{"title":"Chemical imaging for Biomedicine","authors":"Lu Wei","doi":"10.1364/OMP.2019.OT3D.3","DOIUrl":null,"url":null,"abstract":"I will present two chemical imaging strategies to address two existing fundamental challenges in optical bio-imaging. First, we devised a Bioorthogonal Chemical Imaging platform suited for probing the dynamics of small bio-molecules. Second, we developed a super-multiplex vibrational imaging method, coupling the narrow Raman linewidth with sensitivity boost from resonance enhancement. It is capable of resolving up to 24 colors simultaneously.","PeriodicalId":8973,"journal":{"name":"Biophotonics Congress: Optics in the Life Sciences Congress 2019 (BODA,BRAIN,NTM,OMA,OMP)","volume":"42 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2019-04-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Biophotonics Congress: Optics in the Life Sciences Congress 2019 (BODA,BRAIN,NTM,OMA,OMP)","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1364/OMP.2019.OT3D.3","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
I will present two chemical imaging strategies to address two existing fundamental challenges in optical bio-imaging. First, we devised a Bioorthogonal Chemical Imaging platform suited for probing the dynamics of small bio-molecules. Second, we developed a super-multiplex vibrational imaging method, coupling the narrow Raman linewidth with sensitivity boost from resonance enhancement. It is capable of resolving up to 24 colors simultaneously.