{"title":"Stigma of Mental Illness-2: Non-compliance and Intervention.","authors":"Amresh Shrivastava, Megan Johnston, Yves Bureau","doi":"10.4103/0973-1229.90276","DOIUrl":"https://doi.org/10.4103/0973-1229.90276","url":null,"abstract":"<p><p>The consequences of stigma are preventable. We argue that individual attention should be provided to patients when dealing with stigma. Also, in order to deal with the impact of stigma on an individual basis, it needs to be assessed during routine clinical examinations, quantified and followed up to observe whether or not treatment can reduce its impact. A patient-centric anti-stigma programme that delivers the above is urgently needed. To this end, this review explores the experiences, treatment barriers and consequences due to stigma. We also offer putative solutions to this problem.</p>","PeriodicalId":89196,"journal":{"name":"Mens sana monographs","volume":"10 1","pages":"85-97"},"PeriodicalIF":0.0,"publicationDate":"2012-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.4103/0973-1229.90276","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"30659787","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Democracy, Human Rights and Women's Health.","authors":"Jalil Safaei","doi":"10.4103/0973-1229.91303","DOIUrl":"https://doi.org/10.4103/0973-1229.91303","url":null,"abstract":"<p><p>Significant improvements in human rights and democracy have been made since the adoption of the Universal Declaration of Human Rights by the United Nations in 1948. Yet, human rights, especially women's rights, are still being violated in many parts of the developing world. The adverse effects of such violations on women's and children's health are well known, but they are rarely measured. This study uses cross-national data from over 145 countries to estimate the impact of democracy and respect for human rights on various measures of women's health while controlling for confounding socio-economic factors such as income, education, fertility and healthcare. It finds that democracy and regards for human rights contribute positively to women's health outcomes, as do socio-economic variables.</p>","PeriodicalId":89196,"journal":{"name":"Mens sana monographs","volume":"10 1","pages":"134-42"},"PeriodicalIF":0.0,"publicationDate":"2012-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.4103/0973-1229.91303","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"30659791","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Of money and trust in medical care redux.","authors":"Joel Lexchin","doi":"10.4103/0973-1229.91294","DOIUrl":"https://doi.org/10.4103/0973-1229.91294","url":null,"abstract":"<p><p>Should we be concerned about financial conflicts of interest (COI) between doctors and the pharmaceutical industry? Some people will say no as there are clearly doctors who celebrate the relationship. Others say that it does not matter to patients, but the evidence says otherwise. Financial COI is different from other types of conflicts because it is voluntary and can be refused. Finally, it is not just the large gifts that are a problem, the small ones also create a \"gift relationship.\" Drug companies know about this and spend billions on promotion with good effect from their point of view. Companies also woo doctors who honestly hold pro-industry points of view to speak on behalf of the companies. There are still multiple examples of financial COI, and although there are isolated examples of improvement, this is still an area of deep concern.</p>","PeriodicalId":89196,"journal":{"name":"Mens sana monographs","volume":"10 1","pages":"143-9"},"PeriodicalIF":0.0,"publicationDate":"2012-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.4103/0973-1229.91294","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"30658632","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Happy new year!","authors":"Ajai R Singh","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":89196,"journal":{"name":"Mens sana monographs","volume":"10 1","pages":"197"},"PeriodicalIF":0.0,"publicationDate":"2012-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/d4/e6/MSM-10-197.PMC3353602.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"30659091","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Mind and consciousness as per j. Krishnamurti.","authors":"Avinash De Sousa","doi":"10.4103/0973-1229.86145","DOIUrl":"https://doi.org/10.4103/0973-1229.86145","url":null,"abstract":"<p><p>The present article looks at mind and consciousness from the perspective of the eminent Indian philosopher, Jiddu Krishnamurti. He believed in total awareness as being essential for a free mind. Human beings always learned from their past, and it was important that they looked inwards and freed themselves from self-perpetuated torment. It was also necessary that they avoided repression. The society in which we live should be organic, where, although individuals had no choice but to dwell in that society, it was one where the interests of the individual and society were the same. He also maintained that religion was always the result of past conditioning. A mind should be investigative and scientific. One could not get pleasure without difficulty, for which living in totality, not in segments, was a must. We often dwell on one part of the consciousness and miss its holistic aspect. One must uncover the mind layer by layer to achieve complete growth. Deeper delving into it and a study of J. Krishnamurti's philosophy is a must for the understanding of human consciousness, in a manner that is simple, yet abstract and deep. </p>","PeriodicalId":89196,"journal":{"name":"Mens sana monographs","volume":"10 1","pages":"198-207"},"PeriodicalIF":0.0,"publicationDate":"2012-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/be/e3/MSM-10-198.PMC3673342.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"31574928","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Treatment-resistant Schizophrenia: Evidence-based Strategies.","authors":"Susanne Englisch, Mathias Zink","doi":"10.4103/0973-1229.91588","DOIUrl":"10.4103/0973-1229.91588","url":null,"abstract":"<p><p>Treatment-resistant symptoms complicate the clinical course of schizophrenia, and a large proportion of patients do not reach functional recovery. In consequence, polypharmacy is frequently used in treatment-refractory cases, addressing psychotic positive, negative and cognitive symptoms, treatment-emergent side effects caused by antipsychotics and comorbid depressive or obsessive-compulsive symptoms. To a large extent, such strategies are not covered by pharmacological guidelines which strongly suggest antipsychotic monotherapy. Add-on strategies comprise combinations of several antipsychotic agents and augmentations with mood stabilizers; moreover, antidepressants and experimental substances are applied. Based on the accumulated evidence of clinical trials and meta-analyses, combinations of clozapine with certain second-generation antipsychotic agents and the augmentation of antipsychotics with antidepressants seem recommendable, while the augmentation with mood stabilizers cannot be considered superior to placebo. Forthcoming investigations will have to focus on innovative pharmacological agents, the clinical spectrum of cognitive deficits and the implementation of cognitive behavioral therapy.</p>","PeriodicalId":89196,"journal":{"name":"Mens sana monographs","volume":"10 1","pages":"20-32"},"PeriodicalIF":0.0,"publicationDate":"2012-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.4103/0973-1229.91588","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"30659783","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Phlegmatic.","authors":"Ajai R Singh","doi":"10.4103/0973-1229.95427","DOIUrl":"https://doi.org/10.4103/0973-1229.95427","url":null,"abstract":"","PeriodicalId":89196,"journal":{"name":"Mens sana monographs","volume":"10 1","pages":"194"},"PeriodicalIF":0.0,"publicationDate":"2012-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.4103/0973-1229.95427","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"30659090","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Drug therapy of attention deficit hyperactivity disorder: current trends.","authors":"Avinash De Sousa, Gurvinder Kalra","doi":"10.4103/0973-1229.87261","DOIUrl":"https://doi.org/10.4103/0973-1229.87261","url":null,"abstract":"<p><p>Attention deficit hyperactivity disorder is a developmental disorder with an age onset prior to 7 years. Children with ADHD have significantly lower ability to focus and sustain attention and also score higher on impulsivity and hyperactivity. Stimulants, such as methylphenidate, have remained the mainstay of ADHD treatment for decades with evidence supporting their use. However, recent years have seen emergence of newer drugs and drug delivery systems, like osmotic release oral systems and transdermal patches, to mention a few. The use of nonstimulant drugs like atomoxetine and various other drugs, such as α-agonists, and a few antidepressants, being used in an off-label manner, have added to the pharmacotherapy of ADHD. This review discusses current trends in drug therapy of ADHD and highlights the promise pharmacogenomics may hold in the future.</p>","PeriodicalId":89196,"journal":{"name":"Mens sana monographs","volume":"10 1","pages":"45-69"},"PeriodicalIF":0.0,"publicationDate":"2012-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.4103/0973-1229.87261","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"30659785","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The Foetal 'Mind' as a Reflection of its Inner Self: Evidence from Colour Doppler Ultrasound of Foetal MCA.","authors":"Sushil Ghanshyam Kachewar, Siddappa Gurubalappa Gandage","doi":"10.4103/0973-1229.85495","DOIUrl":"10.4103/0973-1229.85495","url":null,"abstract":"<p><p>The unborn healthy foetus is looked upon as a blessing by one and all. A plethora of thoughts arise in the brains of expectant parents. But what goes on in the brain of the yet unborn still remains a mystery. 'Foetal mind' is a reflection of functions of its organs of sense, an instrument of knowledge that may even be reduced to machine to demonstrate the effect of sense organs and brain contact. Testimony to this fact are the various waveform patterns obtained non-invasively from the foetal Middle Cerebral Artery (MCA) by using Colour Doppler Ultrasound. Our study, conducted for evaluating the foetal MCA in a rural obstetric population in Maharashtra, India, explains how the MCA - a major artery supplying foetal brain, can give abundant information about foetal heart and foetal stress. When only the foetal heart is stressed by the presence of arrhythmias or ectopic beats, these changes are manifest in the foetal MCA velocity waveform pattern as seen on Colour Doppler study. When the entire foetus is under stress, as in cases of intra uterine growth retardation (IUGR), changes again manifest in the foetal MCA velocity waveform pattern and are designated as the foetal Brain Sparing Effect. Thus scientific evaluation of foetal MCA waveform can objectively demonstrate that the overtly non-communicating foetal brain indeed remains an internal organ of sense and a vital instrument of knowledge to clarify the various effects of sense organs and brain contact. Although the brain parenchyma or cerebral metabolism has not been studied here, cerebral vessels serve as a window to cerebral metabolism, as auto regulatory function of brain leads to changes in haemodynamics of cerebral vessels. Also, like other vessels, MCA mirrors foetal distress and IUGR; but unlike other vessels, e.g. the umbilical or uterine artery, which show these changes in the form of reduction or even reversal of diastolic flow, MCA shows an increase in diastolic component due to brain sparing effect. The unique connection between physical changes in the foetal heart, brain and mental operations are thus critically clarified to some extent, and this helps untangle and comprehend the lattice of mental operations. Although this preliminary study has its limitations, it still carries forward the present corpus of knowledge on the strength of its evidential and critical enquiry and helps unravel the concept of foetal consciousness.</p>","PeriodicalId":89196,"journal":{"name":"Mens sana monographs","volume":"10 1","pages":"98-108"},"PeriodicalIF":0.0,"publicationDate":"2012-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/67/d1/MSM-10-98.PMC3353609.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"30659788","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}