Vitamin - D level and severity of COVID-19 among the Admitted Patients in a COVID Dedicated Tertiary Care Hospital - An Prospective Study

Md. Titu Miah, R. Yasmin, M. Haque, Nazim Al Azad, R. Parveen, Nandita Paul, R. B. Habib, S. Deb, Md. Ahsanul Haque, Tushar Kanti Barman
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Abstract

Background The impact of vitamin D on COVID-19 infection has been much discussed recently. Our aim was to evaluate the association between baseline serum 25(OH)D with severity of COVID-19. Method This was an prospective study, where 174 COVID- 19 in-patients of an academic hospital in an urban setting were enrolled from Aug, 2020 to Oct, 2020. After detailed clinical history taking and examination, patients were divided into mild, moderate, severe and critical categories. Vitamin D level was measured. Relation between level of vitamin D and disease severity was determined. Result Mean age of the study population was 52.01 years. 13% mild, 22.99% moderate, 26.44% severe and 3.45% were critical cases. 76% of the patients had vitamin D deficiency. No statistical significance between the level of vitamin D and disease severity was seen (p= 0.430). Conclusion Our study revealed there is no correlation between vitamin D deficiency and severity of COVID-19. J Bangladesh Coll Phys Surg 2022; 40: 166-170
新冠肺炎专科三级护理医院住院患者维生素D水平和新冠肺炎严重程度的前瞻性研究
背景维生素D对新冠肺炎感染的影响最近被广泛讨论。我们的目的是评估基线血清25(OH)D与COVID-19严重程度之间的关系。在详细的临床病史采集和检查后,将患者分为轻度、中度、重度和危重症。测量维生素D水平。测定了维生素D水平和疾病严重程度之间的关系。结果研究人群的平均年龄为52.01岁。13%为轻度,22.99%为中度,26.44%为重度,3.45%为危重病例。76%的患者存在维生素D缺乏症。维生素D水平与疾病严重程度之间无统计学意义(p=0.430)。结论我们的研究表明,维生素D缺乏与新冠肺炎严重程度之间没有相关性。J Bangladesh Coll Phys Surg 2022;40:166-170
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