Open surgical oncology journal (Online)最新文献_第3页

Implementation and Early Results of Extended Lymph Node Dissection for Gastric Cancer in a Non-Specialized Western Center§~!2010-02-19~!2010-03-03~!2010-04-21~! 胃癌扩大淋巴结清扫术在西部非专科中心的实施及早期效果2010-02-19 2010-03-03 2010-04-21

Open surgical oncology journal (Online) Pub Date : 2010-05-04 DOI: 10.2174/1876504101002010004

M. Catarci, S. Ghinassi, A. Cintio, L. Montemurro, L. Pinnarelli, L. Leone, G. Longo, G. Grassi

{"title":"Implementation and Early Results of Extended Lymph Node Dissection for Gastric Cancer in a Non-Specialized Western Center§~!2010-02-19~!2010-03-03~!2010-04-21~!","authors":"M. Catarci, S. Ghinassi, A. Cintio, L. Montemurro, L. Pinnarelli, L. Leone, G. Longo, G. Grassi","doi":"10.2174/1876504101002010004","DOIUrl":"https://doi.org/10.2174/1876504101002010004","url":null,"abstract":"Background: The optimal degree of lymph node dissection for gastric cancer is still matter of debate. Particularly, there are serious doubts about the reproducibility of extended lymph node dissection in western surgical units, and no studies to date have investigated factors influencing early results (mortality, major morbidity and reoperation rates) during the learning curve. Methods: Univariate and multivariate analysis of 19 variables on a prospective series of 313 consecutive resections for gastric cancer performed by ten different surgeons. Endpoints were mortality, major morbidity and reoperation rates, calculated within 60 days form the operation. Results: Early results were all independently influenced by the presence of comorbidities alone. ASA status III-IV vs I-II determined a higher operative mortality rate (11.9% vs 0.5%; Odds Ratio 12.3; 95% c.i. 1.53 to 98.1; p .018), a higher major morbidity rate (39.7% vs 16.6%; Odds Ratio 2.71; 95% c.i. 1.51 to 4.88; p .0008) and a higher reoperation rate (9.5% vs 2.1%; Odds Ratio 4.81; 95% c.i. 1.51 to 15.3; p .008). Conclusions: Extended lymph node dissection can be safely implemented into the clinical practice of a non-dedicated western institution by providing adequate coaching from more expert surgeons. This implementation protocol led to acceptable rates of operative morbi-mortality, independently influenced only by the comorbidity status.","PeriodicalId":89705,"journal":{"name":"Open surgical oncology journal (Online)","volume":"116 1","pages":"4-10"},"PeriodicalIF":0.0,"publicationDate":"2010-05-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68143178","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Near-Infrared Fluorescence Imaging in Humans with Indocyanine Green: A Review and Update. 吲哚菁绿对人体近红外荧光成像的研究进展。

Open surgical oncology journal (Online) Pub Date : 2010-01-01 DOI: 10.2174/1876504101002010012

Milton V Marshall, John C Rasmussen, I-Chih Tan, Melissa B Aldrich, Kristen E Adams, Xuejuan Wang, Caroline E Fife, Erik A Maus, Latisha A Smith, Eva M Sevick-Muraca

{"title":"Near-Infrared Fluorescence Imaging in Humans with Indocyanine Green: A Review and Update.","authors":"Milton V Marshall, John C Rasmussen, I-Chih Tan, Melissa B Aldrich, Kristen E Adams, Xuejuan Wang, Caroline E Fife, Erik A Maus, Latisha A Smith, Eva M Sevick-Muraca","doi":"10.2174/1876504101002010012","DOIUrl":"10.2174/1876504101002010012","url":null,"abstract":"<p><p>Near-infrared (NIR) fluorescence imaging clinical studies have been reported in the literature with six different devices that employ various doses of indocyanine green (ICG) as a non-specific contrast agent. To date, clinical applications range from (i) angiography, intraoperative assessment of vessel patency, and tumor/metastasis delineation following intravenous administration of ICG, and (ii) imaging lymphatic architecture and function following subcutaneous and intradermal ICG administration. In the latter case, NIR fluorescence imaging may enable new discoveries associated with lymphatic function due to (i) a unique niche that is not met by any other conventional imaging technology and (ii) its exquisite sensitivity enabling high spatial and temporal resolution. Herein, we (i) review the basics of clinical NIR fluorescence imaging, (ii) survey the literature on clinical application of investigational devices using ICG fluorescent contrast, (iii) provide an update of non-invasive dynamic lymphatic imaging conducted with our FDPM device, and finally, (iv) comment on the future NIR fluorescence imaging for non-invasive and intraoperative use given recent demonstrations showing capabilities for imaging following microdose administration of contrast agent.</p>","PeriodicalId":89705,"journal":{"name":"Open surgical oncology journal (Online)","volume":"2 2","pages":"12-25"},"PeriodicalIF":0.0,"publicationDate":"2010-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3424734/pdf/nihms219991.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"30858985","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Low-Grade Extranodal Marginal Zone B Cell Lymphoma of Malt in the Kidney 肾低级别结外边缘区B细胞淋巴瘤

Open surgical oncology journal (Online) Pub Date : 2009-10-29 DOI: 10.2174/1876504100901010012

Y. Jeon, J. Ku

引用次数: 1

Novel Case of Metastatic Testicular Immature Teratoma Invading the Duodenum 转移性睾丸未成熟畸胎瘤侵犯十二指肠新病例

Open surgical oncology journal (Online) Pub Date : 2009-10-23 DOI: 10.2174/1876504100901010016

T. V. Johnson, A. Osunkoya, K. Delman, D. Baumgarten, V. Master

引用次数: 3

Isolated Scapular Metastasis in a Patient with Gallbladder Carcinoma: Case Report 胆囊癌患者分离性肩胛骨转移1例

Open surgical oncology journal (Online) Pub Date : 2009-09-08 DOI: 10.2174/1876504100901010010

M. Kulkarni, Vijay Ramachandran, N. Dash, S. Pal, P. Sahni, T. Chattopadhyay

引用次数: 1

Retroperitoneal Tumour Masquerading as Mesenchymal Neoplasm of the Liver 腹膜后肿瘤伪装成肝脏间质肿瘤

Open surgical oncology journal (Online) Pub Date : 2009-06-18 DOI: 10.2174/1876504100901010008

Vijay Ramachandran, G. Ramesh, B. Vydehi

引用次数: 0

CD44 and CD133 Expressions in Primary Tumor Cells Correlate to Survival of Pancreatic Cancer Patients 原发性肿瘤细胞中CD44和CD133的表达与胰腺癌患者的生存相关

Open surgical oncology journal (Online) Pub Date : 2009-04-28 DOI: 10.2174/1876504100901010001

S. Qiang, H. Shinchi, H. Kurahara, Yuko Mataki, K. Maemura, S. Natsugoe, S. Takao

{"title":"CD44 and CD133 Expressions in Primary Tumor Cells Correlate to Survival of Pancreatic Cancer Patients","authors":"S. Qiang, H. Shinchi, H. Kurahara, Yuko Mataki, K. Maemura, S. Natsugoe, S. Takao","doi":"10.2174/1876504100901010001","DOIUrl":"https://doi.org/10.2174/1876504100901010001","url":null,"abstract":"Background: Recent studies have suggested that CD44 and/or CD133 expressing pancreatic cancer cells have potential abilities of self-renewal, tumorigenesis and tumor metastasis. The aim of this study was to investigate whether CD44 and CD133 expressions in primary tumor cells correlate to the survival and clinicopathological findings of pancre- atic cancer patients. Methods: Pancreatic head carcinoma specimens from 80 patients who underwent surgical resection were immunohisto- chemically assessed for CD44 and CD133 expressions. Results: Of the 80 specimens, 34 (42.5 %) and 48 (60%) specimens were immunohistochemically positive for CD44 and CD133 expression, respectively. CD44 was expressed on the cell surface and CD133 expression was observed in the cy- toplasm of the positive cells, which were located at the peripheral adenocarcinoma glandular structures. There was no sig- nificant difference in the 5-year survival rate of patients based on CD44 expression, but the 5-year survival rate of CD133-positive patients was significantly lower than that of CD133-negative patients (P = 0.0002). Multivariate analysis revealed that CD44-positive and CD133-negative expression was a favorable prognostic indicator (P = 0.0424). Conclusions: CD44 and CD133 expressions are association with survival and malignant behavior in pancreatic cancer pa- tients.","PeriodicalId":89705,"journal":{"name":"Open surgical oncology journal (Online)","volume":"1 1","pages":"1-7"},"PeriodicalIF":0.0,"publicationDate":"2009-04-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68143225","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 7