Biomedicine & Pharmacotherapy最新文献

{"title":"Corrigendum to \"VP3.15 reduces acute cerebellum damage after germinal matrix-intraventricular hemorrhage of the preterm newborn\" [Biomed. Pharmacother. 180 (2024) 117586]","authors":"Isabel Atienza-Navarro, Angel del Marco, Maria de los Angeles Garcia-Perez, Alvaro Raya-Marin, Carmen Gil, Ana Martinez, Isabel Benavente-Fernandez, Simon Lubian-Lopez, Monica Garcia-Alloza","doi":"10.1016/j.biopha.2026.119512","DOIUrl":"10.1016/j.biopha.2026.119512","url":null,"abstract":"","PeriodicalId":8966,"journal":{"name":"Biomedicine & Pharmacotherapy","volume":"200 ","pages":"Article 119512"},"PeriodicalIF":7.5,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147960631","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Corrigendum to “Photodynamic therapy offers a novel approach to managing miltefosine-resistant cutaneous leishmaniasis” [Biomed. Pharmacother. 177 (2024) 116881]","authors":"Fernanda V. Cabral, Mina Riahi, Saydulla Persheyev, Cheng Lian, Mauro Cortez, Ifor D.W. Samuel, Martha S. Ribeiro","doi":"10.1016/j.biopha.2026.119495","DOIUrl":"10.1016/j.biopha.2026.119495","url":null,"abstract":"","PeriodicalId":8966,"journal":{"name":"Biomedicine & Pharmacotherapy","volume":"200 ","pages":"Article 119495"},"PeriodicalIF":7.5,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147990399","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Corrigendum to “Dose-dependent effects of methylene blue on hemodynamics, cytokines, oxidative stress, and organ dysfunction in a rat model of CLP-induced sepsis: An experimental study” [Biomed. Pharmacother. 199 (2026) 119469]","authors":"Özhan Özcan, Şeyma Şimşirgil Kara, Bilge Bal Özkaptan, Kıvanç Öncü, Mustafa Harun Şahin, H. Demet Cabar, Özgür Korhan Tunçel, Dilek Sağır","doi":"10.1016/j.biopha.2026.119540","DOIUrl":"10.1016/j.biopha.2026.119540","url":null,"abstract":"","PeriodicalId":8966,"journal":{"name":"Biomedicine & Pharmacotherapy","volume":"200 ","pages":"Article 119540"},"PeriodicalIF":7.5,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147977520","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Corrigendum “Protective effects of E-CG-01 (3,4-Lacto cycloastragenol) against bleomycin-induced lung fibrosis in C57BL/6 mice” [Biomed. Pharmacother. 177 (2024) 117016]","authors":"Kubilay Dogan Kilic, Derya Erisik, Dilek Taskiran, Kutsal Turhan, Timur Kose, Emel Oyku Cetin, Aylin Sendemi̇r, Yiğit Uyanikgil","doi":"10.1016/j.biopha.2026.119494","DOIUrl":"10.1016/j.biopha.2026.119494","url":null,"abstract":"","PeriodicalId":8966,"journal":{"name":"Biomedicine & Pharmacotherapy","volume":"200 ","pages":"Article 119494"},"PeriodicalIF":7.5,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148045228","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Corrigendum to “The protective effect of silver nanoparticles' on epithelial cornea cells against ultraviolet is accompanied by changes in calcium homeostasis and a decrease of the P2X7 and P2Y2 receptors” [Biomed. Pharmacother. 174 (2024) 116090]","authors":"Patryk Krzemiński, Irena Misiewicz-Krzemińska, Marta Grodzik, Irena Padzińska-Pruszyńska, Paulina Kucharzewska, Agnieszka Ostrowska, Ewa Sawosz, Paweł Pomorski","doi":"10.1016/j.biopha.2026.119603","DOIUrl":"10.1016/j.biopha.2026.119603","url":null,"abstract":"","PeriodicalId":8966,"journal":{"name":"Biomedicine & Pharmacotherapy","volume":"200 ","pages":"Article 119603"},"PeriodicalIF":7.5,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148159567","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Corrigendum to “Sustained intravitreal dissolution and kinase inhibition by an inhibitory cGMP analogue after its injection as a suspension of a poorly soluble salt” [Biomed. Pharmacother. 199 (2026) 119387]","authors":"Eetu Valkama, Elisa Toropainen, Simar Pal Singh, Annika Valtari, Ali Koskela, Arto Merivaara, Oswaldo Perez, Marika Ruponen, John Groten, Nicolaas Schipper, Arto Urtti, Kati-Sisko Vellonen, Tatu Lajunen, Jooseppi Puranen","doi":"10.1016/j.biopha.2026.119601","DOIUrl":"10.1016/j.biopha.2026.119601","url":null,"abstract":"","PeriodicalId":8966,"journal":{"name":"Biomedicine & Pharmacotherapy","volume":"200 ","pages":"Article 119601"},"PeriodicalIF":7.5,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148152496","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Targeting ER stress in adrenocortical carcinoma: Celastrol as a novel therapeutic candidate","authors":"Aurora Schiavon ,&nbsp;Carlotta Evaristo ,&nbsp;Laura Saba ,&nbsp;Jessica Petiti ,&nbsp;Ymera Pignochino ,&nbsp;Soraya Puglisi ,&nbsp;Paola Perotti ,&nbsp;Erika Messina ,&nbsp;Claudia Giachino ,&nbsp;Massimo Terzolo ,&nbsp;Marco Lo Iacono","doi":"10.1016/j.biopha.2026.119156","DOIUrl":"10.1016/j.biopha.2026.119156","url":null,"abstract":"<div><h3>Background</h3><div>Adrenocortical carcinoma (ACC) is a rare, aggressive malignancy with limited treatment options. Mitotane, the only approved drug, has modest efficacy and frequent adverse effects, underscoring the urgent need for new therapeutic approaches. Celastrol, a triterpene compound derived from traditional Chinese medicine, exhibits anti-inflammatory activity and broad anti-tumor effects, including sensitization of cancer cells to chemo- and radiotherapy.</div></div><div><h3>Purpose</h3><div>In this study, we investigated for the first time the anti-cancer potential of celastrol in the ACC H295R cell line.</div></div><div><h3>Methods</h3><div>Using different in vitro biomolecular technologies and biochemical/biophysical experiments, we evaluated celastrol’s effect on ACC cells.</div></div><div><h3>Results</h3><div>Celastrol induced apoptosis in ACC cells and demonstrated efficacy not only in 2D monolayer cultures but also in 3D spheroid models. Importantly, it inhibited spheroid growth and disrupted pre-formed spheroids, highlighting its activity in tumor-like structures. Mechanistic analyses suggested that celastrol triggers apoptosis through induction of endoplasmic reticulum (ER) stress and oxidative stress. These findings parallel our previous observations with mitotane, which also activates the ER stress pathway via the ATF4-ATF3 axis. This partial convergence points to ER stress induction as a potential therapeutic target in ACC.</div></div><div><h3>Conclusion</h3><div>identifying agents capable of complementing or replacing standard therapy remains a central challenge in ACC research. Our findings suggest that celastrol is a potent bioactive compound with activity against both monolayer and 3D ACC models, offering potential translational relevance. By elucidating ER stress as a shared mechanism between celastrol and mitotane, our work supports further exploration of this pathway as a strategy to potentially improve therapeutic outcomes in ACC patients.</div></div>","PeriodicalId":8966,"journal":{"name":"Biomedicine & Pharmacotherapy","volume":"197 ","pages":"Article 119156"},"PeriodicalIF":7.5,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147313417","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Corrigendum \"chemical profiling and investigation of molecular mechanisms underlying anti-hepatocellular carcinoma activity of extracts from Polygonum perfoliatum L.\" [Biomedicine & Pharmacotherapy 166 (2023) 115315]","authors":"Xiaolong Tang ,&nbsp;Lin Liu ,&nbsp;Yan Li ,&nbsp;Siyu Hao ,&nbsp;Yueshui Zhao ,&nbsp;Xu Wu ,&nbsp;Mingxing Li ,&nbsp;Yu Chen ,&nbsp;Shuai Deng ,&nbsp;Shuang Gou ,&nbsp;Dan Cai ,&nbsp;Meijuan Chen ,&nbsp;Xiaobing Li ,&nbsp;Yuhong Sun ,&nbsp;Li Gu ,&nbsp;Wanping Li ,&nbsp;Fang Wang ,&nbsp;Zhuo Zhang ,&nbsp;Lei Yao ,&nbsp;Jing Shen ,&nbsp;Fukuan Du","doi":"10.1016/j.biopha.2026.119171","DOIUrl":"10.1016/j.biopha.2026.119171","url":null,"abstract":"","PeriodicalId":8966,"journal":{"name":"Biomedicine & Pharmacotherapy","volume":"197 ","pages":"Article 119171"},"PeriodicalIF":7.5,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147322665","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Corrigendum to “Investigating neuroprotective roles of Bacopa monnieri extracts: Mechanistic insights and therapeutic implications” [Biomed. Pharmacother. 153 (2022) 113469]","authors":"Urooj Fatima ,&nbsp;Sonam Roy ,&nbsp;Shahnawaz Ahmad ,&nbsp;Lamya Ahmed Al-Keridis ,&nbsp;Nawaf Alshammari ,&nbsp;Mohd Adnan ,&nbsp;Asimul Islam ,&nbsp;Md. Imtaiyaz Hassan","doi":"10.1016/j.biopha.2026.119172","DOIUrl":"10.1016/j.biopha.2026.119172","url":null,"abstract":"","PeriodicalId":8966,"journal":{"name":"Biomedicine & Pharmacotherapy","volume":"197 ","pages":"Article 119172"},"PeriodicalIF":7.5,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147349886","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Retraction notice to “Non-coding RNA-mediated modulation of ferroptosis in cardiovascular diseases” [Biomedicine & Pharmacotherapy 164 (2023) 114993]","authors":"Ying Liu ,&nbsp;Wei Ding ,&nbsp;Jianxun Wang ,&nbsp;Xiang Ao ,&nbsp;Junqiang Xue","doi":"10.1016/j.biopha.2026.119192","DOIUrl":"10.1016/j.biopha.2026.119192","url":null,"abstract":"","PeriodicalId":8966,"journal":{"name":"Biomedicine & Pharmacotherapy","volume":"197 ","pages":"Article 119192"},"PeriodicalIF":7.5,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147379830","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}