Journal of biomedical graphics and computing最新文献

{"title":"Reproducibility and variability in the assessment of color-coded tissue velocity imaging of the fetal myocardium","authors":"N. Elmstedt, B. Lind, K. Ferm-Widlund, M. Westgren, L. Brodin","doi":"10.5430/JBGC.V3N2P16","DOIUrl":"https://doi.org/10.5430/JBGC.V3N2P16","url":null,"abstract":"Objective : The introduction of color-coded tissue velocity imaging (TVI) in fetal medicine is quite recent, and as this method is presently evaluated and developed in regard to diagnostic precision it is of outmost importance to evaluate the reproducibility for adequate clinical use. In this study, reproducibility and intra- and inter-observer variability was assessed for offline analysis as well as echocardiography investigations. Also, we evaluated the importance of exact placement of the region of interest (ROI). Methods : TVI recordings from 21 fetuses, at a gestational age of 27 to 41 weeks, were acquired at 208-239 frames/s for subsequent offline analysis. All recordings were performed with the transducer positioned to provide an apical four-chamber view and the myocardial velocity data was obtained from basal inferoseptum. The data set was analyzed according to Bland-Altman and reproducibility was expressed as the standard error of a single determination, estimated from duplicate determinations in percentage of the total. Results : The variation of reproducibility for the echocardiography investigation ranged from 2.0% to 9.8%. The duration of left ventricular ejection, and the peak velocities of early diastolic filling and atrial contraction being the most robust events measured. The variation of inter-observer variability for the echocardiography investigation ranged from 1.5% to 8.4%, and the variation of intra- and inter-observer variability for the offline analysis ranged from 1.2% to 10.4%. Least robust were the events of shortest duration, including isovolumetric contraction and relaxation. Conclusion : We believe that TVI measurements of the fetal myocardium could be performed in the clinical routine with acceptable reproducibility.","PeriodicalId":89580,"journal":{"name":"Journal of biomedical graphics and computing","volume":"3 1","pages":"16"},"PeriodicalIF":0.0,"publicationDate":"2013-02-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.5430/JBGC.V3N2P16","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71213746","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Transrectal ultrasonography can safely replace cysto- graphy in assessing vesico-urethral anastomosis after radical prostatectomy","authors":"G. Perugia, M. Ciccariello, H. Shahabadi, A. Chinazzi, E. Corongiu, G. Borgoni, M. Liberti","doi":"10.5430/JBGC.V3N2P1","DOIUrl":"https://doi.org/10.5430/JBGC.V3N2P1","url":null,"abstract":"Objectives : A well performed vesico-urethral anastomosis (VUA) allows an early catheter removal and cystography is mandatory to exclude urinary extravasation. Aim of the study is to investigate whether transrectal ultrasonography (TRUS) is as reliable as cystography in detecting anastomotic leakage after radical retropubic prostatectomy (RRP) in order to avoid the use of X-rays. Methods : 50 patients (pts) underwent RRP. VUA integrity was assessed 7 days after surgery by cystography and subsequently by TRUS to assess the patency of VUA. Patients who showed extravasation at the cystogram underwent ultrasonography in order to evaluate the leakage shown with cystography. Results : Catheter was removed after 7 days in all patiens except 2 pts (4%) showed extravasation at the cystography that was exactly detected at the TRUS investigation, therefore the catheter was maintained for another week. TRUS investigation, performed after cystography, also revealed the presence of a lymphocele and a retropubic hematoma, in two different patients, both completely asymptomatic and misdiagnosed at the cystography. Conclusions: Urinary leakage in the first days after RRP can be frequent and cystography is mandatory to assess VUA integrity, when early catheter removal is planned. TRUS as an alternative investigation technique to cystography, showed a high sensitivity and specificity in detecting extravasation and was also able to diagnose complications related to RRP that cystography didn't show.","PeriodicalId":89580,"journal":{"name":"Journal of biomedical graphics and computing","volume":"3 1","pages":"1"},"PeriodicalIF":0.0,"publicationDate":"2013-02-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.5430/JBGC.V3N2P1","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71213826","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cystitis cystica mimicking as bladder tumour","authors":"S. Bapat, L. Shah, A. Talaulikar, V. Kothari, N. Shah, D. Shah, V. Deshmukh","doi":"10.5430/JBGC.V3N1P96","DOIUrl":"https://doi.org/10.5430/JBGC.V3N1P96","url":null,"abstract":"Objective: We present our experience of managing six cases of cystitis cystica, which mimicked a bladder tumour. Materials and Methods: Six cases of cystitis cystica were diagnosed over a period of five years (2005-2011). Age varied from 26 to 54 years of which four patients were male and two were females. All of them presented with lower urinary tract symptoms (LUTS), urinary tract infection (UTI) in 3 patients and mild intermittent hematuria in 2 patients. Clinical examination and routine laboratory tests were normal except for presence of leucocytes and blood in urine. Ultrasound (USG) revealed thickened bladder wall with polypoidal lesions suspicious of malignancy. Urinary cytology was negative for malignant cells. Cystoscopy revealed multiple papillary lesions arising from the bladder neck and trigone. There was conspicuous absence of a blood vessel core in the centre of the papillary fronds. Transurethral biopsy of the bladder lesion revealed cystitis cystica with no evidence of malignancy. Four out of six patients responded well to conservative treatment with long-term oral antibiotics as per the culture and sensitivity reports. Transurethral resection was required in only two patients due to lesions causing obstructive symptoms.  Patients were followed up with history and clinical examination, urinary cytology and ultrasonographic monitoring of the lesions. Results: Of the six cases TUR, resection was required in only 2 patients with obstructing lesions and remaining 4 were managed conservatively. Conclusion: Cystitis cystica is a rare benign condition that can mimic bladder tumour. Cystoscopic appearance is typical and biopsy confirms the diagnosis. Treatment is usually conservative. TUR resection is required in selected cases. Long-term follow up is essential, as cystitis cystica is a premalignant disease of the urinary bladder.","PeriodicalId":89580,"journal":{"name":"Journal of biomedical graphics and computing","volume":"33 1","pages":"96"},"PeriodicalIF":0.0,"publicationDate":"2012-12-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.5430/JBGC.V3N1P96","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71213243","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessment of indeterminate melanocytic choroidal tumours with optical coherence tomography: A cohort study","authors":"S. Garnier, J. Grange, L. Kodjikian","doi":"10.5430/JBGC.V3N1P75","DOIUrl":"https://doi.org/10.5430/JBGC.V3N1P75","url":null,"abstract":"Background: It is difficult to differentiate large choroidal naevi from small melanomas. The management of patients with such ‘indeterminate melanocytic tumours’ is controversial. This is because over-treatment of naevi can cause unnecessary visual loss whereas delayed treatment of melanoma may have fatal consequences. Several studies have shown that serous retinal detachment overlying an indeterminate melanocytic choroidal tumour predicts growth of these tumours; however, these studies have mostly been based on ophthalmoscopy. Optical coherence tomography (OCT) facilitates the detection of subtle retinal detachment. It is not known, however, whether minimal retinal detachment is clinically relevant. The aim of our study was to evaluate OCT as a tool for predicting growth of indeterminate melanocytic choroidal tumours. Methods: Forty-five patients with a recently-detected, indeterminate melanocytic choroidal tumour were examined with OCT and the findings were correlated with subsequent tumour growth. Results: After a mean follow-up of 15 months, 9 of 17 tumours with SRF showed growth as compared to 1 out of 28 tumours without SRF. Tumours with SRF increased in thickness by an average of +0.26mm [95% confidence interval (CI): -0.06 to +0.57] as compared to a mean decrease of -0.12mm [95% CI : -0.22 to -0.03] in tumours without SRF. Of the eight tumours requiring treatment because of observed growth, seven showed overlying SRF as compared to none of the tumours without SRF. Conclusions: OCT is useful in predicting growth of indeterminate melanocytic choroidal tumours.","PeriodicalId":89580,"journal":{"name":"Journal of biomedical graphics and computing","volume":"3 1","pages":"75"},"PeriodicalIF":0.0,"publicationDate":"2012-12-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.5430/JBGC.V3N1P75","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71213050","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Primary classical seminoma of testis with foci of signet-ring-cell morphology: A case report and review of the literature including ESMO guidelines on management of seminoma of testis","authors":"A. Venyo, Kweku Baiden-Amissah","doi":"10.5430/JBGC.V3N1P81","DOIUrl":"https://doi.org/10.5430/JBGC.V3N1P81","url":null,"abstract":"Background: Signet-ring-cell carcinoma is a rare variant of mucinous adenocarcinoma. Only about 3 cases of primary testicular cancer with signet-ring-cell morphology have been reported so far in the literature. There is lack of knowledge regarding the biological behaviour of this type of tumour affecting the testis. Seminoma of the testis is quite common and its biological behaviour is well known. When a classical seminoma of the testis is found to be contemporaneously associated with signet-ring-cell morphology, in view of the absence of any detailed literature on this rare clinical entity, the biological behaviour of such a tumour cannot be predicted. Objectives: To report a case of Classical Seminoma of the testis interspersed with seminoma cells with signet-ring morphology. To review the literature on signet-ring-cell carcinomas including carcinomas of testis with signet- ring- cell morphology. To review the ESMO guidelines on management of seminoma of testis Results: A 32-year-old man came for urology consultation 11 months after he had noticed a lump in his left testis. He had a family history of testicular cancer. A hard lump clinically suspicious of a tumour was palpable in the lower pole of his left testis. The right testis felt normal on palpation. His serum Beta HCG level was raised. He had ultra-sound scan of testis which showed bilateral microlithiasis with a tumour in the left testis but no tumour in the right testis. He underwent left radical orchidectomy and histology of the testicular tumour revealed a classical testicular seminoma with foci of signet-ring -cell morphology based upon haematoxylin and eosin staining as well as positive immunostaining for CD117 and OCT 3 / 4. Literature review revealed paucity of literature on testicular tumours with signet-ring-cell morphology. Conclusions: There is paucity of literature on primary testicular tumours with signet-ring-cell morphology. In order to establish the biological behaviour of such tumours we would encourage pathologists and urologists to report cases of testicular tumours associated with signet-ring-cell morphology together with the long term biological behaviour of such tumours. They should also report on the percentage of testicular tumours that have signet–ring-cell morphology and their distribution whether patchy or diffuse. Ultrasound-scan of testis was required to establish the diagnosis of testicular cancer in the patient. Ultrasound-scan of testis is useful in the investigation of a testicular lump. Ultrasound and CT scans are also useful for the follow-up of patients with testicular cancer and microlithiasis.","PeriodicalId":89580,"journal":{"name":"Journal of biomedical graphics and computing","volume":"3 1","pages":"81"},"PeriodicalIF":0.0,"publicationDate":"2012-12-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.5430/JBGC.V3N1P81","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71213168","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The contribution of magnetic resonance spectroscopy as biomarker in Alzheimer's disease","authors":"P. Modrego","doi":"10.5430/JBGC.V3N1P66","DOIUrl":"https://doi.org/10.5430/JBGC.V3N1P66","url":null,"abstract":"The use of biomarkers is growing in the early detection of Alzheimer’s disease (AD). Although some biomarkers such as medial temporal lobe volumetry, amyloid Positron Emision Tomography (PET), and Aβ42 in CSF are being widely used, there is no clear consensus about the best biomarker to be used in each phase of the disease. Magnetic Resonance Spectroscopy (MRS) of the brain is less known as biomarker but has proven useful according to cross-sectional and longitudinal studies. This technique measures metabolite levels that reflect the degree of pathology in the brain. N-acetyl aspartate (NAA), a marker of neuronal density, decreases and Myo-inositol, a marker of glial proliferation, increases as the disease progresses. Decreased NAA levels have been detected in the prodromal phases of AD and even in presymptomatic stages in carriers of tau and amyloid protein mutations. Longitudinal studies have demonstrated  good correlation between NAA levels and progression of AD, even in spite of treatment with cholinesterase inhibitors. From clinical trials we have learned that the current therapies have a modest effect on AD progression and that they do not have neuroprotective effects. This modest effect is reflected in the modest or null changes in metabolite levels in clinical trials using MRS as biomarker.","PeriodicalId":89580,"journal":{"name":"Journal of biomedical graphics and computing","volume":"3 1","pages":"66"},"PeriodicalIF":0.0,"publicationDate":"2012-12-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71213318","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Massive pulmonary embolism with ST-elevation in the inferior leads and other interesting ECG findings","authors":"S. Alsidawi, Mouhammad Abdalla, T. Helmy","doi":"10.5430/JBGC.V3N1P43","DOIUrl":"https://doi.org/10.5430/JBGC.V3N1P43","url":null,"abstract":"Introduction: Pulmonary embolism is associated with many ECG findings, most of which are non-specific and most can be explained by the sudden severe increase in the right ventricular afterload leading to dysfunction, hypoperfusion, dilation and in rare very severe cases to ischemic injury. Many case reports described patients presenting with massive pulmonary embolism and very rare atypical ECG findings especially ST-segment elevation in the anteroseptal leads (V1-V4). Case presentation: We present a case of a 73-year old African American male who suffered from a massive pulmonary embolism with interesting ECG findings mainly ST-segment elevation in the inferior leads mimicking Inferior wall myocardial infarction. To our knowledge, this is the first case of ST-elevation in the inferior leads in the setting of a massive PE. Conclusion: The most likely explanation to the case is that the associated cardiac injury is multifactorial. Severe right ventricular dilation with significant increase in wall tension and oxygen consumption, sudden coronary hypoperfusion caused by the sudden drop in the right and left ventricular output, hypoxia caused by the massive PE and finally possible coronary spasm caused by hypoxia and increased right heart pressure might all have contributed to inducing the acute right ventricular ischemia which showed as ST-segment elevation in the inferior leads and an elevation in cardiac enzymes.","PeriodicalId":89580,"journal":{"name":"Journal of biomedical graphics and computing","volume":"3 1","pages":"43"},"PeriodicalIF":0.0,"publicationDate":"2012-12-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.5430/JBGC.V3N1P43","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71213322","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A fully automated system for quantification of knee bone marrow lesions using MRI and the osteoarthritis initiative cohort","authors":"P. Dodin, F. Abram, J. Pelletier, J. Martel-Pelletier","doi":"10.5430/JBGC.V3N1P51","DOIUrl":"https://doi.org/10.5430/JBGC.V3N1P51","url":null,"abstract":"Background/Objective: Bone marrow lesions (BMLs) have been associated with pain and cartilage degeneration in patients with knee osteoarthritis; their specific detection and quantification is therefore of primary importance. This study aimed at developing a fully automated quantitative BML assessment technology for human knee osteoarthritis using magnetic resonance images (MRI) and two sequences, a T1/T2*-weighted gradient echo (DESS) and a water-sensitive intermediate-weighted turbo spin echo (IW-TSE). Methods: The automated BML quantification first characterizes the bone and cartilage domains in the DESS sequence using our already published automated technology, then proceeds to the BML quantification which was developed as a four-stage process: selection of structured bright areas corresponding to BMLs, geometric filtering of unrelated structures, segmentation of the BML, and quantification of BML proportion within bone regions. For the IW-TSE sequence, the first step consists of the transfer of the bone and cartilage objects from the DESS to the IW-TSE images, followed by the BML detection and quantification as for the DESS. Validation was performed on 154 OA patients from a subset of the Osteoarthritis Initiative (OAI) cohort (public data sets) in which BML manual segmentation intra- and inter-reader reliability was done for each sequence (DESS and IW-TSE) using the intraclass correlation (ICC). BML comparison between the newly developed automated method with a manual segmentation was performed with ICC for the proportion of BML and Dice similarity coefficient (DSC) for BML localization and geometric extent. Finally, comparisons between the DESS and the IW-TSE sequences were performed for BML incidence and proportion. Results: Excellent to very good correlations were obtained for both MRI sequences for intra- and inter-reader reliability of the manual BML segmentation. Comparison between the developed automated method and the manual BML segment- ation showed excellent to very good correlations in the global knee and regions (ICC=0.99 to 0.68 for DESS and 0.99 to 0.77 for IW-TSE sequences) as well as very good to good similarity for the BML geometrical agreement (DESS, 0.60 to 0.41; IW-TSE, 0.59 to 0.41). Data revealed greater BML incidence at the sites of high articular constraints: lateral femoropatellar and medial tibiofemoral articulation. Average BML proportion revealed a scaling factor of about 4.5-fold more for the IW-TSE compared to the DESS. Conclusions: The newly developed fully automated MRI based BML assessment technology not only detects the absence/ presence of these pathological signals in the osteoarthritic human knee, but also provides accurate quantitative assessment of BMLs in the global knee and knee regions. Such automated system will enable large scale studies to be conducted within shorter durations, as well as increase stability of the reading.","PeriodicalId":89580,"journal":{"name":"Journal of biomedical graphics and computing","volume":"226 1","pages":"51"},"PeriodicalIF":0.0,"publicationDate":"2012-12-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.5430/JBGC.V3N1P51","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71213342","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Regional differences in hepatic fat fractions in over- weight children and adolescents observed by 3T 1H-MR spectroscopy","authors":"E. Chabanova, D. Bille, E. Thisted, J. Holm, H. Thomsen","doi":"10.5430/JBGC.V3N1P35","DOIUrl":"https://doi.org/10.5430/JBGC.V3N1P35","url":null,"abstract":"Background : Proton MR Spectroscopy ( 1 H MRS) can be used to measure hepatic fat fractions (HFF) in liver cells for assessment of non-alcoholic fatty liver disease (NAFLD). The measurement is typically performed in a single volume. For correct diagnosis it is important to know variability of HFF within liver. The purpose of this study was to investigate regional differences in HFF in a large group of overweight and obese children and adolescents using 1H MRS at 3T. Methods: The study included 175 consecutive children and adolescents from 7 to 18 years old with a body mass index above the 97th percentile according to age and gender. 1 H MRS was performed at 3.0T using a point resolved spectroscopy sequence in two 11mmx11mmx11mm volumes positioned in different parts of the right liver lobe. Results: Up to 12% difference in HFF between the two volumes was observed: the regional differences in HFF are below 1% for patients with HFF under 3%; patients with HFF between 3% and 20% have regional differences in HFF up to 5%; patients with HFF over 20% have regional differences in HFF up to 12%. Conclusions: 1H MRS diagnosis and severity assessment of NAFLD in overweight and obese children and adolescents should take up to 12% regional differences in hepatic fat fractions into account.","PeriodicalId":89580,"journal":{"name":"Journal of biomedical graphics and computing","volume":"3 1","pages":"35"},"PeriodicalIF":0.0,"publicationDate":"2012-12-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.5430/JBGC.V3N1P35","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71213154","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Non-uniform illumination correction in infrared images based on a modified fuzzy c-means algorithm","authors":"M. Vlachos, E. Dermatas","doi":"10.5430/JBGC.V3N1P6","DOIUrl":"https://doi.org/10.5430/JBGC.V3N1P6","url":null,"abstract":"The correction of non-uniform illumination and the elimination of shading artifacts is an important preprocessing task used in a great number of image processing applications such as segmentation, registration or quantitative analysis. Although, a careful and accurate set up of the image acquisition system may degrade the importance of a brightness normalization algorithm, non-uniform illumination appears due to the interaction of objects and light on the scene requires retrospective shading correction. The image formation process and the corresponding shading effects are described by a linear image formation model, which consists of a multiplicative and an additive shading component. In this paper a novel brightness normalization method is proposed to eliminate the non-uniform illumination effects. The method is based on the application of a fuzzy c-means algorithm (FCM) only on the background part of the acquired image, where the objective function is modified to take into account local information of each pixel in the estimation of the multiplicative and the additive shading components. The modified FCM algorithm is iterative, as the standard FCM, and at each iteration the multiplicative and the additive shading components are re-estimated based on the cluster centers and the membership of each pixel in a specific cluster. Brightness correction is performed by the inverse of the image formation model after FCM convergence. Experiments were conducted in a database of both real and artificial infrared images. The experimental results show that the proposed method decreases significantly the non-uniform illumination effects and does not introduce brightness variations if the background is uniform.","PeriodicalId":89580,"journal":{"name":"Journal of biomedical graphics and computing","volume":"3 1","pages":"6"},"PeriodicalIF":0.0,"publicationDate":"2012-11-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.5430/JBGC.V3N1P6","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71213277","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}