Respiratory medicine CME最新文献

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Very long standing fever in an immunocompetent host 在免疫能力强的宿主体内长期发热
Respiratory medicine CME Pub Date : 2011-01-01 DOI: 10.1016/j.rmedc.2010.05.005
Voicu Tudorache , Rodica Potre Oncu , Daniel Trăilă , Cristian Oancea
{"title":"Very long standing fever in an immunocompetent host","authors":"Voicu Tudorache ,&nbsp;Rodica Potre Oncu ,&nbsp;Daniel Trăilă ,&nbsp;Cristian Oancea","doi":"10.1016/j.rmedc.2010.05.005","DOIUrl":"https://doi.org/10.1016/j.rmedc.2010.05.005","url":null,"abstract":"<div><p>We present a case of 7 years history of recurrent febrile syndrome associated with constitutional symptoms. Extensive investigations failed to identify an etiological agent. Actually, the patient presents herself with a chest wall tumor and supraclavicular adenopathy.</p><p>Computerized tomography (CT) disclosed chest wall abscess, adjacent costal lytic lesions, pulmonary fibrosis in the left centrohilar area, mediastinal lymphadenopathy, pericardial effusion, partial portal vein thrombosis, multiple hepatic and splenic hypodense lesions and abdominal lymphadenopathy.</p><p>The anatomo-pathological examination of chest wall abscess and supraclavicular adenopathy revealed epithelioid cell granuloma with caseous necrosis. The evaluation for immunocompromised status has found no significant anomaly.</p><p>Antituberculosis chemotherapy resulted in resolution of fever and clinical improvement.</p><p>Final diagnosis: disseminated tuberculosis (lymph node, chest wall abscess, pericardial, hepatic, splenic and pulmonary?) complicated with partial portal vein thrombosis in an immunocompetent host.</p></div>","PeriodicalId":89478,"journal":{"name":"Respiratory medicine CME","volume":"4 2","pages":"Pages 93-95"},"PeriodicalIF":0.0,"publicationDate":"2011-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.rmedc.2010.05.005","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"137401608","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
131I-labeled lipiodol-induced interstitial pneumonia 131i标记的脂醇诱导的间质性肺炎
Respiratory medicine CME Pub Date : 2011-01-01 DOI: 10.1016/j.rmedc.2010.05.001
S. Jouneau , E. Polard , E. Vauléon , S. Caulet-Maugendre , A.C. Volatron , P. Delaval
{"title":"131I-labeled lipiodol-induced interstitial pneumonia","authors":"S. Jouneau ,&nbsp;E. Polard ,&nbsp;E. Vauléon ,&nbsp;S. Caulet-Maugendre ,&nbsp;A.C. Volatron ,&nbsp;P. Delaval","doi":"10.1016/j.rmedc.2010.05.001","DOIUrl":"https://doi.org/10.1016/j.rmedc.2010.05.001","url":null,"abstract":"<div><p>Drug-induced interstitial pneumonia is a severe disease that has been reportedly caused by more than 100 compounds, the most common being amiodarone, methotrexate and bleomycin. We report a case of fatal acute interstitial pneumonia occurring after a second injection of <sup>131</sup>I-labeled lipiodol for hepatocellular carcinoma treatment. Infectious pneumonia was ruled out and lung biopsy revealed a pattern of usual interstitial pneumonia. Despite early initiation of systemic corticosteroids and additionally, antioxidant medications, the patient’s condition gradually worsened and he died 24 days after admission. <sup>131</sup>I-labeled lipiodol-induced interstitial pneumonia is probably frequently undiagnosed. A better knowledge of this disease would help to estimate its true incidence and may impact on the perceived risk/benefit ratio for its treatment. Moreover, this may have consequences on the prescription of <sup>131</sup>I-labeled lipiodol.</p></div>","PeriodicalId":89478,"journal":{"name":"Respiratory medicine CME","volume":"4 1","pages":"Pages 41-43"},"PeriodicalIF":0.0,"publicationDate":"2011-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.rmedc.2010.05.001","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"137091601","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
The pulmonary radiologic findings of rheumatoid arthritis 类风湿关节炎的肺部放射学表现
Respiratory medicine CME Pub Date : 2011-01-01 DOI: 10.1016/j.rmedc.2011.03.003
Sevket Ozkaya , Salih Bilgin , Semra Hamsici , Serhat Findik
{"title":"The pulmonary radiologic findings of rheumatoid arthritis","authors":"Sevket Ozkaya ,&nbsp;Salih Bilgin ,&nbsp;Semra Hamsici ,&nbsp;Serhat Findik","doi":"10.1016/j.rmedc.2011.03.003","DOIUrl":"https://doi.org/10.1016/j.rmedc.2011.03.003","url":null,"abstract":"<div><p>The rheumatoid arthritis (RA) is can affect multiple organs and tissues including the lung. Several pleuropulmonary manifestations are associated with rheumatoid arthritis involving the lung parenchyma, pleura, airways, and vasculature. The various pulmonary radiological findings have been defined in patients with RA.</p><p>In this study, we aimed to retrospectively evaluate of the pulmonary radiologic findings in the five patients with RA.</p><p>In the present study, pleural effusion, hydropneumothorax, chylothorax, pulmonary micronodular, macronodular and necrobiotic nodular lesions, pleural plagues, ground glass opacity and interstitial lung diseases were defined according to chest radiographs and computed tomography. The most common pulmonary radiologic findings were pulmonary nodules in three of patients, necrobiotic nodule in two of patients, pleural plague in two of patients and pleural effusion in two patients. The one of them had hydropneumothorax. Interstitial lung diseases were defined in two of patients.</p><p>In conclusion, the pulmonary changes may be accompanied as a systemic component of the RA. If these changes are well recognized, they can help in the diagnosis of the RA.</p></div>","PeriodicalId":89478,"journal":{"name":"Respiratory medicine CME","volume":"4 4","pages":"Pages 187-192"},"PeriodicalIF":0.0,"publicationDate":"2011-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.rmedc.2011.03.003","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"137225889","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 6
Lambda light chain multiple myeloma presenting as pleural mass Lambda轻链多发性骨髓瘤表现为胸膜肿块
Respiratory medicine CME Pub Date : 2011-01-01 DOI: 10.1016/j.rmedc.2010.01.007
Mohammad Shameem, Jamal Akhtar, Rakesh Bhargava, Zuber Ahmad, Ummul Baneen, Nafees Ahmad Khan
{"title":"Lambda light chain multiple myeloma presenting as pleural mass","authors":"Mohammad Shameem,&nbsp;Jamal Akhtar,&nbsp;Rakesh Bhargava,&nbsp;Zuber Ahmad,&nbsp;Ummul Baneen,&nbsp;Nafees Ahmad Khan","doi":"10.1016/j.rmedc.2010.01.007","DOIUrl":"https://doi.org/10.1016/j.rmedc.2010.01.007","url":null,"abstract":"<div><p>Light chain multiple myeloma occurs in 20% of multiple myeloma cases. Extramedullary dissemination of multiple myeloma is rare and involvement of pleura by it is even more rare. A 40 years old female patient presented with complains of recurrent vomiting for last 2 months and cough with expectoration for last 1 week. Chest X-Ray (PA view) showed a rounded homogenous opacity in mid zone of left lung field. CECT (thorax) showed pleura based soft tissue density mass lesions overlying apicoposterior segment of left upper lobe and lingular lobe with lytic destruction of underlying 2nd rib. Ultrasound scan of abdomen was normal. CT guided FNAC from soft tissue mass lesion of left side revealed atypical plasma cells, some of them were binucleate and few appear pleomorphic. Bone marrow aspiration showed 20% atypical plasma cells. Serum protein electrophoresis revealed a thin discrete band in gamma globulin region, while serum immunofixation electrophoresis showed presence of lambda light chain band only, with absence of kappa band, IgG band, IgM band and IgA band. Patient was diagnosed as a case of lambda light chain multiple myeloma with extramedullary dissemination to pleura presenting as pleural mass.</p></div>","PeriodicalId":89478,"journal":{"name":"Respiratory medicine CME","volume":"4 1","pages":"Pages 12-14"},"PeriodicalIF":0.0,"publicationDate":"2011-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.rmedc.2010.01.007","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"92013240","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
Idiopathic constrictive bronchiolitis with rapidly progressive bronchiectasis and Mycobacterium kansasii infection 特发性缩窄性细支气管炎伴快速进行性支气管扩张和堪萨斯分枝杆菌感染
Respiratory medicine CME Pub Date : 2011-01-01 DOI: 10.1016/j.rmedc.2011.03.007
Sandeep Raparla , Eric P. Schmidt , David B. Pearse
{"title":"Idiopathic constrictive bronchiolitis with rapidly progressive bronchiectasis and Mycobacterium kansasii infection","authors":"Sandeep Raparla ,&nbsp;Eric P. Schmidt ,&nbsp;David B. Pearse","doi":"10.1016/j.rmedc.2011.03.007","DOIUrl":"https://doi.org/10.1016/j.rmedc.2011.03.007","url":null,"abstract":"<div><p>Constrictive bronchiolitis results in airways obstruction with progressive lung hyperinflation causing dyspnea and eventual respiratory failure. There are many known causes including rheumatic diseases, infections and toxic inhalations. We describe a 58-year-old man with no preexisting lung disease who suffered rapid loss of lung function with hyperinflation over months in association with rapidly progressive radiographic bronchiectasis. Airway cultures grew <em>Mycobacterium kansasii</em>, <em>Pseudomonas aeruginosa</em> and <em>Aspergillus fumigatus</em>; lung biopsy showed constrictive bronchiolitis that was clinically idiopathic. His respiratory symptoms and pulmonary function rapidly improved within a week of high-dose corticosteroid therapy. We suggest that a diagnosis of constrictive bronchiolitis should be considered in patients with a combination of new rapidly progressive lung hyperinflation and worsening bronchiectasis. We hypothesize that the bronchiolitis-associated bronchiectasis may occur from a predisposition for secondary infections known to cause large airway wall damage. Identification and adequate treatment of these infections is critical if concurrent high-dose corticosteroid therapy is attempted to alleviate the constrictive bronchiolitis.</p></div>","PeriodicalId":89478,"journal":{"name":"Respiratory medicine CME","volume":"4 4","pages":"Pages 172-174"},"PeriodicalIF":0.0,"publicationDate":"2011-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.rmedc.2011.03.007","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"137225861","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
A large tracheal capillary hemangioma treated with interventional bronchoscopy 介入支气管镜治疗大气管毛细血管瘤
Respiratory medicine CME Pub Date : 2011-01-01 DOI: 10.1016/j.rmedc.2010.10.002
Enguo Chen, Xianyan Yu, Ruifeng Zhang, Peipei Wang, Kejing Ying
{"title":"A large tracheal capillary hemangioma treated with interventional bronchoscopy","authors":"Enguo Chen,&nbsp;Xianyan Yu,&nbsp;Ruifeng Zhang,&nbsp;Peipei Wang,&nbsp;Kejing Ying","doi":"10.1016/j.rmedc.2010.10.002","DOIUrl":"https://doi.org/10.1016/j.rmedc.2010.10.002","url":null,"abstract":"<div><p>The most frequent causes of hemoptysis are infectious diseases, malignant tumors, cardiovascular disorders, and inflammatory diseases. Lobular capillary hemangioma (LCH) has rarely been reported as a cause of hemoptysis. This vascular lesion usually presents on the skin or mucous membranes, and lesion predominantly affects children with a mean age of approximately six years. It typically presents as a solitary glistening red vascular papule or nodule, prone to ulceration and bleeding. The following case illustrates the occurrence of an LCH of the tracheal mucosa treated with interventional bronchoscopy.</p></div>","PeriodicalId":89478,"journal":{"name":"Respiratory medicine CME","volume":"4 2","pages":"Pages 60-61"},"PeriodicalIF":0.0,"publicationDate":"2011-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.rmedc.2010.10.002","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"137401424","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 12
Two cases of stem cell therapy for pulmonary hypertension: A clinical report 干细胞治疗肺动脉高压2例临床报告
Respiratory medicine CME Pub Date : 2011-01-01 DOI: 10.1016/j.rmedc.2010.09.002
Neal M. Patel, Charles D. Burger
{"title":"Two cases of stem cell therapy for pulmonary hypertension: A clinical report","authors":"Neal M. Patel,&nbsp;Charles D. Burger","doi":"10.1016/j.rmedc.2010.09.002","DOIUrl":"https://doi.org/10.1016/j.rmedc.2010.09.002","url":null,"abstract":"<div><p>In this report we discuss two cases of patients with Pulmonary Arterial Hypertension. Both patients were evaluated and were recommended therapy according to current acceptable guidelines. Despite these recommendations, each patient sought on their own accord, additional therapy in the form of stem cell therapy. They subsequently received an infusion of stem cells into their pulmonary circulation. Objective and subjective measures were followed prior to and following infusion. After a review of each case we briefly discuss the decisions a physician must face when a patient seeks therapies not proven safe or effective by a governing authority.</p></div>","PeriodicalId":89478,"journal":{"name":"Respiratory medicine CME","volume":"4 2","pages":"Pages 70-74"},"PeriodicalIF":0.0,"publicationDate":"2011-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.rmedc.2010.09.002","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"137401429","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Intrapleural administration of Pulmozyme for pleural empyema 胸腔内给药肺酶治疗胸膜脓肿
Respiratory medicine CME Pub Date : 2011-01-01 DOI: 10.1016/j.rmedc.2010.12.002
Vladimir Bobek , Grzegorz Kacprzak , Andrzej Majewski , Jerzy Kolodziej
{"title":"Intrapleural administration of Pulmozyme for pleural empyema","authors":"Vladimir Bobek ,&nbsp;Grzegorz Kacprzak ,&nbsp;Andrzej Majewski ,&nbsp;Jerzy Kolodziej","doi":"10.1016/j.rmedc.2010.12.002","DOIUrl":"https://doi.org/10.1016/j.rmedc.2010.12.002","url":null,"abstract":"<div><p>Empyema is a severe complication of different diseases and traumas. Management of this complication is difficult and should comprise general and local procedures. The general procedure is mainly based on administering wide-spectrum antibiotics. Local management depends on general condition, but in all cases the essential procedure is inserting a drain into the pleural cavity and evacuation the pus. Sometimes pus is very thick and its evacuation and re-expansion of the lung is rather impossible. In these patients surgical procedures are required. The use of intrapleural enzymes to aid drainage was first described in 1949 by Tillett and Sherry using a mixture of streptokinase and streptococcal DNase (deoxyribonuclease).<span><sup>1</sup></span> In recent years purified streptokinase has come into widespread use, but recent studies suggest that it has no effect on pus viscosity. DNase reduces pus viscosity and may be more useful in treatment.<span><sup>2</sup></span> We report a case of intrapleural administration of Pulmozyme (alfa dornase – deoxyribonuclease (HOFFMANN-LA ROCHE AG) in dosage 2×2,5 mg with a good effect caused by changes in pus viscosity.</p></div>","PeriodicalId":89478,"journal":{"name":"Respiratory medicine CME","volume":"4 3","pages":"Pages 114-115"},"PeriodicalIF":0.0,"publicationDate":"2011-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.rmedc.2010.12.002","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"137088777","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Invasive pulmonary aspergillosis in an immunocompetent patient 免疫功能正常患者的侵袭性肺曲菌病
Respiratory medicine CME Pub Date : 2011-01-01 DOI: 10.1016/j.rmedc.2010.12.004
Vikas Pathak , Iliana Samara Hurtado Rendon , Ronald L. Ciubotaru
{"title":"Invasive pulmonary aspergillosis in an immunocompetent patient","authors":"Vikas Pathak ,&nbsp;Iliana Samara Hurtado Rendon ,&nbsp;Ronald L. Ciubotaru","doi":"10.1016/j.rmedc.2010.12.004","DOIUrl":"https://doi.org/10.1016/j.rmedc.2010.12.004","url":null,"abstract":"<div><p>Aspergillosis is the group of diseases caused by the <em>Aspergillus</em> species, which cause a broad spectrum of disease, ranging from hypersensitivity reactions to direct angioinvasion. The major forms of pulmonary aspergillosis range from aspergilloma with a relatively benign course to invasive pulmonary aspergillosis, which is uniformly fatal. Invasive pulmonary aspergillosis more commonly occurs in immunocompromised patients, with a rapidly progressing course leading to death. We report a case of an immunocompetent patient who developed fatal pneumonia secondary to <em>Aspergillus fumigatus</em>.</p></div>","PeriodicalId":89478,"journal":{"name":"Respiratory medicine CME","volume":"4 3","pages":"Pages 105-106"},"PeriodicalIF":0.0,"publicationDate":"2011-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.rmedc.2010.12.004","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"137088780","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
Synchronous primary pulmonary adenocarcinoma and MALToma in a patient with Sjögren's syndrome: Case report Sjögren综合征患者并发原发性肺腺癌和MALToma 1例报告
Respiratory medicine CME Pub Date : 2011-01-01 DOI: 10.1016/j.rmedc.2010.01.002
Mitsuhiro Kamiyoshihara , Toshiteru Nagashima , Takashi Ibe , Atsushi Takise , Hideaki Itou
{"title":"Synchronous primary pulmonary adenocarcinoma and MALToma in a patient with Sjögren's syndrome: Case report","authors":"Mitsuhiro Kamiyoshihara ,&nbsp;Toshiteru Nagashima ,&nbsp;Takashi Ibe ,&nbsp;Atsushi Takise ,&nbsp;Hideaki Itou","doi":"10.1016/j.rmedc.2010.01.002","DOIUrl":"https://doi.org/10.1016/j.rmedc.2010.01.002","url":null,"abstract":"<div><p>The present report describes a very rare case of synchronous primary pulmonary adenocarcinoma and MALToma in a patient with Sjögren's syndrome. A 73-year-old woman with a history of Sjögren's syndrome was referred because of an abnormal shadow on X-ray. Chest radiograph revealed an irregularly shaped mass in the right lower lobe of the lung. Computed tomography showed a parenchymal lesion with an air bronchogram and spiculated contours. Chronic inflammation was seen on transbronchial lung biopsy, but clinically a pulmonary malignant tumor was suspected. No obvious abnormality other than that of the lung was detected. The patient underwent a right lower lobectomy with mediastinal lymph node dissection. The histological features of the surgical specimen were consistent with bronchiolo-alveolar carcinoma and, separately, MALT lymphoma.</p></div>","PeriodicalId":89478,"journal":{"name":"Respiratory medicine CME","volume":"4 1","pages":"Pages 27-29"},"PeriodicalIF":0.0,"publicationDate":"2011-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.rmedc.2010.01.002","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"137091366","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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