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Biophotonics Congress: Optics in the Life Sciences Congress 2019 (BODA,BRAIN,NTM,OMA,OMP)最新文献

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Multiplexed Intensity Diffraction Tomography (mIDT) for Dynamic, Label-Free Volumetric Biological Imaging 用于动态、无标记体积生物成像的多路强度衍射层析成像(mIDT)
Biophotonics Congress: Optics in the Life Sciences Congress 2019 (BODA,BRAIN,NTM,OMA,OMP) Pub Date : 2019-04-14 DOI: 10.1364/BODA.2019.JW4C.2
Alex Matlock, Ji Yi, L. Tian
{"title":"Multiplexed Intensity Diffraction Tomography (mIDT) for Dynamic, Label-Free Volumetric Biological Imaging","authors":"Alex Matlock, Ji Yi, L. Tian","doi":"10.1364/BODA.2019.JW4C.2","DOIUrl":"https://doi.org/10.1364/BODA.2019.JW4C.2","url":null,"abstract":"We present multiplexed Intensity Diffraction Tomography (mIDT) for live biological sample imaging. We achieve 100X imaging speed improvements using model-based multiplexed LED illuminations that maintain high-quality 3D object reconstructions.","PeriodicalId":8973,"journal":{"name":"Biophotonics Congress: Optics in the Life Sciences Congress 2019 (BODA,BRAIN,NTM,OMA,OMP)","volume":"83 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-04-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79335458","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Toward Single-Lens Epi-Fluorescent Light Sheet Microscopy with Single-Pixel Detection 具有单像素检测的单透镜外延荧光片显微镜
Biophotonics Congress: Optics in the Life Sciences Congress 2019 (BODA,BRAIN,NTM,OMA,OMP) Pub Date : 2019-04-14 DOI: 10.1364/NTM.2019.NW5C.3
J. Field, R. Bartels
{"title":"Toward Single-Lens Epi-Fluorescent Light Sheet Microscopy with Single-Pixel Detection","authors":"J. Field, R. Bartels","doi":"10.1364/NTM.2019.NW5C.3","DOIUrl":"https://doi.org/10.1364/NTM.2019.NW5C.3","url":null,"abstract":"We report a method for epi-fluorescent light-sheet microscopy with a single-element detector. This method is based on spatial frequency projection imaging and utilizes PSF engineering to enhance the depth of field.","PeriodicalId":8973,"journal":{"name":"Biophotonics Congress: Optics in the Life Sciences Congress 2019 (BODA,BRAIN,NTM,OMA,OMP)","volume":"91 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-04-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76726276","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
High-speed Multicolor Coherent Raman Imaging Enabled by a Novel Fiber Optical Parametric Oscillator 一种新型光纤参量振荡器实现高速多色相干拉曼成像
Biophotonics Congress: Optics in the Life Sciences Congress 2019 (BODA,BRAIN,NTM,OMA,OMP) Pub Date : 2019-04-14 DOI: 10.1364/NTM.2019.NT1C.2
T. Hellwig, M. Brinkmann, Alexander Fast, C. Evans, C. Fallnich
{"title":"High-speed Multicolor Coherent Raman Imaging Enabled by a Novel Fiber Optical Parametric Oscillator","authors":"T. Hellwig, M. Brinkmann, Alexander Fast, C. Evans, C. Fallnich","doi":"10.1364/NTM.2019.NT1C.2","DOIUrl":"https://doi.org/10.1364/NTM.2019.NT1C.2","url":null,"abstract":"We present high-speed multicolor coherent Raman imaging enabled by a robust fiber optical parametric oscillator tunable in 5 ms per arbitrary wavelength step without the need for a mechanical delay.","PeriodicalId":8973,"journal":{"name":"Biophotonics Congress: Optics in the Life Sciences Congress 2019 (BODA,BRAIN,NTM,OMA,OMP)","volume":"26 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-04-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78512353","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Development of a GPU-accelerated constrained reconstruction algorithm for compressed fluorescence lifetime imaging microscopy 一种gpu加速的压缩荧光寿命成像显微镜约束重建算法的开发
Biophotonics Congress: Optics in the Life Sciences Congress 2019 (BODA,BRAIN,NTM,OMA,OMP) Pub Date : 2019-04-14 DOI: 10.1364/boda.2019.jw4c.5
Yayao Ma, Riwei Jin, Liang Gao
{"title":"Development of a GPU-accelerated constrained reconstruction algorithm for compressed fluorescence lifetime imaging microscopy","authors":"Yayao Ma, Riwei Jin, Liang Gao","doi":"10.1364/boda.2019.jw4c.5","DOIUrl":"https://doi.org/10.1364/boda.2019.jw4c.5","url":null,"abstract":"We present a GPU-accelerated constrained reconstruction algorithm which improves image quality and reconstruction speed for compressed fluorescence lifetime microscopy.","PeriodicalId":8973,"journal":{"name":"Biophotonics Congress: Optics in the Life Sciences Congress 2019 (BODA,BRAIN,NTM,OMA,OMP)","volume":"29 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-04-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80440962","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Deep-imaging with time-of-flight diffusive optical tomography 飞行时间漫射光学层析成像
Biophotonics Congress: Optics in the Life Sciences Congress 2019 (BODA,BRAIN,NTM,OMA,OMP) Pub Date : 2019-04-14 DOI: 10.1364/BODA.2019.JW3B.3
D. Faccio, A. Lyons, F. Tonolini, R. Murray-Smith
{"title":"Deep-imaging with time-of-flight diffusive optical tomography","authors":"D. Faccio, A. Lyons, F. Tonolini, R. Murray-Smith","doi":"10.1364/BODA.2019.JW3B.3","DOIUrl":"https://doi.org/10.1364/BODA.2019.JW3B.3","url":null,"abstract":"Recent progress in computational techniques and quantum detection technologies allow to reconstruct images of objects with mm-resolution hidden inside deep (5 cm), strongly diffusive, opaque materials with applications in deep body imaging.","PeriodicalId":8973,"journal":{"name":"Biophotonics Congress: Optics in the Life Sciences Congress 2019 (BODA,BRAIN,NTM,OMA,OMP)","volume":"39 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-04-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86197581","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Arthroscopic Near-Infrared Spectroscopic Prediction of Human Meniscus Properties 人体半月板特性的关节镜近红外光谱预测
Biophotonics Congress: Optics in the Life Sciences Congress 2019 (BODA,BRAIN,NTM,OMA,OMP) Pub Date : 2019-04-14 DOI: 10.1364/BODA.2019.JT4A.35
Juho Ala-Myllymäki, T. Paakkonen, J. Töyräs, I. Afara
{"title":"Arthroscopic Near-Infrared Spectroscopic Prediction of Human Meniscus Properties","authors":"Juho Ala-Myllymäki, T. Paakkonen, J. Töyräs, I. Afara","doi":"10.1364/BODA.2019.JT4A.35","DOIUrl":"https://doi.org/10.1364/BODA.2019.JT4A.35","url":null,"abstract":"We investigate the potential of near-infrared spectroscopy for estimating the properties of human meniscus during arthroscopy. In vitro predictive models were developed and tested on ex vivo arthroscopic near-infrared spectroscopy measurements.","PeriodicalId":8973,"journal":{"name":"Biophotonics Congress: Optics in the Life Sciences Congress 2019 (BODA,BRAIN,NTM,OMA,OMP)","volume":"15 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-04-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78572246","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Chemical imaging for Biomedicine 生物医学化学成像
Biophotonics Congress: Optics in the Life Sciences Congress 2019 (BODA,BRAIN,NTM,OMA,OMP) Pub Date : 2019-04-14 DOI: 10.1364/OMP.2019.OT3D.3
Lu Wei
{"title":"Chemical imaging for Biomedicine","authors":"Lu Wei","doi":"10.1364/OMP.2019.OT3D.3","DOIUrl":"https://doi.org/10.1364/OMP.2019.OT3D.3","url":null,"abstract":"I will present two chemical imaging strategies to address two existing fundamental challenges in optical bio-imaging. First, we devised a Bioorthogonal Chemical Imaging platform suited for probing the dynamics of small bio-molecules. Second, we developed a super-multiplex vibrational imaging method, coupling the narrow Raman linewidth with sensitivity boost from resonance enhancement. It is capable of resolving up to 24 colors simultaneously.","PeriodicalId":8973,"journal":{"name":"Biophotonics Congress: Optics in the Life Sciences Congress 2019 (BODA,BRAIN,NTM,OMA,OMP)","volume":"42 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-04-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73844180","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Lifting Wavelet and KL Transform(LWKL) Based CT and MRI Image Fusion Scheme 基于提升小波和KL变换(LWKL)的CT与MRI图像融合方案
Biophotonics Congress: Optics in the Life Sciences Congress 2019 (BODA,BRAIN,NTM,OMA,OMP) Pub Date : 2019-04-14 DOI: 10.1364/BODA.2019.JT4A.5
J. Bhardwaj, A. Nayak
{"title":"Lifting Wavelet and KL Transform(LWKL) Based CT and MRI Image Fusion Scheme","authors":"J. Bhardwaj, A. Nayak","doi":"10.1364/BODA.2019.JT4A.5","DOIUrl":"https://doi.org/10.1364/BODA.2019.JT4A.5","url":null,"abstract":"The proposed method has proved an efficient methodology in the transform based image fusion schemes .The attractable properties of both Lifting wavelet and KL Transform (LWKL method) are employed.","PeriodicalId":8973,"journal":{"name":"Biophotonics Congress: Optics in the Life Sciences Congress 2019 (BODA,BRAIN,NTM,OMA,OMP)","volume":"9 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-04-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80639139","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 4
Human anti-NR1 autoantibodies induce synaptic pathology with functional relevant loss of postsynaptic NMDA receptors 人抗nr1自身抗体诱导突触病理与突触后NMDA受体的功能相关丧失
Biophotonics Congress: Optics in the Life Sciences Congress 2019 (BODA,BRAIN,NTM,OMA,OMP) Pub Date : 2019-04-14 DOI: 10.1364/boda.2019.jt4a.12
L. Schmidl, Luise Röpke, M. Ceanga, J. Kreye, N. K. Wenke, H. Haselmann, H. Prüss, C. Geis
{"title":"Human anti-NR1 autoantibodies induce synaptic pathology with functional relevant loss of postsynaptic NMDA receptors","authors":"L. Schmidl, Luise Röpke, M. Ceanga, J. Kreye, N. K. Wenke, H. Haselmann, H. Prüss, C. Geis","doi":"10.1364/boda.2019.jt4a.12","DOIUrl":"https://doi.org/10.1364/boda.2019.jt4a.12","url":null,"abstract":"We investigated the pathogenic role of anti-N-Methyl-D-aspartate receptor (NMDAR) antibodies in neurons and in a mouse model of autoimmune encephalitis using LSM and super-resolution microscopy. We found a functional reduction of synaptic NMDARs.","PeriodicalId":8973,"journal":{"name":"Biophotonics Congress: Optics in the Life Sciences Congress 2019 (BODA,BRAIN,NTM,OMA,OMP)","volume":"2 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-04-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82623527","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Femto-Seq: A New Nonlinear Microcopy Approach for Elucidating Chromatin Structure at the Single Gene Level Femto-Seq:在单基因水平上阐明染色质结构的一种新的非线性显微复制方法
Biophotonics Congress: Optics in the Life Sciences Congress 2019 (BODA,BRAIN,NTM,OMA,OMP) Pub Date : 2019-04-14 DOI: 10.1364/ntm.2019.ns2b.5
Max H Kushner, Juan Wang, A. Ozer, J. Ray, Hening Lin, J. Lis, W. Zipfel
{"title":"Femto-Seq: A New Nonlinear Microcopy Approach for Elucidating Chromatin Structure at the Single Gene Level","authors":"Max H Kushner, Juan Wang, A. Ozer, J. Ray, Hening Lin, J. Lis, W. Zipfel","doi":"10.1364/ntm.2019.ns2b.5","DOIUrl":"https://doi.org/10.1364/ntm.2019.ns2b.5","url":null,"abstract":"Femto-Seq is a new nonlinear optical methodology that provides a means to determine the chromatin environment at the base-pair level at and around any site in the nucleus that can be identified by imaging.","PeriodicalId":8973,"journal":{"name":"Biophotonics Congress: Optics in the Life Sciences Congress 2019 (BODA,BRAIN,NTM,OMA,OMP)","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-04-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83210027","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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