Management of isoniazid-resistant pulmonary tuberculosis in patient with non-functioning bowel on the intensive care unit

Abstract

A young Turkish woman presented with abdominal sepsis. Terminal ileal Crohn's disease was diagnosed on histology. She was treated with intravenous steroids and bowel resection but required multiple laparotomies for recurrent peritonitis. Isoniazid-resistant Mycobacterium tuberculosis was cultured from sputum. Treatment of tuberculosis was complicated by a long post-operative period of non-functioning bowel, which necessitated intravenous agents.