki

{"title":"Patients' perception on the nutritional therapy for diabetic nephropathy.","authors":"Kenichiro Shide, Yuka Takada, Asuka Nakashima, Hidemi Tsuji, Keiko Wada, Akiko Kuwabara, Kiyoshi Tanaka, Nobuya Inagaki","doi":"10.4137/JCM.S13315","DOIUrl":"https://doi.org/10.4137/JCM.S13315","url":null,"abstract":"Low protein diet (LPD) plays an important role in preventing the progression of diabetic nephropathy. However, it is a great burden to the patients. In this paper, we have studied the quality of life (QOL) in such patients. The study subjects were 59 patients (male 38, female 21) with type 2 diabetes. The patients were classified into tertiles based on their protein intake (g/kg BW). Scores from the diet-related QOL questionnaire were summarized by principal component analysis into four components; mental health, less burden, satisfaction and merit, and less social restriction. Higher protein intake was associated with less burden and less social restriction. In multiple regression analysis, the significant predictors for the \"less burden\" component were higher protein intake/BW and estimated glomerular filtration rate (eGFR). In summary, registered dietitians and clinicians must keep in mind that LPD is a serious burden to the patients and efforts must be made to minimize their burden in order to avoid discontinuation. ","PeriodicalId":89792,"journal":{"name":"Japanese clinical medicine","volume":"5 ","pages":"9-13"},"PeriodicalIF":0.0,"publicationDate":"2014-04-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.4137/JCM.S13315","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"32362959","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 5

Association between lung function and metabolic syndrome independent of insulin in Japanese men and women. 日本男性和女性肺功能与独立于胰岛素的代谢综合征的关系

Japanese clinical medicine Pub Date : 2014-04-24 eCollection Date: 2014-01-01 DOI: 10.4137/JCM.S13564

Yayoi Yamamoto, Junko Oya, Tomoko Nakagami, Yasuko Uchigata

{"title":"Association between lung function and metabolic syndrome independent of insulin in Japanese men and women.","authors":"Yayoi Yamamoto, Junko Oya, Tomoko Nakagami, Yasuko Uchigata","doi":"10.4137/JCM.S13564","DOIUrl":"https://doi.org/10.4137/JCM.S13564","url":null,"abstract":"Purpose: We examined the cross-sectional association between lung function and metabolic syndrome (MetS), independent of fasting immunoreactive insulin (F-IRI).Methods: A total of 3,072 middle-aged, apparently healthy subjects who participated in a general health check-up were included. Lung function, which was expressed as forced vital capacity (%FVC predicted) or forced expiratory volume in 1 second (FEV1% predicted) was examined. Multivariable logistic regression analysis was performed to assess the association between lung function and MetS.Results: Men with the lowest quartile of FVC% predicted, or those with the lowest quartile of FEV1% predicted, had a 3.5-fold or 2.6-fold increased risk of MetS, respectively, compared with those with the highest quartile of FVC% predicted or FEV1% predicted. F-IRI had a positive, significant, and independent association with MetS in both sexes.Conclusion: Impaired lung function increased the risk of MetS, independent of F-IRI and smoking in men, but not in women.","PeriodicalId":89792,"journal":{"name":"Japanese clinical medicine","volume":"5 ","pages":"1-8"},"PeriodicalIF":0.0,"publicationDate":"2014-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.4137/JCM.S13564","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"32327654","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 12

The Eradication of Helicobacter pylori does not Affect Glycemic Control in Japanese Subjects with Type 2 Diabetes. 根除幽门螺杆菌不会影响日本2型糖尿病患者的血糖控制。

Japanese clinical medicine Pub Date : 2013-05-15 eCollection Date: 2013-01-01 DOI: 10.4137/JCM.S10828

Yoshiharu Wada, Yoshiyuki Hamamoto, Yukiko Kawasaki, Sachiko Honjo, Kanta Fujimoto, Hisato Tatsuoka, Atsuko Matsuoka, Hiroki Ikeda, Jun Fujikawa, Hiroyuki Koshiyama

引用次数: 19

Presentation of a Patient who Underwent Fertility-Sparing Surgeries for Contralateral Recurrence of Ovarian Immature Teratoma with Gliomatosis Peritonei. 一例因对侧卵巢未成熟畸胎瘤伴腹膜胶质瘤病复发而行保留生育能力手术的患者报告。

Japanese clinical medicine Pub Date : 2013-05-06 eCollection Date: 2013-01-01 DOI: 10.4137/JCM.S11532

Saori Seo, Yoshinari Matsumoto, Miho Tsukioka, Toshiyuki Sumi, Kenichi Wakasa, Osamu Ishiko

{"title":"Presentation of a Patient who Underwent Fertility-Sparing Surgeries for Contralateral Recurrence of Ovarian Immature Teratoma with Gliomatosis Peritonei.","authors":"Saori Seo, Yoshinari Matsumoto, Miho Tsukioka, Toshiyuki Sumi, Kenichi Wakasa, Osamu Ishiko","doi":"10.4137/JCM.S11532","DOIUrl":"https://doi.org/10.4137/JCM.S11532","url":null,"abstract":"We report a patient who has maintained a regular menstrual cycle despite undergoing cystectomy and chemotherapy for contralateral recurrence of ovarian immature teratoma with gliomatosis peritonei. We initially performed a fertility-sparing right salpingo-oophorectomy, omentectomy and peritoneal biopsy for immature teratoma with gliomatosis peritonei, with adjuvant chemotherapy; we performed a left ovarian cystectomy and peritoneal biopsy for mature cystic teratoma with gliomatosis peritonei 16 months after the first surgery, a fertility-sparing left ovarian cystectomy and peritoneal biopsy for contralateral recurrence of ovarian immature teratoma with gliomatosis peritonei 60 months after the first surgery, and a left ovarian cystectomy and peritoneal and external iliac lymph node biopsy for endometrial cyst with gliomatosis peritonei 71 months after first surgery. The peritoneal gliomatosis lesions gradually decreased through the 4 surgeries over 8 years. The patient has maintained a regular menstrual cycle and currently shows no evidence of disease. ","PeriodicalId":89792,"journal":{"name":"Japanese clinical medicine","volume":"4 ","pages":"37-40"},"PeriodicalIF":0.0,"publicationDate":"2013-05-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.4137/JCM.S11532","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"31675315","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3

Hereditary Disorders with Defective Repair of UV-Induced DNA Damage. 紫外线诱导的DNA损伤修复缺陷的遗传性疾病。

Japanese clinical medicine Pub Date : 2013-04-16 eCollection Date: 2013-01-01 DOI: 10.4137/JCM.S10730

Shinichi Moriwaki

引用次数: 15

Pathological findings in a case of failed uterine artery embolization for placenta previa. 子宫动脉栓塞治疗前置胎盘失败1例病理分析。

Japanese clinical medicine Pub Date : 2013-04-14 eCollection Date: 2013-01-01 DOI: 10.4137/JCM.S11317

Natsuko Wada, Daisuke Tachibana, Kayoko Nakagawa, Hiroyuki Terada, Akemi Nakano, Toshiyuki Sumi, Masayasu Koyama, Osamu Ishiko, Norifumi Nishida

{"title":"Pathological findings in a case of failed uterine artery embolization for placenta previa.","authors":"Natsuko Wada, Daisuke Tachibana, Kayoko Nakagawa, Hiroyuki Terada, Akemi Nakano, Toshiyuki Sumi, Masayasu Koyama, Osamu Ishiko, Norifumi Nishida","doi":"10.4137/JCM.S11317","DOIUrl":"https://doi.org/10.4137/JCM.S11317","url":null,"abstract":"The reported success rate of uterine artery embolization (UAE) for obstetrical hemorrhage is more than 90%. We experienced a case of failed UAE for postpartum hemorrhage, although an embolic particle was found pathologically in the uterine vessels without coagulation. A 42-year-old woman (gravida 7, para 2) with placenta previa had genital bleeding at 35 weeks of gestation, and cesarean section was performed. We immediately added UAE aiming to reduce massive bleeding after the cesarean section, successful embolization of the bilateral uterine arteries and internal iliac arteries were confirmed by angiography regardless the vital sign was recovered with an appropriate amount of transfusion; the massive bleeding recurred after 1 hour of UAE. Hysterectomy was performed and pathological findings of the uterus showed that there was no coagulation in the vessels, which was supposed to be observed by the effect of gelatin sponge. In addition, despite the fact that no coagulation was found, only one gelatin sponge was found in 16 slices of the uterine wall specimens. We speculate that thrombotic materials were caught in vasoconstricted vessels triggered by hypovolemic shock due to acute blood loss, and then the gelatin sponge could be washed out after recovering to normalized circulation status leading to recurrent massive hemorrhage. ","PeriodicalId":89792,"journal":{"name":"Japanese clinical medicine","volume":"4 ","pages":"25-8"},"PeriodicalIF":0.0,"publicationDate":"2013-04-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.4137/JCM.S11317","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"31674898","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Pregnancy complicated by cervical varix and low-lying placenta: a case report. 妊娠合并宫颈静脉曲张及低位胎盘1例。

Japanese clinical medicine Pub Date : 2013-04-09 eCollection Date: 2013-01-01 DOI: 10.4137/JCM.S11276

Yasushi Kurihara, Daisuke Tachibana, Masatomo Teramae, Makiko Matsumoto, Hiroyuki Terada, Toshiyuki Sumi, Masayasu Koyama, Osamu Ishiko

引用次数: 11

Smoking counteracts the favorable effect of exercise training on endothelial function in patients with type 2 diabetes. 吸烟抵消了运动训练对2型糖尿病患者内皮功能的有利影响。

Japanese clinical medicine Pub Date : 2013-04-09 eCollection Date: 2013-01-01 DOI: 10.4137/JCM.S11152

Shinji Sato, Noriko Nakayama, Shingo Otsuki, Shiro Tanaka, Hajime Nakamura, Hiroyuki Koshiyama, Ryuji Nohara

{"title":"Smoking counteracts the favorable effect of exercise training on endothelial function in patients with type 2 diabetes.","authors":"Shinji Sato, Noriko Nakayama, Shingo Otsuki, Shiro Tanaka, Hajime Nakamura, Hiroyuki Koshiyama, Ryuji Nohara","doi":"10.4137/JCM.S11152","DOIUrl":"https://doi.org/10.4137/JCM.S11152","url":null,"abstract":"Background: Exercise training can improve endothelial function in patients with diabetes. We hypothesized that the favorable effect of exercise training on endothelial function in patients with diabetes is counteracted by cigarette smoking.Purpose: To assess whether there is a difference in the effect of exercise on endothelial function in smokers and non-smokers with type 2 diabetes.Methods: We performed a 3-month controlled trial in 27 never-smoking and 17 smoking individuals with type 2 diabetes who participated in a home-based walking program. The percentage decrease in post-exercise ankle-brachial pressure index (ABI), which is an index of endothelial function, was assessed at baseline and after 3 months.Results: Compared to the smoking group, the never-smoking group showed a more significant improvement in post exercise ABI during the 3 months of home-based training (interaction, P < 0.01).Conclusions: These results indicate that smoking may counteract the favorable effects of exercise training on endothelial function. Endothelial function plays an important role in the prevention of cardiovascular disease among patients with diabetes. Therefore, a Certified Diabetes Educator should strongly advise diabetic patients not to smoke.","PeriodicalId":89792,"journal":{"name":"Japanese clinical medicine","volume":"4 ","pages":"15-9"},"PeriodicalIF":0.0,"publicationDate":"2013-04-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.4137/JCM.S11152","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"31674896","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

A Case-Control Study of Esomeprazole Plus Rebamipide vs. Omeprazole Plus Rebamipide on Post-ESD Gastric Ulcers. 埃索美拉唑加雷巴米胺与奥美拉唑加雷巴米胺治疗esd后胃溃疡的病例对照研究

Japanese clinical medicine Pub Date : 2013-03-06 eCollection Date: 2013-01-01 DOI: 10.4137/JCM.S11320

Maki Bunno, Kyosuke Gouda, Kunihiro Yamahara, Masanori Kawaguchi

{"title":"A Case-Control Study of Esomeprazole Plus Rebamipide vs. Omeprazole Plus Rebamipide on Post-ESD Gastric Ulcers.","authors":"Maki Bunno, Kyosuke Gouda, Kunihiro Yamahara, Masanori Kawaguchi","doi":"10.4137/JCM.S11320","DOIUrl":"https://doi.org/10.4137/JCM.S11320","url":null,"abstract":"Objectives: Endoscopic submucosal dissection (ESD) is useful for treating gastric tumors. Several trials have shown the efficacy of 4 or 8 weeks of proton pump inhibitor (PPI) administration for post-ESD ulcers. However, if the size of the post-ESD ulcer is larger than predicted, PPI administration alone might not be sufficient for the ulcer to heal within 4 weeks. There is no report about the efficacy of post-ESD gastric ulcers by esomeprazole. We examined retrospectively the efficacy of a combination therapy of esomeprazole plus rebamipide, a mucosal-protective antiulcer drug, on the acceleration of post-ESD ulcer healing comparing with omeprazole plus rebamipide.Methods: We reviewed the medical records of patients who underwent ESD for gastric neoplasia. We conducted a case-control study to compare the healing rates within 4 weeks effected by esomeprazole plus rebamipide (group E) and omeprazole plus rebamipide (group O). The sizes of the artificial ulcers were divided into normal-sized or large-sized.Results: The baseline characteristics did not differ significantly between the two groups except age and sex. Stage S1 disease was observed in 27.6% and 38.7% of patients after 4 weeks of treatment in the group E and O, respectively. In large-sized artificial ulcers, the healing rate of stage S1 in group E is significantly higher than that in group O in 4 weeks.(25% VS 0%:P = 0.02).Conclusions: The safety and efficacy profiles of esomeprazole plus rebamipide and omeprazole and rebamipide are similar for the treatment of ESD-induced ulcers. In large-sized ulcers, esomeprazole plus rebamipide promotes ulcer healing.","PeriodicalId":89792,"journal":{"name":"Japanese clinical medicine","volume":"4 ","pages":"7-13"},"PeriodicalIF":0.0,"publicationDate":"2013-03-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.4137/JCM.S11320","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"31674895","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 11

Alkalizer administration improves renal function in hyperuricemia associated with obesity. 碱剂可改善与肥胖相关的高尿酸血症患者的肾功能。

Japanese clinical medicine Pub Date : 2013-02-03 eCollection Date: 2013-01-01 DOI: 10.4137/JCM.S10056

Jun Saito, Yoko Matsuzawa, Hiroko Ito, Masao Omura, Tomoshige Kino, Tetsuo Nishikawa

{"title":"Alkalizer administration improves renal function in hyperuricemia associated with obesity.","authors":"Jun Saito, Yoko Matsuzawa, Hiroko Ito, Masao Omura, Tomoshige Kino, Tetsuo Nishikawa","doi":"10.4137/JCM.S10056","DOIUrl":"https://doi.org/10.4137/JCM.S10056","url":null,"abstract":"We evaluated the combination effect of the alkalizer citrate with the xanthine oxidase inhibitor allopurinol on renal function and uric acid in patients with hyperuricemia associated with obesity and/or metabolic syndrome (MetS), who were extracted from among the subjects enrolled in a prospective randomized controlled study aimed at assessing the efficacy of such a combination for improving renal function. We also conducted a post hoc analysis to examine influences on lipid profiles. Patients who consented to participate in the study were randomly allocated to receive either allopurinol alone (monotherapy) or in combination with a citrate preparation (combination therapy). The analysis population consisted of 31 obese patients with a body mass index greater than 25 kg/m(2) (monotherapy, 15 patients; combination therapy, 16 patients). The creatinine clearance rate (Ccr), serum uric acid levels, and lipid profiles were measured before and at 12 weeks after the start of treatment. In the combination therapy group, Ccr increased significantly and serum uric acid levels decreased significantly in obese patients, while Ccr tended to increase and serum uric acid levels decreased, though not significantly, in patients with MetS-related clinical parameters. Overall, blood triglyceride levels tended to improve in the combination therapy group as compared with the monotherapy group. ","PeriodicalId":89792,"journal":{"name":"Japanese clinical medicine","volume":"4 ","pages":"1-6"},"PeriodicalIF":0.0,"publicationDate":"2013-02-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.4137/JCM.S10056","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"31674894","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 4