HIV therapy最新文献_第2页

HIV therapy Pub Date : 2010-10-25 DOI: 10.2217/HIV.10.46

A. Chirianni, V. Esposito

引用次数: 2

The impact of baseline characteristics on virologic response to etravirine: 48-week pooled analysis of DUET-1 and DUET-2 基线特征对依曲维林病毒学反应的影响:对DUET-1和DUET-2的48周汇总分析

HIV therapy Pub Date : 2010-10-25 DOI: 10.2217/HIV.10.41

P. Cahn, R. Haubrich, C. Katlama, F. Goebel, F. Suter, M. Peeters, J. Vingerhoets, R. Sinha, J. Witek

引用次数: 10

Politics and policy in HIV/AIDS: the road ahead for South Africa 艾滋病毒/艾滋病的政治和政策:南非的前进道路

HIV therapy Pub Date : 2010-10-25 DOI: 10.2217/HIV.10.34

H. Coovadia

引用次数: 0

Noninfectious HIV-related comorbidities and HAART toxicities: choosing alternative antiretroviral strategies 非传染性hiv相关合并症和HAART毒性:选择替代性抗逆转录病毒策略

HIV therapy Pub Date : 2010-10-25 DOI: 10.2217/HIV.10.44

L. Gazzola, C. Tincati, A. Monforte

引用次数: 6

Immune reconstitution inflammatory syndrome in HIV-positive patients: a relatively new and not fully understood phenomenon 艾滋病毒阳性患者的免疫重建炎症综合征:一个相对较新的和尚未完全了解的现象

HIV therapy Pub Date : 2010-10-25 DOI: 10.2217/HIV.10.45

G. Arendt, T. Nolting

引用次数: 1

HIV treatment in the criminal justice system 刑事司法系统中的艾滋病毒治疗

HIV therapy Pub Date : 2010-10-25 DOI: 10.2217/HIV.10.43

M. Milloy, E. Wood

{"title":"HIV treatment in the criminal justice system","authors":"M. Milloy, E. Wood","doi":"10.2217/HIV.10.43","DOIUrl":"https://doi.org/10.2217/HIV.10.43","url":null,"abstract":"The advent of HAART has resulted in a dramatic decline in HIV-related morbidity and mortality among those accessing HIV treatment [1]. Fortunately, efforts to simplify regimens and scale up treatment systems have led to individuals being engaged in treatment in numbers and locales that were unimaginable just 10 years ago. Still, some seropositive populations have not benefited equally from advancements in HIV treatment. Studies of HIV-seropositive individuals who use injection drugs (IDU) on HAART confirm that adherent individuals can derive similar benefits as adherent individuals from other risk groups [2]. Nevertheless, coverage of HAART among IDU remains low, not only in areas such as the Russian Federation and other countries of the former Soviet Union and China, where a substantial and increasing proportion of new infections are linked to injection drug use, but also in settings with advanced healthcare systems [3]. Once on HAART, HIVseropositive IDU often achieve lower levels of adherence and are more likely to prematurely discontinue therapy [4,5]. As a result of the individual and, likely, community [6] benefits of attracting and maintaining IDU on HAART, there is an urgent need to identify and remove barriers to access and adherence to HAART among IDU [7].","PeriodicalId":88510,"journal":{"name":"HIV therapy","volume":"3 1","pages":"519-522"},"PeriodicalIF":0.0,"publicationDate":"2010-10-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86336240","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Clinical use of raltegravir: a review 雷替重力韦的临床应用综述

HIV therapy Pub Date : 2010-10-25 DOI: 10.2217/HIV.10.38

E. Nunes, Marília Santini de Oliveira, B. Grinsztejn

引用次数: 3

HIV treatment in US prisons. 美国监狱的艾滋病治疗。

HIV therapy Pub Date : 2010-09-03 DOI: 10.2217/hiv.10.35

Sarah E Wakeman, Josiah D Rich

引用次数: 24

Recent developments in HIV-related kidney disease. hiv相关肾脏疾病的最新进展。

HIV therapy Pub Date : 2010-09-01 DOI: 10.2217/hiv.10.42

Michelle M Estrella, Derek M Fine, Mohamed G Atta

{"title":"Recent developments in HIV-related kidney disease.","authors":"Michelle M Estrella, Derek M Fine, Mohamed G Atta","doi":"10.2217/hiv.10.42","DOIUrl":"https://doi.org/10.2217/hiv.10.42","url":null,"abstract":"<p><p>Although kidney disease has been a recognized complication of HIV infection since the beginning of the HIV epidemic, its epidemiology, underlying causes and treatment have evolved in developed countries where HAART has been widely available. HIV-associated nephropathy and HIV immune complex-mediated kidney disease were the prominent renal diagnoses in the earlier period of the HIV epidemic. While HIV immune complex-mediated kidney disease remains a common finding among HIV-infected individuals with kidney disease, the incidence of HIV-associated nephropathy has been diminishing in developed countries. The role of the metabolic effects of long-term HAART exposure and nephrotoxicity of certain antiretroviral medications on the development and progression of chronic kidney disease is now of increasing concern. The long-term clinical implications of acute kidney injury among HIV-infected persons are increasingly recognized. Kidney disease in HIV-infected persons continues to be a major risk factor for morbidity and mortality in this patient population; therefore, early recognition and treatment of kidney disease are imperative in lessening the impact of kidney disease on the health of HIV-infected individuals. This review focuses on recent developments and ongoing challenges in the understanding, diagnosis and management of HIV-related kidney disease.</p>","PeriodicalId":88510,"journal":{"name":"HIV therapy","volume":"4 5","pages":"589-603"},"PeriodicalIF":0.0,"publicationDate":"2010-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.2217/hiv.10.42","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"29679823","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 22

Origin of HIV/AIDS and risk for ongoing zoonotic transmissions from nonhuman primates to humans 艾滋病毒/艾滋病的起源和非人类灵长类动物向人类持续传播的人畜共患疾病的风险

HIV therapy Pub Date : 2010-07-07 DOI: 10.2217/HIV.10.33

M. Peeters, S. A. Mundeke, E. M. Ngole, E. Delaporte

{"title":"Origin of HIV/AIDS and risk for ongoing zoonotic transmissions from nonhuman primates to humans","authors":"M. Peeters, S. A. Mundeke, E. M. Ngole, E. Delaporte","doi":"10.2217/HIV.10.33","DOIUrl":"https://doi.org/10.2217/HIV.10.33","url":null,"abstract":"Origin & history of the HIV/ AIDS epidemic HIV/AIDS ranks as one of the most important infectious diseases to have emerged in the past century and continues to be one of the most serious public health threats of the 21st cen‐ tury. AIDS was first recognized in the early 1980s and today, approximately 30 years later, more than 33 million people worldwide are infected with HIV and more than 25 million people have died from the disease. Similar to the majority of emerging infectious diseases, HIV/ AIDS is also of zoonotic origin and occurred when an established SIV switched from pri‐ mates into humans [1–3]. The closest simian relatives of HIV‐1 are SIVcpz in chimpanzees (Pan troglodytes troglodytes) and SIVgor in goril‐ las (Gorilla gorilla) from West Central Africa [4,5]. SIVsmm in sooty mangabeys (Cercocebus atys) from West Africa are the closest relatives of HIV‐2 [6,7]. Although the exact conditions and circumstances of cross‐species transmis‐ sion of SIVs from primates to humans remain unknown, human exposure to blood or other secretions of infected primates, through hunting and butchering of primate bushmeat, represents the most plausible source for human infection. In addition, bites and other injuries caused by primates kept as pet animals can favor a possible viral transmission.","PeriodicalId":88510,"journal":{"name":"HIV therapy","volume":"38 1","pages":"387-390"},"PeriodicalIF":0.0,"publicationDate":"2010-07-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81619409","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3