Anti-infective agents in medicinal chemistry最新文献

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Anti-inflammatory Property of AMP-activated Protein Kinase. AMP活化蛋白激酶的抗炎特性
Anti-infective agents in medicinal chemistry Pub Date : 2020-01-01 DOI: 10.2174/1871523018666190830100022
Humaira B Noor, Nusrat A Mou, Liyad Salem, Md F A Shimul, Soumick Biswas, Rowshon Akther, Salma Khan, Sabbir Raihan, Md M Mohib, Md A T Sagor
{"title":"Anti-inflammatory Property of AMP-activated Protein Kinase.","authors":"Humaira B Noor, Nusrat A Mou, Liyad Salem, Md F A Shimul, Soumick Biswas, Rowshon Akther, Salma Khan, Sabbir Raihan, Md M Mohib, Md A T Sagor","doi":"10.2174/1871523018666190830100022","DOIUrl":"10.2174/1871523018666190830100022","url":null,"abstract":"<p><strong>Background: </strong>One of the many debated topics in inflammation research is whether this scenario is really an accelerated form of human wound healing and immunityboosting or a push towards autoimmune diseases. The answer requires a better understanding of the normal inflammatory process, including the molecular pathology underlying the possible outcomes. Exciting recent investigations regarding severe human inflammatory disorders and autoimmune conditions have implicated molecular changes that are also linked to normal immunity, such as triggering factors, switching on and off, the influence of other diseases and faulty stem cell homeostasis, in disease progression and development.</p><p><strong>Methods: </strong>We gathered around and collected recent online researches on immunity, inflammation, inflammatory disorders and AMPK. We basically searched PubMed, Scopus and Google Scholar to assemble the studies which were published since 2010.</p><p><strong>Results: </strong>Our findings suggested that inflammation and related disorders are on the verge and interfere in the treatment of other diseases. AMPK serves as a key component that prevents various kinds of inflammatory signaling. In addition, our table and hypothetical figures may open a new door in inflammation research, which could be a greater therapeutic target for controlling diabetes, obesity, insulin resistance and preventing autoimmune diseases.</p><p><strong>Conclusion: </strong>The relationship between immunity and inflammation becomes easily apparent. Yet, the essence of inflammation turns out to be so startling that the theory may not be instantly established and many possible arguments are raised for its clearance. However, this study might be able to reveal some possible approaches where AMPK can reduce or prevent inflammatory disorders.</p>","PeriodicalId":89320,"journal":{"name":"Anti-infective agents in medicinal chemistry","volume":"19 1","pages":"2-41"},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7460777/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48041378","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Structure-based Discovery of Novel Antibacterials 基于结构的新型抗菌药物的发现
Anti-infective agents in medicinal chemistry Pub Date : 2010-09-30 DOI: 10.2174/187152110794785068
Huan-qiu Li, Pengcheng Lv, Lei Shi, Hailiang Zhu
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引用次数: 0
Emerging Antimicrobial Applications of Nitric Oxide (NO) and NO-Releasing Materials 一氧化氮(NO)及其释放材料的新型抗菌应用
Anti-infective agents in medicinal chemistry Pub Date : 2010-09-30 DOI: 10.2174/187152110794785086
Genevieve M. Halpenny and Pradip K. Mascharak
{"title":"Emerging Antimicrobial Applications of Nitric Oxide (NO) and NO-Releasing Materials","authors":"Genevieve M. Halpenny and Pradip K. Mascharak","doi":"10.2174/187152110794785086","DOIUrl":"https://doi.org/10.2174/187152110794785086","url":null,"abstract":"","PeriodicalId":89320,"journal":{"name":"Anti-infective agents in medicinal chemistry","volume":"9 1","pages":"187-197"},"PeriodicalIF":0.0,"publicationDate":"2010-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68024490","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 38
Synthesis of Some New Monocyclic β-Lactams Bearing a Morpholine Moiety at their N1 Positions as Antifungal Agents 新型N1位含Morpholine的单环β-内酰胺类抗真菌药物的合成
Anti-infective agents in medicinal chemistry Pub Date : 2010-09-30 DOI: 10.2174/187152110794785040
A. Jarrahpour, M. Eskandari, K. Zomorodian, E. Barati, Raheleh Ashori, M. Vaziri, K. Pakshir
{"title":"Synthesis of Some New Monocyclic β-Lactams Bearing a Morpholine Moiety at their N1 Positions as Antifungal Agents","authors":"A. Jarrahpour, M. Eskandari, K. Zomorodian, E. Barati, Raheleh Ashori, M. Vaziri, K. Pakshir","doi":"10.2174/187152110794785040","DOIUrl":"https://doi.org/10.2174/187152110794785040","url":null,"abstract":"","PeriodicalId":89320,"journal":{"name":"Anti-infective agents in medicinal chemistry","volume":"9 1","pages":"205-219"},"PeriodicalIF":0.0,"publicationDate":"2010-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68023599","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 4
Novel, Unifying Phagomimetic Mechanism of Vancomycin Therapeutic Action and Toxicity: Polyphenol, Electron Transfer and Reactive Oxygen Species 万古霉素治疗作用和毒性的新颖、统一的拟吞噬机制:多酚、电子转移和活性氧
Anti-infective agents in medicinal chemistry Pub Date : 2010-09-30 DOI: 10.2174/187152110794785059
P. Kovacic, R. Somanathan
{"title":"Novel, Unifying Phagomimetic Mechanism of Vancomycin Therapeutic Action and Toxicity: Polyphenol, Electron Transfer and Reactive Oxygen Species","authors":"P. Kovacic, R. Somanathan","doi":"10.2174/187152110794785059","DOIUrl":"https://doi.org/10.2174/187152110794785059","url":null,"abstract":"","PeriodicalId":89320,"journal":{"name":"Anti-infective agents in medicinal chemistry","volume":"9 1","pages":"180-186"},"PeriodicalIF":0.0,"publicationDate":"2010-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68023121","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Investigation of 2-Fluoro Benzoic Acid Derivatives as Influenza A Viral Sialidase Selective Inhibitors 2-氟苯甲酸衍生物作为甲型流感病毒唾液酸酶选择性抑制剂的研究
Anti-infective agents in medicinal chemistry Pub Date : 2010-09-30 DOI: 10.2174/187152110794785077
S. Magesh, N. Sriwilaijaroen, V. Savita, H. Ando, T. Miyagi, Yasuo Suzuki, H. Ishida, M. Kiso
{"title":"Investigation of 2-Fluoro Benzoic Acid Derivatives as Influenza A Viral Sialidase Selective Inhibitors","authors":"S. Magesh, N. Sriwilaijaroen, V. Savita, H. Ando, T. Miyagi, Yasuo Suzuki, H. Ishida, M. Kiso","doi":"10.2174/187152110794785077","DOIUrl":"https://doi.org/10.2174/187152110794785077","url":null,"abstract":"","PeriodicalId":89320,"journal":{"name":"Anti-infective agents in medicinal chemistry","volume":"9 1","pages":"198-204"},"PeriodicalIF":0.0,"publicationDate":"2010-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68023182","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Membrane Drug Transport in Helminths 蠕虫的膜药物转运
Anti-infective agents in medicinal chemistry Pub Date : 2010-06-30 DOI: 10.2174/1871521411009030113
D. Kerboeuf, M. Riou, C. Neveu, Mohamed Issouf
{"title":"Membrane Drug Transport in Helminths","authors":"D. Kerboeuf, M. Riou, C. Neveu, Mohamed Issouf","doi":"10.2174/1871521411009030113","DOIUrl":"https://doi.org/10.2174/1871521411009030113","url":null,"abstract":"","PeriodicalId":89320,"journal":{"name":"Anti-infective agents in medicinal chemistry","volume":"9 1","pages":"113-129"},"PeriodicalIF":0.0,"publicationDate":"2010-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68024564","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 16
Anthelmintic therapy in ruminant species: Understanding of the host-drug-parasite interaction 反刍动物的驱虫药治疗:了解宿主-药物-寄生虫相互作用
Anti-infective agents in medicinal chemistry Pub Date : 2010-06-30 DOI: 10.2174/1871521411009030130
C. Lanusse
{"title":"Anthelmintic therapy in ruminant species: Understanding of the host-drug-parasite interaction","authors":"C. Lanusse","doi":"10.2174/1871521411009030130","DOIUrl":"https://doi.org/10.2174/1871521411009030130","url":null,"abstract":"Fil: Lanusse, Carlos Edmundo. Universidad Nacional del Centro de la Provincia de Buenos Aires. Facultad de Ciencias Veterinarias. Departamento de Fisiopatologia. Laboratorio de Farmacologia; Argentina. Consejo Nacional de Investigaciones Cientificas y Tecnicas; Argentina","PeriodicalId":89320,"journal":{"name":"Anti-infective agents in medicinal chemistry","volume":"9 1","pages":"130-138"},"PeriodicalIF":0.0,"publicationDate":"2010-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68024578","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
Mutations Associated with Anthelmintic Drug Resistance 与驱虫虫耐药性相关的突变
Anti-infective agents in medicinal chemistry Pub Date : 2010-06-30 DOI: 10.2174/1871521411009030105
R. A. Silvestre
{"title":"Mutations Associated with Anthelmintic Drug Resistance","authors":"R. A. Silvestre","doi":"10.2174/1871521411009030105","DOIUrl":"https://doi.org/10.2174/1871521411009030105","url":null,"abstract":"","PeriodicalId":89320,"journal":{"name":"Anti-infective agents in medicinal chemistry","volume":"9 1","pages":"105-112"},"PeriodicalIF":0.0,"publicationDate":"2010-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68024553","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 13
Mathematical Models for the Management of Helminth Parasites: From Biological Processes to the Evolution of Anthelmintic Resistance 寄生虫管理的数学模型:从生物过程到抗虫进化
Anti-infective agents in medicinal chemistry Pub Date : 2010-06-30 DOI: 10.2174/1871521411009030139
Sabrina Gaba and Anne Silvestre
{"title":"Mathematical Models for the Management of Helminth Parasites: From Biological Processes to the Evolution of Anthelmintic Resistance","authors":"Sabrina Gaba and Anne Silvestre","doi":"10.2174/1871521411009030139","DOIUrl":"https://doi.org/10.2174/1871521411009030139","url":null,"abstract":"","PeriodicalId":89320,"journal":{"name":"Anti-infective agents in medicinal chemistry","volume":"9 1","pages":"139-147"},"PeriodicalIF":0.0,"publicationDate":"2010-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68024596","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
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