{"title":"A case of disseminated blastomycosis presenting as intramuscular abscess","authors":"Siddhartha G. Kapnadak , Ajeet Vinayak","doi":"10.1016/j.rmedc.2010.01.008","DOIUrl":"https://doi.org/10.1016/j.rmedc.2010.01.008","url":null,"abstract":"<div><p>The syndrome of systemic blastomycosis is well described, and has a predilection for involving the lungs, skin, bone, and genitourinary tract. We report a unique case of disseminated disease in an immunocompetent male, in which the presenting symptoms included focal intramuscular involvement. In this case, it was the discovery of the intramuscular abscess that led to the diagnosis of systemic blastomycosis. We provide a general discussion of this endemic mycosis, with focus on disseminated disease and the rare complication of skeletal muscle abscess.</p></div>","PeriodicalId":89478,"journal":{"name":"Respiratory medicine CME","volume":"4 1","pages":"Pages 9-11"},"PeriodicalIF":0.0,"publicationDate":"2011-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.rmedc.2010.01.008","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"92013241","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A 42-year-old man with progressive dyspnea and a rapidly growing mass","authors":"Jinesh P. Mehta, Juan Guardiola","doi":"10.1016/j.rmedc.2011.05.002","DOIUrl":"https://doi.org/10.1016/j.rmedc.2011.05.002","url":null,"abstract":"<div><p>Malignant fibrous histiocytoma (MFH), also known as undifferentiated high grade pleomorphic sarcoma, accounts for 20–24% of all soft tissue sarcomas in the US. Peak incidence is in the fifth and sixth decades of life, with a 2:1 male to female distribution. MFH is usually seen in the soft tissues of the extremity and involvement of the lung is rare. We report a case of pleural MFH in a patient with previous pleuro-pulmonary tuberculosis for which he had a lobectomy.</p></div>","PeriodicalId":89478,"journal":{"name":"Respiratory medicine CME","volume":"4 4","pages":"Pages 151-153"},"PeriodicalIF":0.0,"publicationDate":"2011-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.rmedc.2011.05.002","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"137226495","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ahsan R. Akram , John H. Reid , William Wallace , Simon W. Watkin , Jacqueline F. Faccenda
{"title":"An incidental finding of a lung lesion in a patient with systemic sclerosis","authors":"Ahsan R. Akram , John H. Reid , William Wallace , Simon W. Watkin , Jacqueline F. Faccenda","doi":"10.1016/j.rmedc.2011.03.006","DOIUrl":"https://doi.org/10.1016/j.rmedc.2011.03.006","url":null,"abstract":"<div><p>We present the case of a 59-year-old lady, who was found to have an incidental finding of a lung lesion on a CxR following percutaneous endoscopic gastroscopy tube insertion. Subsequently a computerised tomography scan was performed which suggested primary lung malignancy and CT guided biopsy was arranged. Pathological analysis revealed actinomycosis infection. We discuss the clinical, radiological and pathological findings in actinomycosis and how it can often be mistaken for lung cancer. This may put patients at risk of unnecessary morbidity or even unwarranted surgery and therefore clinicians should have a high clinical suspicion of thoracic actinomycosis, especially if a patient has underlying risk factors, such as aspiration.</p></div>","PeriodicalId":89478,"journal":{"name":"Respiratory medicine CME","volume":"4 4","pages":"Pages 178-180"},"PeriodicalIF":0.0,"publicationDate":"2011-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.rmedc.2011.03.006","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"137225887","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Gert Laekeman , Steven Simoens , Johan Buffels , Michel Gillard , Thibert Robillard , Margherita Strolin Benedetti , Jean-Baptiste Watelet , Georges Liekendael , Liesbet Ghys , Martin Church
{"title":"Continuous versus on-demand pharmacotherapy of allergic rhinitis: Evidence and practice","authors":"Gert Laekeman , Steven Simoens , Johan Buffels , Michel Gillard , Thibert Robillard , Margherita Strolin Benedetti , Jean-Baptiste Watelet , Georges Liekendael , Liesbet Ghys , Martin Church","doi":"10.1016/j.rmedc.2011.04.002","DOIUrl":"https://doi.org/10.1016/j.rmedc.2011.04.002","url":null,"abstract":"<div><p>This review aims to compare continuous with on-demand pharmacotherapy of allergic rhinitis by focusing on pharmacodynamic, pharmacokinetic, safety, effectiveness, cost and cost-effectiveness considerations. A working party of experts reviewed and discussed the literature and guidelines, and conducted a qualitative analysis of the Summary of Product Characteristics of specific medicines. With respect to medicines, the working party limited itself to antihistamines, nasal corticosteroids and leukotriene antagonists. Based on a review of the evidence from a multidisciplinary perspective, this article makes pharmacotherapeutic recommendations that are easy, functional and applicable to daily practice in primary care.</p><p>The pharmacotherapeutic evidence for continuous versus on-demand treatment of allergic rhinitis was limited. Clearly, for corticosteroids, their mechanism of action in allergic rhinitis of reducing allergic inflammation requires continuous therapy at least for the duration of symptoms. For H<sub>1</sub>-antihistamines, some trials suggest that continuous treatment is preferable but more studies are needed to confirm this conclusion. For both H<sub>1</sub>-antihistamines and nasal corticosteroids safety data indicate that continuous treatment may be given without fears of adverse consequences, although a distinction can be made between the first and the second generation antihistamines. With regard to the cost and cost-effectiveness implications of continuous therapy versus on-demand therapy, more studies are necessary before definitive conclusions may be made.</p></div>","PeriodicalId":89478,"journal":{"name":"Respiratory medicine CME","volume":"4 2","pages":"Pages 51-59"},"PeriodicalIF":0.0,"publicationDate":"2011-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.rmedc.2011.04.002","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"137401426","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A very unusual iatrogenic tracheal foreign body","authors":"Oguz Uzun, Nejat Altintas","doi":"10.1016/j.rmedc.2010.10.003","DOIUrl":"https://doi.org/10.1016/j.rmedc.2010.10.003","url":null,"abstract":"<div><p>We present the occurrence of the free distal aspect of a screw which belongs to cervical vertebra implant penetrated the trachea and resulted in tracheal obstruction. This occurrence has not been previously reported in the English literature. This event occurred, four years ago following a cervical vertebra implant surgery for herniated nucleus pulposus. The patient has been suffering from dyspnea after the surgery. Patient had been diagnosed as chronic asthma bronchiale and given asthma medications by different doctors since the operation. The patient presented to our hospital with the same complaints. Her pulmonary function test revealed upper airway obstruction, thereupon we ordered a neck tomography. The tomography showed a foreign body in the trachea of the patient. The implant and the screw were safely removed. The patient’s complaints are recovered after removal. Her pulmonary function test was improved.</p></div>","PeriodicalId":89478,"journal":{"name":"Respiratory medicine CME","volume":"4 3","pages":"Pages 146-148"},"PeriodicalIF":0.0,"publicationDate":"2011-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.rmedc.2010.10.003","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"137087986","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Philippe R. Bauer , Bryan J. Krajicek , Craig E. Daniels , Sejal S. Shah , Jay H. Ryu
{"title":"Silicone breast implant-induced lymphadenopathy: 18 Cases","authors":"Philippe R. Bauer , Bryan J. Krajicek , Craig E. Daniels , Sejal S. Shah , Jay H. Ryu","doi":"10.1016/j.rmedc.2011.01.001","DOIUrl":"https://doi.org/10.1016/j.rmedc.2011.01.001","url":null,"abstract":"<div><h3>Background</h3><p>There is renewed concern regarding the adverse effects of silicone breast implants, particularly regarding implant rupture. Silicone leak can spread to regional lymph nodes, and remote organs, sometimes mimicking malignancy. The aim of this study was to determine the clinical and radiologic features, pathologic findings, and outcome associated with silicone-induced lymphadenopathy in patients with silicone breast implants.</p></div><div><h3>Methods</h3><p>Retrospective review of cases of silicone-induced lymphadenopathy after breast implant encountered at Mayo Clinic Rochester between 1998 and 2008.</p></div><div><h3>Results</h3><p>We identified 18 cases of silicone-induced lymphadenopathy (axillary, supraclavicular, internal mammary, and mediastinal). Fifteen patients had breast reconstruction and 3 breast augmentation. Most patients experienced symptoms. One patient had pulmonary opacities, retroperitoneal lymphadenopathy, hypercalcemia, and confirmed silicone in the thyroid, and the omentum. Imaging included mammography, chest CT, breast MRI and PET scan. Lymph node biopsies and/or breast implant removal confirmed the diagnosis with characteristic granulomatous inflammation and giant cell reaction and/or implant rupture.</p></div><div><h3>Conclusions</h3><p>Silicone-induced lymphadenopathy can be confused for malignancy or recurrent breast cancer in patients with breast implants. Silicone breast implant ruptures are relatively uncommon, but are under-recognized. Silicone usually migrates to the axillary lymph nodes but may migrate to other lymph nodes as well as extranodal sites.</p></div>","PeriodicalId":89478,"journal":{"name":"Respiratory medicine CME","volume":"4 3","pages":"Pages 126-130"},"PeriodicalIF":0.0,"publicationDate":"2011-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.rmedc.2011.01.001","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"137088774","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Bronchoalveolar carcinoma on a background of chronic extrinsic allergic alveolitis in a spice miller – A case report","authors":"Mitrakrishan Chrishan Shivanthan, Bandula Wijesiriwardena","doi":"10.1016/j.rmedc.2011.01.004","DOIUrl":"https://doi.org/10.1016/j.rmedc.2011.01.004","url":null,"abstract":"<div><p>A case of bronchoalveolar carcinoma developing on a background of chronic extrinsic allergic alveolitis is discussed highlighting the likely increased risk of lung malignancies in chronic organic hypersensitivity pneumonitis and the need for further cohort studies and possible impact on occupation related safety and compensation.</p></div>","PeriodicalId":89478,"journal":{"name":"Respiratory medicine CME","volume":"4 3","pages":"Pages 119-120"},"PeriodicalIF":0.0,"publicationDate":"2011-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.rmedc.2011.01.004","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"137088776","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Juan Antonio Mazzei , Analía Barro , Mariano Egidio Mazzei , Tamara Portas , Hugo Esteva
{"title":"Biphasic flow volume curve due to obstruction of main bronchus by bronchogenic cyst","authors":"Juan Antonio Mazzei , Analía Barro , Mariano Egidio Mazzei , Tamara Portas , Hugo Esteva","doi":"10.1016/j.rmedc.2011.01.005","DOIUrl":"https://doi.org/10.1016/j.rmedc.2011.01.005","url":null,"abstract":"<div><p>The biphasic curve or bicompartmental flow volume obtained during the forced maneuver is the characteristic of the obstruction of a main bronchus. We report the case of a 64-year-old woman, with progressive dyspnea, coughing and wheezing localized in the left hemithorax, who had been diagnosed with bronchial asthma and was not responding to treatment. The flow volume curve showed an end inspiratory arm configuration compatible with unilateral obstruction of a main bronchus. Chest computed tomography with three-dimensional reconstruction showed a left main bronchus compression by a cyst formation, the bronchoscopy confirmed the obstruction. At surgery a bronchogenic cyst was resected.</p><p>After the procedure, dyspnea, cough, expectoration and wheezing disappeared. The postoperative flow volume curve showed a normal configuration. We are not aware of a previous report of a biphasic flow volume curve due to a mediastinal bronchogenic cyst.</p><p>The flow volume curve is a noninvasive procedure useful in the diagnosis of unilateral obstruction of a main bronchus.</p></div>","PeriodicalId":89478,"journal":{"name":"Respiratory medicine CME","volume":"4 3","pages":"Pages 116-118"},"PeriodicalIF":0.0,"publicationDate":"2011-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.rmedc.2011.01.005","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"137088778","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Infant pulmonary function testing guides therapy in cystic fibrosis lung disease","authors":"Amy G. Filbrun, Carey N. Lumeng, Samya Z. Nasr","doi":"10.1016/j.rmedc.2010.01.005","DOIUrl":"https://doi.org/10.1016/j.rmedc.2010.01.005","url":null,"abstract":"<div><p>Longitudinal measures of pulmonary function are a fundamental part of care for older children and adults with cystic fibrosis. The dilemma for the clinician caring for infants with cystic fibrosis is how to best objectively assess and treat early lung disease to maintain good lung health for as long as possible. In this report, we present two cases where infant pulmonary function testing revealed an unexpected degree of airway pathology that altered our clinical decision making. Following treatment with intravenous antibiotics, infant pulmonary function tests demonstrated dramatic improvement. These cases demonstrate the utility of infant pulmonary function testing in guiding the management of infants with cystic fibrosis.</p></div>","PeriodicalId":89478,"journal":{"name":"Respiratory medicine CME","volume":"4 1","pages":"Pages 17-19"},"PeriodicalIF":0.0,"publicationDate":"2011-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.rmedc.2010.01.005","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"137091390","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"An unusual cause of pulmonary artery hypertension in a patient with chronic obstructive airway disease","authors":"Ankur Girdhar , Amita Singh , Abubakr A. Bajwa","doi":"10.1016/j.rmedc.2010.04.002","DOIUrl":"https://doi.org/10.1016/j.rmedc.2010.04.002","url":null,"abstract":"<div><p>Pulmonary artery hypertension is a common entity in patients with obstructive airway disease mostly associated with chronic hypoxia. Presence of pulmonary artery hypertension can add to the respiratory distress patients experience during the clinical course of the disease. This is a case of a 55 year old man with severe chronic obstructive pulmonary disease with the alternative diagnosis of anomalous pulmonary venous return as a cause of pulmonary hypertension and persistent dyspnoea. This alternative etiology can lead to unsatisfactory results inspite of optimal treatment and therefore needs to be addressed individually.</p></div>","PeriodicalId":89478,"journal":{"name":"Respiratory medicine CME","volume":"4 1","pages":"Pages 44-46"},"PeriodicalIF":0.0,"publicationDate":"2011-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.rmedc.2010.04.002","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"137091602","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}