Biomedical Engineering / Biomedizinische Technik最新文献_第6页

Frontmatter 头版头条

4区医学

Biomedical Engineering / Biomedizinische Technik Pub Date : 2023-02-01 DOI: 10.1515/bmt-2023-frontmatter1

引用次数: 0

Towards technically controlled bioreactor maturation of tissue-engineered heart valves. 组织工程心脏瓣膜的技术控制生物反应器成熟。

IF 1.7 4区医学

Biomedical Engineering / Biomedizinische Technik Pub Date : 2022-09-13 Print Date: 2022-12-16 DOI: 10.1515/bmt-2021-0379

Kirsten Voß, Maximilian P Werner, Jonas Gesenhues, Vytautas Kučikas, Marc van Zandvoort, Stefan Jockenhoevel, Thomas Schmitz-Rode, Dirk Abel

{"title":"Towards technically controlled bioreactor maturation of tissue-engineered heart valves.","authors":"Kirsten Voß, Maximilian P Werner, Jonas Gesenhues, Vytautas Kučikas, Marc van Zandvoort, Stefan Jockenhoevel, Thomas Schmitz-Rode, Dirk Abel","doi":"10.1515/bmt-2021-0379","DOIUrl":"https://doi.org/10.1515/bmt-2021-0379","url":null,"abstract":"Bioreactors are important tools for the pre-conditioning of tissue-engineered heart valves. The current state of the art mostly provides for timed, physical and biochemical stimulation in the bioreactor systems according to standard protocols (SOP). However, this does not meet to the individual biological variability of living tissue-engineered constructs. To achieve this, it is necessary to implement (i) sensory systems that detect the actual status of the implant and (ii) controllable bioreactor systems that allow patient-individualized pre-conditioning. During the maturation process, a pulsatile transvalvular flow of culture medium is generated within the bioreactor. For the improvement of this conditioning procedure, the relationship between the mechanical and biochemical stimuli and the corresponding tissue response has to be analyzed by performing reproducible and comparable experiments. In this work, a technological framework for maturation experiments of tissue-engineered heart valves in a pulsating bioreactor is introduced. The aim is the development of a bioreactor system that allows for continuous control and documentation of the conditioning process to increase reproducibility and comparability of experiments. This includes hardware components, a communication structure and software including online user communication and supervision. Preliminary experiments were performed with a tissue-engineered heart valve to evaluate the function of the new system. The results of the experiment proof the adequacy of the setup. Consequently, the concept is an important step for further research towards controlled maturation of tissue-engineered heart valves. The integration of molecular and histological sensor systems will be the next important step towards a fully automated, self-controlled preconditioning system.","PeriodicalId":8900,"journal":{"name":"Biomedical Engineering / Biomedizinische Technik","volume":"67 6","pages":"461-470"},"PeriodicalIF":1.7,"publicationDate":"2022-09-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"33468650","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Evaluation method of ex vivo porcine liver reduced scattering coefficient during microwave ablation based on temperature. 基于温度的离体猪肝微波消融减散射系数评价方法。

IF 1.7 4区医学

Biomedical Engineering / Biomedizinische Technik Pub Date : 2022-09-12 Print Date: 2022-12-16 DOI: 10.1515/bmt-2022-0189

Xiaofei Jin, Wenwen Liu, Yiran Li, Lu Qian, Qiaoqiao Zhu, Weitao Li, Zhiyu Qian

{"title":"Evaluation method of ex vivo porcine liver reduced scattering coefficient during microwave ablation based on temperature.","authors":"Xiaofei Jin, Wenwen Liu, Yiran Li, Lu Qian, Qiaoqiao Zhu, Weitao Li, Zhiyu Qian","doi":"10.1515/bmt-2022-0189","DOIUrl":"https://doi.org/10.1515/bmt-2022-0189","url":null,"abstract":"The principle of microwave ablation (MWA) is to cause irreversible damage (protein coagulation, necrosis, etc.) to tumor cells at a certain temperature by heating, thereby destroying the tumor. We have long used functional near-infrared spectroscopy (fNIRs) to monitor clinical thermal ablation efficacy. After a lot of experimental verification, it can be found that there is a clear correlation between the reduced scattering coefficient and the degree of tissue damage. During the MWA process, the reduced scattering coefficient has a stable change. Therefore, both temperature (T) and reduced scattering coefficient ( <math> <mrow><msubsup><mi>μ</mi> <mi>s</mi> <mo>'</mo></msubsup> </mrow> </math> ) are related to the thermal damage of the tissue. This paper mainly studies the changing law of T and <math> <mrow><msubsup><mi>μ</mi> <mi>s</mi> <mo>'</mo></msubsup> </mrow> </math> during MWA and establishes a relationship model. The two-parameter simultaneous acquisition system was designed and used to obtain the T and <math> <mrow><msubsup><mi>μ</mi> <mi>s</mi> <mo>'</mo></msubsup> </mrow> </math> of the ex vivo porcine liver during MWA. The correlation model between T and <math> <mrow><msubsup><mi>μ</mi> <mi>s</mi> <mo>'</mo></msubsup> </mrow> </math> is established, enabling the quantitative estimation of <math> <mrow><msubsup><mi>μ</mi> <mi>s</mi> <mo>'</mo></msubsup> </mrow> </math> of porcine liver based on T. The maximum and the minimum relative errors of <math> <mrow><msubsup><mi>μ</mi> <mi>s</mi> <mo>'</mo></msubsup> </mrow> </math> are 79.01 and 0.39%, respectively. Through the electromagnetic simulation of the temperature field during MWA, 2D and 3D fields of reduced scattering coefficient can also be obtained using this correlation model. This study contributes to realize the preoperative simulation of the optical parameter field of microwave ablation and provide 2D/3D therapeutic effect for clinic.","PeriodicalId":8900,"journal":{"name":"Biomedical Engineering / Biomedizinische Technik","volume":"67 6","pages":"491-501"},"PeriodicalIF":1.7,"publicationDate":"2022-09-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"33457301","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

A new method for successful indirect bonding in relation to bond strength. 一种与粘接强度相关的成功间接粘接新方法。

IF 1.7 4区医学

Biomedical Engineering / Biomedizinische Technik Pub Date : 2022-08-24 Print Date: 2022-10-26 DOI: 10.1515/bmt-2022-0147

Thomas Wendl, Christine Bandl, Wolfgang Kern, Brigitte Wendl, Peter Proff

{"title":"A new method for successful indirect bonding in relation to bond strength.","authors":"Thomas Wendl, Christine Bandl, Wolfgang Kern, Brigitte Wendl, Peter Proff","doi":"10.1515/bmt-2022-0147","DOIUrl":"https://doi.org/10.1515/bmt-2022-0147","url":null,"abstract":"The aim of the work was to develop a new transfer method for indirect bonding of brackets to improve the bond strength by applying a uniform contact pressure over the entire dental arch. This has a great potential to reduce the bracket loss rate during clinical treatment. A suitable shape memory polymer (SMP) was selected and prepared in the chemistry laboratory. This SMP applies a force to the brackets during bonding and thus increases the bond strength by applying uniform contact pressure. Various transfer trays were equipped with SMP platelets and the transfer of brackets from the plaster model to the real human tooth model was performed in vitro. The transfer accuracy and bond strength of the bonded brackets were investigated by 3D-overlay and shear tests, respectively. The transfer accuracy was technique sensitive and showed higher accuracy for the trays with SMPs and self-curing silicones than for the vacuum formed trays with SMPs. The bond strength of the indirectly bonded brackets with SMPs was on average 1-2 MPa higher than the bond strength of the brackets indirectly bonded with a conventional two-layer vacuum formed tray without SMPs. Thus, transfer trays with SMPs can provide a significant improvement in bond strength during indirect bonding after appropriate adjustment.","PeriodicalId":8900,"journal":{"name":"Biomedical Engineering / Biomedizinische Technik","volume":"67 5","pages":"403-410"},"PeriodicalIF":1.7,"publicationDate":"2022-08-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40420639","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Mechanical response of different frameworks for maxillary all-on-four implant-supported fixed dental prosthesis: 3D finite element analysis. 上颌全-四种植体固定义齿不同框架的力学响应:三维有限元分析。

IF 1.7 4区医学

Biomedical Engineering / Biomedizinische Technik Pub Date : 2022-08-17 Print Date: 2022-10-26 DOI: 10.1515/bmt-2022-0176

Zekiye Begüm Güçlü, Ayhan Gürbüz, Gonca Deste Gökay, Rukiye Durkan, Perihan Oyar

{"title":"Mechanical response of different frameworks for maxillary all-on-four implant-supported fixed dental prosthesis: 3D finite element analysis.","authors":"Zekiye Begüm Güçlü, Ayhan Gürbüz, Gonca Deste Gökay, Rukiye Durkan, Perihan Oyar","doi":"10.1515/bmt-2022-0176","DOIUrl":"https://doi.org/10.1515/bmt-2022-0176","url":null,"abstract":"This study's purpose is to assess the stress distribution in the peri-implant bone, implants, and prosthetic framework using two different posterior implant angles. All-on-four maxillary prostheses fabricated from feldspathic-ceramic-veneered zirconia-reinforced lithium silicate (ZLS) and feldspathic-ceramic-veneered cobalt-chromium (CoCr) were designed with 17 or 30-degree-angled posterior implants. Posterior cantilever and frontal vertical loads were applied to all models. The distribution of maximum and minimum principal stresses (σmax and σmin) and von Mises stress (σVM) was evaluated. Under posterior cantilever load, with an increase in posterior implant angle, σmax decreased by 4 and 7 MPa in the cortical bone when ZLS and CoCr were used as a prosthetic framework, respectively. Regardless of the framework material, 17-degree-angled posterior implants showed the highest σVM (541.36 MPa under posterior cantilever load; 110.79 MPa under frontal vertical load) values. Regardless of the posterior implant angle, ZLS framework showed the highest σVM (91.59 MPa under posterior cantilever load; 218.99 MPa under frontal vertical load) values. Increasing implant angle from 17 to 30° caused a decrease in σmax values in the cortical bone. Designs with 30-degree posterior implant angles and ZLS framework material may be preferred in All-on-four implant-supported fixed complete dentures.","PeriodicalId":8900,"journal":{"name":"Biomedical Engineering / Biomedizinische Technik","volume":"67 5","pages":"419-428"},"PeriodicalIF":1.7,"publicationDate":"2022-08-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40617677","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Biomagnetic signals recorded during transcranial magnetic stimulation (TMS)-evoked peripheral muscular activity. 经颅磁刺激(TMS)诱发外周肌肉活动时记录的生物磁信号。

IF 1.7 4区医学

Biomedical Engineering / Biomedizinische Technik Pub Date : 2022-08-15 Print Date: 2022-10-26 DOI: 10.1515/bmt-2021-0019

Geoffrey Z Iwata, Yinan Hu, Arne Wickenbrock, Tilmann Sander, Muthuraman Muthuraman, Venkata Chaitanya Chirumamilla, Sergiu Groppa, Qishan Liu, Dmitry Budker

{"title":"Biomagnetic signals recorded during transcranial magnetic stimulation (TMS)-evoked peripheral muscular activity.","authors":"Geoffrey Z Iwata, Yinan Hu, Arne Wickenbrock, Tilmann Sander, Muthuraman Muthuraman, Venkata Chaitanya Chirumamilla, Sergiu Groppa, Qishan Liu, Dmitry Budker","doi":"10.1515/bmt-2021-0019","DOIUrl":"https://doi.org/10.1515/bmt-2021-0019","url":null,"abstract":"Transcranial magnetic stimulation (TMS) has widespread clinical applications from diagnosis to treatment. We combined TMS with non-contact magnetic detection of TMS-evoked muscle activity in peripheral limbs to explore a new diagnostic modality that enhances the utility of TMS as a clinical tool by leveraging technological advances in magnetometry. We recorded measurements in a regular hospital room using an array of optically pumped magnetometers (OPMs) inside a portable shield that encloses only the forearm and hand of the subject. We present magnetomyograms (MMG)s of TMS-evoked movement in a human hand, together with a simultaneous surface electromyograph (EMG) data. The biomagnetic signals recorded in the MMG provides detailed spatial and temporal information that is complementary to that of the electric signal channels. Moreover, we identify features in the magnetic recording beyond that of the EMG. This system demonstrates the value of biomagnetic signals in TMS-based clinical approaches and widens its availability and practical potential.","PeriodicalId":8900,"journal":{"name":"Biomedical Engineering / Biomedizinische Technik","volume":"67 5","pages":"333-344"},"PeriodicalIF":1.7,"publicationDate":"2022-08-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40609229","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 9

A comparative study of the spectrogram, scalogram, melspectrogram and gammatonegram time-frequency representations for the classification of lung sounds using the ICBHI database based on CNNs. 基于cnn的ICBHI数据库肺音分类的谱图、尺度图、mel谱图和伽玛图时频表示的比较研究。

IF 1.7 4区医学

Biomedical Engineering / Biomedizinische Technik Pub Date : 2022-08-08 Print Date: 2022-10-26 DOI: 10.1515/bmt-2022-0180

Zakaria Neili, Kenneth Sundaraj

{"title":"A comparative study of the spectrogram, scalogram, melspectrogram and gammatonegram time-frequency representations for the classification of lung sounds using the ICBHI database based on CNNs.","authors":"Zakaria Neili, Kenneth Sundaraj","doi":"10.1515/bmt-2022-0180","DOIUrl":"https://doi.org/10.1515/bmt-2022-0180","url":null,"abstract":"In lung sound classification using deep learning, many studies have considered the use of short-time Fourier transform (STFT) as the most commonly used 2D representation of the input data. Consequently, STFT has been widely used as an analytical tool, but other versions of the representation have also been developed. This study aims to evaluate and compare the performance of the spectrogram, scalogram, melspectrogram and gammatonegram representations, and provide comparative information to users regarding the suitability of these time-frequency (TF) techniques in lung sound classification. Lung sound signals used in this study were obtained from the ICBHI 2017 respiratory sound database. These lung sound recordings were converted into images of spectrogram, scalogram, melspectrogram and gammatonegram TF representations respectively. The four types of images were fed separately into the VGG16, ResNet-50 and AlexNet deep-learning architectures. Network performances were analyzed and compared based on accuracy, precision, recall and F1-score. The results of the analysis on the performance of the four representations using these three commonly used CNN deep-learning networks indicate that the generated gammatonegram and scalogram TF images coupled with ResNet-50 achieved maximum classification accuracies.","PeriodicalId":8900,"journal":{"name":"Biomedical Engineering / Biomedizinische Technik","volume":"67 5","pages":"367-390"},"PeriodicalIF":1.7,"publicationDate":"2022-08-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40601433","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 6

A method to detect sleep apnea using residual attention mechanism network from single-lead ECG signal. 利用单导联心电信号残余注意机制网络检测睡眠呼吸暂停的方法。

IF 1.7 4区医学

Biomedical Engineering / Biomedizinische Technik Pub Date : 2022-08-04 Print Date: 2022-10-26 DOI: 10.1515/bmt-2022-0067

Tao Wang, Changhua Lu, Yining Sun, Hengyang Fang, Weiwei Jiang, Chun Liu

{"title":"A method to detect sleep apnea using residual attention mechanism network from single-lead ECG signal.","authors":"Tao Wang, Changhua Lu, Yining Sun, Hengyang Fang, Weiwei Jiang, Chun Liu","doi":"10.1515/bmt-2022-0067","DOIUrl":"https://doi.org/10.1515/bmt-2022-0067","url":null,"abstract":"Sleep apnea is a sleep disorder caused by weakened or suspended breathing during sleep, which seriously affects the work and health of patients. The traditional polysomnography (PSG) detection process is complicated and expensive, which has attracted researchers to explore a rapid detection method based on single-lead ECG signals. However, existing ECG-based sleep apnea detection methods have certain limitations and complexities, mainly relying on human-crafted features. To solve the problem, the paper develops a sleep apnea detection method based on a residual attention mechanism network. The method uses the RR interval signal and the R-peak signal derived from the ECG signal as input, realizes feature extraction through the residual network (ResNet), and adds the SENet attention mechanism to deepen the mining of channel features. Experimental results show that the per-segment accuracy of the proposed method can reach 86.2%. Compared with existing works, its accuracy has increased by 1.1-8.1%. These results show that the proposed residual attention network can effectively use ECG signals to quickly detect sleep apnea. Meanwhile, compared with existing works, the proposed method overcomes the limitations and complexity of human-crafted features in sleep apnea detection research.","PeriodicalId":8900,"journal":{"name":"Biomedical Engineering / Biomedizinische Technik","volume":"67 5","pages":"357-365"},"PeriodicalIF":1.7,"publicationDate":"2022-08-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40667135","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Abstracts of the 2022 Joint Annual Conference of the Austrian (ÖGBMT), German (VDE DGBMT) and Swiss (SSBE) Societies for Biomedical Engineering, including the 14th Vienna International Workshop on Functional Electrical Stimulation 奥地利(ÖGBMT)、德国(VDE DGBMT)和瑞士(SSBE)生物医学工程学会2022年联合年会摘要，包括第14届维也纳功能电刺激国际研讨会

IF 1.7 4区医学

Biomedical Engineering / Biomedizinische Technik Pub Date : 2022-08-01 DOI: 10.1515/bmt-2022-2001

D. Baumgarten

引用次数: 0

Stratification of risk of atherosclerotic plaque using Hu's moment invariants of segmented ultrasonic images. 利用分段超声图像的Hu不变矩对动脉粥样硬化斑块风险进行分层。

IF 1.7 4区医学

Biomedical Engineering / Biomedizinische Technik Pub Date : 2022-07-15 Print Date: 2022-10-26 DOI: 10.1515/bmt-2021-0044

Smitha Balakrishnan, Paul K Joseph

{"title":"Stratification of risk of atherosclerotic plaque using Hu's moment invariants of segmented ultrasonic images.","authors":"Smitha Balakrishnan, Paul K Joseph","doi":"10.1515/bmt-2021-0044","DOIUrl":"https://doi.org/10.1515/bmt-2021-0044","url":null,"abstract":"Myocardial infarction is one of the major life-threatening diseases. The cause is atherosclerosis i.e. the occlusion of the coronary artery by deposition of plaque on its walls. The severity of plaque deposition in the artery depends on the characteristics of the plaque. Hence, the classification of the type of plaque is crucial for assessing the risk of atherosclerosis and predicting the chances of myocardial infarction. This paper proposes prediction of atherosclerotic risk by non-invasive ultrasound image segmentation and textural feature extraction. The intima-media complex is segmented using a snakes-based segmentation algorithm on the arterial wall in the ultrasound images. Then, the plaque is extracted from the segmented intima-media complex. The features of the plaque are obtained by computing Hu's moment invariants. Visual pattern recognition independent of position, size, orientation and parallel projection could be done using these moment invariants. For the classification of the features of the plaque, an SVM classifier is used. The performance shows improvement in accuracy using lesser number of features than previous works. The reduction in feature size is achieved by incorporating segmentation in the pre-processing stage. Tenfold cross-validation protocol is used for training and testing the classifier. An accuracy of 97.9% is obtained with only two features. This proposed technique could work as an adjunct tool in quick decision-making for cardiologists and radiologists. The segmentation step introduced in the preprocessing stage improved the feature extraction technique. An improvement in performance is achieved with much less number of features.","PeriodicalId":8900,"journal":{"name":"Biomedical Engineering / Biomedizinische Technik","volume":"67 5","pages":"391-402"},"PeriodicalIF":1.7,"publicationDate":"2022-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40534458","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3