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Biophotonics Congress: Optics in the Life Sciences Congress 2019 (BODA,BRAIN,NTM,OMA,OMP)最新文献

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Laser refrigeration of ytterbium-doped alkali-yttrium-fluoride nanostructures (Yb:MYF, M = K, Na, Li) 掺镱碱氟化钇纳米结构(Yb:MYF, M = K, Na, Li)的激光制冷
Biophotonics Congress: Optics in the Life Sciences Congress 2019 (BODA,BRAIN,NTM,OMA,OMP) Pub Date : 2019-04-15 DOI: 10.1364/oma.2019.aw4e.2
Xiaojing Xia, Greg Felsted, Anupum Pant, E. Dobretsova, P. Pauzauskie
{"title":"Laser refrigeration of ytterbium-doped alkali-yttrium-fluoride nanostructures (Yb:MYF, M = K, Na, Li)","authors":"Xiaojing Xia, Greg Felsted, Anupum Pant, E. Dobretsova, P. Pauzauskie","doi":"10.1364/oma.2019.aw4e.2","DOIUrl":"https://doi.org/10.1364/oma.2019.aw4e.2","url":null,"abstract":"Single-beam laser tweezers with a tunable NIR trapping wavelength are used to analyze cold Brownian motion (CBM) dynamics of ytterbium-doped alkali yttrium fluoride (Yb:MYF, M=Li, Na, K) nanostructures.","PeriodicalId":8973,"journal":{"name":"Biophotonics Congress: Optics in the Life Sciences Congress 2019 (BODA,BRAIN,NTM,OMA,OMP)","volume":"40 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88439948","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Determination of twisting of kinesin molecules during stepping 步进过程中驱动蛋白分子扭曲的测定
Biophotonics Congress: Optics in the Life Sciences Congress 2019 (BODA,BRAIN,NTM,OMA,OMP) Pub Date : 2019-04-15 DOI: 10.1364/OMA.2019.AM2E.1
Basudev Roy, Avin Ramaiya, E. Schäffer
{"title":"Determination of twisting of kinesin molecules during stepping","authors":"Basudev Roy, Avin Ramaiya, E. Schäffer","doi":"10.1364/OMA.2019.AM2E.1","DOIUrl":"https://doi.org/10.1364/OMA.2019.AM2E.1","url":null,"abstract":"Kinesin molecules “walk” on microtubules with 8 nm steps. Typically, it is believed to not twist during the motilty. It is this very aspect that we probe using birefringent microspheres of liquid crystalline material RM257 (Merck) upon placing them under crossed polarizers during motility and also using the Optical Micro-Protractor that uses the optical tweezers and detect the twist and the torque generated by the kinesin molecules during stepping.","PeriodicalId":8973,"journal":{"name":"Biophotonics Congress: Optics in the Life Sciences Congress 2019 (BODA,BRAIN,NTM,OMA,OMP)","volume":"8 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84102084","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Imaging the behavior and neural activity of freely moving organisms with a gigapixel microscope 用十亿像素的显微镜对自由移动的生物体的行为和神经活动进行成像
Biophotonics Congress: Optics in the Life Sciences Congress 2019 (BODA,BRAIN,NTM,OMA,OMP) Pub Date : 2019-04-14 DOI: 10.1364/brain.2019.bt3a.3
M. Harfouche, Timothy W. Dunn, Eva A Naumann, R. Horstmeyer
{"title":"Imaging the behavior and neural activity of freely moving organisms with a gigapixel microscope","authors":"M. Harfouche, Timothy W. Dunn, Eva A Naumann, R. Horstmeyer","doi":"10.1364/brain.2019.bt3a.3","DOIUrl":"https://doi.org/10.1364/brain.2019.bt3a.3","url":null,"abstract":"We present a micro-camera array microscope that images at cellular-level detail across hundreds of square centimeters. We demonstrate how this microscope can image the behavior and fluorescent neural activity of freely swimming zebrafish","PeriodicalId":8973,"journal":{"name":"Biophotonics Congress: Optics in the Life Sciences Congress 2019 (BODA,BRAIN,NTM,OMA,OMP)","volume":"25 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-04-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74014259","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Visible-light optical coherence tomography investigation into vasculature changes following microprism implantation 微棱镜植入后血管变化的可见光光学相干断层扫描研究
Biophotonics Congress: Optics in the Life Sciences Congress 2019 (BODA,BRAIN,NTM,OMA,OMP) Pub Date : 2019-04-14 DOI: 10.1364/brain.2019.bt2a.2
Lisa Beckmann, Xian Zhang, Hao F. Zhang
{"title":"Visible-light optical coherence tomography investigation into vasculature changes following microprism implantation","authors":"Lisa Beckmann, Xian Zhang, Hao F. Zhang","doi":"10.1364/brain.2019.bt2a.2","DOIUrl":"https://doi.org/10.1364/brain.2019.bt2a.2","url":null,"abstract":"A chronically implanted microprism in the rodent cortex enables cross-sectional imaging of all the key cortical layers. We determined the time course of recovery from this surgical implantation using visible-light optical coherence tomography angiography.","PeriodicalId":8973,"journal":{"name":"Biophotonics Congress: Optics in the Life Sciences Congress 2019 (BODA,BRAIN,NTM,OMA,OMP)","volume":"29 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-04-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74889090","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Fabrication of Multi-Layered Bone Scaffolds using Femtosecond Pulsed Lasers 飞秒脉冲激光制备多层骨支架
Biophotonics Congress: Optics in the Life Sciences Congress 2019 (BODA,BRAIN,NTM,OMA,OMP) Pub Date : 2019-04-14 DOI: 10.1364/boda.2019.jt4a.45
N. Iqbal, A. Anastasiou, C. Maddi, Mostafa El-Raif, P. Giannoudis, A. Jha
{"title":"Fabrication of Multi-Layered Bone Scaffolds using Femtosecond Pulsed Lasers","authors":"N. Iqbal, A. Anastasiou, C. Maddi, Mostafa El-Raif, P. Giannoudis, A. Jha","doi":"10.1364/boda.2019.jt4a.45","DOIUrl":"https://doi.org/10.1364/boda.2019.jt4a.45","url":null,"abstract":"An IR femtosecond pulsed laser was used for micropatterning of biomineral containing chitosan membranes, aiming to enhance bone mineralization and angiogenesis. Pre and post irradiation materials have been characterized with XRD, SEM and spectroscopic techniques.","PeriodicalId":8973,"journal":{"name":"Biophotonics Congress: Optics in the Life Sciences Congress 2019 (BODA,BRAIN,NTM,OMA,OMP)","volume":"17 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-04-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73958536","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A multimodal light-sheet microscope that is compatible with all clearing techniques 一种与所有清除技术兼容的多模态光片显微镜
Biophotonics Congress: Optics in the Life Sciences Congress 2019 (BODA,BRAIN,NTM,OMA,OMP) Pub Date : 2019-04-14 DOI: 10.1364/NTM.2019.NW5C.6
Tonmoy Chakraborty, K. Dean, Hu Zhao, R. Fiolka
{"title":"A multimodal light-sheet microscope that is compatible with all clearing techniques","authors":"Tonmoy Chakraborty, K. Dean, Hu Zhao, R. Fiolka","doi":"10.1364/NTM.2019.NW5C.6","DOIUrl":"https://doi.org/10.1364/NTM.2019.NW5C.6","url":null,"abstract":"Combined with optical clearing protocols, light-sheet microscopy offers rapid and sensitive imaging of whole organs. We report a light sheet microscope with isotropic, submicron resolution that is compatible a refractive index range of 1.33-1.56.","PeriodicalId":8973,"journal":{"name":"Biophotonics Congress: Optics in the Life Sciences Congress 2019 (BODA,BRAIN,NTM,OMA,OMP)","volume":"133 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-04-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74212913","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Labeling Circulating Tumor Cells with a Folate Receptor Targeted Probe for Diffuse in-vivo Flow Cytometry 用叶酸受体靶向探针在弥漫性体内流式细胞术中标记循环肿瘤细胞
Biophotonics Congress: Optics in the Life Sciences Congress 2019 (BODA,BRAIN,NTM,OMA,OMP) Pub Date : 2019-04-14 DOI: 10.1364/omp.2019.om3d.4
Roshani A. Patil, S. Madduri, P. Low, M. Niedre
{"title":"Labeling Circulating Tumor Cells with a Folate Receptor Targeted Probe for Diffuse in-vivo Flow Cytometry","authors":"Roshani A. Patil, S. Madduri, P. Low, M. Niedre","doi":"10.1364/omp.2019.om3d.4","DOIUrl":"https://doi.org/10.1364/omp.2019.om3d.4","url":null,"abstract":"Diffuse in-vivo Flow Cytometry is a new method to enumerate fluorescently-labeled circulating tumor cells in-vivo. Herein, we investigated the use of a folate receptor-targeted fluorescence probe EC17 for labeling of target cells in the bloodstream.","PeriodicalId":8973,"journal":{"name":"Biophotonics Congress: Optics in the Life Sciences Congress 2019 (BODA,BRAIN,NTM,OMA,OMP)","volume":"61 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-04-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74229308","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Fluorescent Lifetime Imaging improved via Deep Learning 通过深度学习改进荧光寿命成像
Biophotonics Congress: Optics in the Life Sciences Congress 2019 (BODA,BRAIN,NTM,OMA,OMP) Pub Date : 2019-04-14 DOI: 10.1364/ntm.2019.nm3c.4
Jason T. Smith, Nathan Un, Ruoyang Yao, Nattawut Sinsuebphon, Alena Rudkouskaya, J. Mazurkiewicz, Margarida M Barroso, Pingkun Yan, X. Intes
{"title":"Fluorescent Lifetime Imaging improved via Deep Learning","authors":"Jason T. Smith, Nathan Un, Ruoyang Yao, Nattawut Sinsuebphon, Alena Rudkouskaya, J. Mazurkiewicz, Margarida M Barroso, Pingkun Yan, X. Intes","doi":"10.1364/ntm.2019.nm3c.4","DOIUrl":"https://doi.org/10.1364/ntm.2019.nm3c.4","url":null,"abstract":"Herein, we present a novel workflow based on Deep Learning (DL) trained on synthetic data to quantify fluorescence lifetime imaging of experimental data across multiple microscopic and macroscopic applications with unprecedented accuracy and computational speed.","PeriodicalId":8973,"journal":{"name":"Biophotonics Congress: Optics in the Life Sciences Congress 2019 (BODA,BRAIN,NTM,OMA,OMP)","volume":"7 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-04-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78435453","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Dual-view Inverted Selective Plane Illumination Microscopy for Accurate 3D Digital Pathology on Large Specimens 双视图倒置选择平面照明显微镜准确的3D数字病理大标本
Biophotonics Congress: Optics in the Life Sciences Congress 2019 (BODA,BRAIN,NTM,OMA,OMP) Pub Date : 2019-04-14 DOI: 10.1364/NTM.2019.NT3C.3
Bihe Hu, Guang Li, Andrew B. Sholl, J. Q. Brown
{"title":"Dual-view Inverted Selective Plane Illumination Microscopy for Accurate 3D Digital Pathology on Large Specimens","authors":"Bihe Hu, Guang Li, Andrew B. Sholl, J. Q. Brown","doi":"10.1364/NTM.2019.NT3C.3","DOIUrl":"https://doi.org/10.1364/NTM.2019.NT3C.3","url":null,"abstract":"diSPIM is used to render 3D digital histological images on large specimens. By comparing dual-view deconvolved results with the corresponding single-view images, we demonstrate that dual-view imaging can provide higher image accuracy.","PeriodicalId":8973,"journal":{"name":"Biophotonics Congress: Optics in the Life Sciences Congress 2019 (BODA,BRAIN,NTM,OMA,OMP)","volume":"5 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-04-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74941664","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Molecular Chemical Imaging of Critical Anatomical Structures in vivo 体内关键解剖结构的分子化学成像
Biophotonics Congress: Optics in the Life Sciences Congress 2019 (BODA,BRAIN,NTM,OMA,OMP) Pub Date : 2019-04-14 DOI: 10.1364/omp.2019.om4d.3
Aaron Smith, A. Samiei, J. Lyne, C. Post, Shona Stewart, Heather Gomer, Jihang Wang, Jeffrey A. Cohen, P. Treado
{"title":"Molecular Chemical Imaging of Critical Anatomical Structures in vivo","authors":"Aaron Smith, A. Samiei, J. Lyne, C. Post, Shona Stewart, Heather Gomer, Jihang Wang, Jeffrey A. Cohen, P. Treado","doi":"10.1364/omp.2019.om4d.3","DOIUrl":"https://doi.org/10.1364/omp.2019.om4d.3","url":null,"abstract":"Improved patient outcomes highlight the need to avoid errors in surgery. Molecular Chemical Imaging (MCI) aids in identifying critical structures without reagents and in vivo results are presented for a range of surgical applications.","PeriodicalId":8973,"journal":{"name":"Biophotonics Congress: Optics in the Life Sciences Congress 2019 (BODA,BRAIN,NTM,OMA,OMP)","volume":"23 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-04-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78166451","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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