Journal of Bangladesh College of Physicians & Surgeons最新文献

{"title":"Altemeier’s Procedure, an Easy Solution for Rectal Prolapse","authors":"M. Khalil, A. Alam, Sharker Kamrun Jahan, Abu Zaffor Saleh","doi":"10.3329/jbcps.v40i4.61878","DOIUrl":"https://doi.org/10.3329/jbcps.v40i4.61878","url":null,"abstract":"Introduction: Rectal prolapse is an embarrassing clinical condition. Most of the time patients get emergency hospital admission. Full thickness rectal prolapse demands surgical treatment. Many surgical procedures and techniques were described but none is adopted as standard. It is challenging to choose appropriate surgical procedure in the emergency situations as many patients come after trial of reduction and maltreatment. We have treated 64 patients of full thickness rectal prolapse by Altemeier’s procedure in emergency admissions. This study was designed to observe the outcomes of Altemeier’s procedure (perineal proctosigmoidectomy) in full thickness rectal prolapse as emergency surgery.\u0000Methods: This prospective study was done in Dhaka Medical College Hospital and Cumilla Medical College Hospital over the period of January 2013 to July 2018. Total 64 patients were included in this study. Alteimer’s procedure was done in all patients. Patients were followed up on 2 weeks, 1 month, 3months, 6 months and 1 year. Patients were evaluated by complain of pain, per rectal bleeding, mucous discharge, bowel movement and incontinence. Postoperative data was collected and evaluated.\u0000Results: Reduction was achieved in all patients and they were satisfied about their prolapse correction. Two patients needed blood transfusion and laparotomy. Anastomotic disruption and bleeding from the mesenteric vessels were found on laparotomy. All patients had improved evacuation as assessed by history of satisfactory evacuation. No recurrence was reported during the follow up period. Gas and liquid incontinence were noted in 3 patients who improved with sphincter exercise within 3 months.\u0000Conclusion: In our series, we found Altemeier’s procedure is safe, effective for complete rectal prolapse specially in emergency situation and can be done under regional anesthesia.\u0000J Bangladesh Coll Phys Surg 2022; 40: 229-232","PeriodicalId":89579,"journal":{"name":"Journal of Bangladesh College of Physicians & Surgeons","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43330007","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Vitamin D Deficiency in Infertile Males with Oligospermia: A Cross-sectional Comparative Study","authors":"F. Islam, Shakeela Ishrat, P. Fatima, Shaabati Dey, R. Ara, E. R. Nandi","doi":"10.3329/jbcps.v40i4.61877","DOIUrl":"https://doi.org/10.3329/jbcps.v40i4.61877","url":null,"abstract":"Introduction: The male factor responsible for infertility includes oligospermia. According to WHO criteria, oligospermia is sperm concentration less than 15 million per millilitre of semen. Vitamin D is a steroid hormone synthesized in the skin and derived from the diet. A serum level less than 20 ng/dl is regarded as vitamin D deficiency. The deficiency of vitamin D has been linked to many reproductive disorders. This study was designed to analyze the association between serum vitamin D level and oligospermia.\u0000Methods: A cross-sectional comparative study was conducted in the Department of Reproductive Endocrinology and infertility of Bangabandhu Sheikh Mujib Medical University, Dhaka, during the period of July 2018 to June 2019. There are 157 infertile males with oligospermia in one group and 157 infertile males with normozoospermia in another group. A base line semen analysis for evaluation of male infertility was done, and serum vitamin D level was estimated.\u0000Results: The mean vitamin D level is 16.75+5.75 ng/ml in males with oligospermia and 19.83+5.33 ng /ml in males with normozoospermia. By the threshold defined, all the infertile males are deficient in vitamin D. The difference between the circulating levels of vitamin D in the two groups is statistically significant (p<0.05). VitaminD deficiency is 4.25 times more in infertile males with oligospermia than in males with normozoospermia.\u0000Conclusion: Vitamin D deficiency is associated with oligospermia in infertile males.\u0000J Bangladesh Coll Phys Surg 2022; 40: 253-256","PeriodicalId":89579,"journal":{"name":"Journal of Bangladesh College of Physicians & Surgeons","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47700520","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Reliability Assessment of Bangla Version of the Shoulder Pain and Disability Index (SPADI)","authors":"M. Yousuf","doi":"10.3329/jbcps.v40i3.60295","DOIUrl":"https://doi.org/10.3329/jbcps.v40i3.60295","url":null,"abstract":"Abstract not available\u0000J Bangladesh Coll Phys Surg 2022; 40: 145","PeriodicalId":89579,"journal":{"name":"Journal of Bangladesh College of Physicians & Surgeons","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-07-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43618307","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Vitamin - D level and severity of COVID-19 among the Admitted Patients in a COVID Dedicated Tertiary Care Hospital - An Prospective Study","authors":"Md. Titu Miah, R. Yasmin, M. Haque, Nazim Al Azad, R. Parveen, Nandita Paul, R. B. Habib, S. Deb, Md. Ahsanul Haque, Tushar Kanti Barman","doi":"10.3329/jbcps.v40i3.60302","DOIUrl":"https://doi.org/10.3329/jbcps.v40i3.60302","url":null,"abstract":"Background The impact of vitamin D on COVID-19 infection has been much discussed recently. Our aim was to evaluate the association between baseline serum 25(OH)D with severity of COVID-19.\u0000Method This was an prospective study, where 174 COVID- 19 in-patients of an academic hospital in an urban setting were enrolled from Aug, 2020 to Oct, 2020. After detailed clinical history taking and examination, patients were divided into mild, moderate, severe and critical categories. Vitamin D level was measured. Relation between level of vitamin D and disease severity was determined.\u0000Result Mean age of the study population was 52.01 years. 13% mild, 22.99% moderate, 26.44% severe and 3.45% were critical cases. 76% of the patients had vitamin D deficiency. No statistical significance between the level of vitamin D and disease severity was seen (p= 0.430).\u0000Conclusion Our study revealed there is no correlation between vitamin D deficiency and severity of COVID-19.\u0000J Bangladesh Coll Phys Surg 2022; 40: 166-170","PeriodicalId":89579,"journal":{"name":"Journal of Bangladesh College of Physicians & Surgeons","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-07-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47195642","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"POEMS Syndrome in a Patient with Castleman Disease: A Case Report","authors":"A. Nayeem, Gurudas Mandol, Rasheed Imam Zahid, M. Habib, Issa Muhammad Baker, Q. Mohammad","doi":"10.3329/jbcps.v40i3.60308","DOIUrl":"https://doi.org/10.3329/jbcps.v40i3.60308","url":null,"abstract":"POEMS syndrome is a rare multisystem disorder that clinically manifests as a paraneoplastic syndrome and monoclonal plasma cell dyscrasia. Its acronym is derived from its principal characteristics: polyneuropathy, organomegaly, endocrinopathy, M proteins, and skin changes. Here, a case of POEMS syndrome was reported also having features of Castleman disease. A 43-year-old man was admitted with weakness of all four limbs, tingling, heaviness, muscle cramps along with headache for the last 6 months; examination revealed flaccid quadriparesis, generalized areflexia with flexor plantar response, papilloedema, cervical lymphadenopathy, hepatomegaly, tender mass at the left parieto-occipital region, pitting edema and testicular atrophy. Laboratory tests revealed thrombocytosis, high blood sugar, hepatomegaly, lytic lesions at the left parietal bone, pelvis, and intraosseous mass in the Pareto-occipital region; nerve conduction study showed the demyelinating motor neuropathy without conduction block. Intraosseous mass biopsy showed solitary plasmacytoma and immunohistochemical markers positive for CD138 and Ki- 67 MUM-1 and lambda/kappa >10:1, suggesting plasma cell dyscrasia with lambda chain restriction. Biopsy from the cervical lymph node revealed features of Castleman disease. With these clinical and laboratory parameters, this case was finally diagnosed as POEMS syndrome in association with Castleman disease which is a common accompaniment with the syndrome.\u0000J Bangladesh Coll Phys Surg 2022; 40: 204-208","PeriodicalId":89579,"journal":{"name":"Journal of Bangladesh College of Physicians & Surgeons","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-07-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43426510","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Haematopoietic Stem Cell Transplantation: A Single Center Experience of Four Years in Bangladesh","authors":"H. Mahfuz, M. Uddin, Mostafil Karim, M. E. Hossain, A. Islam","doi":"10.3329/jbcps.v40i3.60299","DOIUrl":"https://doi.org/10.3329/jbcps.v40i3.60299","url":null,"abstract":"Background: Haematopoietic stem cell transplantation (HSCT) is the standard consolidation therapy for a variety of malignant and non-malignant diseases in children and adults. Our experience of HSCT in 26 patients with various indications is shared in this article.\u0000Materials and methods: This was a retrospective analysis of first 26 patients who had undergone autologous and allogeneic transplant at our center, with M:F=2.7:1. The mean age for autologous transplant was 45 years (range 23-57 years). The median follow-up period was 23 months 25 days (range 3to 47 months).The data was obtained carefully from medical records of the BMT center. Indications for autologous HSCT were Multiple Myeloma (12 patients), Non- Hodgkin’s lymphoma (7 patients), Hodgkin’s lymphoma (4 patients). Allogeneic HSCT were for Acute Myeloid Leukaemia (3 patients).\u0000Results: The mean time for WBC engraftment was 12 days (range: 9-19 days) and for platelet engraftment was 16 days (range: 11-35 days) in our autologous transplant cases and for allogeneic transplant mean time for WBC engraftment was12 days (range: 11-15 days) and for platelet engraftment was 14 days (range: 12-17 days). Irradiated blood components were given in the pre, peri and post-transplant period to maintain Hb>8 gm/dl and platelet count >20X109/L. Mean single-donor platelet requirement was 4 units (range 1-7), and mean packed red cell requirement was 1.5 units (range 1-6). The post-transplant complications encountered were mucositis, infections and diarrhoea. Oral mucositis was the most common complications. Twenty three (88.46 %) out of our 26 HSCT patients had developed mucositis , among them grade 1 in 5 patients, grade 2 in 11 patients, and grade 3 in 7 patients. There were 21(80.76%) cases of febrile neutropenia. Out of 26 patients 13 (50.0%) bacterial infection were documented with culture positivity. One (3.84%) case of viral infection was documented. Major bacterial infections were culture positive with Pseudomonas, Escherichia coli and Klebsiella followed by other species like acinatobacter, burkholderia and coagulase negative staphylococcus. One case of Cytomegalovirus was noted with significant viral copies that required Ganciclovir. Average duration of hospital stay after autologous HSCT was 23 days (range of 14-54 days) and allogeneic HSCT was 35 days (range of 30-57 days). 19 out of our 23 autologous transplant patients were in complete remission and all 03 cases of allogeneic HSCT were in remission.\u0000Conclusion: We believe our center has made a remarkable progress within short period of time to develop both autologous and allogeneic HSCT and is comparable with nationally and internationally renowned HSCT centers in terms of standard, quality and safety of care, and the ultimate outcomes.\u0000J Bangladesh Coll Phys Surg 2022; 40: 146-152","PeriodicalId":89579,"journal":{"name":"Journal of Bangladesh College of Physicians & Surgeons","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-07-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44162129","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Hemopoietic Stem Cell Transplantation (HSCT) in Bangladesh- Needs Sustained Program and Policy","authors":"M. Khan, M. Akter","doi":"10.3329/jbcps.v40i3.60293","DOIUrl":"https://doi.org/10.3329/jbcps.v40i3.60293","url":null,"abstract":"Abstract not available\u0000J Bangladesh Coll Phys Surg 2022; 40: 138-142","PeriodicalId":89579,"journal":{"name":"Journal of Bangladesh College of Physicians & Surgeons","volume":"35 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-07-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41299972","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Antibody Response to SARS-CoV-2 Infection in Non Vaccinated Health Care Personnel","authors":"P. Khanam, M. S. Hassan, Md. Sohrab Alam, Md. Hasan Belal, Z. Rahman, T. Begum, Akram Khan","doi":"10.3329/jbcps.v40i3.60303","DOIUrl":"https://doi.org/10.3329/jbcps.v40i3.60303","url":null,"abstract":"Background: Antibodies (Abs) are produced by B cells after infection with the SARS/COVID-19 virus. The presence of neutralizing antibody is an indicator of protective immunity for most viral infections. But, we still don’t know how long and how effectively this immune protection will cover. Objectives: This study aimed to estimate the antibodies level in PCR-confirmed COVID-19 subjects in non vaccinated healthcare personnel.\u0000Methods: SARS-CoV-2 specific total Abs (IgG and IgM), IgG of nucleocapsid (N) protein and spike (S) protein levels were estimated using two clinically validated and widely used serological assays, detecting antibodies against the Total Antibody, nucleocapsid(N) and spike(S) proteins.\u0000Results: A total 130 subjects with PCR-confirmed SARSCoV- 2 infection were included in this study and all subjects were symptomatic and blood samples were collected between 3 to 24 weeks. Of all participants, about 52% were female and mean age was 43.2 years. The study found that the Total Abs, IgG of N protein and neutralizing Abs of S protein were developed 100%, 74.6% and 93.8% respectively. The study also found that the IgG titers of the N protein peaked at about 19 weeks after onset and decreased thereafter. The study also found that the neutralizing Abs of S protein were gradually increasing in the second phase of (9wks-19wks) weeks and in the third phase of (19wks -24wks) weeks after disease onset than compared to the first phase of weeks (3wks- 9wks) and it was significant (p<0.001).\u0000Conclusion: The study concluded that the antibodies, total Abs, IgG titer of N protein and neutralizing Abs of S protein were developed 100%, 74.6% and 93.8% respectively. The study also observed that IgG of N protein was decreasing within 19-24 weeks and neutralizing Abs of S protein peaked at 19-24 weeks after the onset of disease.\u0000J Bangladesh Coll Phys Surg 2022; 40: 191-196","PeriodicalId":89579,"journal":{"name":"Journal of Bangladesh College of Physicians & Surgeons","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-07-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47327466","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Phenotype Frequencies of “O” Blood Group (Rh, Kell, and MNS) among Donors in Transfusion Medicine Department of a Training Institute of Bangladesh","authors":"Mohammed Nuruzzaman Bhuiyan, S. Giti, A. Khatun, Md Moshiur Rahman, Md Abdullah Almasud, Sharfin Naher, Bepasha Naznin","doi":"10.3329/jbcps.v40i3.60297","DOIUrl":"https://doi.org/10.3329/jbcps.v40i3.60297","url":null,"abstract":"Background: Although blood transfusions can be lifesaving but it is not without risk. It is a necessity to have knowledge about the red cell antigen phenotype frequencies in a population to provide antigen-negative compatible blood to patients with multiple alloantibodies. This is the first study on extended phenotype of blood group systems in blood donors at AFIP, Dhaka.\u0000Aim: Present study is aimed to determine the antigen frequencies of “O” blood group phenotype among donors at AFIP, Dhaka.\u0000Methods: An observational study was carried out at AFIP, Dhaka from July 2019 to December 2019. A total of 40 “O” blood group donors from blood bank of AFIP were typed for D, C, c, E, e, K, k, M, N and S antigens either by adding antisera to 3-5% of donor RBCs suspension or by using Indirect Antiglobulin Test (IAT) according to manufacturer’s instruction. Coomb’s control cells, positive and negative control cells were used as quality control. Antigens and phenotype frequencies were expressed as percentages.\u0000Results: Forty (40) blood donors belonging to “O” blood group were included for extended phenotyping. D antigen was found in 100% donors, followed by e [42.5%], C [38.13%], c [11.88%], and E [7.5%] with DCe/DCe (R1R1, 55%) as the most common phenotype. k was found to be positive in 72% of donors. In the MNS system, 57.5% donors were typed as M+N+, 32.5% as M+N-, and 10% as M-N+. S-s+ was found amongst donors with 52.5% as the commonest phenotype.\u0000Conclusion: This study was conducted to provide information about the antigen frequency of a common blood group “O” in local donors to provide antigen negative compatible blood units to multi transfused alloimmunized patients. D antigen was found in 100% donors with DCe/DCe (R1R1, 55%) as the most common phenotype.\u0000J Bangladesh Coll Phys Surg 2022; 40: 171-174","PeriodicalId":89579,"journal":{"name":"Journal of Bangladesh College of Physicians & Surgeons","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-07-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45190967","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Outcome of Spontaneous Vaginal Delivery and Elective Induction of Labour in Postdated Pregnancy","authors":"Z. Ferdaushi, Md Zulfikkar Alam, Kamrunnahar Laily","doi":"10.3329/jbcps.v40i3.60300","DOIUrl":"https://doi.org/10.3329/jbcps.v40i3.60300","url":null,"abstract":"Background: Postdated pregnancies are associated with increased perinatal morbidity and mortality. The risk increases when pregnancy continues beyond 41 wks. So, the Induction of labor conducted at or beyond 41 wks could help prevent these complications. But there are certain risks associated with Induction of labor. Again, Induction success varies widely and depends on some modifiable and nonmodifiable factors. Objective: To assess the feto-maternal outcome and analyze the factors affecting the outcome of electively induced labour in postdated pregnancy with a low bishop score compared to spontaneous onset labour in a secondary level hospital.\u0000Materials and methods: Prospective analytical study involving 220 participants divided into induction (study) and spontaneous labour (control) groups. Data collected on socio-demographic data, characteristics of the study population, causes of failed Induction, maternal complications and neonatal outcomes.\u0000Results: Among electively induced postdated pregnancy (study group) vaginal delivery was 45.45% with caesarean section 54.54% compared to 80% and 20% respectively in the spontaneous labour (control group). Cervical dystocia was the commonest indication for caesarean section (P=0.001). Among maternal complications control group had significant perineal lacerations (P=0.016) and study group had a longer duration of hospital stay (P<0.001). The neonatal outcome didn’t show significant difference.\u0000Conclusion: The present study showed routine Induction of labor in prolonged pregnancy may encourage higher caesarean section rate with prolonged hospital stay but judicious Induction even in poor bishop score is not associated with any major feto-maternal complication. Further multicentric study with a larger sample size is recommended.\u0000J Bangladesh Coll Phys Surg 2022; 40: 175-182","PeriodicalId":89579,"journal":{"name":"Journal of Bangladesh College of Physicians & Surgeons","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-07-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46202593","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}