Mens sana monographs最新文献_第10页

The future of schizophrenia pharmacotherapeutics: not so bleak. 精神分裂症药物治疗的未来:没有那么黯淡。

Mens sana monographs Pub Date : 2012-01-01 DOI: 10.4103/0973-1229.91298

William T Carpenter

引用次数: 3

Science of the mind. 心灵科学。

Mens sana monographs Pub Date : 2012-01-01 DOI: 10.4103/0973-1229.86137

C Shamasundar

引用次数: 1

Medicalization: current concept and future directions in a bionic society. 医疗化：仿生社会的当前概念和未来方向。

Mens sana monographs Pub Date : 2012-01-01 DOI: 10.4103/0973-1229.91587

Antonio Maturo

引用次数: 0

Criminals in the Citadel and Deceit all along the Watchtower: Irresponsibility, Fraud, and Complicity in the Search for Scientific Truth. 城堡里的罪犯和瞭望塔上的欺骗:寻找科学真理中的不负责任、欺诈和共谋。

Mens sana monographs Pub Date : 2012-01-01 DOI: 10.4103/0973-1229.91426

Prathap Tharyan

{"title":"Criminals in the Citadel and Deceit all along the Watchtower: Irresponsibility, Fraud, and Complicity in the Search for Scientific Truth.","authors":"Prathap Tharyan","doi":"10.4103/0973-1229.91426","DOIUrl":"https://doi.org/10.4103/0973-1229.91426","url":null,"abstract":"Scientific research aims to use reliable methods to produce generalizable new knowledge in order to understand the human condition and maximize human potential. The sanctity accorded to scientific research has been violated by numerous instances of research fraud, as well as deceptive and conflicted research that have seriously harmed people, subverted the evidence-base, wasted valuable resources, and undermined public trust. This deception by individuals has been fostered by the unrealistic expectations of society; facilitated by the complicity of institutions and organisations; and sanctioned by the inaction of supposed gate-keepers. Re-defining misconduct as occurring on a continuum from irresponsible to fraudulent is the first step in confronting this inconvenient truth. Implementing and evaluating multiple strategies targeting systems and individuals that promote the responsible conduct of research, rather than merely exposing serious instances of misconduct by individuals, is urgently required to restore faith in the aspirations, integrity, and results of scientific research.","PeriodicalId":89196,"journal":{"name":"Mens sana monographs","volume":"10 1","pages":"158-80"},"PeriodicalIF":0.0,"publicationDate":"2012-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.4103/0973-1229.91426","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"30659085","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3

Suicide and antidepressants: what current evidence indicates. 自杀和抗抑郁药:目前的证据表明。

Mens sana monographs Pub Date : 2012-01-01 DOI: 10.4103/0973-1229.87287

Anil Nischal, Adarsh Tripathi, Anuradha Nischal, J K Trivedi

{"title":"Suicide and antidepressants: what current evidence indicates.","authors":"Anil Nischal, Adarsh Tripathi, Anuradha Nischal, J K Trivedi","doi":"10.4103/0973-1229.87287","DOIUrl":"https://doi.org/10.4103/0973-1229.87287","url":null,"abstract":"The documented efficacy and long-term benefit of antidepressants in patients with recurrent forms of severe anxiety or depressive disorders support their use in those individuals with these disorders, who experience suicidal thoughts or behavior. In general, it is assumed that antidepressants are beneficial for all symptoms of depression, including suicidality. However, some evidence suggests that Selective Serotonin Reuptake Inhibitors [SSRIs] may cause worsening of suicidal ideas in vulnerable patients. Systematic reviews and pooled analysis of experimental, observational, and epidemiological studies have investigated the use of SSRIs and their association with suicidality. Taking account of the methodological limitations of these studies, the current evidence fails to provide a clear relationship between their use and risk of suicidality in adults. However, in children and adolescents, there appears to be a bit of increased risk of suicidal ideations and attempts, but not of completed suicides. This risk can be anticipated and managed clinically. Clinicians are, therefore, advised to maintain a close follow-up during the initial treatment periods and remain vigilant of this risk. This advisory, however, should not deter clinicians from the use of effective dosages of antidepressants for a sufficient period of time, in every age group of patients, when clinically needed, and if found suitable otherwise.","PeriodicalId":89196,"journal":{"name":"Mens sana monographs","volume":"10 1","pages":"33-44"},"PeriodicalIF":0.0,"publicationDate":"2012-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.4103/0973-1229.87287","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"30659784","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 33

Revised Template for MSM Submissions 2012. 修订的MSM提交模板2012。

Mens sana monographs Pub Date : 2012-01-01 DOI: 10.4103/0973-1229.103095

Ajai R Singh

引用次数: 0

Stigma of Mental Illness-1: Clinical reflections. 精神疾病的耻辱-1：临床反思。

Mens sana monographs Pub Date : 2012-01-01 DOI: 10.4103/0973-1229.90181

Amresh Shrivastava, Megan Johnston, Yves Bureau

引用次数: 0

A Slice of a Postgraduate Medical Resident's Life. 研究生住院医师的生活片段。

Mens sana monographs Pub Date : 2012-01-01 DOI: 10.4103/0973-1229.87288

Dilip Gude

引用次数: 0

On being the Editor of the Medical Journal of Australia: Living dangerously. 作为澳大利亚医学杂志的编辑:危险的生活。

Mens sana monographs Pub Date : 2012-01-01 DOI: 10.4103/0973-1229.91295

Martin B Van Der Weyden

引用次数: 1

Psychopharmacology of schizophrenia: The Future Looks Bleak. 精神分裂症的精神药理学:前景黯淡。

Mens sana monographs Pub Date : 2012-01-01 DOI: 10.4103/0973-1229.91293

Chittaranjan Andrade, Rajiv Radhakrishnan, Praveen P Fernandes

{"title":"Psychopharmacology of schizophrenia: The Future Looks Bleak.","authors":"Chittaranjan Andrade, Rajiv Radhakrishnan, Praveen P Fernandes","doi":"10.4103/0973-1229.91293","DOIUrl":"https://doi.org/10.4103/0973-1229.91293","url":null,"abstract":"Introduction: More than half a century after the introduction of effective pharmacotherapy for the illness, in most patients schizophrenia remains a chronic, relapsing condition with poor long-term outcomes.Methods: We examine the pharmacological treatment of schizophrenia from different perspectives to understand why there have not been significant advances, and to consider what the future might hold in store.Results: We argue that the treatment of schizophrenia addresses the phenotype and not the cause; that the causes may not be treatable even if identifiable; that secondary prevention approaches involving treating the phenotype before full-fledged illness develops have, so far, not yielded promising results; and that shifting the focus of treatment from dopamine to other neurotransmitter systems is merely a tertiary prevention approach which will not reverse the extensive structural and functional pathology of schizophrenia.Conclusions: We believe that, given the current state of our knowledge of the illness, the future of the pharmacotherapy of schizophrenia looks bleak.","PeriodicalId":89196,"journal":{"name":"Mens sana monographs","volume":"10 1","pages":"4-12"},"PeriodicalIF":0.0,"publicationDate":"2012-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.4103/0973-1229.91293","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"30660897","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 6