Respiratory medicine CME最新文献_第9页

New opacity 新不透明度

Respiratory medicine CME Pub Date : 2010-01-01 DOI: 10.1016/j.rmedc.2009.05.005

Saurabh K. Singh, Deepak K. Pandey, Zuber Ahmad, Rakesh Bhargava

引用次数: 0

Primary Hodgkin's disease of the thymus 原发性胸腺何杰金氏病

Respiratory medicine CME Pub Date : 2010-01-01 DOI: 10.1016/j.rmedc.2009.02.006

Ketata Wajdi, Msaad Sameh, Fouzi Salma, Abid Tarek, Ayadi Hajer, Ayoub Abdelkader

{"title":"Primary Hodgkin's disease of the thymus","authors":"Ketata Wajdi, Msaad Sameh, Fouzi Salma, Abid Tarek, Ayadi Hajer, Ayoub Abdelkader","doi":"10.1016/j.rmedc.2009.02.006","DOIUrl":"https://doi.org/10.1016/j.rmedc.2009.02.006","url":null,"abstract":"<div><p>The thymus is a lymphoid organ located in the antero-superior mediastinum and composed of heterogeneous admixture of lymphoid and epithelial elements. Thymic tumors are dominated by thymoma; lymhomas are uncommon involving the gland secondary to adenopathies. Primary thymic lymphomas are exceptional.</p><p>We report a 25-year-old man referred to us because of chest pain and irritating cough since 2 months. Physical examination was normal and no lymph nodes were palpable. Chest radiography showed an anterior mediastinal mass. Computed tomography (CT) examination of the chest revealed a homogeneous tissular mass occupying the anterior mediastinum in its upper and medium stage, extending to the infundibulum without lymph node enlargement. Thymectomy and wedge were performed via a median sternotomy. Pathologic diagnosis was nodular sclerosis Hodgkin's disease of the thymus. The patient received 6 cycles of ABVD (Adriamycin [doxorubicin], bleomycin, vinblastin and dacarbazine) and mediastinal radiotherapy. Currently, tow years after diagnosis, he is well and free of disease.</p><p>Primary thymic Hodgkin's lymphoma is a rare entity which should be included in the differential diagnosis of anterior mediastinal mass especially in young patients.</p></div>","PeriodicalId":89478,"journal":{"name":"Respiratory medicine CME","volume":"3 1","pages":"Pages 15-17"},"PeriodicalIF":0.0,"publicationDate":"2010-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.rmedc.2009.02.006","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136554836","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Acute Budd–Chiari syndrome caused by tumor thrombus of the inferior vena cava secondary to non-small cell lung cancer 由非小细胞肺癌继发的下腔静脉肿瘤血栓引起的急性布-恰里综合征

Respiratory medicine CME Pub Date : 2010-01-01 DOI: 10.1016/j.rmedc.2009.02.003

Kohei Fujita, Young Hak Kim, Mitsuru Yoshino, Masataka Ichikawa, Tadashi Mio, Michiaki Mishima

{"title":"Acute Budd–Chiari syndrome caused by tumor thrombus of the inferior vena cava secondary to non-small cell lung cancer","authors":"Kohei Fujita, Young Hak Kim, Mitsuru Yoshino, Masataka Ichikawa, Tadashi Mio, Michiaki Mishima","doi":"10.1016/j.rmedc.2009.02.003","DOIUrl":"https://doi.org/10.1016/j.rmedc.2009.02.003","url":null,"abstract":"<div><p>Budd–Chiari syndrome secondary to lung cancer is very rare. The clinical features of this disease have not been well described, as only a few cases have been reported in the past 3 decades. We analyzed 5 such cases, including the present case, and have identified certain features of lung cancer that may play a role in this syndrome. All cases had cancers originating in the right lung, and 4 cases were patients with non-small cell lung cancers. Because of the rapid progression of liver failure, the prognosis for this syndrome is very poor, and the effects of chemotherapy and/or radiotherapy are limited. Recently, however, new treatments, such as stent placement therapy, have been shown to relieve pain and prolong life. We describe a rare case of acute Budd–Chiari syndrome caused by tumor thrombus of the inferior vena cava secondary to lung cancer. In addition, we discuss similar cases reported in the past 3 decades and the effectiveness of stent placement therapy.</p></div>","PeriodicalId":89478,"journal":{"name":"Respiratory medicine CME","volume":"3 1","pages":"Pages 26-28"},"PeriodicalIF":0.0,"publicationDate":"2010-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.rmedc.2009.02.003","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136554839","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

First case of Tsukamurella pulmonis infection in an immunocompetent patient 免疫功能正常患者的第一例肺结核菌感染

Respiratory medicine CME Pub Date : 2010-01-01 DOI: 10.1016/j.rmedc.2009.02.004

Riccardo Inchingolo , Ilaria Nardi , Fabrizio Chiappini , Giuseppe Macis , Fausta Ardito , Michela Sali , Stefania Bani , Giovanni Delogu , Salvatore Valente

引用次数: 3

Pleomorphic carcinoma of the lung: A case report with immunohistochemical studies 肺多形性癌:免疫组织化学研究1例报告

Respiratory medicine CME Pub Date : 2010-01-01 DOI: 10.1016/j.rmedc.2009.10.001

Tadashi Terada

{"title":"Pleomorphic carcinoma of the lung: A case report with immunohistochemical studies","authors":"Tadashi Terada","doi":"10.1016/j.rmedc.2009.10.001","DOIUrl":"https://doi.org/10.1016/j.rmedc.2009.10.001","url":null,"abstract":"<div><p>Because incidence and immunohistochemical features of pulmonary pleomorphic carcinoma (PC) are unclear, the author retrospectively surveyed and re-examined the archival 718 lung malignancy samples in our laboratory. As the results, one case of pulmonary PC was found; thus the incidence of pulmonary PC was 0.14% of all lung malignancies. A 67-year-old woman with asthma was found to have a rapidly growing tumor in the peripheral lower lobe of right lung at a private clinic, and was referred to our hospital. She was a non-smoker. Imaging modalities showed a cystic tumor, and clinical diagnosis was bronchogenic cyst. Right lower lobectomy was performed. The patient is now alive without tumors six years after the operation. Grossly, the tumor was well-defined white tumor with necrosis. The tumor measured 5×4×5cm. Histologically, the tumor was pulmonary PC consisting of malignant spindle and giant cells with focal tubular formations. Necrotic foci and numerous mitotic figures were present. Immunohistochemically, tumor cells were positive for pancytokeratin, high molecular weight cytokeratin (CK), CK5/6, CK7, CK14, CK18, CK19, epithelial membrane antigen, vimentin, p53 protein, surfactant apoprotein A, neuron-specific enolase, lysozyme, Ki-67 (60%), and CD68. Tumor cells were negative for CK20, thyroid transcriptional factor-1, CEA, S100 protein, desmin, α-smooth muscle actin, melanosome, CD34, p63, chromogranin, synaptophysin, CD56, KIT, and platelet-derived growth factor-α. It appeared that the present pulmonary PC is associated with adenocarcinoma or derived from sarcomatous transformation of adenocarcinoma.</p></div>","PeriodicalId":89478,"journal":{"name":"Respiratory medicine CME","volume":"3 4","pages":"Pages 252-256"},"PeriodicalIF":0.0,"publicationDate":"2010-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.rmedc.2009.10.001","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"137088203","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 6

Management of isoniazid-resistant pulmonary tuberculosis in patient with non-functioning bowel on the intensive care unit 重症监护病房中肠功能障碍患者异烟肼耐药肺结核的处理

Respiratory medicine CME Pub Date : 2010-01-01 DOI: 10.1016/j.rmedc.2009.05.002

Katherine M. Coyne, Anton L. Pozniak

引用次数: 0

A case of pulmonary melioidosis 肺类鼻疽1例

Respiratory medicine CME Pub Date : 2010-01-01 DOI: 10.1016/j.rmedc.2009.04.002

J. Lie , S. Maxwell , C. Keeling-Roberts , D. Dev

引用次数: 5

Mature mediastinal teratoma in adult 成人成熟纵隔畸胎瘤

Respiratory medicine CME Pub Date : 2010-01-01 DOI: 10.1016/j.rmedc.2009.02.009

Mohammad Shameem , Syed M. Danish Qaseem , M. Azfar Siddiqui , Naveed Nazir Shah , Asrar Ahmad

引用次数: 10

Recent advances in the diagnosis and treatment of multidrug-resistant tuberculosis 耐多药结核病诊断和治疗的最新进展

Respiratory medicine CME Pub Date : 2010-01-01 DOI: 10.1016/j.rmedc.2010.08.001

Suhail Ahmad, Eiman Mokaddas

{"title":"Recent advances in the diagnosis and treatment of multidrug-resistant tuberculosis","authors":"Suhail Ahmad, Eiman Mokaddas","doi":"10.1016/j.rmedc.2010.08.001","DOIUrl":"https://doi.org/10.1016/j.rmedc.2010.08.001","url":null,"abstract":"<div><p>Tuberculosis (TB) is a major infectious disease killing nearly two million people, mostly in developing countries, every year. The increasing incidence of resistance of <em>Mycobacterium tuberculosis</em> strains to the most-effective (first-line) anti-TB drugs is a major factor contributing to the current TB epidemic. Drug-resistant strains have evolved mainly due to incomplete or improper treatment of TB patients. Resistance of <em>M. tuberculosis</em> to anti-TB drugs is caused by chromosomal mutations in genes encoding drug targets. Multidrug-resistant (resistant at least to rifampin and isoniazid) strains of <em>M. tuberculosis</em> (MDR-TB) evolve due to sequential accumulation of mutations in target genes. Emergence and spreading of MDR-TB strains is hampering efforts for the control and management of TB. The MDR-TB is also threatening World Health Organization’s target of tuberculosis elimination by 2050. Proper management of MDR-TB relies on early recognition of such patients. Several diagnostic methods, both phenotypic and molecular, have been developed recently for rapid identification of MDR-TB strains from suspected patients and some are also suitable for resource-poor countries. Once identified, successful treatment of MDR-TB requires therapy with several effective drugs some of which are highly toxic, less efficacious and expensive. Minimum treatment duration of 18–24 months is also long, making it difficult for health care providers to ensure adherence to treatment. Successful treatment has been achieved by supervised therapy with appropriate drugs at institutions equipped with facilities for culture, drug susceptibility testing of MDR-TB strains to second-line drugs and regular monitoring of patients for adverse drug reactions and bacteriological and clinical improvement.</p></div>","PeriodicalId":89478,"journal":{"name":"Respiratory medicine CME","volume":"3 2","pages":"Pages 51-61"},"PeriodicalIF":0.0,"publicationDate":"2010-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.rmedc.2010.08.001","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"137158519","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Tularemia presenting as a unilateral pleural effusion in a metropolitan city Tularemia在大城市表现为单侧胸腔积液

Respiratory medicine CME Pub Date : 2010-01-01 DOI: 10.1016/j.rmedc.2009.07.005

Kurugundla Navatha, Wei Li , Chukuma Okadigwe , Tom Russi , Rocco Franco

引用次数: 1